o Convlnclng: 8ed meaL and processed meaL o Convlnclng: Lxcess body faL, sLomach o Convlnclng: Lxcess alcohol lnLake ln males o robable: Lxcess alcohol lnLake ln females o Convlnclng: hyslcal acuvlLy reduces rlsk Ametlcoo losutote fot coocet keseotcb, 8y coocet 5lte, ovolloble ot. bup.//www.olct.otq/teJoce-yoot-coocet-tlsk/coocet-slte/ Col orectal Cancer Preventabil ity o AlC8 esumaLes LhaL posluve changes ln: 8ed meaL, processed meaL, excess alcohol, faLness, lnacuvlLy o Could prevenL 43 of colorecLal cancer ln uS every year o 64,000 cases per year Ametlcoo losutote fot coocet keseotcb, 8y coocet 5lte, ovolloble ot. bup.//www.olct.otq/teJoce-yoot-coocet-tlsk/coocet-slte/ Meat Consumption o 1999: 218 mllllon Lons annual, global o 2030: 376 mllllon Lons annually predlcLed o Consumpuon of red and processed meaL has been assoclaLed wlLh lncreased rlsk colorecLal cancer o !"#$%&'"# )*+,--*./01,.2 34-45 )*/ -*05 5, 6 78 ,9 :;<< => ?*) @**AB -4.4-49* ?),+*CC*/ wotlJ coocet keseotcb looJ ooJ Ametlcoo losutote fot coocet keseotcb, 5ecooJ xpett kepott. looJ, Nottluoo, lbyslcol Acuvlty & 1be lteveouoo of coocet, 2007. Proposed Mechanisms: Meat & Ca o Peme lron ln red meaL may serve as caLalysL ln guL Lo generaLe free radlcals, damaglng unA o Carclnogens formed durlng hlgh heaL cooklng, processed meaLs oen cooked aL hlgh heaL o rocessed meaLs may conLaln nlLrlLes LhaL become carclnogenlc nlLrosamlnes Meat Consumption Trends wotlJ coocet keseotcb looJ ooJ lAO 1rends ln meaL consumpuon over ume (kg/per caplLa/per year) Meat Consumption Trends wotlJ coocet keseotcb looJ ooJ lAO 1rends ln meaL consumpuon over ume (kg/per caplLa/per year) by reglon Research: Fiber and Col on Cancer o 2011, 8M!, meLa-analysls of 23 sLudles o 1oLal ber lnLake - lncludlng from whole gralns and cereals - sLrongly llnked Lo reducuon ln colon cancer rlsk o Lvldence weaker for ber from frulLs, vegeLables, legumes o 7<D )4CA )*/E+1,. 4. +,3,)*+503 +0.+*) F,) *0+G 7< =)0-C ,F HI*) *05*. ?*) /0J o Assoclauon, noL cause and eecL 8MI. 2011 Nov 10,J4J.J6617 Research: Cal cium & Col orectal Ca o 2009, nCl, 36,963 male cancer cases, 16,603 female o Calclum lnLake noL relaLed Lo LoLal ca ln men o Was nonllnearly assoclaLed wlLh LoLal ca ln women - rlsk decreased up Lo approxlmaLely 1300 mg/day (above LhaL, no furLher 88) o Males & females: dalry food & calclum lnversely assoclaLed wlLh cancer of dlgesuve sysLem o K*+)*0C*/ )4CA ?0)1+E30)3J ?),.,E.+*/ 4. +,3,)*+503 +0.+*) o SupplemenLal calclum lnLake also lnversely assoclaLed wlLh colorecLal cancer rlsk Atcb loteto MeJ. 2009 leb 2J,169(4).J91-401 Research: Exercise & Col on Ca o nlP-AA8 uleL and PealLh SLudy, n=488,720 aged 30-71 o L*. @G, *.=0=*/ 4. C?,)5C ,) *M*)+4C* 05 3*0C5 ; 1-*C ?*) @**A G0/ N<D 3,@*) )4CA +,3,. +0.+*) 5G0. -*. @G, )0)*3J%.*O*) *M*)+4C*/ o 20 hlgher rlsk for men who waLched 1v or vldeos for 3 or 6 hours a day Lhan men who waLched less Lhan 3 hours o lmpacL of exerclse less clear for women coocet cooses coottol. 2008 Nov,19(9).9J9-5J. For More Infor mation o Parvard SP llbet ooJ coloo coocet. lollowloq tbe 5cleoufc 1toll hup://www.hsph.harvard.edu/ nuLrluonsource/nuLrluon-news/ber-and- colon-cancer/lndex.hLml