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IX.

DRUG STUDY: DRUGNAME ACTION DOSAGE INDICATION CONTRAINDICATION ADVERSE REACTION NURSING RESPONSIBILITIES

Generic name: LOSARTAN Brand name: Cozaar

Angiotens in II receptor (type AT1) antagonist acts as a potent vasoconstrictor 50 mg tab/ OD

*Treatment of hypertension; in heart failure and myocardial infarction, it may be used alone or incombination with other antihypertensive agents. *Renal protection in type 2 diabetic patients with proteinuria.

*renal artery stenosis, hyperkalemia, hypersensitivity, anuria, patients who are hypersensitive to other sulfonamide-derived drugs

CNS: Dizziness, insomnia, *Assess patients blood headache. GI: Diarrhea, dyspepsia. Musculoskeletal: Muscle cramps, back or leg pain. Respiratory: Nasal congestion, cough, pressure before starting therapy and regularly and pulse rate. *Obtain baseline liver and renal function before therapy and regularly assess kidney function BUN and creatinine.

Classification: cardiovascular agent; antihypertensive

and primary vasoactive hormone of the renin angiotensin aldosterone system.

upper respiratory infection, *Monitor forpossible adverse sinusitis drug reaction *Assess for hydration status: mucous membranes and skin turgor *Assess patients familys knowledge of Drug therapy.

DRUGNAME

ACTION

DOSAGE

INDICATION

CONTRAINDICATION

ADVERSE REACTION

NURSING RESPONSIBILITIES

Generic name: Amlodipine Brand name: (Norvasc)

Inhibits the movement of calcium ions across the membranes of cardiac and arterial muscle cells; inhibits

10mg/ tab (OD) PO

*Treatment of hypertension

*Contraindicated with allergies to amlodipine, impaired hepatic or renal function, heart block

CNS: fatigue, lethargy

* Administer drug with food or meals if GI upset occurs *Monitor patient carefully *Monitor cardiac rhythm regularly *Report irregular heartbeat, shortness of breath, swelling of hands or feet, dizziness

*Use cautiously with heart failure

Classification: Antihypertensive

transmembrane calcium flow, which

Calcium Channel results in depression of Blocker impulse formation in specialized cardiac pacemaker muscles, slowing the conduction of the cardiac impulse, depression of myocardial contractility and dilation of coronary arteries and arterioles.

DRUGNAME

ACTION

DOSAGE

INDICATION

CONTRAINDICATION

ADVERSE REACTION

NURSING RESPONSIBILITIES

Generic name: citicholine Brand name: (Zynapse)

Citicoline activates the biosynthesis of structural phospholipids in the neuronal membrane,

100mg/ml (TID)

Cerebrovascular *Hypertonia of the Diseases, parasympathetic accelerates the recovery of consciousness and overcoming motor deficit.

Classification: Neurotonics

increases cerebral metabolism and increases the level of various neurotransmitters, including acetylcholine and dopamine. Citicoline has shown neuroprotective effects in situations of hypoxia and ischemia.

Body temperature elevation Restlessness Headaches Nausea and vomiting Diarrhea Low or high blood pressure Tachycardia Sleeping troubles or insomnia Blurred vision Chest pains

Citicoline may be taken with or without food. Take it with or between meals. The supplement should not be taken in the late afternoon or at night because it can cause difficulty sleeping. Contact the physician immediately if allergic reaction such as hives, rash, or itching, swelling in your face or hands, mouth or throat, chest tightness or trouble breathing are experienced. Watch out for hypotensive effects

DRUGNAME

ACTION

DOSAGE

INDICATION

CONTRAINDICATION

ADVERSE REACTION

NURSING RESPONSIBILITIES

Generic name: metoprolol Brand name: (Prolol)

*Exerts mainly beta1adrenergic blocking activity but also blocks beta-2 receptors at high doses. It

50 mg/tab BID

Indicated to hypertension.

* Contraindicated to kidney and liver failure

Classification: Antihypertensive drugs (betablockers)

reversibly and competitively combines with beta-1 adrenergic receptors to block sympathetic nerve impulses, resulting to decreased myocardial contractility, heart rate, cardiac output and myocardial oxygen consumption.

Fatigue Dizziness Headache Bradycardia GI disturbances Skin rashes Sleep disturbances Sweating Abdominal pain Vomiting

Assess patients condition before therapy and regularly thereafter to monitor drug effectiveness Monitor vital signs specially the BP Do not crush or chew tablets Monitor urine output Tell patient to avoid taking OTC products containing alphaadrenergic stimulants (such as nasal decongestans, cold preparations), alcohol, smoking and to limit sodium intake.