NANDITA BARNABAS

1854 Huntington Boulevard, Grosse Pointe Woods, M I 48236 Home: 31Cell: 313-498-2026 nbarnab23@gmail.com

SUMMARY
Innovative Scientific Affairs Liaison with established partnerships with Physicians and Scientists. Over a decade of experience in breast, kidney, prostate cancer, Lymphoma and Leukemia diagnostics. Published in leading scientific journals. Scientific expert focused on revenue and building customer relationships. Expertise in clinical and research laboratory management, training and supervising technical staff. Experienced in teaching and mentoring graduate students. Linked in profile : www.linkedin.com/in/nanditabarnabas/

SKILL HIGHLIGHTS
Human tissue and cancer expertise Scientific adviser Assay development and validation Scientific product development Molecular diagnostics Scientific writing Hands on executive scientist Partnerships within biotechnology and medical industries Peer reviewed publications in scientific journals Clinical and research laboratory management Multilingual (English, French, Hindi, Marathi)

CORE ACCOMPLISHMENTS
Key scientific advisor for government grant funded project resulting in increased revenue for business Scientific Affairs Liaison working with physicians and scientists Scientific writing for grants, peer review publications, technical writing and standard operating protocols Published review for company which resulted in boost of cell lines sales Discovered biomarker in Leiomyosarcoma Laboratory management: supervising clinical technical staff during fellowship training Mentored graduate students in grant and thesis writing which resulted in graduation, publications and grant funding for projects Clinical interpretation of Cytogenetics during two year Fellowship in Cytogenetics

PROFESSIONAL EXPERIENCE
LINKED IN Detroit, MI Founder of group || Scientific Project Manager, Liaison, Writer Attending Networking Events Researching Industry Leaders Tracking Industry Trends Participating in Industry Discussions ASTERAND US ACQUISITION CORPORATION Detroit, MI Senior Scientific Project Administrator

10/2013 to Current

01/2013 to Current

Asterand is the leading global provider of high quality well characterized human tissue and human tissue-based research solutions to drug discovery scientists. Provided scientific expertise to leadership team, sales and operation personnel to better understand and meet customer needs. Responsible for identifying new technologies in academia and biotech based on Asterand's key goals and objectives and making initial scientific evaluation Scientific writing of articles, presentations and summaries for sales personnel, standard operating protocols . Published first author cell line review that resulted in Boost of cell line sales entitled Phenotypic and Molecular characterization of Asterand Breast Cell Lines- International Journal of Breast cancer 2013.

Spearheaded cross-functional initiative re-establishing quarantined samples in inventory resulting in increased revenue. Academic and government contracted project management. Clinical data management for The Cancer Genome Atlas Project (TCGA). Contributing author for Nature paper as a result of Asterand's collaboration with TCGA entitled Genomic Characterization of Endometrial Carcinoma. Resolve TCGA clinical data issues with the TCGA Biospecimen Core Resources . Independent genotype review for TCGA sample sets ASTERAND US ACQUISITION CORPORATION Detroit , MI 05/2011 to 12/2012 Scientific Strategy Associate Identified, negotiated, and made initial scientific evaluation for opportunities with academic and biotech collaborators and consultants. Participated and presented new technologies at Scientific Leadership Team meetings. Identify future indicators/characterization for bio-repository samples forecasting demand for human tissue. Managed projects and provided scientific recommendations and analytical services for business critical, special projects (e.g. Mutation, SNP, sequencing, and IHC testing). Worked with Chief Scientific Officer to write grant and government contract proposals. HENRY FORD HEALTH SYSTEM Detroit, MI 01/2009 to 12/2010 Postdoctoral Fellow Focus of Research : Cancer of the female genital tract . Communicated first author paper for publication entiltled "Array-CGH shows high-level of amplification of 8q including MYC as the sole aberration in a Leiomyosarcoma of the female lower genital tract Findings indicated that high-level amplification of 8q including MYC is a primary genetic abnormality as well as a pathway of evolution in Leiomyosarcoma Fellowship in Cytogenetics in accordance with the American Board of Medical Genetics regulations Clinical interpretation of Cytogenetics results Laboratory management supervising technical staff.

HENRY FORD HEALTH SYSTEM Detroit, MI 07/1999 to 12/2008 Research Scientist/Instructor Focus of Research: Prostate Cancer diagnostics Published first author paper entitled "Chromosome 8 markers of metastatic prostate cancer in African American men: Gain of the MIR151 gene and loss of the NKX3-1 gene. Presented paper at the 6th Annual Michigan Prostate Research Colloquium entitled "Androgen Receptor Gene Mutations in Prostate Cancer". Presented three first author papers at American Association Cancer Research symposiums entitled "A polymorphic variant of the Selanoprotein thioredoxin reductase type 3 is a risk factor for aggressive prostate cancer in African Americans" & "Androgen receptor GGC (glycine) repeat length polymorphism in African American men with prostate cancer" & "Is androgen receptor CAG repeat length a risk factor for aggressive prostate cancer in African American men?"

HENRY FORD HEALTH SYSTEM Detroit, MI 01/1997 to 06/1999 Associate Staff Investigator Focus of Research : Breast, Kidney and Lymphoma Biomarkers Published first author paper entitled " Mutations Compliment Prognostic and Differential Diagnostic Parameters in Renal Cell Carcinoma. Discovered that mutations in the VHL gene refined histological diagnostic criteria in renal cell carcinoma serving as adjuncts to the current morphology based diagnosis . Published first author paper entitled" Significance of p53 mutations in CLL- A sequential study of 30 patients.

Discovered mutations in exon 7 of the p53 gene occurred in patients with clinically aggressive B- cell chronic lymphocytic leukemia. Published first author paper entitled " Significance of p53 mutations in CLL- A sequential study of 30 patients. Presented author paper at the Am Assoc of Cancer Research entitled ". BRCA 1 antibodies : Evaluation of germline mutations in breast and ovarian cancers".

FOX CHASE CANCER CENTER Philadelphia, PA 01/1991 to 02/1996 Postdoctoral Research Associate Fox Chase Cancer Center is a National Cancer Institute (NCI)-designated Comprehensive Cancer Center, one of only 41 centers in the country to qualify for this highest level of designation and its researchers are frequently involved in setting new guidelines for breakthrough medicine and comprehensive care Focus of Research: Breast Cancer Biomarkers Published paper entitled " Microsatellite Instability and Loss of Heterozygosity of chromosomes 9 and 16 in Human Breast Epithelial Cells Transformed by Chemical Carcinogens. Published paper entitled " Mini Review : Molecular basis of Breast Cell Transformation. Published first author paper entitled " Role of p53 in the transformation of human breast epithelial cell line MCF 10F. Discovered p53 mutations in the spontaneously immortalized breast cell line MCF 10F compared to its mortalized counterpart. MCF 10F cell lines are susceptible to chemically induced neoplastic transformation. Published two papers entitled " Genomic scanning using endogenous LTR-like elements for rapid DNA fingerprinting of breast cancer and transformed human breast epithelial cells. & "Co- expression of C-erbB2 and Int-2 oncogenes in invasive breast carcinomas. Demonstrated alteration in genomic DNA in a clones of chemically transformed tumorigenic breast cancer cell lines using the DNA fingerprinting technology Discovered the presence of mutations in C-erbB2 and Int-2 oncogenes in Egyptian patients with histological high grade invasive breast carcinoma's

UNIVERSITY OF PARIS Paris, France 06/1989 to 12/1990 Postdoctoral fellow. Focus of Research : Breast Cancer Biomarkers Published first author paper entitled" Breast carcinoma in a high-risk population: Structural alterations in neu. int-2. and p-53 genes. Discovered structural alterations in neu, Int-2. and p-53 genes in breast cancer of Parsi women.

EDUCATION
PH.D.: BIOCHEMISTRY University of Poona, Pune, Maharashtra, India MASTER OF SCIENCE: BIOCHEMISTRY University of Poona, Pune, Maharashtra , India with honors BACHELOR OF SCIENCE: CHEMISTRY University of Poona, Pune, Maharashtra , India Minor: Physics, Zoology, Botany with honors

ADDITIONAL INFORMATION
Postdoctoral fellowship, Henry Ford Health System, USA Medical Genetics Courses, Wayne State University, USA Scholarship from Government of France. Research Merit Scholarship, Government of India

PROFESSIONAL AFFILIATIONS
American Association for Molecular Pathology (AMP) American College of Medical Genetics (ACMG) American Association for Cancer Research (AACR)

PUBLICATIONS
1.Contributing author for Nature paper in collaboration with TCGA entitled Integrated Genomic Characterization of Endometrial Carcinoma Nature 497, 67-73 (2013) URL: http://www.nature.com/nature/journal/v497/n7447 /pdf/nature12113.pdf 2.Barnabas Nandita and Cohen Dalia (2013). Phenotypic and Molecular characterization of Asterand Breast Cell Lines-.International Journal of Breast cancer (in press). 2013, Article ID 872743, 16 pages, 2013; URL: http://www.hindawi.com/journals/ijbc/2013/872743/. 3.Barnabas N, Sanchez J, Chitale D and Adeyinka A (2012). Array-CGH shows high-level of amplification of 8q including MYC as the sole aberration in a leiomyosarcoma of the female lower genital tract. (communicated to Cancer Research, under review ) 4.Nandita Barnabas, Lihua Xu, Adnan Savera, Zizheng Hou, and Evelyn R. Barrack. (2011). Chromosome 8 markers of metastatic prostate cancer in African American men: Gain of the MIR151 gene and loss of the NKX3-1 gene. The Prostate 71:857-871 5.Barnabas N.J., Amin M., Pindolia K, Nanavati R., Amin M.B and Worsham M.J. (2002). Mutations Compliment Prognostic and Differential Diagnostic Parameters in Renal Cell Carcinoma. Journal of Surgical Oncology 80:52-61. 6.Barnabas N.J., Shurafa M., VanDyke D.L., Wolman S.R., Clark D., and Worsham M .J. (2001). Significance of p53 mutations in CLL- A sequential study of 30 patients. Cancer 91(2): 285-293. 7.Wu Y.L, Barnabas N.J, Russo I.H, Yang X and Russo J (1997). Microsatellite Instability and Loss of Heterozygosity of chromosomes 9 and 16 in Human Breast Epithelial Cells Transformed by Chemical Carcinogens. Carcinogenesis 18 (5): 1069-1074. 8.Russo J, Barnabas N.J. Higgy N, Salicioni, A. M, Wu Y.L and Russo, I.H. (1996). Molecular basis of Human Breast Epithelial Cell Transformation. Advances in Biology and Therapeutics. Edt. Calvo, Crepin and Magdelenat. Pub. John Libby, Euro text, AIRMEC, France, pp 33. 9.Russo J., Barnabas NJ., Zhang P.L and Adesina K.(1996).Mini Review : Molecular basis of Breast Cell Transformation. Radiation Oncology Investigations 3: 424-429. 10.Barnabas N.J.. Moraes R., Estrada S., Calaf G and Russo J. (1995). Role of p53 in the transformation of human breast epithelial cell line MCF 10F. Int J. Oncol 7(6): 1289-1296. 11.Wahab I., Barnabas N.J, Calaf G and Russo J. (1995). Genomic scanning using endogenous LTR-like elements for rapid DNA fingerprinting of breast cancer and transformed human breast epithelial cells. Int J. Oncol 7(1): 25-31. 12.El-Gendy S., Tahin Q., El-Merzabani M., El-Aaser A.A., Barnabas N.J and Russo J. (1995) Co- expression of C-erbB2 and Int-2 oncogenes in invasive breast carcinomas. Int J Oncol: 6(5) 977-984. 13.Russo J, Calaf G, Barnabas N, Tahin Q, Zhang P.L, Alvarado M.E, Estrada S, and Russo I.H. (1993).Critical steps in Breast Carcinogenesis. Annals of the New York Academy of Sciences: 698: 1-20. 14.Barnabas-Sohi N, Simha M.R, Parikh V,Feuilhade F, Kurkure A, Kouyoumdjian J.C,Jussawalla D.J, Doctor V.M and Therwath A (1993). Breast carcinoma in a high-risk population: Structural alterations in neu. int-2. and p-53 genes. Breast Disease: 6 (1): 13-26. 15.Calaf G, Abarca J, Feuihalde F, Beaune J, Dupre G, Orrico M, Barnabas N, and Kouyoumdjian J .C. (1992) ' New cell lines of human breast cancer origin ' . Breast Canc Res and Treatment 21: 6375. 16.Barnabas N.J, Kouyoumdjian J.C, Dupre G, Feuilhade F. and Therwath A Oncogenes and Growth Factors in Breast Cancer". Journal of Cellular Biochemistry (1990) Supplement 14B. 17.Barnabas N.J., Karmalawala, R. and David S.B (1989) "Stimulation of solasodine content by growth content by growth regulators in callus cultures of the Solanum species. Ind. J.Exp. Biol. 27:664-665. 18.Barnabas N.J. and David S.B.(1988) "Solasodine production by immobilized cells and suspension cultures of Solanum surattense" Biotech Lett. 8. 593-596. 19.Barnabas N.J.and David S.B.(1987) "Immobilized techniques: A new concept in Ayurvedic Pharmacy " Deerghayu International.3(2): 4-5.

20.Barnabas N.J. (1986)."Comparative studies of stem and leaf cultures of Solanum surattense Burm. Geobios 1 (6): 233-235.

PRESENTATIONS
1.Barnabas N, Sanchez J, Chitale D and Adeyinka A. Array-CGH shows high-level of amplification of 8q including MYC as the sole aberration in a leiomyosarcoma of the female lower genital tract. American College of Medical Genetics Annual Meeting 2010. 2.Barnabas N, Xu L, Savera A and Barrack ER. Markers of prostate cancer outcome in African American men: PCM1 gene loss and miR-151 gene gain. 7th Annual Research Symposium at Henry Ford Health System Detroit MI: 2010. Won first prize. 3.Barnabas N, Xu L, Savera A and Barrack ER. Chromosome 8 gene copy number changes in aggressive prostate cancer in African American men. 8th Annual Michigan Prostate Research Colloquium and the 5th Annual Research Symposium at Henry Ford Health System Detroit MI: 2008 4.Barnabas N, Xu L, Savera A and Barrack ER. Validation of a method to Identify markers of aggressive prostate cancer. 7th Annual Michigan Prostate Research Colloquium and the 4th Annual Research Symposium at Henry Ford Health System Detroit MI: 2007 5.Javidan J, Barnabas N, De Peralta-Venturina D, Menon M , and Barrack E.R. Androgen Receptor Gene Mutations in Prostate Cancer. 6th Annual Michigan Prostate Research Colloquium and the 3rd Annual Research Symposium at Henry Ford Health System Detroit MI: 2006 6.Barnabas N, McIntire L.L, Christopherson P.L, Amin M, Menon M and Barrack E.R. A polymorphic variant of the selanoprotein thioredoxin reductase type 3 is a risk factor for aggressive prostate cancer in African Americans. Proc. Am. Assoc Canc Res, 45: 2004; Proc. 4th Annual Symposium of the Michigan Prostate Research Colloquium April 2004; 1st Annual Research Symposium at Henry Ford Health System Detroit MI: 2004. 7.Barnabas N, McIntire L.L, Amin M, Christopherson P.L, Menon M and Barrack E.R. Androgen receptor GGC (glycine) repeat length polymorphism in African American men with prostate cancer. Proc. Am. Assoc Canc Res, 44:214, 2003. 8.Barnabas N,McCintire L.L, Amin A,Divine G, Xu L, Christopherson P.L,Menon M, Abrahms J and Evelyn Barrack. Is androgen receptor CAG repeat length a risk factor for aggressive prostate cancer in African American men? Proc. Am. Assoc Canc Res, 43: 2002. 9. Barnabas N ,Christopherson P.L,McIntire L.L,Menon M and Barrack E.R. GSTP1 polymorphism, a potential risk factor for prostate cancer: Genotyping paraffin embedded DNA. 1st Annual Symposium of Michigan Prostate Research Colloquium 2001 10.Amin M, Barnabas N, Pindolia K, Nanavati R, Tamboli P, Amin MB and Worsham M. Mutational Analysis of the Von-Hippel Landau (VHL) gene in Adult Renal Epithelial Neoplasm's (REN) with abundant granular cytoplasm. 89th annual meeting of the USCAP. New Orleans. March 2000 11.Barnabas N.J., Amin M., Pindolia K, Nanavati R., Amin M.B and Worsham M.B. Mutations in the VHL gene as biomarkers of histological discrimination in renal epithelial neoplasia. Proc. Am. Soc. Hum Genet. Presented January 2000. 12.Shurafa M., Barnabas N.J., VanDyke D.L., Wolman S.R., Clark D., and Worsham M J. Significance of p53 mutations in CLL- A sequential study of 30 patients. VIII International workshop on CLL held in Paris, France. 1999. 13.Barnabas N.J., Amin M., Nanavati R., Pindolia K, Amin M.B and Worsham M.B. Utility of the VHL gene in sub typing renal epithelial neoplasia (REN) .Proc. Am. Assoc Canc Res, 40: (Abstract #1829) 1999. 14.Amin M., Barnabas N.J., Nanavati R., Amin M.B and Worsham M.J. Granular renal Cell carcinoma (RCC) not otherwise specified (NOS) a distinctive subtype of RCC? : An investigation using mutational analysis of von HippelLandau (VHL) gene. 88th annual meeting of the USCAP at San Francisco, Abstract in Mod Pathol 12:87A, 1999. *Von Stowell-Orbinso award of honorable mention. 15.Barnabas N.J., Shurafa M., Van Dyke D.L., Clark D and Worsham M.J. p53: A Prognostic marker of rapid progression in CLL. Proc Am. Assoc Canc Res 39: 1998. 16.Worsham M.J., Barnabas N.J., Raju U., Pals G., Herrington, C.S., Zarbo, R.J., Nathanson, S.D and Wolman, S.R. BRCA 1 antibodies : Evaluation of germline mutations in breast and ovarian cancers. Proc Am. Assoc Canc Res 39: 1998. 17.Worsham M.J, Barnabas N.J. ., Raju U., Pals G., Wolman S., Herrington S and Zarbo R.J Evaluation of BRCA1 antibodies as a screening tool for germline BRCA 1 mutations. Presented at the Association for Molecular Pathology conference in November 1997. 18.Worsham M.J, Barnabas N.J. ., Raju U., Pals G and Wolman S. Evaluation of the ATM locus as a contributing factor in development/progression of BRCA1 germline mutations. Association of Molecular Pathology (AMP) meeting 1997. 19.Barnabas N.J. Wu Y L, Russo I.H, Yang X and Russo J . Microsatellite Instability and Loss of Heterozygosity of

chromosomes 9 and 16 in Human Breast Epithelial Cells Transformed by Chemical Carcinogens. Proc AACR annual meeting 1996. 20.Russo. J., Russo l.H., Calaf G., Zhang P.L and Barnabas N.J. (1995) Breast susceptibility to carcinogenesis. In: Hormonal Carcinogenesis. Proceedings of the second International Symposium. Edit Jonathan Li. 21.Barnabas N.J.,Moraes R., Estrada S., Calaf G and Russo J. Role of p53 in the transformation of human breast epithelial cell line MCF 10F. *Platform presentation at the 1995 AACR meeting.. 22.Barnabas N.J., Wahab I., Calaf G and Russo J. Genomic scanning using endogenous LTR-like elements for rapid DNA fingerprinting of breast cancer and transformed human breast epithelial cells. *Platform presentation at the 1995 AACR meeting. 23.El-Gendy S., Tahin Q., El-Merzabani M., El-Aaser A.A., Barnabas N.J and Russo J. (1995) Co- expression of C-erbB2 and Int-2 oncogenes in invasive breast carcinomas. Proc AACR annual meeting 1995