Neck Cancer Priscilla E. Bloom ARAMARK Dietetic Internship March 9, 2014 Abstract 52 year old Caucasian male Hypopahryngeal cancer Scheduled follow up showed uncontrolled diabetes and hyponatremia PEG tube placement Enteral Nutrition Disease Description Hypopharyngeal cancer occurs when malignant cancer cells are found on the tissues of the hypopharynx (1). The chances of developing hypopharyngeal cancer increase with the use of tobacco products, alcohol, an unbalanced diet, and having Plummer- Vinson syndrome, a disorder resulting in iron deficiency and web-like growth of membranes in the throat. Disease Description Cont. Stages of hypopharyngeal cancer: Stage 0 (Carinoma in Situ): abnormal cells are found in the lining of the hypopharynx, which can become cancerous or metastasize. Stage 1: cancer has formed in the hypopharynx and/or tumor size is two centimeters or smaller Stage 2: in this stage the tumor is either between two and four centimeter large and has not spread to the larynx or the tumor is found in more than area of the hypopharynx Stage 3: the tumor is larger than 4 centimeter and/or has metastasized to the larynx, esophagus, or nearby tissues of the hypopharynx Stage 4: Tumor has spread to cartilage around the thyroid, trachea, or nearby tissue. Timor has spread to one or more surrounding lymph nodes
Evidence Based Recommendations Evidence Analysis Library Use enteral nutrition (EN) to increase calorie and protein intake for outpatients with stage III or IV head and neck cancer undergoing intensive radiation treatment. Maintenance of nutritional status by EN during radiation therapy may improve tolerance of therapy to promote better outcomes.
Role of nutritional status in predicting quality of life outcomes in cancer- a systemic review of the epidemiological literature Twenty-six articles Six article specific to head and neck cancer All six articles concluded that better nutritional status positively correlated with quality of life, three of which showed a relationship between weight loss and swallowing function. Nutritional Surveillance and Weight Loss in Head and Neck Cancer Patients Two-year study evaluated if therapeutic approach, tumor site, tumor stage, BMI, gender, age, and civil status predicted body weight loss. Strongest predictor for weight loss was tumor stage Mean maximum weight loss for patients receiving EN and per oral feeding was 13% and 6% respectively Wait-and-See approach for PEG insertion Case Presentation A 52-year old Caucasian male who had a scheduled follow up with his physician. Upon arrival the patient presented with severe hyperglycemia with a blood sugar of 712. The patient was also found to be hyponatremic with sodium of 120 and a creatinine level of 2.4 with a GFR of 30. Patient was recently diagnosed with moderately differentiated squamous cell carcinoma of the hypopharynx and was receiving chemotherapy and radiation treatment.
Nutrition Care Process Assessment Client History Married and lives at home with his wife. The patient has a significant history of alcohol use and had a 30-50 pack year history of smoking, although, he stated that he quit six months ago. Family history shows that cancer is prevalent in this patients family with his father passing away from cancer at the age of 69 and his mother passing away at the age of 68 from liver and bone cancer. The patients medial history is remarkable for diabetes and compensated liver cirrhosis of unknown etiology and hypopharyngeal cancer. Food/Nutrition-Related History No specific diet or the use of supplements. Meds: Hydrochlorothiazide 12.5 mg one table by mouth daily, Lisonopril 20 mg one table by mouth daily, Metoprolol 100 mg one table by mouth, Compazine 10 mg one tablet by mouth every 6 hours as needed for nausea and vomiting. The patient was previously on Glipizide 5 mg by mouth twice a day, and was previously on Metformin 1000 mg one table by mouth twice a day. Nutrition-Focused Physical Findings Severe swallowing difficulties Dentures Poor p.o. intake Glucerna shakes 1800 kcal ADA diet Anthropometric Measurements 5 feet 9 inches and weighed 240# BMI of 35.4 (Obese)
Biochemical data, Medical Tests, and Procedures Nutrient Needs Estimated needs were based on patients current cancer condition, acute renal failure, and ideal body weight as actual body weight was greater than 125% IBW
Nutrient Needs cont. ARAMARK Nutrition Status Classfications Fair appetite (75% of needs for > 2 weeks) (2 points) BMI Range >35-39 (3 points) Albumin 3.0-3.4/Prealbumin 10-15 (2 points) Uncontrolled Diabetes (3 points)
Malnutrition Identification Six characteristics suggest malnutrition Insufficient energy intake Weight loss Loss of muscle mass Loss of subcutaneous fat Localized or generalized fluid accumulation that may sometimes mask weight loss Diminished functional status as measured by handgrip strength.
Nutrition Care Process Nutrition Diagnosis Swallowing difficulty (NC-1.1) RT mechanical causes AEB pt's comments, decreased estimated food intake, reports of drinking Ensure TID prior to admission.
Intervention 1. Carbohydrate-modified diet (ND-1.2): Continue with 1800 ADA diet, as tolerated by patient, to meet caloric needs and aid with glucose control. 2. Commercial beverage (ND-3.1.1): Will send Glucerna TID per pt's request. Glucerna TID will provide additional 660 kcal and 29.7 g protein 432mL water if consumed. 3. Enteral Nutrition (2.1): Continuous feeding of Glucerna 1.5 at 55 ml/hr with 30 ml flush every hour to provide 1584 kcals, 79.2 g PRO, and 1782 ml total fluid. *
Nutritional Goals 1. Patient will drink 100% supplement 2. Tolerance to enteral nutrition 3. Maintain skin integrity 4. Maintain current weight 5. Nutrition labs within normal limits
Monitoring and Evaluation Nutrition-Focused Physical Findings (PD): skin (1.1.8) Anthropometric Measurements: weight/weight change (1.1) Biochemical Data, Medical Tests and Procedures (BD): glucose (1.5), Food/Nutrition-Related History (FH): Enteral nutrition (1.3), nutritional supplements (1.2.1)
Conclusion Intern was allowed to sit in on the last follow up visit with the patient who reported a 14 pound weight gain and better swallowing function. The patient did report some taste alterations but overall the patient and his wife seemed to be very excited over the patients improvement. References 1.Hypopharyngeal Cancer Treatment (PDQ). National Cancer Institute at the National institutes of Health. http://www.cancer.gov/cancertopics/pdq/treatment/hypopharyngeal/HealthProfessional Updated on February 28, 2014. Accessed on March 2, 2014. 2. http://www.nlm.nih.gov/medlineplus/druginfo/meds/a682571.html#side-effects 3. http://www.nlm.nih.gov/medlineplus/druginfo/meds/a692051.html#side-effects 4. http://www.nlm.nih.gov/medlineplus/druginfo/meds/a682864.html#side-effects 5. http://www.nlm.nih.gov/medlineplus/druginfo/meds/a682116.html#side-effects 6. Ehrrson Y, Langius-Eklof A, Laurell G. Nutritional surveillance and weight loss in head and neck cancer patients. Support Care Cancer. 2012; 20: 757-756. 7. Lis C, Gupta D, Lammerfeld C, Markman M, Vashi M. Role of nutritional status in predicting quality of life outcomes in cancer- a systemic review of the epidemiological literature. Lis et al, Nutrition Journal. 2012; 11(27): 1-18. 8. Oncology (Onc) Head and Neck Cancer: Radiation and Use of Enteral Nutrition (EN). Evidence Analysis Library. http://andevidencelibrary.com/template.cfm?template=guide_summary&key=1754&highlight=Radiation% 20and%20Use%20of%20Enteral%20Nutrition&home=1. Accessed on March 6, 2014.