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Stage 1 Desired Results
(What the students will know, do, and understand)
Enduring Understandings :
Students will understand that
1. normal cell division is regulated by genes the
proto-oncogenes and tumor suppressor genes;
2. changes in these genes (mutations) result in
uncontrolled cell division which leads to the
development of cancer; and
3. environmental (mutagens) and genetic factors cause
the mutations of proto-oncogenes and tumor
suppressor genes.
Essential Questions :
1. How does cell division proceed at a normal rate?
2. What happens when cells lose control as they
divide?
3. How is the control of cell division lost?
Students will know
1. the complementary functions of proto-oncogenes
and tumor suppressor genes in cell division;
2. the series of events which lead to the development
of cancer, including the occurrence of mutations;
and
Students will be able to ...
1. identify factors/agents which cause the development
of cancer; and
2. design a comic strip which promotes awareness
about cancer, its causative factors and stages of
development.
UbD-based Lesson Plan
Subject : Science II (Biology) Level : Second Year
Unit : Cell Reproduction and Inheritance Time Frame : 1meeting
Lesson : Mutations and Cancer Designed by : Raquel E. Lizardo
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3. the difference between a benign tumor and a
malignant tumor.
Stage 2 Assessment Evidence
(Forms of assessment that will guide instruction)
Performance Task :
Comic strip design
Goal Design a comic strip aimed at increasing public
awareness about cancer (its causes and develop-
ment)
Role Graphic artist-writer
Audience key officials of the Dept. of Health (DOH),
including the Secretary
Situation You have been commissioned by the DOH to
design a comic strip which presents simple,
easy-to-understand, and interesting information
about cancer
Product Comic strip
Standards for evaluation Informative value (50%),
Visual and content appeal (30%),
Creativity (20%)
Other Evidence :
1. Observations
2. Question and answer
3. Written exercises
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Stage 3 Learning Plan
(Learning activities aligned with goals and assessment)
Introduction :
Students will share their prior knowledge and conceptions about cancer in a form of a thought balloon.
Interaction :
Through direct instruction, students will learn about (a) the series of events which lead to the development of cancer,
including mutations, and (b) the different factors/agents which cause cancer. They will then answer a set of questions in
a worksheet and analyze brief case studies to gauge their understanding of the concepts learned.
Integration :
Students will complete a concept map to link the knowledge and ideas learned from the lesson.
Values Integration :
Students will be asked to complete the following prompt :
I commit myself to the fight against cancer by
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Closure Statement :
Cancer results from the accumulation of damages to genes that control cell division, across time; these damages are
caused by environmental agents (mutagens) and/or genetic predisposition.
Materials : Charts, worksheets
References/Weblinks :
Purves, W.K., et al.2001. Life : The Science of Biology (6th Edition). W.H. Freeman and Company :
Massachusetts, USA.
http://learn.genetics.utah.edu/archive/proteinrole/
http://learn.genetics.utah.edu/archive/sloozeworm/
http://learn.genetics.utah.edu/archive/sloozeworm/scenario.html
http://learn.genetics.utah.edu/archive/sloozeworm/scenans.html
http://learn.genetics.utah.edu/archive/sloozeworm/mutationbg.html
http://info.cancerresearchuk.org/youthandschools/teachersresources/
ys_lesson_whatiscancer/
http://cancer.stanford.edu/information/geneticsAndCancer/genesCause.
Html.