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  • Oral Antihypertensive Drugs : Class Drug (Trade Name) Usual Dose Range in Mg/day Usual Daily Frequency

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    Satish Veerla
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    This document provides information on common oral antihypertensive drug classes, including thiazide diuretics, loop diuretics, potassium-sparing diuretics, beta blockers, ACE inhibitors, angiotensin II antagonists, calcium channel blockers, alpha blockers, central alpha-2 agonists, and direct vasodilators. It lists example brand and generic drugs in each class along with their usual daily dose ranges and administration frequencies. The document is intended as a reference for pharmacologic treatments for hypertension based on drug class and individual medications.

    Исходное описание:

    overview of antihypertensive drugs

    Оригинальное название

    19 Oral Antihypertens Drugs

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    This document provides information on common oral antihypertensive drug classes, including thiazide diuretics, loop diuretics, potassium-sparing diuretics, beta blockers, ACE inhibitors, angiotensin II antagonists, calcium channel blockers, alpha blockers, central alpha-2 agonists, and direct vasodilators. It lists example brand and generic drugs in each class along with their usual daily dose ranges and administration frequencies. The document is intended as a reference for pharmacologic treatments for hypertension based on drug class and individual medications.

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    62 просмотров3 страницы

    Oral Antihypertensive Drugs : Class Drug (Trade Name) Usual Dose Range in Mg/day Usual Daily Frequency

    Загружено:

    Satish Veerla
    This document provides information on common oral antihypertensive drug classes, including thiazide diuretics, loop diuretics, potassium-sparing diuretics, beta blockers, ACE inhibitors, angiotensin II antagonists, calcium channel blockers, alpha blockers, central alpha-2 agonists, and direct vasodilators. It lists example brand and generic drugs in each class along with their usual daily dose ranges and administration frequencies. The document is intended as a reference for pharmacologic treatments for hypertension based on drug class and individual medications.

    Авторское право:

    Attribution Non-Commercial (BY-NC)
    Скачайте в формате PDF, TXT или читайте онлайн в Scribd
    Отметить как неприемлемый контент
    из 3

    Pharmacologic Treatments: Oral antihypertensive drugs

    Oral antihypertensive drugs*


    Class
    Thiazide diuretics

    Drug (Trade Name)


    Chlorothiazide (Diuril) chlorthalidone (generic) hydrochlorothiazide (Microzide, HydroDIURIL) polythiazide (Renese) indapamide (Lozol) metolazone (Mykrox) metolazone (Zaroxolyn)

    Usual dose range in mg/day


    125-500 12.5-25 12.5-50 2-4 1.25-2.5 0.5-1.0 2.5-5 0.5-2 20-80 2.5-10 5-10 50-100 50-100 25-50 25-100 5-20 2.5-10 50-100 50-100 40-120 40-160 60-180 20-40 200-800 10-40 10-40 12.5-50 200-800

    Usual Daily Frequency


    1-2 1 1 1 1 1 1 2 2 1 1-2 1-2 1 1 1 1 1 1-2 1 1 2 1 2 2 1 2 2 2
    1

    Loop diuretics

    bumetanide (Bumex) furosemide (Lasix) torsemide (Demadex)

    Potassium-sparing diuretics Aldosterone receptor blockers BBs

    amiloride (Midamor) triamterene (Dyrenium) eplerenone (Inspra) spironolactone (Aldactone) atenolol (Tenormin) betaxolol (Kerlone) bisoprolol (Zebeta) metoprolol (Lopressor) metoprolol extended release (Toprol XL) nadolol (Corgard) propranolol (Inderal) propranolol long-acting (Inderal LA) timolol (Blocadren)

    BBs with intrinsic sympathomimetic activity

    acebutolol (Sectral) penbutolol (Levatol) pindolol (generic) carvedilol (Coreg) labetalol (Normodyne, Trandate)

    Combined alpha- and BBs

    Pharmacologic Treatments: Oral antihypertensive drugs

    Oral antihypertensive drugs* (continued)


    Class
    ACEIs

    Drug (Trade Name)


    benazepril (Lotensin) captopril (Capoten) enalapril (Vasotec) fosinopril (Monopril) lisinopril (Prinivil, Zestril) moexipril (Univasc) perindopril (Aceon) quinapril (Accupril) ramipril (Altace) trandolapril (Mavik)

    Usual dose range in mg/day


    10-40 25-100 5-40 10-40 10-40 7.5-30 4-8 10-80 2.5-20 1-4 8-32 400-800 150-300 25-100 20-40 20-80 80-320 180-420 120-540 80-320 120-480 120-360 2.5-10 2.5-20 2.5-10 60-120 30-60 10-40

    Usual Daily Frequency


    1 2 1-2 1 1 1 1 1 1 1 1 1-2 1 1-2 1 1 1-2 1 1 2 1-2 1 1 1 2 2 1 1
    2

    Angiotensin II antagonists

    candesartan (Atacand) eprosartan (Teveten) irbesartan (Avapro) losartan (Cozaar) olmesartan (Benicar) telmisartan (Micardis) valsartan (Diovan)

    CCBsnonDihydropyridines

    Diltiazem extended release (Cardizem CD, Dilacor XR, Tiazac) diltiazem extended release (Cardizem LA) verapamil immediate release (Calan, Isoptin) verapamil long acting (Calan SR, Isoptin SR) verapamilCoer, Covera HS, Verelan PM)

    CCBsDihydropyridines

    amlodipine (Norvasc) felodipine (Plendil) isradipine (Dynacirc CR) nicardipine sustained release (Cardene SR)
    nifedipine long-acting (Adalat CC, Procardia XL)

    nisoldipine (Sular)

    Pharmacologic Treatments: Oral antihypertensive drugs

    Oral antihypertensive drugs* (continued)


    Class
    Alpha-1 blockers

    Drug (Trade Name)


    doxazosin (Cardura) prazosin (Minipress) terazosin (Hytrin)

    Usual dose range in mg/day


    1-16 2-20 1-20 0.1-0.8 0.1-0.3 250-1,000 0.1-0.25 0.5-2 25-100 2.5-80

    Usual Daily Frequency


    1 2-3 1-2 2 1 wkly 2 1 1 2 1-2

    Central alpha-2 agonists and other centrally acting drugs

    clonidine (Catapres) clonidine patch (Catapres-TTS) methyldopa (Aldomet) reserpine (generic) guanfacine (Tenex)

    Direct vasodilators

    hydralazine (Apresoline) minoxidil (Loniten)

    * In some patients treated once daily, the antihypertensive effect may diminish toward the end of the dosing interval (trough effect). BP should be measured just prior to dosing to determine if satisfactory BP control is obtained. Accordingly, an increase in dosage or frequency may need to be considered. These dosages may vary from those listed in the Physicians Desk Reference, 57th ed. Available now or soon to become available in generic preparations. Source: Physicians' Desk Reference. 57 ed. Montvale, NJ: Thomson PDR, 2003 Source: JNC 7

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