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1. Avian Influenza (Bird Flu); Studies Conducted at Nippon Institute for Biological Science, Research Department on Avian Influenza (Bird Flu) Recently Published........................................................................

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Avian Influenza (Bird Flu); Studies Conducted at Nippon Institute for Biological Science, Research Department on Avian Influenza (Bird Flu) Recently Published
Author: Anonymous Publication info: Veterinary Week (Jan 24, 2011): 163. ProQuest document link Abstract: Fresh data on Avian Influenza (Bird Flu) are presented in the report 'Detection of highly pathogenic avian influenza virus infection in vaccinated chicken flocks by monitoring antibodies against non-structural protein 1 (NS1). Full text: 2011 JAN 24 - (VerticalNews.com) -- Fresh data on Avian Influenza (Bird Flu) are presented in the report 'Detection of highly pathogenic avian influenza virus infection in vaccinated chicken flocks by monitoring antibodies against non-structural protein 1 (NS1).' "H5 and H7 highly pathogenic avian influenza virus (HPAIV) represent a major global concern in poultries and human health. Avian influenza (AI) vaccines are available but not preferred for field applications, primarily because vaccination interferes with sero-surveillances of AIV infection," scientists in Ome, Japan report. "To overcome the problem, ELISA systems using non-structural protein 1 (NS1) of AIV as antigens (NS1ELISA) have been developed to measure anti-NS1 antibodies that are raised in AIV-infected but not in vaccinated chickens. However, some AI-vaccinated chickens having a weak anti-virus immune response may subsequently be infected with AIV and spread the virus. This raises a concern for the validity of NS1-ELISA to detect AIV infection in previously vaccinated chickens. In this study, we developed NS1-ELISA and assessed its feasibility to detect HPAIV infection in chickens previously immunized with H5 or H7 AI vaccines. The results indicated that the NS1-ELISA could identify HPAIV infection in both unvaccinated and vaccinated chickens at 1 week after infection in correlation with results from time-consuming virus isolation tests," wrote N. Takeyama and colleagues, Nippon Institute for Biological Science, Research Department. The researchers concluded: "Taken together, the NS1-ELISA system would be valuable tool to define HPAIV infection when AI vaccine program is in place." Takeyama and colleagues published their study in Veterinary Microbiology (Detection of highly pathogenic avian influenza virus infection in vaccinated chicken flocks by monitoring antibodies against non-structural protein 1 (NS1). Veterinary Microbiology, 2011;147(3-4):283-91). For more information, contact N. Takeyama, Nippon Institute for Biological Science, Research Department, 2221-1 Shinmachi 9-chome, Ome, Tokyo 198-0024, Japan. Keywords: City:Ome, Country:Japan, Antibodies, Avian Flu, Avian Influenza, Avian Influenza (Bird Flu), Bird Flu, Blood Proteins, Globulins, Immunoglobulins, Immunology, Veterinary Research, Virology, Viruses. This article was prepared by Veterinary Week editors from staff and other reports. Copyright 2011, Veterinary Week via VerticalNews.com. Subject: Poultry; Birds; Avian flu; Studies Publication title: Veterinary Week First page: 163 Publication year: 2011 Publication date: Jan 24, 2011 Year: 2011

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Publisher: NewsRx Place of publication: Atlanta Country of publication: United States Publication subject: Veterinary Science ISSN: 1944-2777 Source type: Trade Journals Language of publication: English Document type: Expanded Reporting ProQuest document ID: 845413991 Document URL: http://search.proquest.com/docview/845413991?accountid=148614 Copyright: (c)Copyright 2011, Veterinary Week via NewsRx.com Last updated: 2011-06-13

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