Notes on Philippine Medically Important Protozoans Part 4 (Trypanosomes and Leismania spp.

)Meccar
Moniem Elino, BSBio IV , Davao Doctors College Instructor: Mrs. Chalee Sienes-Reyes, RMT, MSMT, Ph.D Reference: Philippine textbook of Medical Parasitology 2nd ed.(2004) UP. Edited by Vicente Y. Belizario, Jr. and Winifreda U. de Leon

Disease American Trypanosomiasis or Chagas Disease Gambian or West African Sleeping Sickness Rhodesian or East African Sleeping Sickness

Vector

Portal of entry

Infective Stage

Infective Stage for Vector

T. cruzi

Infected Triatomine bug

Break Skn or intact mucous

Metacyclic Trypomastigote

Trypomastigote

T. brucei gambiense

Infected Tse-Tse Flies

Break Skn or intact mucous

Metacyclic Trypomastigote

Trypomastigote

T. brucei rhodesiense

Infected Tse-Tse Flies

Break Skn or intact mucous

Metacyclic Trypomastigote

Trypomastigote

Leishmania donovani

Visceral Leishmanisis or KALAAZAR

Sand/Phlebotomus Fly

Skin/ Macrophages and monocytes of spleen, liver, bone marrow Skin/ Macrophages and monocytes of spleen, liver, bone marrow Skin/ Macrophages and monocytes of spleen, liver, bone marrow

Promastigote

Amastigote

Leishmania tropica

Cutaneous Leishmaniasis

Sand/Phlebotomus Fly

Promastigote

Amastigote

Leishmania braziliense

Mucocutaneous Leishmaniasis or ESPUNDIA

Sand/Phlebotomus Fly

Promastigote

Amastigote