Name of Drug

Classification

Action

Indication

Side Effects

Intervention and Evaluation

1. Check for doctors order 2. Monitor blood pressure and pulse rate before and after giving the meds. 3. Notify prescribing signs of heart failure such as swelling of hands and feet or SOB. 4. Advise patient of the side effects of the drug.

Trimetazidine (Generic name) Vastarel (brand name)

Anti - Angina

Selective inhibition of an enzyme of fatty acid oxidation: the long- chain 3-ketoacyl CoA thiolase (3- KAT). This inhibition results in: Reduction in fatty acid oxidation; Stimulation of glucose oxidation. The coupling of glycolysis with glucose oxidation is improved and ATP production is further increased, while cell acidosis and Ca2+ overload are limited. The increase in total glucose utilization has been evidenced by studies using 18FDG positron emission tomography (PET).

- acute anginal attacks - prevent situation that may cause anginal attacks

Nausea and Vomiting, headache, edema

Name of Drug

Classification

Action

Indication

Side Effects

Intervention and Evaluation

Report for adverse effects Offer small frequent feeding Encour age bed rest

Celecoxib
(Generic name) Celebrex (brand Name) Dosage: 400 mg OD p.r.n

Antirheumatic, NSAIDS

the enzyme COX-2. This enzyme is required for the synthesis of prostaglandins. Have analgesic, antiinflammatory and antipyretic properties.

Relief of signs and symptoms of osteoarthritis, rheumatoid arthritis, ankylosing spondilitis, and juvenile rheumatoid arthritis, and management of acute pain CONTRAINDICATION: hypersensitivity; with history of asthma, urticaria, advance renal disease

dizziness, headache, insomnia,edema, abdominal pain, diarrhea, abdominal pain, flatulence, nausea Adverse Effects: bleeding, toxic epidermal necrolysis, stevensJohnson syndrome

Name of Drug

Classification

Action

Indication

Side Effects

Intervention and Evaluation

Rebamipide
(Generic name)

Mucosta
(Brand Name) Order Dose: (PO) 1 tablet 3 x a day

Antacids, Antireflux Agents & Antiulcerants

Rebamipide is a mucosal protective agent and is postulated to increase gastric blood flow, prostaglandin biosynthesis and decrease free oxygen radicals

Acute gastritis and Acute exacerbation of chronic gastritis Gastric ulcer

GI: constipation, bloating, diarrhea, nausea, vomiting SKIN: rash, pruritus

Contraindication: Hypersensitivity to this drug

Can be taken with meals or without meals Assess if hypersensitive to drug Assess for GI symptoms Assess for skin rashes and other allergic reactions Teach to take medications religiously to promote faster healing