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Level 3

AN 3008 TISSUE ORGANISATION


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CREDIT POINTS 15

Course Co-ordinator: Dr I Stewart Pre-requisite(s): BI 20B2 or BI 25B2 or BI 20Z1. The course will include lectures on the differentiation of the four primary tissues. Further lectures will examine the way that these tissues combine to form structural and functional units along the themes of Surfaces, Tubes and Structural Support within mammals but with an emphasis on the human situation. Practicals will offer demonstrations of traditional and modern methods of analysing structure with practical experience of the analysis of data produced by such methodologies. 3 one-hour lectures per week; 3 all day practicals/demonstrations; 3 small group tutorials. 1st Attempt: Continuous assessment (30%); 1 two-hour written examination (70%). Resit: Continuous assessment (30%); 1 two-hour written examination (70%). AN 3301

HUMAN EMBRYONIC DEVELOPMENT CREDIT POINTS 15

Course Co-ordinator: Dr A Venkatesh Pre-requisite(s): Level 2: BI 20M1, BI 20B2, or BI 25B2 or BM 2009 / BM 2509 (the latter BSc Biomedical Sciences students only) Co-requisite(s): Normally Core Molecular Technologies for Biologists (BT 3007, 30 credits) - DB students only or Molecules, Membranes and Cells (BM 3006, 30 credits) BMS students only). This course will cover the following topics: 1. Axis determination.

2. Formation of the human blastocyst.

3. Gastrulation.

4. Development of the Germ Layers.

5. The function of the "Node".

6. Determination of the rostro-caudal axis.

7. Determination of the dorso-ventral axis.

8. Neurulation.

9. Development of the circulatory system.

10. The development and role of the Neural crest.

11. Limb development.

12. Differentiation of the muscles and skeleton.

13. Sex determination and the urogenital system.

14. Birth defects. 3 one-hour lectures per week, 2 full day (8 hour) practicals, 3 two-hour tutorial. 1st Attempt: 1-hours written examination (70%); continuous assessment (30%). Resit: 1-hours written examination. AN 3503 BIOLOGICAL IMAGING CREDIT POINTS 15

Course Co-ordinator: Dr I Stewart and Professor M Helfrich

Pre-requisite(s): BM 2009, BM 2509, AM 3008. Note(s): Restricted to BScBMS Anatomy students. Historical overview of biological imaging techniques Light and electron microscopy including specialist preparative techniques Confocal miscroscopy and Image analysis Radiological techniques including ultrasound, MRI, CT and associated specialist preparative techniques PET The application of imaging techniques in cell and organ culture 2 lectures and 2 interpretive tutorials (or additional lectures) per week 4 All day practicals/demonstrations (over six week course) 1st Attempt: One 1-hour written examination (70%); Continuous assessment (30%) In course work to be divided between range of image interpretive exercises (10%), investigate exercise and report (1,000 words), and practical reports (10%). Resit: One 1-hour written examination (70%); Continuous assessment normally carried forward from in-course (30%).

> Level 4

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PLEASE NOTE: Resit: (for Honours students only): Candidates achieving a CAS mark of 6-8 may be awarded compensatory level 1 credit. Candidates achieving a CAS mark of less than 6 will be required to submit themselves for reassessment and should contact the Course Co-ordinator for further details. AN 4002

BRAIN FUNCTION AND MALFUNCTION CREDIT POINTS 15

Course Co-ordinator: Dr B Platt Pre-requisite(s): BM 3006. Note(s): The practical work required in this course may pose difficulties to students with disabilities. For such students, alternate arrangements will be made. Any student wishing to discuss this further should contact the School Disability Co-ordinator. There is currently much interest in the organisation and function of the mammalian brain. The way in which neuronal pathways interact to produce given behaviours, emotions and desires, and capabilities such as sensation and awareness represents one of the hallmarks of todays research. Topics such as these are introduced in lectures on neuroanatomy and expanded upon by seminar presentations. An additional focus is malfunctions of the central nervous systems (CNS), such as Alzheimers disease or stroke.

6 weeks course, Thread I 10 one-hour lectures, 3 four-hour practicals and 6 one-hour seminars. 1st Attempt: 1 two-hour written examination (80%) and seminar presentation (20%). AN 4003 BRAIN FUNCTION AND MALFUNCTION (WITH ANATOMY) CREDIT POINTS 15 Course Co-ordinator: Dr I J Stewart (with Dr B Platt) Pre-requisite(s): Acceptance into honours year of BScBMS (Anatomy) degree. Note(s): Students taking this course may not register for AN 4002. There is currently much interest in the organisation and function of the mammalian brain. The way in which neuronal pathways interact to produce given behaviours, emotions and desires, and capabilities such as sensation and awareness represents one of the hallmarks of today's research. Topics such as these are introduced in lectures on neuroanatomy and expanded upon by seminar presentations. An additional focus is malfunctions of the central nervous systems (CNS), such as Alzheimer's disease or stroke. In addition, there will be a structured dissection based instructional practical course providing the skills necessary to define peripheral nerves and other tissues. 6 two-hour lectures; 2 two-hour seminars; 2 three-hour practical classes; 4 two-hour dissection classes. Attendance at departmental seminars encouraged. 1st Attempt: 1 two-hour written examination (80%) and dissection activity report (20%). Resit: Not normally available. AN 4301 DEVELOPMENTAL NEUROSCIENCE (WITH ANATOMY) CREDIT POINTS 15 Course Co-ordinator: Dr A Venkatesh (with Dr A Rajnicek) Pre-requisite(s): Acceptance into honours year of BScBMS (Anatomy) degree. Note(s): Students taking this course may not register for PY 4302. This course considers the development of the nervous system in a broad context and aspects of its plasticity when mature and its regenerative capacity when damaged. Topics include the establishment of a nervous system in the embryo, birth and migration of nerve cells, nerve growth and guidance mechanisms, cell recognition, cell death, synaptogenesis, development of the eye and the use of stem cells in regeneration. Neural plasticity and interactions with the environment are examined by reviewing the development of mammalian sensory systems over a critical period. Plasticity in the adult nervous system covers aspects of learning and memory, central and peripheral nerve and muscle regeneration following injury and some examples of disease states (eg. metabolic neuropathies and myopathies, muscular dystrophy, ageing and dementia).

In addition, there will be an elective dissection based activity, based on an aspect of the central or peripheral nervous system to enhance human cadaveric dissection skills and illustration. 18 lectures, student led seminar sessions, 4 two-hour dissection classes (to be arranged). Attendance at departmental seminars encouraged. 1st Attempt: 1 two-hour written examination (75%), in-course seminar report (10%) and dissection activity and illustrative report (15%).

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