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Q1. What is an antitussive? Ans: A medicinal drug used in an attempt to treat coughing and related conditions.

For dry coughs, treatment with cough suppressants (antitussives) may be attempted to suppress the body's urge to cough. Q2. What is dextromethorphan? Ans: Dextromethorphan (DXM or DM) is an antitussive (cough suppressant) drug used to treat dry cough Dextromethorphan is an opiate derivative with good antitussive activity, but it does not have activity at opiate receptors and is not analgesic or addictive. Q3. What is the dose of Dextromethorphan in various age groups of children? Age Range 1 to 3 months 4 to 6 months: 7 months to 1 year 2 to 6 years 7 to 12 years 12 years or older Dose 0.5 to 1 mg orally every 6 to 8 hours. 1 to 2 mg orally every 6 to 8 hours 2 to 4 mg orally every 6 to 8 hours 2.5 to 7.5 mg orally every 4 to 8 hours. 5 to 10 mg orally every 4 hours or 15 mg every 6 to 8 hours. 10 to 30 mg orally every 4 to 8 hours. Maximum Dose per day

Maximum dose: 30 mg/day. Maximum dose: 60 mg/day. Maximum dose: 120 mg/day.

Note: Dosage in children less than 4 years of age is not well established Ref: Drugs.com

Q4. What are the different anit tussives available for dry cough? Ans: Codeine, Pholcodiene, Levodropropizine, levocloperastine

Q5. What are anti histaminics? Ans: Anti histamincs are drugs that block the H1 receptors and are used to treat allergic reactions caused due to allergens. Q6. Which anti histamics are generally used with anti tussives? Ans: Chlorpheniramine, Promethazine, Triprolidine

Q7. How much calorie does 1 gram of sugar contain? And : 4 calories Q8. What are Sugar Substitutes? Ans: Polyols are carbohydrates but they are not sugars, making them sugar-free sweeteners. Eg. Maltitol, Erythritol, Sorbitol, Xylitol, Lactitol Q9. Difference between various polyols?
Properties Calories/gm Sweetness compared to Sugar Tooth Decay/Dental Caries Other Properties GRAS Status Maltittol 2.1 90% Erythritol 0 70% Sortbitol 2.6 60% Xylitol 2.4 NA Lactitol 2 40%

No

No

No

No

No

yes

yes

yes

yes

Prebiotic majorly used as a laxative NA

Q10. How does sugar cause tooth decay?

Ans: After eating sugar it adheres to the teeth to start the formation of plaque. At the same time millions of bacteria known as Streptococcus mutans also adhere to the teeth. Although, many oral bacteria also adhere, only the S. mutans is able to cause cavities. In the next stage, the bacteria use the fructose ( from the sugar eaten) to get energy. Due to bacteria, fructose gets converted to lactic acid. The lactic acid creates extra acidity to decrease the pH to the extent of dissolving the calcium phosphate in the tooth enamel leading to the start of a cavity or tooth decay.
Bacteria use fructose for energy

Lactic Acid causes tooth decay

Q11. How Does Maltitol not cause tooth decay? Ans: Maltitol is resistant to attack by oral bacteria, thus does not form lactic acid and thus does not cause Tooth decay/Dental caries Q12. What is GRAS? Ans: GRAS is (Generally Recognised as Safe) and this status is given by US FDA to foods/ molecules that are regarded as safe for consumption in humans of all ages

Q13. Who are the competitors of Alex Junior?


Brand Name Chericof Ascoril D Piriton CS Protussa Actifed DM Tixylix Ambrolite D Company Ranbaxy Glenmark GSK Abbott GSK Abbott Tablets India Composition/ 5 ml Dextromethorphan 10 mg + Chlorpheniramine 4 mg Dextromethorphan 10 mg+ Triprolidine 1.25 mg + Phenylephrine 5mg Dextromethorphan 10 mg + Chlorpheniramine 4 mg Dextromethorphan 5 mg + Chlorpheniramine 1 mg Dextromethorphan 10 mg+ Triprolidine 1.25 mg Pholcodeine 1.5 mg + Promethazine 1.5 mg Dextromethorphan 10 mg+ Triprolidine 1.25 mg Pack Size 60 ml 100 ml 100 ml 60 ml 100 ml 60 ml 60 ml MRP 32.50 65.00 54.50 53.00 49.50 48.87 31.70

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