Pathophysiology of Rheumatic Heart Disease/Rheumatic Heart Fever

Predisposing Factors -Genetic father have RHD -Rheumatic heart disease since childhood -Most common in Male than female -Age most common from 5-15 yrs of age

Precipitating Factors -Smoking -Lifestyle(inking and tattooing) -Sore Throat last June -Uncompliance to medications

Gentamicin and Ceftriaxone

Streptococcal infection

Increased WBC

Increase production of antigen(strept ococci) Bind to receptors in the synovial joints Antigen circulates to the system Autoimmune Response attack the heart valves

Autoimmune response Antigen are similar to bodys own cell that may result to attack of healthy body cells by mistake

Increased ESR

Inflammation of the layers of the heart

Difficulty of heart to pump

Collection of collagen fibers over the bones and tendons

Inflammation

Increase cardiac work load

(+) Joint pains Subcutaneous Nodules

Scarring of the heart valves that damages (Mitral or Aortic valve)

Aspirin

Decrease cardiac supply of blood in different organs Neobloc Lanoxin

Decrease blood in the bone marrow

Decrease RBC production

Blood cell production slows down

Decrease in hemoglobin and iron rich protein

Decrease WBC production

Shortness of breath and Tachycardia

Decrease immune defense reaction

Increase risk for infection Decreased RBC and Hematocrit Decrease oxygen in the body

Systemic infection still occurs

Fever

Generalized body weakness

Increased Platelet

Rashes (Erythema Nodosum and Maculopapular Rash

Paracetamol Centrum Acknil

Legend LABS

SIGNS AND SYMPTOMS

MEDICATIONS

Rheumatic Heart Disease/Rheumatic Heart Fever Pathophysiology connected to Dyspnea

Blood cell production slows down

Blood cell production slows down

Decrease in hemoglobin and iron rich protein

Lung and Lower Airway Mechanoreceptors - Stretch receptors - Irritant receptors - J receptors

Upper airway mechanoreceptors and flow receptors

Chest wall mechanoreceptors

Brainstem Respiratory Complex Sensory Cortex

DYSPNEA