INTERNATIONAL ISLAMIC UNIVERSITY MALAYSIA

COURSE OUTLINE

Kulliyyah Science

Department Biotechnology

Programme Bachelor of Biotechnology (BBT)

Course Title Genetics

Course Code SBT 2130

Status Core Course

Level 2

Credit Hours 3

Contact Hours 5 (2 lecture hours and laboratory hours per week)

Pre-requisites Nil
(if any)

Co-requisites Nil
(if any)

Instructional The instructional strategies are:-

Strategies 1. The lecture is conducted in active participation basis (dual-way) to
prepare the students with sufficient theoretical knowledge.
2. Comprehensive laboratory experiments are given to the students to
prepare themselves with appropriate foundation technical skills to
execute research or to be applied in relevant career.
3. Industrial application related topics are given as assignments to
expose the students with real-world application of the subject.
4. Presentation of cutting-edge issues and technologies relevant to the
course are assigned to the student to update their knowledge and
enhance their communication skills.
Course LO Method %
Assessment All Quizzes 10
State weightage 2,4 Laboratory reports 20
of each type of All Mid-term examination 25
assessment. All Final Examination 45
TOTAL 100

1
Instructor(s) Assoc. Prof. Dr. Arokiaraj Pappusamy
Telephone No: 09 - 5716400 - Ext: 2826
Email: arokiaraj@iiu.edu.my

Semester Semester I
Offered
Course Synopsis This course investigates how genotypes become phenotypes: the nature of
life at the level of molecules, genes and how they function. Inheritance of
simple traits, recombination and linkage. Chromosomes, non-mendelian
inheritance, mechanisms of genetic changes and modern genetic analysis.

Course The objectives of the course are to: -

Objectives 1. Introduce genetics as the science of heredity.
2. Provide students with the basic concepts of modern genetics.
3. Help students be familiar with genetic terminologies.
4. Realize how genetics can affect individual and population as well as
help the ummah, in particular, to understand the science of genetics.

Learning At the end of the course the student will be able to:
Outcomes 1. Discuss up-to-date basic concepts of genetics.
2. Illustrate the application of technology related to genetics in
biotechnology field.
3. Demonstrate knowledge of the basic science behind the science of
genetics and understand the potential economic, social, ethical and
political impacts of the burgeoning field on society.
4. Show critical and creative thinking to solve genetics related problems
through problem solving based assessments given in the course.

Content Outlines

Weeks Topics Task/Reading

1 An Introduction to Genetics Chapter 1
Brief history and the basic concepts of genetics.
Dr. Arokiaraj
2 Cell Division and Chromosomes
Mitosis, meiosis and sexual reproduction. The significance Chapter 2
of meiosis.
(Part time lecturer)

3 Mendelian Genetics
Gregor Mendel experimental approach. The monohybrid and Chapter 3
dihybrid Cross.
(Part time lecturer)

2
4 Mendelian Genetics
Trihybrid cross. The Punnet Square and Test Cross. Chapter 3
Independent assortment and variation. Probability and
genetic event. Chi-Square analysis. Human pedigree.
(Part time lecturer)
5 Extension of Mendelian Genetics
Potential function of allele. Incomplete, partial dominance Chapter 4
and co-dominance. Multiple (ABO blood grouping) and
lethal alleles. Discontinuous variation.
(Part time lecturer)
6 Quantitative Genetics
Quantitative inheritance, analysis of polygenes traits and Chapter 5
mapping traits loci.
(Part time lecturer)
7 Linkage and Mapping in Eukaryotes
Linkage versus independent assortment. Incomplete linkage. Chapte
Single and multiple crossover. r6
(Part time lecturer)
8 Linkage and Mapping in Eukaryotes
Three point mapping. Determining gene sequences. A Chapter 6
mapping problem in maize. Multiple strand exchanges and
accuracy of mapping. Interference of the coefficient of
coincidence. Somatic cell hybridization and human gene
mapping.
(Part time lecturer)
9 Sex Chromosomes and Sex Determination
Diploid chromosomes number. Sex differentiation and sex Chapter 7
determination. The X chromosomes, Barr bodies, the Lyon
hypothesis. Aneuploidy and polyploidy: Gene deletion,
duplication, inversions and translocation.
(Part time lecturer)
10 The Molecular Basis of Genetics Chapters 9, 10
DNA structure, replication, recombination, chromosomes and 11
organization.
Dr. Arokiaraj
11 Genetic Expression Chapters 12,
The genetic code, transcription, translation. Gene mutation 13 and 14
and DNA repair.
Dr. Arokiaraj
12 Gene Regulation in Prokaryotes Chapter 16
Beta galatosidase gene of the lac operon.
Dr. Arokiaraj
13 DNA Biotechnology
Application and ethics. Mapping the human genome, the Chapters 18,
restriction length fragment polymorphisms or RLFPs. 19 and 20
Diagnosing genetics disorder, gene therapy, DNA
fingerprinting and genome projects.
Dr. Arokiaraj

3
 14 Genetics and the Ummah Discussions
Discussion on various genetics issues in Islamic society.
Dr. Ibrahim Shogar and Dr. Arokiaraj
References Required
1. Klug, W.S., & Cummings, M.R., (2002), Concepts of Genetics, 7th ed.,
Prentice Hall.

Recommended
1. Tamarin, R.H., (1999), Principles of Genetics, 6th ed., McGraw Hill.
2. Weaver, R.F., & Hedrick, P.W., (1997), Genetics, 3rd ed., McGraw Hill.
3. Mertens, T.R., & Hammersmith, R.L., (1995), Genetics Laboratory
Investigation. 10th ed., Prentice Hall.
4. Mohsin, A. F., (1993), Biomedical Issues: Islamic Perspective. 1st ed.
A.S. Norrdeen Pub.

Proposed Semester I, 2003/2004

Start Date
(Semester)
Batch of Batch 2002
Students to
be Affected

Prepared by: Checked by: Approved by:

______________ _____________________ _____________________

Assoc. Prof. Dr. Arokiaraj Kamarul Rahim Kamarudin Prof. Dr. Ridzwan Hashim
Pappusamy Head, Department of Dean, Kulliyyah of Science
Lecturer Biotechnology

NOTE:
1. The course outlines should reflect the course description/synopsis and Islamic mission of the
university as well as to provide the room for Islamic critique.
2. Latest editions of textbooks and references should be used unless otherwise necessary or if
the course is classical in nature. Please check with the library to ensure that the books are
up-to-date and incorporating the latest edition.
3. The reference lists shall be presented in accordance with APA bibliographic practices and in
alphabetical order.
4. The reference title shall be italicised or underlined or bold. If in doubt, please consult the
Librarian.
5. Proposed new course outlines should be presented to the Senate Standing Committee for
approval at least four months prior to the course offering.
6. Any changes to the course outlines must be reported back to the Standing Senate Committee
two months prior to the course offering.