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A REVOLUTION IN FUNCTIONAL T CELL ANALYSIS Frustrated with current T cell assays? Take control with a single assay that gives you all the information you need. Discover which individual T cells express FOXP3, TNF-, or other effector geneswithout staining or cell sorting. Starting with a single-cell suspension, GigaMune TELS (TCR-Effector Linkage Sequencing) uses unique microfluidics and molecular techniques to physically link T cell variable regions to effector genes expressed within millions of individual T cells in a sample. By sequencing TCR-effector linkage products, GigaMune TELS gives you simultaneous, quantitative measurements of T cell clonal identity and effector gene activity. Never has a single assay combined accurate measures of T cell identity, clonality, expansion, and function. Let GigaMune TELS revolutionize your understanding of the T cell response.
IMMUNOPHENOTYPING APPLICATIONS
Autoimmune diseases Transplant rejection and tolerance Immune response to malignancy Cancer immunotherapy Adoptive T cell therapy Asthma and allergy Inflammatory conditions Infectious diseases Vaccine development and efficacy Global immune function and health
HIGHLIGHTS
FEATURES Millions of single cells processed per hour Massively parallel amplification of transcripts produced by single cells Multiplexed measurements of TCR CDR3 sequence and effector gene transcripts High-quality sequence of TCR CDR3 regions Accurate measurements of clonal abundance Powerful web-based software suite for data storage, processing, and analysis in the cloud GigaGen laboratory and professional services BENEFITS Detect rare and ultra-rare T cell clones from peripheral blood Classify T cells based on expression of functional effector genes such as transcription factors Learn clonal identity, abundance, and function from the same sample Quantify and distinguish multiple clonotypes with specific effector functions Make objective, quantitative comparisons of clonal expansion across samples Track abundance and expression profiles of clones across samples, with statistical analysis Get reproducible results quickly with no startup costs or training time required
GigaMune TELS is For Research Use Only. Not for use in diagnostic procedures.
TCR FOXP3
Analyze results.
View data using ClonoByte web-based software for data storage, processing, statistical analysis, sample comparison, and data visualization in the cloud.
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