Section 6 QMU

Health care 1. All of the following statements are true about exogenous sources of Health CareAssociated Infection except A. Contaminated objects B. Occurs after acquiring organisms from other patients C. Autoinfection of normal flora D. Occurs after acquiring organisms from environmental sources 2. Which of the following statements are true method of transmission of Health CareAssociated infection A. Ingestion of contaminated food B. Through droplets nuclei carried in air C. Parentral through blood D. All of the above 3. Sterilization is a process usually involving detergent that removes foreign material from an object A. True B. False 4. Choose the correct answer about decontamination A. Any process , chemical or physical that destroys pathogen such that an item is safe to handle for its intended use B. Method that remove or destroy all form of microbial life C. Accomplished principally by steam under pressure D. The use of physical or chemical means to remove, inactivate or destroy pathogen on a surface where they are no longer capable of transmitting infectious particles 5. Use detergents and follow by disinfectants for critical units A. True B. False Answer : c,d, b, d,a

13/5/2013 Parasitology Echinococcus granulosus, Hyadatid disease and Sparganosis 1. All are true regarding E.granulosus EXCEPT: A. In stools specimen, eggs and gravid segments are usually found. B. Men never be definitive host. C. Infection leads to zoonotic disease. D. Hermaphrodites. 2. A. B. C. D. 3. A. B. C. D. 4. A. B. C. D. 5. A. B. C. D. E. Hydatid cyst: By swallowing eggs of E.granulosus. Classical cyst which has irregular shape. Varies in size. May lead to bone deformity and fracture. Choose the INCORRECT regarding hydatid disease: The commonest site for hydatid disease is liver. Symptoms of hydatid disease may take a long time to develop. Surgical removal is preferred in any site. Stray dogs should be eliminated. All are true about hydatid cyst, EXCEPT: Rupture of hydatid cyst may lead to death. Enlargement of cyst may decrease the function of that organ. Eosinophil count are suggestive. Percussion can be done on affected lungs. Sparganosis: By larval stages of other diphyllobothriid tapeworms. Controlled by avoid eating raw flesh of frogs. Diagnosis by biopsy of infected organs. May cause exophthalmos. Surgical removal must be done in ocular sparganosis.

Answers: 1: A 2: B

3: C 4: D 5: E

LYMPH NODE AND SPLEEN DISORDER All of the following statements are true about the non- Hodgkins lymphoma except A. The usual presentation of NHL is localized or generalized non tender lymphadenopathy B. Waldeyers ring and mesenteric nodes rarely involved C. In 65 % of cases, NHL arises in the tissue of lymph nodes D. More frequent involvement of multiple peripheral lymph nodes Chose the correct answer about the Burkitts lymphoma A. It is mainly found in children and young adults B. Responds well to aggressive chemotherapy and long remission may occur C. Endemic in some parts of Africa but also occurs sporadically in non-endemic areas D. All of the above Which of the following answer is not the etiologic and pathogenetic factor in white cell neoplasia? A. Inherited genetic factors B. Chromosomal translocations and oncogenes C. Viruses and environmental agents D. Bacterial infection Choose the correct answer about the Hodgkins lymphoma A. Non-contiguous spread B. Extra nodal involvement is common C. No systemic manifestations D. Histologically, there are Reed-Steinbergs cells against a background of nonneoplastic inflammatory cells Which of the following is not true about congestive splenomegaly? A. Usually caused by congestive heart failure and portal hypertension B. Not associated with hypersplenism C. There is persistent or chronic congestion of the spleen due to back pressure of the splenic vein D. Microscopically, the capsule is fibrosed and there is subcapsular fibrosiderotic nodules caused by organization of old haemorrhages ANSWER; B D D D B

Pharmacology Antidepressants 1. The following are true regarding depression EXCEPT A. Deficient monoamine transmission in the CNS is the cause of depression according to monoamine theory B. It is treated by increasing monoamine concentration in the synaptic cleft C. SSRI is the most widely used antidepressant followed by TCA D. TCAs have the advantage of -adrenoceptors blockade compared to SSRI 2. The following are true EXCEPT A. Imipramine is used to treat panic disorders B. Obsessive compulsive disorders can be treated by amitriptyline and sertraline C. Fluoxetine is used concomitantly with tranylcypromine in patients with suicidal thoughts D. Usage of TCAs and lithium salts should be monitored closely as they have narrow therapeutic margin 3. The following are false EXCEPT A. Tofranil has been used in control of bed wetting in children through 5-HT receptor blocking action B. TCA toxicity treatments include physostigmine C. Venlafaxine, Bupropion, Tranylcypromine, fluvoxamine and thioxanthenes are used as antidepressants D. Fluoxetine induces a number of significant drug interactions (CYP450 inducer) 4. The following are true EXCEPT A. Serotonin syndrome is a result of concomitant usage of MAOI with SSRI B. Serotonin syndrome is characterized by triad of cognitive, autonomic and somatic manifestations C. Hypertensive cheese reaction is a side effect of long term usage of TCAs D. Fluoxetine is used in a depressed pregnant patient 5. A. B. C. D. The following are true EXCEPT amitriptyline is used with lithium in bipolar depression MAOIs are used in patients with resistant cases of depression Fluvoxamine is used in bulimia Venlafaxine is safer than fluoxetine

D,C,B,C,D

ANTI-PSYCHOTIC DRUGS All the following are neural pathways affected by typical anti-psychotic drugs EXCEPT A. Nigrostriatal pathway B. Mesolimbic-Mesocortical pathway C. Chemoreceptor Trigger Zone D. Tubero-infundibular pathway E. None of the above Which of the following drug must be avoided in psychotic patient with epilepsy? A. Clozapine B. Chlorpromazine C. Haloperidol D. Fluphenazine Sedation and confusion as side effects could be attained by blocking which of the following receptor? A. 1- adrenergic receptor B. 5-HT2A receptor C. H1 receptor D. D2 receptor All the following are actions that could be taken to overcome Tardive dyskenesia due to prolonged use of typical antipsychotic drugs EXCEPT A. Reduce the doses B. Replace them with newer atypical antipsychotic drugs C. Use diazepam D. Change oral drug to parenteral drug. A schizophrenic patient presented with social withdrawal symptom, flat effect, amotivation and poverty of speech. Which drug would you prefer to give to the patient? A. Thiothixine B. Risperidone C. Droperidol D. Fentanyl

Answers: E A C D B

Microb

Which is true regarding pulmonary anthrax? a) Leads to haemorrhagic pneumonia b) As a result of eating the spores of bacillus anthracis c) Affects the people working at mines d) It is a mild disease with gradual recovery

Which is false regarding control measures of bacillus anthracis? a) disposing animal bodies by burning and lime pits b) use gloves when handling potentially infected animals c) vaccination of people using alum-precipitated toxoid can be used d) antitoxin to bacillus anthracis can be given to infected patients Which is not an antigenic structure of bacillus anthracis? a) Polysaccharide cell wall b) Polypeptide capsule c) Protein toxin d) Coagulase enzyme Which method is used to destroy bacillus anthracis spores while not spoiling the wool it resides in? a) Autoclaving b) Boiling for 30 min c) Soak in 0.25% formaldehyde at 60 degrees d) Incineration e) Soak with detergent Which of the following is the characteristic culture of bacillus anthracis? a) Gives medulla head appearance b) Can be grown on liver extract agar

c) Culture are strictly aerobes d) Can be grown on macconkeys culture medium

Pathology 1. Which of the following is true ? A) Present of germinal center denotes active process B) T lymphocyte originate from paracortical area itself C) Lymph node in chronic irritation is painful D) Reed sternbeg cell only found in Hodgkins lymphoma 2. Hodgkin lymphoma : a) Most commonest type of lymphomas b) Benign condition and does not turn malignant c) Giant cell(RS) are enough for identification of hodkin lymphoma d) Loss normal architecture of lymph node 3. Staging system : a) less equal in importance with histologic typing b) Are the clinical staging c) Must involve systemic manifestation d) Involvement 2 or more lymph nodes right and left sides of diaphragm in stage 3 4. Neoplastic disease of lymph node a) Divided into Hodgkin and Non Hodgkin lymphomas b) Most commonest type is malignant lymphomas c) Highly benign disease d) Reed sternbeg do not arise from mononuclear macrophage in Hodgkin lymphoma 5. Non neoplastic lymphadenopathy : a) Divided into acute specific and chronic lympadenitis b) Sinus histiocytes originate from lymph node substance itself c) Crohns disease is a cause of chronic lymphadenitis d) Acute stage there is pain and chronic no pain Answer: a,d,b,,d,d

1) According to Rye classification, Hodgkins lymphoma is classified microscopically into : a) Lymphocyte predominance b) Lymphocyte rich c) Lymphocyte depletion d) A & B

e) A & c 2) All are true about Hodgkins lymphoma Lymphocytic Depletion EXCEPT : a) The number of Reed-Sternberg cells are abundance b) There is few number of lymphocytes c) It occurs more commonly in young age d) It has a very poor prognosis e) Non all of the above 3) All the statement below is true EXCEPT : a) HL, Lymphocytes rich has good prognosis b) Lymph node is HL are replaced by pale tumor tissue c) HL, Nodular sclerosis is only more common in male d) HL, Lymphocyte Predominance has large numbers of lymphocytes 4) Stage I : involvement of single lymph node or single extralymphatic organ. (TRUE/FALSE) 5) Reed-Sternberg cells may not be found in conditions other than Hodgkins lymphoma. (TRUE/FALSE) 1) e 2) c 3) c 4) TRUE 5) FALSE