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Clot line
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Introduction
Haemostasys analysis
HAEMOSTASIS analysis and specially the PLASMATIC PHASE has deserved special attention in RAL since its foundation in 1980, it was and still is a priority field. On January 1969 we began with the presentation of Fibrometer, an instrument with mechanical detection of the clot, that was the first step to automatisation. Later, on 1973 we presented the Digiclot Elvi 818 coagulometer with optical detection of the Clot formation that, together with Biodynamics, were the up-dated newness technology. Thanks to the unconditional support of some people that well know this field, we began on April 1976 the publication of short divulge notebooks to our customers under the name of TEMAS DE HEMOSTASIA (Haemostasis themes). These publications were given to the interested people, till June 1979. Simultaneously, during this period, we have done a lot of presentations in the main Spanish cities, generally supported by the local analysts associations, presenting the new technology and the practice of more advanced methods. At RALs foundation, we agreed as priority to follow the initial work and spend in R+D to get our own product line, with high quality to cover the needs of the most demanding customers, and we still work in this direction. Now, and after instruments as TURBICLOT, STIRR CLOT 2000 and CLOT 1 A, we are focusing our line on CLOTTY, CLOT SP, CLOT 2 B and AUTOCLOT.
Today we offer a whole service for the HAEMOSTASIS PLASMATIC PHASE analysis, based on an instrument line and complementary reagents too.
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Description
Short description of plasmatic haemostasis phase
Haemostasis cascade
Instruments
1 2 3 4
Placement of cuvette in measuring cell. Reset the chronometer. Addition of starter reagent (or plasma). Security time (5 seconds). Fibrin polymers formation (clot).
PRINCIPLE OF WORK
3 5
Clotting time.
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Clotty
One channel coagulometer
One channel coagulometer for automatic detection of Clot formation by turbodensitometric principle. Easy to use and program, including calibration curves. Microprocessor built-in-it. Sequential results obtainment.
Clot 2B
Dual channel coagulometer
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Clot SP
One channel coagulometer
One channel coagulometer for automatic detection of Clot formation by turbodensitometric principle. Memory capacity for 10 test. Easy to use and program, including calibration curves. Printer built-in-it. Two models: macro and microcuvettes.
Dual channel coagulometer for automatic detection of fibrin formation, under turbodensitometer principle. Consecutive or dupplicate measurements. Easy to program, with a capacity of 10 stored methods. Automatic optical start and stop system. Mixing procedure during test development, to well homogenise sample and reagent, and help to detect weak clots. Possibility to introduce the activity curve obtained by using a pool of normal local patients plasmas. Calibration curve for Fibrinogen tests. Deficiency plasmas factors can be studied too. Two models: macro and microcuvettes.
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Autoclot
Automatic coagulometer
Turbodensitometric detection principle with LED technology. Automatic analysis and calculation of PT, APTT, Fibrinogen, TT and factor studies. Automatic calibration of PT and Fibrinogen with calibrator and samples automatic dilution, when needed. Samples are automatically rerun when results do not fit the programmed range. Rotor capacity for 32 samples and 32 reaction cuvettes. Reagents compartment for 6 vials. Washing and deproteinizant compartment. Probe with level detection. Throughput: 50 PT or Fibrinogen per hour. 25 APTT per hour. Macro and microcuvettes.
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Reagents
1 Quick test- PT
GN 1015 GN 1011 HEMOPLASTIN L HEMOPLASTIN L ISI 1.0-1.3 ISI 1.0-1.3 6 x 5 ml 6 x 10 ml
2 APTT test
GN 1033 GN 1030 GN 1031 GN 1080 GN 1060 GN 1081 HEMOS PTT KIT 3 + 3 x 4 ml Ellagic Acid + Calcium chloride HEMOS PTT KIT 3 + 3 x 10 ml Ellagic Acid + Calcium chloride HEMOSPTT - Ellagic Acid 6 x 4 ml Calcium chloride 6 x 4 ml HEMOSPTT - Ellagic Acid 6 x 10 ml Calcium chloride 6 x 10 ml
3 Fibrinogen test
GN 1045 GN 1145 HEMOFIBRIN 5 x 2 ml + 125ml + 1ml Bovine Thrombin + Imidazole Buffer + Calibrator HEMOFIBRIN L 5 x 2 ml + 125ml + 1ml Bovine Thrombin + Imidazole Buffer + Calibrator
4 Control plasmas
GN 1100 GN 1200 HEMOTROL N HEMOTROL P 6 x 1 ml 6 x 1 ml
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Av. Mare de Du de Montserrat, 51 - 08970 Sant Joan Desp - Barcelona - Spain Tel. (+34) 93 480 80 47 - Fax (+34) 93 373 00 92 - e-mail: ral@ral-sa.com - www.ral-sa.com