GNIPST BULLETIN 2013

1118-1177-4796-9849-7562-5062

TO GROW AS A CENTRE OF EXCELLENCE IN THE FIELD OF PHARMACEUTICAL AND BIOLOGICAL SCIENCE

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8th March 2013

Volume No.: 23

Issue No.: 02

Vision

Contents

Message from GNIPST Letter to the Editor News Update Disease Outbreak News Health Awareness Forth Coming Events Drugs Update GNIPST Photo Gallery
For your comments/contributionOR For Back-Issues, mailto:gnipstbulletin@gmail.com

Campus News Students Section Editors Note Archive

1 EDITOR: Debabrata Ghosh Dastidar

GURU NANAK INSTITUTE OF PHARMACEUTICAL SCIENCE AND TECHNOLOGY

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MESSAGE FROM GNIPST

All the members of GNIPST are proud to publish the 23rd Volume of GNIPST BULLETIN. This bulletin has successfully completed its twenty months journey. We hope it has kept the readers updated of recent activities in pharmaceutical & biological sciences and also introduced them with the different activities of our esteemed institution. We are thankful to all of you for your great cooperation & support and are looking forward to the same in future.

LETTER TO THE EDITOR.

NEWS UPDATE

Pour, Shake and Stir: How Gold Particles, DNA and Water Have the Potential to Shape the Future of Medicine (28 FEBRUARY 2013)
A diagnostic "cocktail" containing a single drop of blood, a dribble of water, and a dose of DNA powder with gold particles could mean rapid diagnosis and treatment of the world's leading diseases in the near future. Read more

Ultrasound to Detect Lung Congestion in Dialysis Patients May Help Save Lives (28
FEBRUARY 2013)

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Lung ultrasound can detect asymptomatic lung congestion in dialysis patients and can predict their risk of dying prematurely or experiencing heart attacks or other cardiac events. Treating asymptomatic lung congestion may help improve cardiovascular health and prevent cardiovascular deaths in dialysis patients. Lung congestion is highly prevalent and often asymptomatic among patients with kidney failure. Read more

Machine Similar to Dialysis Removes Cholesterol from Blood? (28

FEBRUARY 2013)

A treatment that's similar to kidney dialysis is removing cholesterol from the blood of patients who cannot control cholesterol through diet, exercise and medications. Read more Excess Dietary Salt May Drive the Development

of Autoimmune Diseases (06

MARCH 2013)

Increased dietary salt intake can induce a group of aggressive immune cells that are involved in triggering and sustaining autoimmune diseases. In autoimmune diseases, the immune system attacks healthy tissue instead of fighting pathogens. In autoimmune diseases, the immune system attacks healthy tissue instead of fighting pathogens. Read more

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Nanoparticles Loaded With Bee Venom Kill HIV

(07

MARCH 2013)

Nanoparticles carrying a toxin found in bee venom can destroy human immunodeficiency virus (HIV) while leaving surrounding cells unharmed, researchers have shown. The finding is an important step toward developing a vaginal gel that may prevent the spread of HIV, the virus that causes AIDS. Read more

HEALTH AWARENESS
MISUSE AND OVERUSE OF INJECTION WORLDWIDE

Injection is one of the most common health care procedures. Each year at least 16 billion injections are administered in developing and transitional countries. The vast majority, around 95%, are given in curative care. Immunization accounts for around 3% of all injections, with the remainder for other indications, including use of injections for transfusion of blood and blood products and contraceptives. In certain regions of the world, use of injections has completely overtaken the real need, reaching proportions no longer based on rational medical practice. In some situations, as many as nine out of ten patients presenting to a primary healthcare provider
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receive an injection, over 70% of which are unnecessary or could be given in an oral formulation. Patients tend to prefer injections because they believe them to be stronger and faster medications. They also believe that doctors regard injections to be the best treatment. In turn, doctors overprescribe injections because they believe that this best satisfies patients, even though patients are often open to alternatives. In addition, prescription of an injection sometimes allows the charging of a higher fee for service. Better communication between patients and providers can clarify these types of misunderstandings and help to reduce injection overuse.

UNSAFE INJECTION PRACTICES: A PLAGUE OF MANY HEALTH SYSTEMS

A safe injection does no harm. However, when safety control practices are not respected, severe infections can result, putting human lives at risk. Reuse of syringes and needles in the absence of sterilization exposes millions of people to infections. Assessments carried out in numerous countries have revealed that syringes and needles are often just rinsed in a pot of tepid water between injections.
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Worldwide, up to 40% of injections are given with syringes and needles reused without sterilization and in some countries this proportion is as high as 70%. Other unsafe practices, such as poor collection and disposal of dirty injection equipment, expose healthcare workers and the community to the risk of needle stick injuries. In some countries unsafe disposal can lead to re-sale of used equipment on the black market. The proportion of non-industrialized countries still reporting that they use open burning of syringes (considered unacceptable by WHO) was 50% in 2004. BURDEN OF DISEASE ASSOCIATED WITH UNSAFE INJECTION PRACTICES The most recent study* indicates that each year unsafe injections cause an estimated 1.3 million early deaths, a loss of 26 million years of life, and an annual burden of USD 535 million in direct medical costs. Unsafe injection practices are a powerful engine to transmit blood-borne pathogens, including hepatitis B virus (HBV), hepatitis C virus (HCV) and human immunodeficiency virus (HIV). Because infection with these viruses initially presents no

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symptoms, it is a silent epidemic. However, the consequences of this are increasingly recognized. Hepatitis B virus: HBV is highly infectious and causes the highest number of infections: in developing and transitional countries 21.7 million people become infected each year, representing 33% of new HBV infections worldwide Hepatitis C virus: Unsafe injections are the most common cause of HCV infection in developing and transitional countries, causing two million new infections each year and accounting for 42% of cases. Human immunodeficiency virus: Globally nearly 2% of all new HIV infections are caused by unsafe injections. In South Asia up to 9% of new cases may be caused in this way. Such proportions can no longer be ignored. HBV, HCV, and HIV cause chronic infections that lead to disease, disability and death a number of years after the unsafe injection. Those infected with hepatitis B virus in childhood will typically present with chronic liver disease by the age of 30 years, at the prime of their life. This has a dramatic effect on national economies.

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*The cost of unsafe injections by M.A. Miller & E. Pisani: Bulletin of the World Health Organization, Vol. 77, no 10, 808811. SAFE AND APPROPRIATE USE OF INJECTIONS IS WITHIN OUR GRASP Unsafe injection practices are often viewed as a chronic problem with no easy solution. However, safe and appropriate use of injections can be achieved by adopting a three part strategy: (1) Changing behaviour of health care workers and patients Twenty years into the HIV pandemic, knowledge of HIV among patients and health care workers in some countries has driven consumer demand for safe injection equipment and irreversibly improved injection practices. With growing knowledge of HCV and HBV, similar patterns of consumer demand for safe injections should emerge. HIV prevention programmes can be expanded to include injection safety components. (2) Ensuring availability of equipment and supplies Simply increasing the availability of safe injection equipment can stimulate demand and improve practices. Because the cost of safe
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disposable syringes is low (less than 5 US cents per unit) when compared to the fee paid for receiving an injection (50 US cents on average), patients are usually willing to pay a little extra for safety once they personalize the risks. (3) Managing waste safely and appropriately As waste disposal is frequently not an integral part of health planning, unsafe waste management is common. However, when it is appropriately planned, significant results ensue. National health care waste management strategies require a national policy to manage health care waste, a comprehensive system for implementation, improved awareness and training of health workers at all levels, as well as the selection of appropriate options for the local solutions.

DISEASE OUTBREAK NEWS

FORTHCOMING EVENTS
AICTE sponsored National Seminar on Recent Advances in the development of Natural Antioxidant

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Date: 12 March 2013 13 March 2013, Venue: Department of Food Technology, Guru Nanak Institute of Technology, 157/F, Nilgunj Road, Panihati, Kolkata-700 114 Details.

DRUGS UPDATES
FDA

approves

Stivarga

for

advanced
FEBRUARY 2013)

gastrointestinal stromal tumors (25

The U.S. FDA expanded the approved use of Stivarga (regorafenib) to treat patients with advanced gastrointestinal stromal tumors (GIST) that cannot be surgically removed and no longer respond to other FDA-approved treatments for this disease. Read more

FDA women (26

approves

Osphena

for pain

postmenopausal during sex

experiencing

FEBRUARY 2013)

The U.S. FDA approved Osphena (ospemifene) to treat women experiencing moderate to severe dyspareunia (pain during sexual intercourse), a symptom of vulvar and vaginal atrophy due to menopause. Read more

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CAMPUS NEWS

STUDENTS SECTION
WHO CAN ANS WER FIRS T???

() Which is the first patented organism in the world? () August Dvorak and W. Dealy are associated with invention of which computer device?
Answer of Previous Issue Question:

A) Giraffe

B) Butter

Send your thoughts/ Quiz/Puzzles/games/writeups or any other contributions for Students Section & answers of this Section at EDITORS NOTE I am very happy to publish the 22nd issue of 23rd Volume of GNIPST BULLETIN. It is my great pleasure to introduce you to the newly launched facebook account GNIPST bulletin. You are cordially
gnipstbulletin@gmail.com

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invited to add this account to your friend list. The current issues will also be directly available on facebook. I would like to convey my thanks to all the GNIPST members and the readers for their valuable comments, encouragement& supports. Special thanks to Dr. Prerona Saha for her advice; Mr. Soumya Bhattacharya, for his contribution in students section. It would be my great pleasure to receive the contributions, suggestions & feedback from your desk for further upliftment of this deliberation GNIPST BULLETIN.

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ARCHIVE The general body meeting of APTI, Bengal Branch has been conducted at GNIPST on 15th June, 2012. The programme started with a nice presentation by Dr. Pulok Kr. Mukherjee, School of Natural Products, JU on the skill to write a good manuscript for publication in impact journals. It was followed by nearly two hour long discussion among more than thirty participants on different aspects of pharmacy education. Five nonmember participants applied for membership on that very day. GNIPST is now approved by AICTE and affiliated to WBUT for conducting the two years post graduate course (M.Pharm) in

PHARMACOLOGY. The approved number of seat is 18.

The number of seats in B.Pharm. has been increased from 60 to 120. 2nd World Congress on Ga-68 (Generators and Novel Radiopharmaceuticals), Molecular Imaging (PET/CT), Targeted Radionuclide Therapy, and Dosimetry (SWC-2013) : On the Way to Personalized Medicine

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Dates 28 Feb 2013 02 Mar 2013 Location: Chandigarh, India.Details.

AICTE has sanctioned a release of grant under Research Promotion Scheme (RPS) during the financial year 201213to GNIPST as per the details below: a. Beneficiary Institution: Guru Nanak Institution of Pharmaceutical Science & Technology. b. Principal Investigator: Dr. LopamudraDutta. c. Grant-in-aid sanctioned:Rs. 16,25000/- only d. Approved duration: 3 years e. Title of the project: Screening and identification of potential medicinal plant of Purulia&Bankuradistricts of West Bengal with respect to diseases such as diabetes, rheumatism, Jaundice, hypertension and developing biotechnological tools for enhancing bioactive molecules in these plant.

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