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Confirmation of Spectral Jitter: A Measured Shift in the Spectral Distribution of Intense Pulsed Light Systems using a Time-Resolved Spectrometer

during Exposure and Increased Fluence


Caerwyn Ash1, Godfrey Town2, Marc Clement, PhD1 1. School of Medicine, Swansea University, Wales, SA2 8PP 2. Laser Protection Adviser, GCG Healthcare, UK, RH16 2LT

2009

Statement of Disclosure The following potential conflict of interest relationships are germane to my presentation: Salary and test equipment loan: CyDen Ltd., Wales Travel grant: Swansea University, Wales

2009

Background
Clinical differences reported amongst IPL systems despite comparable system parameters Spectral shift / Spectral Jitter first described in 2004

Time-resolved measurement shows a spectral distribution shift in an intense pulsed light system
E Eadie, P Miller, T Goodman, & H Moseley. Lasers in Medical Science 2007

Relevance of the Structure of Time Resolved Spectral Output to Light Tissue Interaction Using Intense Pulsed Light (IPL) C Ash, G Town, P Bjerring Lasers in Surgery and Medicine 2007

Square Pulse

Materials and Methods


Ocean Optics HR2000+ Spectrometer 1ms Time resolved capability (0.35nm resolution) Wavelength points from 300nm to 1000nm in 50nm intervals Spectral distribution plotted with 1ms resolution or pulse number in the case of multiple pulses

Measurements taken with common system parameters


19 systems measured for study

System output grouped into 4 categories Square pulse Free discharge Close pulse stacking Spaced pulse stacking

Results - Square Pulse

Sharp 530nm filter Single pulse 25ms in duration Consistent distribution of wavelengths during pulse duration

Results - Free Discharge

Poorly filtered emission 17% energy below 500nm

Single pulse 18ms in duration


Spectral distribution changes during pulse duration

650nm increase
450, 500, 550, 600, 700nm decrease

Results - Close Pulse Stacking

Sharp 600nm filter


7 pulses stacked closely together, decaying fluence 900, 950nm increase 600, 650, 700nm decrease from first pulse to last

Results - Close Pulse Stacking

Sharp 620nm filter


Unique analogue pulse profile of number of pulses of 1ms separated by 3ms dwell periods. 900, 950nm increase 650, 700nm decrease from first pulse to last

Results - Spaced Pulse Stacking

Sharp 650nm filter


5 pulses spaced apart of short duration high fluence Spectral distribution consistent flashlamp impedance reverses during off time

Results Increasing Fluence


Square Pulse Free Discharge

Conclusions A change in spectral distribution both within a pulse and increasing fluence was verified.
Spectral Shift more prominent with free discharge systems.

May not be clinically significant as fluence dosimetry is a much greater factor. Epilation is unlikely to be effected due to broad melanin absorption.
Spectral shift could effect treatment outcomes. A system could be modelled and implemented, particularly where absorption characteristics vary.

Conclusions

Many IPL systems incorporate high cut off filters to prevent epidermal absorption, thus concealing the decaying effect in the shorter wavelengths of the flashlamp Porphyrin and epidermal absorption possibly effected

Acknowledgments

Swansea University Singleton Park Swansea SA2 8PP Wales, UK www.swan.ac.uk

CyDen Limited Technium Kings Road Swansea UK SA1 8PH www.cyden.co.uk

Thank You

Email: caerwynash@yahoo.co.uk

Prowave 770

Very poorly filtered System 42% below 770nm


Spectral shift shown by the difference 800-900nm and 900-1000nm

Prowave 770

Program A - 4 pulses total 20ms on time

Program B, 6 pulses total 36ms on time

Program C,14 pulses total 100ms on time

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