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ZINC SULFATE OTC and prescription drug: Orazinc, PMS-Egozinc (CAN), Verazinc, Zincate Pregnancy Category C Drug Classes

Mineral Therapeutic actions Natural element that is essential for growth and tissue repair; acts as an integral part of essential enzymes in protein and carbohydrate metabolism. Indications Dietary supplement to treat or prevent zinc deficiencies Treatment of Wilson's disease (Galzin) Unlabeled uses: acrodermatitis enteropathica and delayed wound healing associated with zinc deficiency; treatment of acne, rheumatoid arthritis; treatment of the common cold Contraindications/cautions Contraindications: pregnancy and lactation (recommended dietary allowance is needed, but not supplemental replacement). Dosage Available Forms: Tablets--15, 25, 45, 50 mg zinc; 1.4, 2, 7, 11 mg zinc Adult Recommended dietary allowance (RDA): 12---15 mg/d PO; pregnancy RDA, 15 mg/d PO; lactation RDA, 6 mg/d PO for the first 6 mo; then 4 mg/d for the next 6 mo. Dietary supplement: 25---50 mg zinc/d PO. Pediatric RDA:

5---10 mg/d PO. Pharmacokinetics Route Onset Peak Oral Slow Delayed Metabolism: Hepatic, T: unknown Distribution: Crosses placenta; may enter breast milk Excretion: Feces Adverse Effects GI: Vomiting, nausea Nursing Considerations Assessment History: Lactation, pregnancy Physical: Bowel sounds, normal output; serum zinc levels Implementation Give with food if GI upset occurs; avoid bran and other high-fiber foods, calcium and phosphates that may interfere with absorption. Ensure that patient receives only the prescribed dosage. Avoid overdose. Drug-specific teaching points Take this drug exactly as prescribed. Do not exceed prescribed dosage. Take with food, but avoid taking it with bran and other high-fiber foods, dairy products that may interfere with absorption. The following side effects may occur: nausea, vomiting (take drug with food). Report severe nausea and vomiting, restlessness, fatigue, lethargy. Adverse effects in Italic are most common; those in Bold are life-threatening.