Source: Institute for Clinical Systems Improvement (ICSI). Community-acquired pneumonia in adults.

Bloomington (MN): Institute for Clinical Systems

Improvement (ICSI); 2006 May. 35 p.

Community-Acquired Pneumonia in Adults

Outpatient Management Algorithm

A = Annotation 13a
with
quinolone Azithromycin PLUS EITHER
high dose amoxicillin 1 g tid
11 OR high dose amox/clav 2 g bid
10
Previously healthy Recent antimicrobial yes
patients without therapy (last 3 months)?
comorbidities A
13b
no
Moxifloxacin OR levofloxacin
with non-
12 quinolone

Azithromycin OR
doxycycline
16a
with Azithromycin PLUS EITHER
quinolone high-dose amoxicillin 1 g tid
OR high-dose amox/clav 2 g bid
14 15 OR cefuroxime OR cefpodoxime
Patients with other OR cefprozil
Recent antimicrobial yes
comorbidities (COPD,
diabetes, CHF, renal therapy (last 3 months)?
failure, malignancies)
A
9 16b
no
Outpatient Management Moxifloxacin OR levofloxacin
with non-
• Treatment based on
17 quinolone
patient characteristics
• Patient education Azithromycin OR
• Follow-up moxifloxacin OR
A levofloxacin

18 19

Aspiration suspected Amox/clav OR clindamycin

20 21
Azithromycin PLUS
Nursing home patient amox/clav OR moxifloxacin
OR levofloxacin
A

22 23
Moxifloxacin OR levofloxacin
Recent influenza,
OR high-dose amox/clav 2 g bid
possible superinfection
OR cefuroxime OR cefpodoxime
A OR cefprozil

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