Addiction Workshop MSCL Answer the following questions regarding buprenorphine and methadone and their roles in the

management of opioid addiction. Answers should be in the form of structured, written answers that are at least 500 words in length each. Questions 1. What type of medicines are methadone and buprenorphine? Explain how they help in the management of opioid addiction 2. Is it possible to say whether methadone or buprenorphine is a better treatment option? Provide rationale arguments for your decision and consider the effectiveness, side effects and risks associated with each 3. Do patients have a preference for either methadone or buprenorphine? Is this preference consistent with different patient groups Suggested Resources (You do not have to access all of these, but they will help you) (All available from http://www.kent.ac.uk/library/online/journals/index.html unless otherwise noted) Connock M, Juarez-Garcia A, Jowett S et al (2007). Methadone and buprenorphine for the management of opioid dependence: a systematic review and economic evaluation. Health Technology Assessment (Winchester, England); 11(9): 1-171. Department of Health (2007) Drug Misuse and Dependence: UK Guidelines on Clinical Management Available from http://www.nta.nhs.uk/uploads/clinical_guidelines_2007.pdf (accessed 8th November 2010) Pinot H, Maskey V, Swift L et al (2010). The SUMMIT trial: a field comparison of buprenorphine versus methadone maintenance treatment. Journal of Substance Abuse Treatment; 39(4): 340-52. Ponizovsky A.M and Grinshpoon A (2007). Quality of life among heroin users on buprenorphine versus methadone maintenance. American Journal of Drug and Alcohol Abuse; 33(5): 631-42. Ridge G, Gossoop M, Lintzeris N et al (2009). Factors associated with the prescribing of buprenorphine or methadone for the treatment of opiate dependence. Journal of Substance Abuse Treatment; 37(1): 95-100. Schwartz R.P, Kelley S.M, OGrady K.E et al (2008). Attitudes toward buprenorphine and methadone among opioid-dependent individuals. American Journal on Addictions; 17(5): 396-401.