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Path Lab Exam I Tally of Tagged Items: Acute appendicitis (pt had nausea, vomiting, fever, and acute

e abd pain) Microscope slide 3 Once, asked for additional lab findings of appendicitis answer was increased total WBCs w/neutrophils and band forms present Acute glomerulonephritis Kidney biopsy, photos 3 Adenomatous polyp (after segmented colon resection) 2 AFP Monitor tumors for recurrence during chemo using 1 AIDS prevalence Graph 1 Alkaline Phosphatase, bilirubin The changes in gall bladder suggest 2 Anaplastic tumor (twice, choose the best descr. for this neoplasm) Two H&E-stained slides 3 Anthracosis and squamous cell carcinoma. Once: long time smoker, resection of left upper lobe of lung after fine needle biopsy. 2 Once, smoker underwent thoracotomy and removal of right lung for malignant tumor diagnosed by FNA, 5.0cm diameter. Answer was Lung, squamous cell carcinoma; lymph nodes, anthracosis Aorta w/atherosclerosis (twice, was atherosclerosis + thrombus) 3 Apoptosis Photos 1 Asthma (ON FOUR TESTS, the patient dies in the ER) Lung biopsy 5 Atrophy (kidney) 3 Auspitz sign Skin changes shown in photo what would be a finding? 2 Basal cell carcinoma Biopsy from nose/hand/ear, photos/microscopic images 5 Bilateral leg fractures The gross path in this specimen is consistent with a 3 history of (pulmonary embolus is shown) Bile stasis (once, clues were reformed alcoholic, abd pain + jaundice) Liver biopsies 6 Bronchopneumonia Lung photo 1 Bullae (lung) Gross 4 Candida albicans Tongue, Gram stain, germ tube test 1 Carcinoma in-situ (CIS) Diagram 2 Caseous granuloma (or caseous necrosis, caseation necrosis) H&E biopsy 6 Chronic inflammation and calcification of kidney 1 Cirrhosis 4 Cirrhosis, carcinoma, and necrosis Autopsy liver biopsy 1 Cirrhosis, infarction, and hepatocellular carcinoma (pt was jaundice) Liver biopsy 2 Coagulative necrosis (Once was lung; spleen 3 times. Once, pt had angioplasty after MI and was on anti-HT drugs) Photos 7 Congestion, edema, and pneumonia (75 y/o died 6 mo after MI) Lung biopsy 1 Cushing syndrome Lung biopsy tumor 1 Cysts (once specified kidney) 3 Dermatitis herpetiformis H&E skin biopsy, IgA stain, gross 2 Diabetes Mellitus Type 1 Photos 1 Diabetic lesions Type I and Type II Pancreas biopsies 3 Dystrophic calcification of the aorta 1 Endocarditis 2 Enzymic fat necrosis Photos, pancreas 2 Fatty change (3 times, was fatty change w/o cirrhosis) Liver biopsy 4 Fibroadenoma H&E-stained breast biopsy 2 Glandular metaplasia region (must classify A/B/C or D as this) Barretts syndome surgical specimen photo 3 Granuloma Gross photo and microscopic image 1 Granulomatous inflammation (supraclavicular lymph node) Patient w/gastric carcinoma and cavitary lung nodules 1 Hashimoto disease (aka Hashimotos thyroiditis) H&E-stained thyroid biopsy 3 Hemochromatosis (liver) Twice, said both organs are consistent with 5 Histoplasma capsulatum Giemsa and GMS (silver) stained bronchoalveolar lavage 1 (BAL) HPV Cytology (Pap smear) 2 Hyperplasia (adrenal) Photo 1 Hyperplasia (prostate) Biopsy 1 Hyperplasia and carcinoma (prostate) Photos 1 Hypertrophy (once- specifically heart) 2 Hypertrophy, smooth muscle (prostate + bladder) 1 Hypertrophy (prostate) + hyperplasia (bladder) 1 Hypertrophy (bladder) + hyperplasia (prostate) 3 Infarction Which of the photographs is consistent w/infarction? 1 Invasive adenocarcinoma Stomach biopsy 1 Invasive ductal carcinoma Small (<5cm) breast mass biopsy 1 Kaposis sarcoma and candidiasis This AIDS patient exhibits oral lesions consistent with... 1 Langerhans cell histiocytosis Electron microscope images 2 Leiomyoma (uterine mass/tumor) 3 Lobar pneumonia Describe the appearance of this lung 1 Lung cancer Graph 1 Lymphocytes/plasma cells in the stroma and neutrophils in the ducts Best description for the inflammatory infiltrate (in a 1 prostate biopsy) Malignant vs benign Once, tissue was unspecified. Once, was breast tissue. (answer: A is malignant, B is benign) Photos 2

Melanoma (Once- pigmented mole, size of pencil eraser. Once- irreg, pigmented lesion, 13mm diameter) Photos, biopsy 4 Meningioma 2 Merkel cell tumor, foreign body giant cell reaction and fibrosis Slide showing re-excision of the tumor 1 Metastates (liver) 1 Metastatic calcification (clues: benign adenoma adj to thyroid was removed 5 years ago, has bone irregularities) Lung biopsy 1 Metastatic carcinoma (liver) 4 Metastatic Melanoma (twice in brain, once in ovary+bone) Photo 3 MI Day #7 Photo of myocardium 3 Multiple myeloma (pt suffered from constrictive cardiomyopathy, renal failure, and coagulopathy) Liver biopsy 1 Neuroblastoma Abdomen tumor, kidney, & adrenal gland removed 1 OraQuick HIV-1 is: a screening test for HIV-1 1 Osteoblastic bone lesions Prostate photo this disease assocd with 2 Pancreatic cancer (Pt had increased scleral and skin pigmentation and abnormal liver fxn tests. Underwent ultrasound-guided 1 liver biopsy) Pemphigus vulgaris H&E skin biopsy, IgG stain 5 (Bullous skin lesion given as clue once. Once, pt had painful oral ulcers and blisters on her back blister was biopsied) Pneumocystis Photos 2 Pneumocystis jiroveci H&E stain, GMS (silver) stained bronchoalveolar lavage 1 (BAL) Polycystic kidney 1 Polycythemia This tumor/neoplasm (in kidney) is consistent with 2 Polyps (colon) 1 Portal hypertension treatment Both photos illustrate treament of 1 Post-mortem clot Slide (from pulmonary artery at autopsy) 2 Psoriasis Clinical photos, H&E skin biopsy 1 Pulmonary embolus 1 Renal cell carcinoma Kidney biopsy 1 Rheumatic heart disease (Patient presents w/heart failure) Illustrations, twice was heart biopsy (Aschoff bodies shown) 4 Right heart failure Gross photo, H&E section of liver (once) 4 Signet ring cell adenocarcinoma (twice was stomach tumor, malignant) H&E biopsies 3 Once, answer was lung, metastatic adenocarcinoma, signet ring type Small cell undifferentiated carcinoma Lung biopsy 1 Squamous cell carcinoma (once, answer was invasive SCC) Lung biopsy, larynx biopsy, bronchus biopsy 4 Systemic Lupus Erythematosis (choose the ANA fluorescence pattern most consistent w/SLE) 1 Teratoma Photos of resected ovary 1 Thrombosis (once in lung, once in aorta) 2 Thrombus (once, aorta was specified) Gross image, microscopic image 5 Tuberculosis Lymph node biopsy from patient w/lung nodules 2 Ulcer (once- specifically stomach) Gross photos, microscopic image 5 Undifferentiated tumor Best description for this neoplasm 2 Verruca vulgaris (Grossly resembled a cauliflower once. Once, hard solitary papule w/rough surface on hand.) Skin biopsy 4 WT-1 (Tumor removed from kidney/adrenal area. What gene/protooncogene is commonly associated w/this tumor?) 1

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