kmpitative inhibitor ==km increase ,vmax same non kmpitative inhibitor==== km not increased, vmax decreased ALL DH enzymes

produce NADH) Glucagon puts Phosphate ON (phosphorylates); and INversely INsulin does the oppo site (dephosphorylate) This is a good way to remember what enzymes of which pathways are active/inactiv e in phosphorylated/dephosphorylated form eg. Insulin activates Glycolysis, and Glycogen synthesis, so the enzymes that it activates in those pathways will be active in DEphosphorylated form. and: Glucagon activates Glycogenolysis and Gluconeogenesis, so the enzymes that it activates in those pathways will be active in Phosphorylated form. Steps of glycolysis: Goodness Gracious Father Franklin Did Go By Picking Pumpkins to Prepare Pie Thus, the first emphasized letter of each of the above emphasized words relates to the following steps in glycolysis: Glucose Glucose-6-Phosphate Fructose-6-phosphate Fructose-1,6-biphosphate Dihydroxyacetone phosphate (DHAP) Glyceraldehyde-3-phosphate 1,3-Biphosphoglycerate 3-Phosphoglycerate 2-Phosphoglycerate Phosphoenolpyruvate Pyruvate The enzymes involved in the above steps can be remembered with the following mem ory aid: High Profile People Act Too Glamorous, Picture Posing Every Place Again, the first emphasized letter of each of the above emphasized words relates to the following enzymes involved in the above steps in glycolysis: Hexokinase Phosphofructo isomerase Phoshofructokinase Aldolase Triose phosphate isomerase Glyceraldehyde-3-phosphate dehydrogenase Phosphoglycerokinase Phosphoglyceromutase Enolase Pyruvate kinase Citric Acid Cycle Compounds involved in cycle: Our City Is Kept Safe and Sound From Malace

This corresponds to: Oxalacetate Citrate Isocitrate Alpha-ketoglutamate Succinyl-coA Succinate Fumarate Malate Enzymes involved in cycle: CAIK Sounds So Fucking Mint. This corresponds to: Citrate synthase Aconitase Iso-citrate dehydrogenase Alpha-Ketoglutarate dehydrogenase Succinyl-coA synthetase Succinate dehydrogenase Fumerase Malate dehydrogenase ENDOTOXIN: Endothelial cells/ Edema Negative (gram- bacteria) DIC/ Death Outer membrane TNF O-antigen X-tremely heat stable IL-1 Nitric oxide/ Neutrophil chemotaxis Acute ischemia: signs [especially limbs] 6 P's: Pain Pallor Pulselessness Paralysis Paraesthesia Perishingly cold Functions of the different RNA polymerases I, II and III? I,II,II = R.M.T (rRNA, mRNA, and tRNA) G6PD deficiency? 5H's - . HMP shunt enzyme deficiency Hurts RBCs by exposing them to oxidation, which normally is prevented by NADPH Hemoglobin is altered, precipitates Heinz bodies form Hemolytic anemia results

What does the liver do generally during the fasting state? "In the Phasting state, Phosphorylate." Which tissues don't need insulin for glucose uptake? BRICK L: Brain RBCs Intestine Cornea Kidney Liver Pompe's? "Pompe's trashes the Pump" (heart, liver, and muscle) Glycogen storage disease What are the major apolipoproteins and what do they do? A-1 Activates LCAT B-100 Binds to LDL receptor C-II Cofactor for lipoprotein lipase E - mEdiates Extra (remnant) uptake Biotin? AVIDIN in egg whites AVIDly binds biotin Branched chain amino acids "LeVIs" Leucine Valine Isoleucine 'The Rhythmic Notes Proved Contagious': In order: Thiamine (B1) Riboflavin (B2) Niacin (B3) Pyridoxine (B6) Cobalamin (B12) Golgi complex: functions "Google Distributes Ad SPAM": Distributes proteins and lipids from ER Add mannose onto specific lysosome proteins Sulfation of sugars and selected tyrosine Proteoglycan assembly Add O-oligosugars to serine and threnonine Modify N-ologosugars on asparagine