Date Started

Name of Drug (Brand) Plavix

Generic Name

Drug Classification

Route of Administrati on Oral 75ng/tab OD

Action, Side Effects, Adverse Effects Action: Inhibits platelet aggregation by blocking ADP receptors on platelets, preventing clumping of platelets Side Effects/ Adverse Effects: CNS: Headache, dizziness, weakness, syncope, flushing CV: Hypertension, edema Dermatologic: Rash, pruritus GI: Nausea, GI distress, constipation, diarrhea, GI bleed Other: Increased bleeding risk

Indication Applicable to Patients Condition Treatment of patients at risk for ischemic events history of MI, ischemic stroke, peripheral artery disease

Contraindication Nursing Consideration

December 3, 2012

Clopidogrel bisulfate

Adenosine dophosphate (ADP) receptor antagonist Antiplatelet

Contraindicated with allergy to clopidogrel, active pathological bleeding such as peptic ulcer or intracranial hemorrhage, lactation.

Assess for symptoms of stroke, MI during treatment

Monitor liver function studies: AST, ALT, bilirubin, creatinine if patient is on long-term therapy

Monitor blood studies: CBC,Hgb, Hct, protime, cholesterol if the patient is on long-term therapy; thrombocytopenia and neutropenia may occur.