Certificate

The work described in this thesis entitled Characterization and Impurity Profiling of API used as Anti- retro viral Drug has been carried out by Mr. MITUL THEKDI under my supervision. I certify that this is his bonafide work. The work described is original and has not been submitted for any degree to this or any other university.

Date: ________________

Place: Mumbai

Research Guide

Dr. R.S. Gaud

Dean SPP SPTM, Mumbai

Dr. Yogesh Kulkarni

Assistant Professor SPP SPTM, Mumbai

Dr. Bala Prabhakar

Head Industrial Pharmacy Division SPP SPTM, Mumbai

Dr. R. S. Gaud
Dean SPP SPTM, Mumbai

Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management SVKMsNMIMS Vile Parle (W), Mumbai-400056

Acknowledgement
On this solemn occasion of successful completion of my work I offer my sincere adoration to God who created me the strength & courage to complete my dissertation & given me opportunity to thank all those people through whom this grove delivered to me. I would like to bring to light all those who helped me in completion of my research work. A special thanks to SPP School of Pharmacy and Technology Management, SVKMS NMIMS for giving me an opportunity to see my life in proper direction and to complete my work. I am very much thankful my respected research guides Dr.R S. Gaud Dean, Pharm,Science and Dr.Yogesh Kulkarni, Assistant Professor and Dr. P. G. Shotriya as well Dr. Bala Prbhakar, Head of Industrial Pharmacy division and Mrs. Vaishali Londhe, Associate of Industrial Pharmacy for their meticulous guidance and research inputs.. I am extremely thankful to Macleods Pharmaceuticals Ltd., for providing all the facilities and incredible help and support during my project. I am immensely thankful to Mr.Shailesh Gohad, General Manager and Mr.Shridhar Koparkar, Vice President of Macleods Pharmaceuticals Limited, Mumbai for his guidance, direction, support & advice which enabled me to complete this project work. I like to express my sincere thanks to Mr. Abhijeet, Mr. Shripad, Mr. Amol, Mr. Kisan, Dr. Richa, Ms. Swati , Mr.Lakshaman and all other scientists of Macleods Pharmaceuticals for their guidance, suggestions and great helps made during my project work. It is indeed a great privilege to express a deep sense of gratitude towards my family members for their love & support. I am at loss of words while thanking my beloved Parents for their support, Sacrifice & for the pain they have taken

in bringing me up to this position. I express my deepest sense of gratitude in remembering the love received from my brother and bhabhi which has been the driving force behind the progress & success in every step of my life. My acknowledgement is incomplete without a heartfelt thank to all those people who directly or indirectly helped contributed to this thesis in their own way.

- Mitul Thekdi