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severe anemia: extremely low rbc... low wbc, but high platelet count..
Female, age 79
Already had one blood transfusion on July 24, and this is the blood test result for today... Doctor had ordered bone marrow aspiration, but we won't be able to get it
done until mid September.... Does this look like some sort of leukemia? Please help ....
(*** : abnormal result)
*** rbc 1.85 (normal range reference: 3.5-5.5)
*** wbc 3.75 (4.0-10.0)
*** hgb 62 g/L(110-150)
*** hct 18.4 %(34-45)
*** mcv 99.2 fL(82-99)
*** mch 33.5 pg(27-33)
mchc 337 g/L (320-360)
*** rbc-dw 18.8 %(11-16)
*** platelet count 361(100-360)
pdw 16.3 % (10-20)
mpv 12 fL (6.0-12.5)
pct 0.43 %(0.11-0.43)
*** NEUT# XXXXX(2.0-7.0)
LYM# XXXXX (0.8-4.0)
MONO# XXXXX (0.1-1.0)
EOS# XXXXX (0.0-0.5)
BAS# XXXXX (0.0-0.1)
*** NEUT% 36.7 (50-70)
*** LYMPH% 45.2 (20-40)
*** MONO 10.9 (2.0-10.0)
*** EOS% 5.60 (0.0-5.0)
*** BAS% 1.60 (0.0-1.0)
Submitted: 1 year ago.
Category: Health
Expert: Dr. Brims replied 1 year ago.
Dr Brims :
Hello, welcome to Justanswer, I will try to assist you with your medical question, and any medical information you seek
Dr Brims :
This does not seem like leukemia at all, it seems like there is some bone marrow failure, although the platelet count is high, so that is a bit odd.I suspect that is the
reason why they want to do a bone marrow biopsy
Dr Brims :
I'm sorry to hear about this, but try to be patient, the bone marrow biopsy will shed mo
re light, and this is not leukemia
Customer:
Thank you so much for your reply!
It is such a big relief for us to hear that this is not leukemia...
Before the blood transfusion, her platelet count was even higher than this, and she also had a high iron blood level (35.0 umol/L compare to normal upper limit 30.4),
and she has uncontrolled type II diabetes for many years (around 10 mmol/L compare to normal range<3.6-6.1>), but she's quite healthy other than the diabetic
problem...
I understand without seeing the bone marrow biopsy result, it is very hard to guess what is really causing her problem, but based on the the blood test result, could
you give us a little bit hint on what type of bone marrow failure this could be? Could it be aplastic anemia, sideroblastic anemia or myelodysplastic syndromes, or
something else....?
the following is her blood test result before the blood transfusion on July 24th, just in case it might provide some more useful information for you.
*** rbc 1.42 (normal range reference: 3.5-5.5) *** wbc 3.91 (4.0-10.0) *** hgb 51 g/L(110-150) *** hct 15.4 %(34-45) *** mcv 108.7 fL(82-99) *** mch 35.9
pg(27-33) mchc 331 g/L (320-360) *** rbc-dw 16.7 %(11-16) *** platelet count 380(100-360) pdw 16.0 % (10-20) mpv 12.2 fL (6.0-12.5) pct 0.46 %(0.11-0.43)
*** NEUT# XXXXX(2.0-7.0) LYM# XXXXX (0.8-4.0) MONO# XXXXX (0.1-1.0) EOS# XXXXX (0.0-0.5) BAS# XXXXX (0.0-0.1) *** NEUT% 43.8 (50-70) *** LYMPH%
45.3 (20-40) *** MONO 8.2 (2.0-10.0) *** EOS% 1.30 (0.0-5.0) *** BAS% 1.40 (0.0-1.0)
Customer:
BTW, the above test was done right before the blood transfusion...
Dr Brims :
Sorry, please let me read your reply
Customer:
Hi Doctor, are you there?
Dr Brims :
I am here now
Customer:
Thanks for your reply doctor!
Customer:
I was just wondering if you have got a chance to take a look at her blood test result right before the blood transfusion..
Customer:
She had a high iron blood level and even higher blood platelet count....
Dr Brims :
I saw it, sorry for the delay
Customer:
no problem :)
Dr Brims :
The truth is , these results don't fit into any disease profile exactly, that is why there is no way to classify it, but it may be a type of myelody
splastic syndrome
Customer:
i see......
Customer:
Is there anything we could do to help her feel better before we can get the bone marrow biopsy done? The test was scheduled in 3 weeks from now...
Dr Brims :
Is she taking any iron supplements?
Customer:
no... I don't think so, she's been taking folic acid and B12
Dr Brims :
Okay, then she may want to consider also taking iron supplements as well
Customer:
Her iron blood level is already higher than the normal range now... is it ok to take more iron supplement?
Dr Brims :
What are her serum iron levels?
Customer:
her iron blood level was at 35.0 umol/L (compare to normal upper limit reference 30.4), that was right before the blood transfusion...
Dr Brims :
Okay, then she should not take iron supplements
Lower limit
Upper limit
Unit
135,[8] 137[9][4]
145,[9][4] 147[8]
mmol/L or mEq/L[8]
Comments
310,[10] 320[10]
330,[10] 340[10]
mg/dl
3.5,[8][4] 3.6[9]
5.0,[8][9][4] 5.1
mmol/L or mEq/L[8]
14[11]
20[11]
mg/dl
mmol/L or mEq/L[8]
340[13]
370[13]
mg/dl
1.03,[14] 1.10[4]
1.23,[14] 1.30[4]
mmol/L
4.1,[15] 4.4[15]
4.9,[15] 5.2[15]
[8][16]
[16][4]
Potassium (K)
Chloride (Cl)
2.1,
Total calcium (Ca)
Transferrin
Transferrin saturation
Ferritin - Male
Ferritin - Female
Phosphate (HPO42)
Inorganic phosphorus (serum)
Copper (Cu)
Zinc (Zn)
Magnesium
2.8
mmol/L
mg/dL
65,[18] 76[9]
176,[18] 198[9]
g/dL
11.6,[19][20] 13.6[20]
mol/L
26,[9] 50[18]
170[9][18]
g/dL
4.6,[20] 8.9[19]
30.4[19]
mol/L
100[18]
250[18]
g/dL
18[20]
45[20]
mol/L
[18]
120
[18]
g/dL
9[20]
21[20]
mol/L
240,[18] 262[9]
450,[18] 474[9]
g/dL
43,[20] 47[20]
81,[20] 85[20]
mol/L
mg/dL
25[22]
45[22]
mol/L
20[18]
50[18]
12[23]
300[23]
ng/mL
27[24]
670[24]
pmol/L
12[23]
150[23]
ng/mL
27[24]
330[24]
pmol/L
10,[25] 20[26]
35,[25] 65[26]
17,
Ceruloplasmin
2.6,
mg/dL
[8]
10.2,[8] 10.5[17]
Ammonia
Copper
2.5,
[16]
8.4,[8] 8.5[17]
50
Total serum iron (TSI) - children
2.2
[4]
[27]
34
[27]
60,
[27]
110
See hypokalemia
or hyperkalemia
mol/L
[27]
g/dL
70[17]
150[17]
g/dL
11[28]
24[28]
mol/L
15[17]
60[17]
mg/dL
1[29]
4[29]
mol/L
0.8
1.5[30]
mmol/L
1.0[8]
1.5[8]
mmol/L
3.0[8]
4.5[8]
mg/dL
11[31]
24
mol/L
60,[32] 72[33]
110,[33] 130[32]
g/dL
9.2,[34] 11[4]
17,[4] 20[34]
mol/L
1.5,[17] 1.7[35]
2.0,[17] 2.3[35]
mEq/L or mg/dL
0.6,[36] 0.7[4]
0.82,[36] 0.95[4]
mmol/L
Arterial/Venous
Lower limit
Upper limit
Arterial
7.34,[9] 7.35[8]
7.44,[9] 7.45[8]
Venous
7.31[38]
7.41[38]
36[8]
44[8]
nmol/L
3.6[39]
4.4[39]
ng/dL
pH
[H+]
Base excess
Arterial
Arterial & venous
Arterial pO2
[38]
-3
[38]
+3
[38]
mEq/L
10,[8] 11[40]
13,[40] 14[8]
kPa
75,[8][9] 83[17]
100,[9] 105[8]
mmHg or torr
4.0[40]
5.3[40]
kPa
30[38]
40[38]
mmHg or torr
Arterial
Venous
Approximately 75[12]
Oxygen saturation
Unit
Comments
4.4,[8] 4.7[40]
5.9,[8] 6.0[40]
kPa
44,[8] 45[9]
mmHg or torr
5.5[40]
6.8[40]
kPa
41[38]
51[38]
mmHg or torr
23[38]
30[38]
mmol/L
100[41]
132[41]
mg/dL
18[17]
23[17]
mmol/L
110[42]
140[42]
mg/dL
21, 22[8]
27, 28[8]
mmol/L or mEq/L[8]
Arterial PaCO2
33,
Carbon dioxide partial pressure (PCO2)
Venous
Bicarbonate (HCO3-)
[8]
35
[9]
[42]
170
[42]
mg/dL
Liver function
Further information: Liver function tests
Test
Patient type
Total Protein
Albumin
Globulins
Lower limit
Upper limit
Unit
Comments
60,[8] 63[9]
g/L
see hypoproteinemia
35[8][43]
48,[9] 55[8]
g/L
see hypoalbuminemia
3.5[9]
4.8,[9] 5.5[8]
U/L
540[44]
740[44]
mol/L
23[8]
35[8]
1.7,
Total Bilirubin
Male
2, 3.4,
[45]
[4]
mg/dL
U/L
0.15[4]
0.75[4]
[4]
1.1
kat/L
[4]
34[48]
IU/L
0.60[4]
kat/L
8[48]
40[48]
IU/L
0.25[4]
0.75[4]
kat/L
0.25
[4]
[47]
Female
42
Male
53[47]
98[47]
U/L
128[47]
[4]
1.8
5,[47] 8[9]
[4]
kat/L
40,[47] 78[9]
U/L
Women
0.63[49]
kat/L
Men
0.92[49]
kat/L
Cardiac tests
Test
[50]
38,
[9]
60
Upper limit
[47]
174,
[17]
320
[47]
200
[47]
male
0.42
[51]
1.5
[51]
Unit
U/L
or ng/mL
kat/L
[50]
38,
[9]
96
[17]
140,
[17]
female
0.17[51]
CK-MB
1.17[51]
3,
[52]
Female
Male
17[52]
Myoglobin
[9]
66
3.8,
U/L
or ng/mL
kat/L
[4]
[47]
ng/mL or g/L[4]
[52]
106[52]
ng/mL or g/L
Cutoffs and ranges for troponin types, 12 hrs after onset of pain
Test
Lower limit
0.2[53]
1.0[53]
[54]
2.0[54]
0.4
1.0,
[53]
1.5
[55]
Troponin-T 0.02[53]
0.10[53]
n/a
[53][55]
0.02[53]
0.10[53]
n/a[53]
Range / Cutoff
100-500 pg/mL[56][57]
>500 pg/mL[56][57]
NT-proBNP
Comments
0.2[53]
Troponin-I
mol/L
mol/L
25
0.3,[8][9] 0.4[17]
Female
22,
[4]
5,[8] 7[45][4]
[8][9]
6[48]
Male
g/L
[45]
0.0[8] or N/A[4]
0.15
Aspartate transaminase(AST/ASAT[4])
17,
[8][45]
Female
[8]
0.1,[8] 0.2,[9]0.29[46]
Direct/Conjugated Bilirubin
Alanine transaminase(ALT/ALAT[4])
[45]
Comments
Also called
serum glutamic oxaloacetic
transaminase(SGOT)
Age
Cutoff
Lipids
Further information: Blood lipids
Test
Patient type
10 39 years
Triglycerides
40 59 years
> 60 years
Total cholesterol
HDL cholesterol
HDL cholesterol
female
male
Lower limit
Upper limit
Unit
54[17]
110[17]
mg/dL
0.61[59]
1.2[59]
mmol/L
[17]
150[17]
mg/dL
0.77[59]
1.7[59]
mmol/L
80[17]
150[17]
mg/dL
0.9[59]
1.7[59]
mmol/L
3.0,[60] 3.6[8][60]
5.0,[4][61] 6.5[8]
mmol/L
< 3.9[58]
120,[9] 140[8]
200,[9] 250[8]
mg/dL
< 150[58]
70
mmol/L
40,[63] 50[65]
86[63]
mg/dL
0.9[62][4]
2.0[62]
mmol/L
80[63]
mg/dL
35[63]
2.0,
LDL cholesterol
(Not valid when
triglycerides >5.0 mmol/L)
80,
LDL/HDL quotient
Therapeutic target
[62]
[63]
2.4
94
[61]
[63]
120,
n/a
[63]
130
[63]
[4]
< 2.5[62]
< 100[63]
mg/dL
(unitless)
Tumour markers
Further information: Tumour markers
Test
Cutoff
Unit
Comments
44[9]
ng/mL or g/L
IU/l or mU/ml
U/ml
Pancreatic cancer
40[9]
CA-125
4.1[68]
g/l
[69]
g/l
2.5,[4] 4[9]
g/L[9][4] or ng/mL[17]
[17]
PAP
Calcitonin
-more detailed cutoffs in Calcitonin article
5,[70] 15[70]
ng/L or pg/mL
Endocrinology
Thyroid hormones
Further information: Thyroid function tests
Test
Patient type
0.3,[72] 0.5[73]
2.0,[73] 3.0[72]
mIU/L or IU/mL
Infants
1.3[74]
19[74]
mIU/L or IU/mL
0.7,[75] 0.8[9]
18,[4][77] 23[79]
0.4,
[9]
Child/Adolescent 0.8
31 d - 18 y
10[77]
Normal adult
Free triiodothyronine (FT3)
Children 2-16 y
Thyroglobulin (Tg)
[4]
[75]
Total thyroxine
Unit
Pregnant
Total triiodothyronine
Upper limit
0.3,
Normal adult
Free thyroxine (FT4)
-more detailed ranges in
Thyroid function tests article
Lower limit
0.5,
[17]
0.6
[71]
4.0,
2.0
[4]
4.5,
[9]
6.0
[75]
[17]
mIU/L or IU/mL
pmol/L
ng/dL
26[77]
pmol/L
0.5[75]
1.0[75]
ng/dL
6.5[77]
13[77]
pmol/L
4,[78] 5.5[9]
11,[78] 12.3[9]
g/dL
60[78][79]
140,[78] 160[79]
nmol/L
0.2[78]
0.5[78]
ng/dL
3.1[80]
7.7[80]
pmol/L
0.1[81]
0.6[81]
ng/dL
1.5[80]
9.2[80]
pmol/L
60,[9] 75[78]
175,[78] 181[9]
ng/dL
0.9,[4] 1.1[78]
2.5,[4] 2.7[78]
nmol/L
12[9]
30[9]
mg/L
1.5[78]
30[78]
pmol/L
1[78]
20[78]
g/L
Sex hormones
Levels of estradiol (the main estrogen), progesterone,luteinizing hormone andfollicle-stimulating hormoneduring the menstrual cycle.[82]
The diagrams at right take inter-cycle and inter-woman variability into account in displaying reference ranges for estradiol, progesterone, FSH and LH.[82]
Test
Dihydrotestosterone
Patient type
Lower limit
Upper limit
30[83]
adult male
8,[84] 10[85]
Male, overall
230,
[86]
300
[87]
ng/dL
27,[84] 35[85]
nmol/L
10[4]
45[4]
nmol/L
1300[86]
ng/dL
6.2[4]
26[4]
nmol/L
180[86]
740[86]
ng/dL
0.7[85]
2.8[85] - 3.0[4]
nmol/L
20[87]
80[87] - 85[86]
ng/dL
0.06[17]
3.0[17]
mg/L
0.18[88]
9.1[88]
mol/l
0.2[17]
1.0[17]
mg/L
0.6[88]
3.0[88]
mol/l
Prepubertal
<1[89]
3[89]
Adult male
1[89]
8[89]
1[89]
11[89]
6[89]
26[89]
95% PI (standard)
95% PI)
5[90]
15[90]
Female
male
17-Hydroxyprogesterone
Female (Follicular phase)
Follicle-stimulating
hormone (FSH)
-more detailed menstrual cycle
ranges in separate diagram
Unit
85[83]
[86]
IU/L
Post-menopausal female
30[89]
118[89]
Female, peak
20[90]
75[90]
Female, post-menopausal
15[91]
60[91]
[92]
[92]
50[93]
200[93]
pmol/L
55[94]
pg/mL
70[93]
500,[93]600[93]
pmol/L
19[94]
140,[94]160[94]
pg/mL
0.5[95]
9[95]
pg/mL
1.7[95]
33[95]
pmol/L
N/A[93]
< 130[93]
pmol/L
N/A[94]
< 35[94]
pg/mL
17,[90] 35[96]
92[96]
nmol/L
Adult male
14
Estradiol
(an estrogen)
-more detailed ranges in
estradiol article
Post-menopausal female
Progesterone
-more detailed ranges
in Progesterone article
Androstenedione
Anti-Mllerian hormone(AMH)
-more detailed ranges in
AMH article
[90]
11
[97]
29
< 180[91]
Prepubertal
< 60[91]
Adult female
Adult male
30[98]
400[98]
40[99]
120[99]
20
1345 years
[99]
60[99]
Patient type
ng/mL
140[101]
pmol/l
Upper limit
Unit
18,[103] 22[102]
pmol/L
20[9]
80,[104] 100[9]
pg/mL
700
[105]
nmol/L
5[106]
25[106]
g/dL
80[105]
350[105]
nmol/L
2.9[106]
13[106]
g/dL
5[8]
ng/mL
7[8]
n/a
ng/mL
Cortisol
Midnight
420[107]
220[107]
Male, 20 yrs
160
[107]
nmol/L
5[101]
4.4[102]
140
09:00 am
g/dL
20[100]
Lower limit
[105]
ng/dL
0.7[100]
ng/mL
270[91]
Other hormones
IGF-1
-more detailed ranges in
IGF-1 article
[97]
Post-menopausal female
Dehydroepiandrosterone sulfate
-more detailed ranges
Adult male and female
in DHEA-S article
SHBG
-more detailed ranges
in SHBG article
[94]
60[91]
IU/L
390
[107]
ng/mL
48[107]
Male, 75 yrs
71,
Prolactin
-more detailed ranges in
Prolactin article
200[107]
[108]
Female
3.4,
105
[108]
3.9
[108]
348,[108] 548[108]
[108]
58,[108] 89[108]
Male
2.7,
[108]
3.3
277,[108] 365[108]
[108]
65,[109] 70[110]
pg/mL
[111]
6.9,[4] 7.5[111]
pmol/L
8,[17][112] 9[112]
40,[112] 80[17]
ng/mL
20,[113] 23[114]
95,[114] 150[113]
nmol/L
30,[115] 40[116]
65,[116] 100[115]
ng/mL
85,[58] 100[116]
120,[58] 160[116]
nmol/L
1.1,
25-hydroxycholecalciferol
-Therapeutic target range
mIU/L
10,[109] 17[110]
Parathyroid hormone (PTH)
25-hydroxycholecalciferol (a vitamin D)
-Standard reference range
mIU/L
[4]
1.8
ng/(mL*hour)
3.3,[119] 21[120]
mcU/mL
41[119][120]
19,[119] 34.0[119]
Adult
530,
[121]
940
[121]
ng/dL
pmol/L
360,[122] 970[122]
Vitamins
Also including the vitamin B12)-related amino acid homocysteine.
Standard range
Test
Optimal range
Patient type
Unit
Lower limit
Vitamin A
30
Vitamin B9
(Folic acid/Folate) - Serum
Upper limit
[17]
65
3.0[123]
16[123]
[125]
[125]
200
36
[123]
600
450[125]
Vitamin B9
(Folic acid/Folate) - Red blood cells
Lower limit
[17]
Upper limit
g/dL
ng/mL or g/L 5[124]
11[125]
nmol/l
[123]
ng/mL or g/L
1400[125]
nmol/L
ng/mL or g/L 400[123]
Pregnant
900[123]
nmol/L
130,
Vitamin B12 (Cobalamin)
Homocysteine
-more detailed ranges in
Homocysteine article
[126]
160
[127]
700,
[126]
950
[127]
ng/L
100,[128] 120[4]
520,[128] 700[4]
pmol/L
3.3,[129] 5.9[129]
7.2,[129]15.3[129]
mol/L
6.3[58]
g/dL
85[58]
45,
[130]
80
[130]
100,
[130]
0.4[17]
1.5[17]
[131]
[131]
85
[17][112]
25-hydroxycholecalciferol (a vitamin D)
20,
[113]
[112]
23
[114]
40,
[112]
95,
[114]
210
80
[130]
[17]
150
[113]
mg/dL
0.9[58]
mol/L
50[58]
ng/mL
nmol/L
mol/L
28[58]
mg/dL
1.2[58]
Vitamin E
Toxins
Test
Limit type
Limit
Unit
Lead
g/dL
17.4[133]
mmol/L
Hematology
Red blood cells
These values (except Hemoglobin in plasma) are for total blood and not only blood plasma.
Test
Patient
male
Hemoglobin (Hb)
Lower limit
Upper limit
Unit
2.0,[134]2.1[135][8]
2.5,[134]2.7[135][8]
mmol/L
130,[4] 132,[9]135[8]
162,[9] 170,[4]175[8]
g/L
1.8,[134]1.9[135][8]
2.3,[134]2.5[8][135][134]
mmol/L
150,[4] 152,[9]160[8][17]
g/L
mmol/L
female
120
Hemoglobin subunits (sometimes displayed
simply as "Hemoglobin")
male
female
[4][8][9]
8.0,[136] 8.4[136]
7.2,
[136]
7.6
10.0,[136]10.8[136]
[136]
9.2,[136] 10.0[136]
0.16[8]
0.62[8]
mol/L
mg/dL
Hemoglobin in plasma
< 50 years
3.6[4]
5.0[4]
> 50 years
[4]
5.3[4]
[4]
< 50 years
0.35
> 50 years
0.47[4]
Haptoglobin
[4]
1.9
0.4, 0.41,
[8]
male
0.39,
female
0.35,[4] 0.36,[8]0.37[9][17]
Hematocrit (Hct)
% of Hb
[4]
g/L
2.1[4]
[9]
Comments
0.45
[17]
0.50,
[4]
[9]
0.52, 0.53,
0.46,[8][9][4]0.48[17]
[8]
0.62
[17]
0.31[9]
Child
Male
76,
78
[17]
82
[9]
0.54[8]
fmol/cell
[9]
32
32,[17] 33,[4]35[8]
[17][4]
35,
4.8,[137] 5.0[137]
[17]
4.3
36
Female
3.5,[8] 3.8,[9]3.9[4]
g/dL
or %[note 1]
mmol/L
5.1,[4] 5.5[8][9]
Infant/Child 3.8[9]
5.5[9]
[4]
130[4]
[8][9]
1.5
x1012/L
or
mln/mm3
x109/L
[8][9]
Adult
0.5
Newborn
1.1[9]
4.5[9]
% of RBC
Infant
0.5[9]
3.1[9]
% of RBC
Reticulocytes
pg/cell
[17][4]
4.2,
26
[9]
5.4,[137] 5.6[137]
[8][9][4]
male
Adult
fL
14.5[9]
31,
fL
101[9]
[8]
25,[8] 27[17][4]
100,[17] 102[9]
11.5[9]
0.39
0.43[9]
[9]
% of RBC
Unit
Newborn
9[139]
30[139]
1 year old
6[139]
18[139]
1.3,
Adult
Neutrophil granulocytes
(A.K.A. grans, polys, PMNs, or segs)
Newborn
Neutrophilic band forms
Upper limit
Adult
Newborn
Monocytes
Newborn
Mononuclear leukocytes
(Lymphocytes + monocytes)
Adult
CD4+ cells
Adult
x103/L
9
x10 /L
% of WBC
0.7[139]
x109/L
[8]
[8]
% of WBC
0.7,[4] 1.0[138][139]
16-25[8]
33,[8] 45
% of WBC
11[139]
x109/L
0.1,[4] 0.2[140][126]
0.8[126][139][4]
x109/L
3,[8] 4.0
7,[8] 10
% of WBC
0.4[139]
3.1[139]
x109/L
1.5
x109/L
20
35
% of WBC
0.4,[9] 0.5[12]
1.5,[12] 1.8[9]
x109/L
0.0,[4] 0.04[126]
x109/L
[139]
[8]
3,
[8]
x109/L
% of WBC
0.02[139]
0.85[139]
x109/L
40[138]
x106/L
Adult
Basophil granulocytes
[139]
x109/L
1
Newborn
7,
[138]
26[139]
Adult
Eosinophil granulocytes
5.4,
[4]
6[139]
Adult
[139]
x103/mm3 or
62,[8] 74
3
Adult
1.8,
[138]
x109/L
45-54[8]
Adult
Lymphocytes
[4]
0.0
0.75,
[8]
% of WBC
0.64[139]
Newborn
x109/L
Coagulation
Test
Lower limit
140,
[9]
150
Upper limit
[8][4]
[141]
350,
[17][4]
10.4
[141]
Unit
[8]
400, 450
[9]
Comments
x109/L or
x1000/L
7.4
fL
PT reference varies between laboratory kits - INR is standardised
INR
0.9[4]
1.2[4]
11
18
Fibrinogen
1.7,[9] 2.0[4]
3.6,[4] 4.2[9]
g/L
Antithrombin
0.80[4]
1.2[4]
kIU/L
Bleeding time
minutes
Viscosity
1.5[143]
1.72[143]
cP
Immunology
Acute phase proteins
Acute phase proteins are markers of inflammation.
Test
Age2[144]
5,
n/a
(Age+10)2[144]
[146][4]
[147]
Unit
Comments
mm/hr
mg/L
200,[148]240[148] nmol/L
20,
[149]
89,
[151]
22
[150]
38,[150] 53[149]
mol/L
[4]
170,[4] 230[151]
mg/dL
97
Isotypes of antibodies
Further information: Antibody
Test Patient Lower limit
Upper limit
Unit
IgA
IgD
0.5[152]
IgE
Adult
0.01
[152]
[152]
IgG
800
IgM
54[152]
Comments
3.0[152]
0.04[152]
mg/dL
1800[152]
220[152]
Autoantibodies
For clinical associations, see Autoantibody.
Autoantibodies are usually absent or very low, so instead of being given in standard reference ranges, the values usually denote where they are said to be present, or whether
the test is a positive test. There may also be an equivocal interval, where it is uncertain whether there is a significantly increased level. All included values [153] are given for
the ELISA test.
Test
anti-SS-A (Ro)
< 15[154]
anti-SS-B (La)
<3
Anti ds-DNA
< 40
Anti ss-DNA
<8
15-25[154]
[154]
34
[154]
40 60
[154]
8 - 10
[154]
Anti-histone antibodies
< 25
Cytoplasmic/classical
anti-neutrophil cytoplasmic
antibodies (c-ANCA)
< 20[154]
Perinuclear
anti-neutrophil cytoplasmic
antibodies (p-ANCA)
< 5[154]
> 25[154]
[154]
> 4[154]
[154]
> 60[154]
[154]
> 10
[154]
[154]
> 25[154]
21 - 30[154]
> 30[154]
n/a
Units
per
millilitre
(U/mL)
n/a
> 5[154]
n/a[154]
> 10[154]
20 - 30
> 30[9]
< 20
Antistreptolysin O titre
(ASOT) in
preschoolers
> 100
> 250[9]
ASOT in adults
> 125[9]
Test
Anti-phospholipid IgG
< 20[154]
Anti-phospholipid IgM
< 1.5
Anti-phospholipid IgA
< 10
20 30[154]
[154]
1.5 2.5
[154]
10 -20
31 50[154]
[154]
2 9.9
[154]
21 30
20 39[154]
> 51[154]
[154]
[154]
40 - 59[154]
GPLU/ml[154]
> 10
[154]
MPL /ml[154]
> 31
[154]
arb U/ml[154]
> 60[154]
EU[154]
Amylase
D-dimer
Lower limit
Upper limit
Unit
50[17]
150[17]
U/L
0.4[47]
1.7[47]
mol/L
1.8
[4]
25,
[8]
3.4
30,
[9]
53
[17]
[4]
110,
[9]
kat/L
120,
[155]
123,
[17]
[8]
125, 190
[47]
1.1[4]
kat/L
200[148]
240[148]
nmol/L
500[156]
ng/mL
0.5[4]
mg/L
Lipase
57[47]
U/L
Acid phosphatase
3.0[47]
ng/mL
16[4]
g/L
2.3[4]
[4]
U/L
U/L
0.15[4]
n/a
Comments
Upper limit
Unit
Comments
Osmolality
Osmolarity
mOsm/l
3.0[158]
7.0[158]
mmol/L
7[8]
18,[8] 21[9]
mg/dL
Urea
0.18[8]
* Uric acid
Creatinine
[9]
0.48[8]
mmol/L
Female
2.0
[17]
7.0[17]
mg/dL
Male
2.1[17]
8.5[17]
mg/dL
60,[4] 68[159]
90,[4] 118[159]
mol/L
0.7,[160] 0.8[160]
1.0,[160] 1.3[160]
mg/dL
male
50,[4] 68[159]
90,[4] 98[159]
mol/L
1.0,[160] 1.1[160]
mg/dL
5[17]
35[17]
3.8,[8] 4.0[4]
6.0,[4] 6.1[161]
mmol/L
100,[161] 110[17]
mg/dL
3.3[4]
female
0.6,
BUN/Creatinine Ratio
Plasma glucose(fasting)
Pyruvate
5.6[4]
mmol/L
100[162]
mg/dL
4.5[17]
19.8[17]
mg/dL
0.5[163]
2.2[163]
mmol/L
4.5[17]
14.4[17]
mg/dL
0.5[163]
1.6[163]
mmol/L
300[17]
900[17]
g/dL
34[164]
102[164]
mol/L
60
Lactate (Arterial)
0.8
[160]
[162]
Lactate (Venous)
[160]