Laboratory Services Group Therapeutic Drug Monitoring Collection Chart

DRUG
Acetaminophen Amikacin

PEAK
1st Sample: 4-6 hrs post ingestion 2nd Sample: 3-4 hrs after 1st sample If IV infusion is 30 min-30 min after IV If IV infusion is 60 min. immediately If IM injection 60 min. after injection 3 hours after dose

TROUGH
Immediately before next dose

Carbamazepine (Tegretol)

Digoxin Gentamycin If IV infusion is 30 min. 30 min after IV If IV infusion is 60 min.- immediately If IM injection 60 min. after injection 6-12 hrs after last dose 4-12 hours after dose 2-4 hours after IV loading dose If PO: 75 min after dose If IV treatment: immediately after lead dosage 2, 6, 12, 24. After starting dosage steady state levels must be obtained. If IV: 4-6 hrs after constant dose established If PO: 8-10 hrs after last dose If IV infusion is 30 min. 30 min after IV If IV infusion is 60 min. immediately If IM injection 60 min after injection If IM injection 60 min after injection If 60 min infusion 120 minutes after IV infusion.

Immediately before next dose or 8 hours after the dose up to the next dose Immediately before next dose or at least 6 hours after dose Immediately before next dose

Lithium Phenobarbital Phenytoin (Dilantin) Procanimide

Immediately before next dose or at least 12 hours after dose Immediately before next dose Immediately before next dose or 8 hours after the dose. Immediately before next dose

Theophylline Tobramycin

Immediately before next dose Immediately before next dose

Vancomycin Valporic Acid

Immediately before next dose Immediately before next dose or 8 hours after the dose up to the next dose.

NOTE: All Routine TDMs are collection based on the rough draw time unless ordered otherwise by the physician. Last dose time will be reported out on all TDMs. Therapeutic reference range is the trough range except for antibiotic peak tests.

I:\Clients\Lab Services Inc\web\site\public\TDM Collection Chart.doc

Last printed 7/22/2009 12:54 PM

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