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    Frontiers
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    Interdisciplinary science has led to multiple ground-breaking discoveries. New technologies have created new avenues in engineering through invention of microelectromechanical systems (mems) these enabling technologies and tools have found niche applications in addressing challenges in global healthcare.

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    Interdisciplinary science has led to multiple ground-breaking discoveries. New technologies have created new avenues in engineering through invention of microelectromechanical systems (mems) these enabling technologies and tools have found niche applications in addressing challenges in global healthcare.

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    18 просмотров1 страница

    TMP 3784

    Загружено:

    Frontiers
    Interdisciplinary science has led to multiple ground-breaking discoveries. New technologies have created new avenues in engineering through invention of microelectromechanical systems (mems) these enabling technologies and tools have found niche applications in addressing challenges in global healthcare.

    Авторское право:

    Attribution Non-Commercial (BY-NC)
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    Biotechnol. J. 2011, 6, 131 DOI 10.1002/biot.201100009 www.biotechnology-journal.

    com

    Editorial: Micro and nanofluidics –


    applications in biotechnology

    A s the boundaries between


    scientific fields fade, innovations
    agnostic technologies.These POC
    challenges exacerbated under
    Utkan Demirci and Hikmet Geckil

    emerge at the grounds of inter- resource-limited settings, with


    disciplinary science. Interdisci- additional obstacles such as
    plinary science has led to multi- unreliable electricity, enforced
    ple ground-breaking discover- portability requirements on de-
    ies: We have been observing vices and readers, and limited
    multiple converging fields lead- space for peripheral devices.
    ing to numerous junctions be- These intermingled clusters of
    tween disciplines, filling the difficult problems complicate
    bandgaps in our understanding the POC device design, and de-
    in life sciences, physical sci- mand design methodologies and
    ences, and engineering. In this practical thinking strategies that
    atmosphere, we have observed reach beyond capabilities of a
    many of the micro- and nano- single field or a single type of ex-
    fabrication challenges, already Utkan Demirci1,2 and
    addressed by semiconductor Hikmet Geckil3*
    “The capability to manipulate
    technologies, to create new av-
    cells and other biological
    enues in engineering through
    moieties in small volumes has 1 Bio-Acoustic-MEMS
    invention of microelectrome- in Medicine (BAMM)
    been impacting various fields Laboratory, Center for Bioengineering,
    chanical systems (MEMs).These
    of science and engineering” Department of Medicine, Brigham and
    new technologies took wider
    Women’s Hospital, Harvard Medical School,
    steps towards applications in Boston, MA, USA
    biology (bio-MEMs) and lab-on- pertise. Hence, these practical 2 Harvard-Massachusetts Institute of

    a-chip devices facilitated with requirements make a strong Technology Health Sciences and Technology,
    microfluidics. The capability to case for the bandgaps to be filled Cambridge, MA, USA
    3 Department of Biology, Inonu University,
    manipulate cells and other bio- with a new era of scientists and
    logical moieties in small vol- engineers. As a result, it has be- Malatya, Turkey
    umes using microfluidics has come increasingly common for
    E-mails: utkan@mit.edu;
    impacted various fields of sci- engineering PhDs to teach and udemirci@rics.bwh.harvard.edu
    ence and engineering. perform research at medical E-mail: hgeckil@inonu.edu.tr
    These enabling technologies schools or MDs to look for strong
    and tools have found unique collaborations in engineering * Currently on sabbatical leave as Fulbright
    niche applications in addressing schools. Fellow at Harvard-MIT Health Sciences and
    Technology
    challenges in global healthcare. In this environment, with
    E-mails: hgeckil@mit.edu;
    For instance, the challenges as- these advancements in science, hgeckil@rics.bwh.harvard.edu
    sociated with delivering health- this special issue has been
    care at the point-of-care (POC) brought to existence with efforts Direct links to Special Articles:
    in a developed world setting in- of those who work in this new http://dx.doi.org/10.1002/biot.201000427
    clude ease-of-use, sample pro- domain of science and engineer- http://dx.doi.org/10.1002/biot.201000224
    cessing, need for skilled work- ing. We hope this issue will be of http://dx.doi.org/10.1002/biot.201000204
    http://dx.doi.org/10.1002/biot.201000100
    ers, portability, and test turn- interest to the many readers of http://dx.doi.org/10.1002/biot.201000324
    around time. These factors have BTJ across various scientific dis- http://dx.doi.org/10.1002/biot.201000340
    long limited translation of scien- ciplines. http://dx.doi.org/10.1002/biot.201000394
    http://dx.doi.org/10.1002/biot.201000105
    tific innovations to bed-side di-

    © 2011 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim 131

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