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Ototoxicity
Ototoxicity
Digital Hearing Aid
Ototoxicity (oh-tuh-tok-sis-i-tee) is damage to the hearing or balance functions of
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the inner ear caused by drugs or chemicals. The inner ear contains the hearing mechanism, the end organ of the balance mechanism and the vestibulocochlear nerve, which sends hearing and balance information to the brain. Damage to these areas by ototoxic drugs may cause loss of hearing, tinnitus (ringing or noise in the head or ears) and vertigo or sense of imbalance. The extent of ototoxicity varies with the drug, the dose, duration of exposure and other conditions. In some cases, there is full recovery of any acquired hearing loss, tinnitus, or balance disturbance after the drug has been stopped. In other cases, the extent of damage is limited but permanent. An example of limited damage is high-frequency hearing loss, in which damage to the ear makes it difficult to hear high-pitched speech sounds such as s, th, f and sh and other high-pitched sounds such as musical notes or birds chirping. In more rare cases, there may be more wide spread hearing loss. Many drugs can cause ototoxicity. Patients receiving certain treatments known or suspected to have cochleotoxic or vestibulotoxic side effects (such as cisplatin, carboplatin, radiation, loop diuretics, or aminoglycoside antibiotics) may experience hearing loss, tinnitus, and dizziness/vertigo. C ochleotoxic refers to medications that are toxic to the cochlea (the hearing portion of the inner ear) and vestibulotoxic refers to medications that are toxic to the vestibular (balance) portion of the inner ear. Ototoxic medications can affect one or both portions of the inner ear. The rate of ototoxicity is dependent on the drug dosage, whether the medication is given along with other ototoxic treatments, and other individual patient factors. Other drugs and chemicals may also cause ototoxicity. Hundreds of prescription drugs and over the counter medications are recognized as having the potential to be ototoxic and can result in temporary or permanent changes in hearing and balance function. Aspirin overdose can cause ringing in the ears. The antimalarial drugs quinine and chloroquine may also cause ear damage. Among the environmental chemicals that can cause ear damage are: tin, lead, mercury, carbon monoxide and carbon disulfide. This list is not complete, and many other drugs and chemicals, such as industrial solvents, may cause ear problems.
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What Is An Audiologist?
Audiologists are professionals who specialize in the assessment, treatment and prevention of hearing and balance disorders. Our audiologists have a doctorate or masters degree, hold a national C ertificate of C linical C ompetency in Audiology (C C C -A) and are licensed by the State of Wisconsin.
Hearing Preservation
It is important to limit your exposure of hazardous noise levels and wear hearing protection in loud environments. Prolonged exposure to loud sounds (whether you consider it noise or something more pleasant such as music) can worsen the effects of ototoxic drugs. Hearing protection should always be worn in the presence of these loud sounds, however, it is especially important during the entire course of cancer treatment and for at least 12 months after ototoxic therapy, to avoid the combined effects of high volume exposure and ototoxic drug therapy on the inner ear. C ustom-made and disposable ear protection is available through the Audiology Service at Froedtert Hospital.
Additional Audiology Services Provided Hearing Aids and Assistive Listening Devices
Untreated hearing loss can have a negative effect on social interactions, occupational and educational success, and our general quality of life. If the patients hearing loss indicates the need for hearing aids or assistive listening devices, the audiologist will evaluate your options and dispense high-quality devices through our clinic. Even if hearing aids are not used or recommended, there are many other assistive listening devices available for television, telephone, alarm clocks, smoke detectors and other alerting devices.
Vestibular Evaluation
A persons loss of balance can be discouraging and can cause difficulties in performing everyday tasks. The first step in monitoring and treating damage to the vestibular portion of the inner ear is to evaluate the persons balance system. C ommon balance tests provided are Videonystagmography , Rotary Chair and Platform Posturography . Following these evaluations, a referral to an appropriate physician or rehabilitation program will be made. Our facility has an onsite physical therapist that specializes in the treatment of certain types of dizziness and balance impairments.
Contact/Scheduling Information
Froedtert Hospital 3rd Floor 92 Street Area (Formally West C linics) 9200 W. Wisconsin Ave.
Greenway Medical Complex 3365 S. 103rd St., Suite 210 Greenfield, WI 53227 414-955-2600
Please inform the scheduler that your appointment is for ototoxicity. Baseline and follow-up evaluations for ototoxicity are given special scheduling consideration. We will work with the patient to ensure their tests are performed prior to their next scheduled cancer treatment.
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