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Flashcard Set Title: "Goljan Rapid Review Images"

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Mallory bodies. Hyaline (eosinophilic) inclusions (arrow) are present in the cytosol of hepatocytes.

A and B, Right-sided Bell's palsy showing inability to fully close the eye and drooping of the corner of the mouth

Acid-fast stain of a lung biopsy in a patient with reactivation tuberculosis due to Mycobacterium tuberculosis

Acoustic neuroma showing spindleshaped cells with alternating dark and light areas

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Flashcard Set Title: "Goljan Rapid Review Images"


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Bronchopneumonia showing patchy areas of consolidation

Cerebellum in a patient with rabies showing Purkinje cells with intracytoplasmic, eosinophilic inclusions (arrows) called Negri bodies

Common systemic fungal infections. The yeast form of Cryptococcus neoformans (A) produces a narrow-based bud (arrow). Coccidioides immitis (B) has spherules containing endospores (arrows). Multinucleated giant cells

Dependent pitting edema showing depressions in the skin around the ankle. Pitting edema is due to an increase in vascular hydrostatic pressure or a decrease in vascular oncotic pressure (hypoalbuminemia)

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Flashcard Set Title: "Goljan Rapid Review Images"


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Dermatographism

Diffuse membranous glomerulonephritis. The H[amp ]E (hematoxylin [amp ] eosin)-stained biopsy (A) shows glomerular basement membranes that are uniformly thickened. There is no proliferative component. The silver stain

Diffuse type of gastric adenocarcinoma with signet-ring carcinoma cells (arrows)

Electron micrograph of a type II pneumocyte showing lamellar body (arrow) containing surfactant

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Flashcard Set Title: "Goljan Rapid Review Images"


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Embryonated eggs of Enterobius vermicularis

Metastatic renal cell carcinoma showing multiple nodular lesions scattered throughout the lung parenchyma

Fibroadenoma

Mallory bodies. Hyaline (eosinophilic) inclusions (arrow) are present in the cytosol of hepatocytes

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Flashcard Set Title: "Goljan Rapid Review Images"


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Fatty change of the liver

Hydronephrosis of the kidney. There is marked dilation of the renal pelvis and calyces with thinning of the overlying cortex and medulla due to compression atrophy

. Left ventricular hypertrophy

.Benign prostatic hyperplasia

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Flashcard Set Title: "Goljan Rapid Review Images"


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Intestinal metaplasia of the gastric mucosal epithelium in chronic gastritis

Squamous dysplasia of the cervix, a precursor of squamous cell carcinoma..jpg

Acute myocardial infarction (MI) showing coagulation necrosis.

Acute myocardial infarction (MI) showing a pale infarction of the posterior wall of the left ventricle (bottom left)

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Flashcard Set Title: "Goljan Rapid Review Images"


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Hemorrhagic infarction of the lung. There is a roughly wedge-shaped area of hemorrhage.jpg

Dry gangrene of the toes

Cerebral infarction showing liquefactive necrosis

Caseous granuloma showing a central area of acellular, necrotic material surrounded by activated macrophages (epithelioid cells), lymphocytes, and multiple multinucleated Langhans-type giant cells

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Flashcard Set Title: "Goljan Rapid Review Images"


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Enzymatic fat necrosis in acute pancreatitis

Apoptosis in the epidermis. The arrow shows a clear space in the epidermis containing an intensely eosinophilic staining cell with a small, dense nucleus.

Signs of acute inflammation. The patient has erysipelas of the face due to group A streptococcus. Signs of acute inflammation that are present in the photograph include redness (rubor) and swelling (tumor)

Acute inflammation. Histologic section of lung in bronchopneumonia showing sheets of neutrophils with multilobed nuclei.

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Flashcard Set Title: "Goljan Rapid Review Images"


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Purulent (suppurative) inflammation. The photograph shows a skin abscess (furuncle) due to Staphylococcus aureus. Abscesses are pus-filled nodules located in the dermis.

Fibrinous inflammation. The epicardial surface of the heart is covered by a shaggy layer of fibrin material

Pseudomembranous inflammation. There is necrosis and a yellow-colored exudate covering the mucosal surface of the colon due to a toxin produced by Clostridium difficile.

Chronic inflammation. This tissue shows an infiltrate of predominantly plasma cells (cells with eccentric nucleus and perinuclear clearing) and lymphocytes

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Flashcard Set Title: "Goljan Rapid Review Images"


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Ehlers-Danlos syndrome

Keloid formation

Absolute leukocytosis with left shift. Arrows point to band (stab) neutrophils, which exhibit prominence of the azurophilic granules (toxic granulation). Vacuoles in the cytoplasm represent phagolysosomes

Malar rash in systemic lupus erythematosus showing the butterfly-wing distribution

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Flashcard Set Title: "Goljan Rapid Review Images"


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Systemic sclerosis. The tightening of the skin around the mouth is caused by excess collagen.

Kaposi's sarcoma in HIV. Skin lesions are raised, red, and nonpruritic

Patient with signs of volume the mucosal surface of the tongue is dry. Additional findings on examination were hypotension, tachycardia, and decreased skin turgor. (From Forbes C, depletion

Electrocardiogram showing hyperkalemia. Arrows show peaked T waves, which are a sign of hyperkalemia.

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Flashcard Set Title: "Goljan Rapid Review Images"


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Coronary artery thrombosis. In this specially stained cross-section of a coronary artery, collagen is blue and the thrombus is red

Pulmonary embolus. The main branches of the pulmonary artery are occluded with large-caliber thromboemboli (saddle emboli)

Down syndrome. The facial profile (A) shows a short stature, small head with small nose and ears. The hand (B) shows a single palmar (simian) crease

Turner's syndrome is characterized by a webbed neck

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Flashcard Set Title: "Goljan Rapid Review Images"


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Klinefelter's syndrome

Prader-Willi syndrome

Angelman syndrome

Testicular feminization. The patient is genotypically male, but phenotypically female

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Flashcard Set Title: "Goljan Rapid Review Images"


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Black widow spider

Brown recluse spider

Kwashiorkor and marasmus. Left, Child with kwashiorkor, showing dependent pitting edema involving the lower legs. Right, Child with marasmus, showing broomstick extremities with loss of muscle mass and sub

Anorexia nervosa

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Flashcard Set Title: "Goljan Rapid Review Images"


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Gums showing the effects of scurvy

Tubular adenoma (adenomatous polyp) of the colon showing a fibrovascular stalk

Lipoma showing a wellcircumscribed yellow tumor (A) containing benign adipose cells (B)

Cystic teratoma of the ovary,

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Flashcard Set Title: "Goljan Rapid Review Images"


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.Figure 8-4 Squamous cell carcinoma. The many well-differentiated foci of eosinophilic-staining neoplastic cells produce keratin in layers (keratin pearls)..jpg

Adenocarcinoma. Irregular glands infiltrate the stroma

Osteogenic sarcoma of the distal femur. The light-colored mass of tumor in the metaphysis abuts the epiphyseal plate (arrow)

Metastasis to the liver. The liver contains multiple nodules that have a depressed central area (umbilicated)

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Flashcard Set Title: "Goljan Rapid Review Images"


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Basal cell carcinoma (invasive tumor that does not metastasize)

Malignant melanoma. The lesion on the patient's forearm is black, is multinodular, and has an irregular border with areas of pale-gray discoloration

Xanthelasma. Yellow, raised lesions are noted on the eyelids in both eyes

Hyaline arteriolosclerosis

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Flashcard Set Title: "Goljan Rapid Review Images"


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Abdominal aortic aneurysm

Henoch-Schnlein purpura

Acute myocardial infarction (day 7) in the posterior wall of the left ventricle

Fibrinous pericarditis. The surface of the heart is covered by a shaggy, fibrinous exudate

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Flashcard Set Title: "Goljan Rapid Review Images"


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Left ventricular aneurysm. The bulging aneurysm has a thin wall of scar tissue

Acute rheumatic fever. Uniform, verrucoid-appearing sterile vegetations appear along the line of closure of the mitral valve

Mitral valve prolapse. The arrow shows prolapse of the posterior mitral leaflet into the left atrium

Aortic stenosis

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Flashcard Set Title: "Goljan Rapid Review Images"


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Acute bacterial endocarditis

Myocarditis. The biopsy shows a lymphocytic infiltrate with dissolution of myocardial fibers

Peripheral blood reticulocytes with supravital stain (new methylene blueView drug information). Red blood cells with thread-like material in the cytosol represent residual RNA filaments and protein (arrow

Peripheral blood smear in iron deficiency anemia. The enlarged central area of pallor in the red blood cell (arrow) indicates a decrease in hemoglobin synthesis,

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Flashcard Set Title: "Goljan Rapid Review Images"


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Ringed sideroblasts in a bone marrow aspirate. Dark blue iron granules around the nucleus of developing normoblasts (arrows) represent iron trapped within mitochondria and indicate a defect in mitochondri

Peripheral blood with coarse basophilic stippling of RBCs in lead poisoning. Note the mature RBC containing numerous dots representing ribosomes (arrow)

Peripheral blood in megaloblastic anemia showing the hypersegmented neutrophil (arrow) with nine lobes

Peripheral blood with spherocytes in hereditary spherocytosis. Numerous, round, dense red blood cells (RBCs) without central areas of pallor represent spherocytes (arrows). The mean corpuscular hemoglobi

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Flashcard Set Title: "Goljan Rapid Review Images"


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Peripheral blood with sickle cells and target cells, showing the dense, boat-shaped sickle cells. Cells with a bull's-eye appearance are target cells (arrows), which have excess RBC membrane that bulges

Peripheral blood with sickle cells and HowellJolly bodies. The three dense boat-shaped sickle cells and the two cells containing a single dark, round inclusion (arrows) represent nuclear remnants. Howel

Peripheral blood with schistocytes. The fragmented red blood cells (RBCs) with absence of central pallor, schistocytes, are produced when RBCs are mechanically injured by calcium deposits in an aortic valve

Plasmodium falciparum ring forms in red blood cells (RBCs). This RBC has two ring forms. Multiple infestation of an RBC is characteristic of P. falciparum malaria

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Flashcard Set Title: "Goljan Rapid Review Images"


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Leukoerythroblastic reaction. Numerous bone marrow reticulocytes with a blue discoloration

Peripheral blood with atypical lymphocyte. The cell shows prominent nucleoli and coarse nuclear chromatin. The cytoplasm is abundant and is indented by adjacent red blood cells

Peripheral blood in chronic myelogenous leukemia. Marked leukocytosis shows neutrophils at different stages of development (segmented and band neutrophils, metamyelocytes and myelocytes)

Peripheral blood with promyelocyte filled with Auer rods in acute promyelocytic leukemia

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Flashcard Set Title: "Goljan Rapid Review Images"


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Peripheral blood in chronic lymphocytic leukemia

Gaucher disease

Niemann-Pick disease

Senile purpura

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Flashcard Set Title: "Goljan Rapid Review Images"


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Laryngeal squamous cell carcinoma

Asbestos body

Malignant mesothelioma

Sarcoid granuloma

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Flashcard Set Title: "Goljan Rapid Review Images"


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Chest radiograph in emphysema

Primary lung cancer

Small cell carcinoma of the lung

Oral thrush

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Flashcard Set Title: "Goljan Rapid Review Images"


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Hairy leukoplakia along the lateral.

Leukoplakia of the tongue

.Barrett's esophagus

. Esophageal varices

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Flashcard Set Title: "Goljan Rapid Review Images"


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. Gastric adenocarcinoma

.Entamoeba histolytica trophozoites

. Celiac disease

.Dermatitis herpetiformis

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Flashcard Set Title: "Goljan Rapid Review Images"


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Hemorrhagic infarction

. Meckel diverticulum

. Sigmoid diverticulosis

. Ulcerative colitis.

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Flashcard Set Title: "Goljan Rapid Review Images"


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. Crohn's disease

Tubular adenoma

. Familial polyposis

. Acute appendicitis

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Flashcard Set Title: "Goljan Rapid Review Images"


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. Centrilobular hemorrhagic necrosis

Alcoholic cirrhosis

. Spider angioma (telangiectasia)

.Kayser-Fleischer ring.

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Flashcard Set Title: "Goljan Rapid Review Images"


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.Hepatocellular carcinoma

. Yellow cholesterol stones

.Black pigmented stones

. Adult polycystic kidney disease

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Flashcard Set Title: "Goljan Rapid Review Images"


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Normal glomerulus

.Subepithelial immunocomplex

.Red blood cell cast in the urine

. Crescentic glomerulonephritis

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Flashcard Set Title: "Goljan Rapid Review Images"


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. Fatty cast under polarization

. Diabetic glomerulosclerosis

.Acute pyelonephritis.

.Waxy cast in the urine sediment

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Flashcard Set Title: "Goljan Rapid Review Images"


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. Benign nephrosclerosis

.Renal cell carcinoma

Benign prostatic hyperplasia

.Prostate cancer. Arrow

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Flashcard Set Title: "Goljan Rapid Review Images"


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A, Candida. B, Chlamydia trachomatis. C, Gardnerella vaginalis. D, Herpes type E, Herpes type 2. F, Human papillomavirus.

G, Neisseria gonorrhoeae. H, Treponema pallidum. I, Treponema pallidum. J, Trichomonas vaginalis.

.Extramammary Paget's disease

.Squamous cell carcinoma of cervix

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Flashcard Set Title: "Goljan Rapid Review Images"


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.Polycystic ovarian syndrome

.Simple hyperplasia of endometria.jpg

. Endometrial carcinoma

.Leiomyomas.

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Flashcard Set Title: "Goljan Rapid Review Images"


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. Ruptured ectopic tubal pregnancy

.Complete hydatidiform mole

.Ductal carcinoma in situ (DCIS)

.Lobular carcinoma in situ

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Flashcard Set Title: "Goljan Rapid Review Images"


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.Infiltrating ductal carcinoma.

.Paget's disease of the breast

.Acromegaly showing the patient

. Primary hypothyroidism

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Flashcard Set Title: "Goljan Rapid Review Images"


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Graves' disease

Papillary carcinoma of thyroid.

.Patient with Cushing syndrome

.Osteoporosis of vertebral column

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Flashcard Set Title: "Goljan Rapid Review Images"


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.Rheumatoid arthritis

.Tophi (arrows)

.Erythema chronicum migrans

.Verruca vulgaris (common wart)

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Flashcard Set Title: "Goljan Rapid Review Images"


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.Molluscum contagiosum

.Erythema infectiosum

.Varicella infection of skin

Impetigo of the face

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Flashcard Set Title: "Goljan Rapid Review Images"


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. Patient with severe facial acne

.Acne rosacea

. Tinea versicolor.

. Lymphocutaneous sporotrichosis

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Flashcard Set Title: "Goljan Rapid Review Images"


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.Contact dermatitis.

.Actinic (solar) keratosis

Lichen planus showing flattopped

.Psoriasis involving the elbow

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Flashcard Set Title: "Goljan Rapid Review Images"


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.Nail changes in psoriasis

. Pityriasis rosea

. Erythema multiforme

. Erythema nodosum

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Flashcard Set Title: "Goljan Rapid Review Images"


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. Granuloma annulare.

. Acanthosis nigricans

.Solar lentigo

. Seborrheic keratosis on the breast

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Flashcard Set Title: "Goljan Rapid Review Images"


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. Compound nevus

.Lentigo maligna melanoma

.Anencephaly

. Neurofibromatosis

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Flashcard Set Title: "Goljan Rapid Review Images"


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.Epidural hematoma

.Subdural hematoma

.Atherosclerotic stroke.

.Embolic stroke

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Flashcard Set Title: "Goljan Rapid Review Images"


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. Intracerebral hemorrhage

.Bacterial meningitis

. Cerebral abscess

.Fusion of the podocytes. Arrowheads show fusion of the podocytes, which should be separated by slit pores. This finding occurs in all glomerular diseases that present with the nephrotic syndrome (e.g., minimal change

page 49 / 60

Flashcard Set Title: "Goljan Rapid Review Images"


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.Gram stain of Streptococcus pneumoniae. The sputum stain shows numerous lancet-shaped diplococci

.Granular immunofluorescence. Granular irregular deposits in the capillaries are caused by immunocomplex deposition (e.g., poststreptococcal glomerulonephritis

. brain of a newborn with kernicterus. Arrows depict yellow bilirubin pigment deposited in the basal ganglia

.Herpes zoster

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Flashcard Set Title: "Goljan Rapid Review Images"


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.Huntington disease. Coronal section (A) shows a dilated lateral ventricle and atrophy of the caudate, putamen, and globus pallidus when compared with a normal coronal section (B)

.If the crystal is blue when parallel to the slow ray, the crystal demonstrates positive birefringence.

.Normal peripheral blood smear showing RBCs. The RBCs are uniform in size, and the central areas of pallor are slightly less than half the total diameter of an RBC. The four dark objects (arrows) outside

. Giardia lamblia with two nuclei

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Flashcard Set Title: "Goljan Rapid Review Images"


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. Man with ankylosing spondylitis

.Keratoacanthoma

classic Reed-Sternberg (RS) cell. The large, multilobed cell with prominent nucleoli is surrounded by a halo of clear nucleoplasm. Classic RS cells are more easily found in mixedcellularity Hodgkin's lymphoma

.Linear immunofluorescence. The uninterrupted smooth immunofluorescence along the glomerular basement membrane is caused by deposition of IgG antibodies directed against the membrane (e.g., Goodpasture syndrome)

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Flashcard Set Title: "Goljan Rapid Review Images"


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.Liver biopsy stained with Prussian blue in a patient with hereditary hemochromatosis

.Lung biopsy stained with Gomori methenamine-silver showing septated hyphae and fruiting body (inset) of Aspergillus fumigatus

.Malignant plasma cells in multiple myeloma. The majority of malignant plasma cells show a gray-blue cytoplasm, peripherally located nuclei, and perinuclear clearing

.Multiple sclerosis showing multiple areas of demyelinated white matter (arrows pointing to brown plaques)

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Flashcard Set Title: "Goljan Rapid Review Images"


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analgesic nephropathy showing multiple brownish necrotic papillae (arrows)

.Neonatal respiratory distress syndrome

.Neurocysticercosis showing multiple cysts between the gray and white matter

.Optic disk with papilledema showing loss of the disk margin and hard exudates (white streaks

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Flashcard Set Title: "Goljan Rapid Review Images"


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.Osteoarthritis. Bony protuberances (Heberden's nodes)

.Patient with myasthenia gravis showing ptosis of the left eye (A) followed by opening of the eye (B) after intravenous injection of Tensilon.

.Petechiae in idiopathic thrombocytopenic purpura showing pinpoint hemorrhages, a sign of platelet dysfunction

.Pneumocystis jiroveci pneumonia. This silver-impregnated cytologic smear

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Flashcard Set Title: "Goljan Rapid Review Images"


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.Poststreptococcal diffuse proliferative glomerulonephritis

.Potassium hydroxide preparation of skin scrapings showing hyphae and yeasts

.Prostate cancer metastatic to the vertebral column. Multiple white foci of metastatic prostate cancer produce an osteoblastic response in the bone.

.Radiograph of a skull showing multiple punched out lytic lesions in multiple myeloma

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.Radiograph showing small bowel obstruction.

.Saddle embolus occluding the main branches of the pulmonary artery

.Senile plaque (arrow) shows an eosinophilic center with peripherally located distended neuronal processes (neurites).

.Silver stain showing Helicobacter pylori organisms.

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Flashcard Set Title: "Goljan Rapid Review Images"


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.Spongiform encephalopathy in Creutzfeldt-Jakob disease showing classic bubbles and holes of the neuropil cell bodies

.Subendothelial immunocomplex deposits viewed with electron microscopy.

.Substantia nigra in a patient with Parkinson disease (A) and a normal individual (B)

.Tinea capitis due to Trichophyton tonsurans

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Flashcard Set Title: "Goljan Rapid Review Images"


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.Tinea corporis showing annular lesions with erythematous margins and clear centers

.subnuclear vacuoles (arrows) containing mucin push the nuclei of the endometrial cells toward the apex of the cell

Wernicke's encephalopathy showing hemorrhage and discoloration of mamillary bodies and the wall of the third ventricle

Wilson's disease showing cavitary necrosis of the putamen on both sides of the brain

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Flashcard Set Title: "Goljan Rapid Review Images"


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cytomegalovirus. The enlarged nuclei of many of the type I pneumocytes contain large inclusions

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