Mimics Innovation Suite

Take your CT / MRI images to the next level

Have a passion for biomedical R&D? So do we.

At Materialise, we are committed to our role in creating a better and healthier world. We are proud that the Mimics Innovation Suite is providing the necessary tools to advance biomedical R&D. With the Mimics Innovation Suite and Materialise as your partner, the possibilities are endless. The Mimics Innovation Suite is the tool of choice by top universities and medical device manufacturers for a wide variety of R&D challenges. Satisfy all your research needs with one state-of-the art solution Perform detailed accuracy studies for validation purposes Achieve shorter time-to-patient for implants and prosthetics through virtual design iterations Improve implant longevity by optimizing stress distribution Enhance the efciency of medical devices by ow optimization Virtually analyze 3D patient geometry to decide upon the best treatment or to discard non-effective treatments Optimize generic implants via statistical population analyses Decrease surgery time through the use of patient-specic implants and surgical guides

Our total solution

The Mimics Innovation Suite is a complete solution comprised of three strong tools that can be used as stand-alone products, but are more powerful when used together. Mimics medical image processing software 3-matic design, meshing and geometry optimization software Services engineering, consultancy and custom software development

Mimics and 3-matic interface seamlessly offering you the ability to process and edit anatomical data as well as design, mesh and optimize geometries. The various modules allow you to customize a solution for your needs. Combining 3D patient data with CAD data and exporting complex anatomical data to your CAD, CAM or FEA package has never been more accurate, exible and efcient. With two new releases per year, the Mimics Innovation Suite is under constant development to stay on the cutting edge of technological advancements. In addition, our ISO quality system and FDA and CE market clearances make Materialise an ideal partner for biomedical research and development.

Mimics Innovation Suite

Scanner data (CT, MRI, CT) Image data (tiff, jpeg, bmp) STL data CAD data Point cloud data

Mesh Design Combine Segment Analyze Modify Optimize Create

FEA/CFD CAD CAM Surgical planning Statistical analysis Additive manufacturing

Engineering services, consultancy and custom software development

Software is what we develop, solutions are what we provide.

Koen Engelborghs, Director Biomedical Engineering, Materialise

Engineering on anatomy

Mimics
Bridge the gap between 2D image data & 3D engineering applications
Mimics software allows you to process and edit your 2D image data (CT, CT, MRI, etc.) to construct 3D models with the utmost accuracy, exibility and user friendliness. The powerful segmentation tools allow you to segment your medical CT/MRI images, take measurements and engineer directly on your 3D model. From there you can export your 3D data to a wide range of output formats and engineering applications; such as FEA, design, surgical simulation, additive manufacturing and more. 1

3-matic
Fast-forward design & geometry meshing
3D data from Mimics can be used in 3-matic to perform a variety of design and meshing operations directly on the anatomical data thereby eliminating the need for the lengthy, error-prone process of reverse engineering. This will maximize accuracy and save time. Your anatomical data or design can then be exported to any CAD and all major CAE packages, making 3-matic the perfect complement to your normal workow.

Engineering services & consultancy

Increase efciency with minimal effort
Materialises team of skilled professionals are available to collaborate with you on your biomedical R&D challenges. Theres no more efcient way of getting the desired results. We can complete portions of projects or the entire effort: its up to you. Consulting services to improve products or streamline your process are also available. We can even develop customized software solutions. Whatever the bottleneck or need, we can help.

1 Data courtesy of Dr. Stephen Rouse, Walter Reed Army Medical Center, USA

Engineering on anatomy
3

From 2D to 3D: visualize the invisible

With the Mimics Innovation Suite, you can construct a virtual 3D model from imported 2D image data and navigate the axial (XY), coronal (XZ) and sagittal (YZ) views. From there, data manipulation can be performed in one of the 2D views or directly on the 3D model. Combine the Mimics Innovation Suite with non-invasive medical imaging to: Perform fast segmentations Generate accurate 3D models of regions of interest Examine, manipulate, measure and engineer directly on the anatomical data

Measurements: examine your 3D model in detail

The software allows you to accurately measure distances, angles, diameters or densities either on your 2D images or directly on the 3D model. Rely on the Mimics Innovation Suite to: Perform advanced geometrical analyses: wall thickness, part comparison or curvature Calculate more dedicated measurements: vessel centerlines and diameters/tortuosity of arteries, veins or airways Investigate the porosity or connectivity of bone, tissue engineering scaffolds or any other porous material using micro-CT data Take repetitive measurements using your own anthropometric templates Export measurements for statistical analysis Compare pre- and post-operative data Create construction geometries that facilitate the most complex measurements and analyses

15,29mm^2

0,22

2,77mm

7,72mm

Surgical simulations: planned and proved

With the Mimics Innovation Suite, operation time may be reduced by your ability to simulate surgical interventions on patient data. This allows you to derive optimal surgical plans by evaluating outcomes of various approaches, validate custom implants and make changes to the surgical plan. Mimics literally transforms your computer into a virtual operating room where you can experiment with a variety of solutions. Now, you can easily and virtually: Plan cutting planes for osteotomies Reposition bone parts, place plates and screws, t and position implants, place distractors, calculate volumes, etc. Take bone grafts, assess available bone for the graft, determine its size and implant the bone where needed

Patient-specic designs: implants & guides

It is no longer difcult to perform design operations on complex anatomical data. Our forward engineering technology provides you with the full range of standard CAD tools to design your patient-specic implants and surgical guides directly on the anatomical data ensuring a perfect t and eliminating the lengthy and errorprone process of reverse engineering. In addition, virtual design iterations shorten the time-to-patient. The Mimics Innovation Suite also allows you to develop patient-specic surgical guides for minimally invasive surgery. These ensure that virtual surgery plans are accurately transferred to the patient, reducing intra-operative decision-making. Following the patient-specic approach, you will be able to shorten the intervention period, reduce OR costs, decrease anaesthesia time and expedite the patients recovery. 1 Our software allows you to: Use standard CAD tools, such as extrude, offset, hollow, mirror and boolean operations Ensure perfect t and placement of your implant by effortlessly removing undercuts Smooth your data and design with shrinkwrap Dene macros for frequently used work ows Export to the FEA/CFD package of your choice

FEA or CFD: from scan data to analyses

Finite element simulations are extremely useful to assess, ex-vivo, local stresses, strains or pressures as a result of affecting forces or ows on anatomical structures or implants. They help understand biomechanical phenomena and improve implant performance. With the Mimics Innovation Suite, preparing complex anatomical geometries for accurate simulations is no longer a time-consuming, complicated task. By working directly on mesh les during the entire process, preparation time is signicantly reduced. As the Mimics Innovation Suite combines design and meshing operations, you can modify your designs based on the simulation outcomes. Our solutions make FEA: Fast, Easy and Accurate. 2 Use the Mimics Innovation Suite on image-based 3D data to: Optimize and defeature surface meshes Generate volume meshes semi-automatically Assign material properties based on image gray values for more accurate simulations Export to FEA/CFD package of your choice

The Mimics Innovation Suite has enabled sophisticated, multi-component nite element models of complex anatomical structures to be generated from CT and MR data. The advent of forward engineering (digital CAD) signicantly reduces design time and simplies the modeling process.
Simon N. Collins, Ph.D. - Centre for Equine Studies, Animal Health Trust, UK

1 Data courtesy of IDEE and Dr. Poukens, Unversity Hospital of Maastricht 2 Image courtesy of P .J. Antunes, University of Minho, Portugal

Engineering on anatomy
5

No matter how good 3D images are; there is nothing like a model in your hands
H.K. Kawamoto, MD DDS, UCLA Medical Center, USA

Additive manufacturing: from virtual to tangible

The virtual 3D models produced in the Mimics Innovation Suite allow you to print a 3D reconstruction of any scanner image using additive manufacturing* (AM) technology. Physical models allow you to explore and evaluate patient anatomy to gain better insight into specic pathology. This knowledge facilitates medical g diagnoses. 3D models are also an excellent tool for discussing treatments with diag dia patients or the medical team. They even allow you to bend plates and t implants pa ati to the th model prior to surgery. Materialise can manufacture parts for you in a wide variety var rie of materials. The Mimics Innovation Suite allows you to: The Ensure manufacturability by dening wall thickness Design auxiliary components or internal structures using the common CAD tools Perform very complex cuts Export the most complex geometries to any AM machine Save material by shrinkwrapping and hollowing your parts
*A Additive d manufacturing (AM) is also known as rapid prototyping (RP)

CAD: convert freeform geometry data

Importing anatomical data into CAD or generating NURBS surface data for CNC milling requires that data is converted. Converting data our way allows you to: Smooth and split your freeform geometry automatically into denable patches Export as a solid to IGES or STEP format while keeping the le size small Avoid reverse engineering and needing to simplify/smooth complex shapes Perform CAD operations directly on anatomical data

Other possibilities: theres no limit

Nearly all applications that begin with scanned data benet from the tools and capabilities of the Mimics Innovation Suite. A few applications beyond the medical realm include: Understanding animal anatomy Researching mummy pathology Studying 3D models of technical parts derived from CT scans such as historic musical instruments or engine blocks Modeling the surface of the planet Mars

Added value: above and beyond just software

Maintenance
Get the most out of your software
At Materialise, theres more to a maintenance agreement than receiving the latest software upgrades for free. As a maintenance customer, you can participate in update training to learn the latest features of our software, receive discounts on Materialise events, enjoy full access to the Mimics User Community and of course, our application engineers are always available to answer your questions.

Training
Expand your skills
To improve your efciency, we provide comprehensive training on a regular basis at our ofces around the world. We can also provide customized training at your facility. Our Innovation Courses are another great way to gain a better understanding of the Mimics Innovation Suite and what it can do for you.

I would strongly recommend Innovation Courses to all serious users. The presentations were very professional and the enthusiasm of the Materialise staff made it fun.
Bruno Frohlich - Smithsonian Institute, USA

Mimics User Community

Uniting experts
For additional support, the Mimics User Community is an online portal offering FAQs, tips and tricks, tutorials, scientic articles, discussion forums, news, event announcements and much more. You can even publish your resume/CV or post job opportunities which require Mimics skills.

Mimics Innovation Awards

Rewarding & acknowledging users
It is exciting to see how the Mimics Innovation Suite is making cutting-edge research possible. Materialise recognizes the value of this R&D through the Mimics Innovation Awards. High-level researchers from all over the world submit papers to win monetary prizes in support of their efforts.

Engineering on anatomy
7

Why choose the Mimics Innovation Suite?

Made by Materialise
Materialise began in 1990 as a specialist in rapid prototyping (RP) and additive manufacturing (AM) and has grown into the market leader for 3D printing and digital CAD software. Materialise has the largest capacity AM facility under one roof and is a major player in medical and dental image processing and surgery simulation software. Its medical and dental products are used worldwide by renowned hospitals, research institutes, medical device companies and clinicians. This makes Materialise the perfect partner for those involved in cutting-edge, innovative biomedical R&D. The company has acted as a pioneer in many elds and has been investing for years in advancing research. Materialise has the largest development team in the sector and several subsidiaries in Europe, Asia and the United States.

Developed in an ISO 13485 Environment

Mimics, 3-matic, Materialise and other names mentioned in this document are registered trademarks and/or trade names owned by Materialise. These and all other trademarks and trade names used in this document are protected by trademark laws. No user has any right, title, or interest in those marks or names not previously expressly granted in writing to such user by Materialise.

For more information: medical@materialise.com or www.materialise.com/BiomedicalResearch

www.materialise.com