Curriculum Vitae for Olusola “Sola” Soyemi PhD

2248 Whistler Drive,

Longmont CO 80504
Phone: 303-485-6316 (home); 774-287-2507 (cell)
Email: solasoy2000@yahoo.com

Citizenship: USA

Summary

Experienced Analytical Chemist/Industrial Scientist with a track record of achievement in

academic and multi-disciplinary research environments. Expertise in atmospheric and
process monitoring, optical spectroscopic sensor research for medical and industrial
applications, multi -dimensional data analysis, numerical analysis and scientific
programming/algorithm development.

Academic Experience

University of Massachusetts Medical School, MA 2003-2007

Research Instructor 2003-2006
Research Assistant Professor 2006-2007

DUTIES
Develop applications (relating to respiratory critical care, trauma or emergency medicine)
for a non-invasive spectroscopic tissue sensor. Subset of duties includes:
- Development of data analysis and visualization software.
- Spectroscopic analysis of complex (biological) samples;
- Data Mining & Numerical modeling - multivariate analysis of clinical
measurements (multivariate calibration and pattern
recognition);
- Publish research findings, present results at research conferences
Mentor medical students/research interns during lab rotations

ACCOMPLISHMENTS
• Key participant in the product development of a novel non-invasive clinical monitor, with
emphasis on implementing algorithms in real-time on the instrument.
• Developed novel spectroscopic methods for measuring important parameters in tissue
• Created significant Matlab libraries for use within spectroscopic instrument by non-expert
users.
• Developed novel methodology for calibration transfer across multiple units of
spectroscopic clinical instrument.
• Developed methodology for correcting the influence of skin pigmentation in in-vivo tissue
spectra.
• Summarized findings in technical reports, patent applications, oral presentations
and peer-reviewed journal articles.

University of South Carolina, SC 2000-2001

Postdoctoral Fellow

DUTIES
Concept development of multivariate optical computing technology (see www.ometric.com)

ACCOMPLISHMENTS
• Lead device evaluation and component fabrication efforts during the development and
demonstration of the first multivariate optical computing device. This novel approach to
predictive spectroscopy, which greatly simplifies traditional
1-D spectroscopy and spectral imaging, was featured on the cover of Analytical Chemistry in
March of 2001.
• Developed thin-film coating design software (using MATLAB) tailored towards the
fabrication of interference filters that are crucial to the implementation of multivariate
optical computing technology.
• Developed LabVIEW-based process control/optimization software for thin-film coating
fabrication system.
• Summarized findings in conference proceedings, peer-reviewed journal articles and oral
presentations.

Baylor University, TX. 1994-1999

Research/Teaching Assistant

DUTIES
Design of data acquisition and analysis systems in near infrared spectroscopy; analytical
method development. Teaching (Analytical Chemistry Laboratory, General Chemistry Tutor)

ACCOMPLISHMENTS
• Developed the use of Trichloromethane as a standard for wavelength calibration and
photometric accuracy in near infrared scanning spectrometers.
• Designed and built graphical user interface for a laboratory assembled near infrared
scanning spectrometer.
• Wrote a suite of software programs in LabVIEW for the multivariate analysis of spectral
data, which demonstrated the feasibility of data acquisition coupled with real-time
chemometric analysis of spectral data in a virtual instrument environment.
• Developed analytical method for the determination of pungency in chili peppers via near
infrared spectroscopy
• Summarized findings in peer-reviewed journal articles and oral presentations.

Industrial Experience

Zolo Technologies Inc. CO 2007-Present

Consultant 2009-Present
Spectroscopist/Scientific Programmer 2007-2009

DUTIES
Develop and deploy data analysis algorithms for a NIR tunable diode laser spectroscopic
sensor that is used for monitoring atmospheric gases in harsh environments such as coal-
fired power plants. Provide spectroscopic and software support for in-house high-
temperature laboratory and field installation team.

ACCOMPLISHMENTS
• Developed a robust algorithm for measuring temperature and water vapor in coal-
boilers that has since been successfully deployed in several US and international
power plants.
• Developed outlier detection method for monitoring real-time spectroscopic
measurements
• Developed LabVIEW-based software framework for characterizing analyzing
atmospheric emissions like H2O vapor, CO2, CO and O2 from gas-phase spectroscopic
measurements
• Determined critical physical constants for near-infrared water spectra at ultra-high
pressures (>5atm) that enable the real-time measurement of temperature in high
performance jet engines (in situ).

LifeScan Inc. (a Johnson and Johnson Company), CA 2001-2002

Senior Scientist

DUTIES
Medical device (glucose monitoring) research and development. Technology evaluation

ACCOMPLISHMENTS
• Used data mining tools to perform extensive analyses of tissue optical measurements from
several prototypes of a novel non-invasive glucose measurement device developed by a
third-party R&D company.
• Established and implemented framework for monitoring core research progress made by
the same R&D Company.

TEACHING EXPERIENCE

• Chemistry Instructor, Federal Polytechnic, Afikpo, Nigeria: 1993-1994

• General Chemistry (Lab and Tutoring sessions), Baylor University, Waco TX
• Analytical Chemistry (Lab and Tutoring sessions), Baylor University, Waco TX
• Physical Chemistry (Lab sessions), Baylor University, Waco, TX
• Guest Lecturer at the University of Connecticut, Storrs CT
Topic: “Assessment of Tissue Properties In Vivo Using Near Infrared Spectroscopy”
Graduate level class on Biosensors – BME 315 (One lecture/semester for 2
semesters)

SKILLS

Molecular Spectroscopy (UV-Visible, NIR, FT-NIR, FTIR, TDLAS), Physical/Analytical

Chemistry, Clinical Chemistry, multivariate data analysis, numerical modeling, process
monitoring, optical sensors, biomedical optics, wet chemistry, scientific programming
(MATLAB, LabVIEW), project management, written and verbal communication

EDUCATION

BS, Chemistry (GPA: 3.3/4.0), University of Ibadan, Nigeria, 1992

PhD, Chemistry (GPA: 3.8/4.0), Baylor University, TX, 2000
Dissertation: Design of Data Acquisition and Analysis Systems in Near Infrared
Spectroscopy: A Virtual Instrument Approach (2000).
Advisor: Kenneth W. Busch PhD

Postdoctoral Fellowship: University of South Carolina (2000-2001)

Advisor: Michael L. Myrick PhD

Professional Affiliations

Member, American Chemical Society (ACS) - Division of Analytical Chemistry 1999-Present

Member, Society for Applied Spectroscopy (SAS) – 1999-Present

Peer-Reviewed Publications

1. Noninvasively determined muscle oxygen saturation is an early indicator

of central hypovolemia in humans. Babs R. Soller, Ye Yang, Olusola O. Soyemi, Kathy L.
Ryan, Caroline A. Rickards, J. Matthias Walz, Stephen O. Heard, and Victor A. Convertino. J
Appl Physiol 104:475-481, 2008.

2. Oxygen saturation determined from deep muscle, not thenar tissue, is an early indicator
of central hypovolemia in humans. Babs R. Soller; Kathy L. Ryan; Caroline A. Rickards;
William H. Cooke; Ye Yang; Olusola O. Soyemi; Bruce A. Crookes; Stephen O. Heard; Victor
A. Convertino. Crit. Care. Med 36(1): 176-182, 2008.
3. Noninvasive measurement of venous blood pH during exercise using NIR reflectance
spectroscopy. Ye Yang, Olusola O. Soyemi, Michelle R. Landry, Babs R. Soller Appl
Spectrosc. 61(2): 223-229, 2007

4. Removal of analyte-Irrelevant variations from near-infrared tissue spectra. Ye Yang, Leah

Shoer, Olusola O. Soyemi, Michelle Landry, and Babs Soller. Appl Spectrosc. 60(9): 1070-
1077, 2006

5. Influence of the Fat Layer on the Near Infrared Spectra of Human Muscle: Quantitative
Analysis based on Two-Layered Monte-Carlo Simulations and Phantom Experiments. Ye
Yang, Olusola O. Soyemi, Michelle R. Landry, Babs R. Soller; Optics Express, 13(5): 1570-
1579, 2005.

6. Simultaneous Correction of the Influence of Skin Color and Fat on Tissue Spectroscopy by
use of a two-distance Fiber-Optic Probe and Orthogonalization Technique. Ye Yang, Michelle
R. Landry, Olusola O. Soyemi, Michael A. Shear, Dulce S. Anunciacion, and Babs R. Soller,
Optics Letters, 30(17): 2269-2271, 2005

7. Skin color correction for tissue spectroscopy: demonstration of a novel approach with
tissue-mimicking phantoms, Olusola O. Soyemi, Michelle R. Landry, Ye Yang, Patrick O. Idwasi, and
Babs R. Soller. Appl. Spectrosc 59(2): 237-244, 2005.

8. Online Reoptimization of Filter Designs for Multivariate Optical Elements. Frederick

Haibach, Ashley E. Greer, Maria V. Schiza, Olusola O. Soyemi, Michael L. Myrick., App.Opt
42(10): 1833 – 1838, 2003

9. Design of Angle-Tolerant Multivariate Optical Elements for Chemical Imaging. Olusola O.

Soyemi, Frederick Haibach, Paul J. Gemperline, Michael L. Myrick. App.Opt 41(10): 1936-
1940, 2002

10. A Single-Element All-Optical Approach to Chemometric Prediction. M.L. Myrick, O.O.

Soyemi, J. Karunamuni, D. Eastwood, H. Li, L. Zhang, A.E. Greer, and P. Gemperline. Vib.
Spectrosc. 28: 73-81, 2002.

11. Design and Testing of a Multivariate Optical Element: The First Demonstration of
Multivariate Optical Computing For Predictive Spectroscopy. Olusola O. Soyemi, DeLyle
Eastwood, Lixia Zhang, Hong Li, Jeevananda Karunamuni, Ronald Synowicki, Paul J.
Gemperline, Michael L. Myrick [COVER ARTICLE]. Anal. Chem, 73(6): 1069-1079, 2001.

12. Nonlinear optimization algorithm for multivariate optical element design. Olusola O.
Soyemi, Frederick H. Haibach, Paul J. Gemperline, Michael L. Myrick. Appl Spectrosc, 56(4):
477-487, 2001

13. Spectroelectrochemical study of the oxidative doping of polydialkylphenyleneethynylene

using iterative target transformation factor analysis. U. Evans, O. Soyemi, M. S. Doescher,
U. H. F. Bunz, L. Kloppenburg and M. L. Myrick. Analyst, 126(4): 508-512, 2001

14. Wavelength calibration of a dispersive near-infrared spectrometer using

trichloromethane as a calibration standard. Kenneth W. Busch, Olusola Soyemi, Dennis
Rabbe, Karalyn Humphrey, Ben Dundee, and Marianna A. Busch. Appl Spectrosc., 54(9):
1321-1326, 2000

15. Determination of stray light levels in a dispersive near infrared spectrometer with
Trichloromethane. Kenneth W. Busch, Olusola Soyemi, Dennis Rabbe and Marianna Busch.
Appl Spectrosc,. 54(12), 1759-1766, 2000.

16. Multivariate Analysis of Near Infrared Spectra Using the G-Programming Language
Olusola O. Soyemi, Marianna Busch, Kenneth Busch. J. Chem.Inf. Comp.Sci, 40: 1093-
1100, 2000

CONFERENCE PROCEEDINGS & TRADE MAGAZINE ARTICLES

1. Design of a Modular, Dispersive Spectrometer for Fundamental Studies in Near Infrared

Spectroscopy. Olusola Soyemi, Dennis Rabbe, Ben Dundee, Kenneth Busch, and Marianna
Busch. Spectroscopy, 16(4): 24-33, 2001

2. A Simple Optical Computing Device for Chemical Analysis. Olusola. Soyemi, Paul.J.
Gemperline, Lixia Zhang, DeLyle. Eastwood, Hong. Li, Michael L. Myrick. Proc.SPIE. 4284,
17-28, 2001

3. Field applications of stand-off sensing using visible/NIR multivariate optical computing.

DeLyle Eastwood, Olusola O. Soyemi, Jeevanandra Karunamuni, Lixia Zhang, Hong Li, and
Michael L. Myrick. Proc.SPIE, 4199, 105-114, 2001.

4. Application of Multivariate Optical Computing to Near-Infrared Imaging. Michael L.

Myrick, Olusola O. Soyemi, Frederick G. Haibach, Lixia Zhang, Ashley E. Greer, Hong Li,
Ryan J. Priore, Maria V. Schiza, Josh R. Farr. Proc.SPIE, 4577, 148-157, 2002.

5. Application of Multivariate Optical Computing to Simple Near-Infrared Point

Measurements. Michael.L. Myrick, Olusola O. Soyemi, Maria V. Schiza, Jason R. Farr,
Frederick.G. Haibach, Ashley E. Greer, Hong Li and Ryan J. Priore. Proc.SPIE 4574, 208-
215, 2002.

6. Characterization of penetration depth as a function of optical fiber separation at various

absorption and scatter coefficients for a non-invasive metabolic sensor. Charles DeMilo,
Thomas Brukilacchio, Babs R. Soller, and Olusola Soyemi. Proc.SPIE. 5317, 128-138, 2004.

7. Standardization method for correcting spectral differences across multiple units of a

portable near infrared – based medical monitor. Olusola Soyemi, Michelle Landry, Ye Yang,
Babs Soller. Proc.SPIE. 5702, 6(17), 135-142, 2005.

8. In-Vivo, Noninvasive Measurement of Muscle pH during Exercise using Near Infrared

Spectroscopy. Olusola Soyemi, Michael Shear, Michelle Landry, Dulce Anunciacion, and Babs
Soller. Proc.SPIE, 6007, 6007ON1-6007ON8, 2005.

9. Multivariate Calibration with slowly responding reference measurements. Michael A.

Shear, Olusola O. Soyemi, Michelle Landry, and Babs Soller. Proc.SPIE, 60070O-1 –
60070O-2, 2005

10. Noninvasive Sensors in Critical Care Medicine: The use of Near Infrared Spectroscopy
for the detection of altered Microvascular Blood Flow in Severe Sepsis and Septic Shock. J.M
Walz, B. Soller, O. Soyemi, Y. Yang, M. Landry, and S.O. Heard. Proc.SPIE, 6380, 6380OU-
1- 6380OU-5, 2006.

PATENTS

1. Filter Design Algorithm for Multivariate Optical Computing. Michael L. Myrick, Olusola O.
Soyemi, Paul J. Gemperline. US Patent Number: 7,138,156 (2007)

2. Measuring Tissue Oxygenation. Olusola O. Soyemi, Babs R. Soller, Ye Yang. US Patent

Number: 7,532,919 (2009).
3. Systems and Methods for Correcting Optical Reflectance Measurements. Ye Yang, Babs R.
Soller, Olusola O. Soyemi, Michael Shear. US Patent Number: 7,616,303 (2009)

PRESENTATIONS

1. Multivariate Calibration with the G-Programming Language. Paper #578, 26th Annual
Conference of the Federation of Analytical Chemistry and Spectroscopy Societies,
Vancouver, B.C. October, 1999.

2. Novel Filter Design Method for Multivariate Optical Computing. Paper #SE06-08,
Southeast Regional Meeting on Optoelectronics, Photonics, and Imaging, Charlotte, NC.
September, 2000.

3. Interference Coating Design for Optical Computing Using Multivariate Nonlinear

Optimization. Paper #16., 27th Annual Conference of the Federation of Analytical Chemistry
and Spectroscopy Societies, Nashville, TN. September, 2000.

4. Recent Work in Multivariate Optical Computation. Annual meeting of the Southeastern

Association of Analytical Chemists, Greenville, NC. October, 2000.

5. Comparison of Two Novel Approaches to Designing Interference Coatings for Multivariate

Optical Computing. Paper #4205-45, SPIE International Symposium on Environmental and
Industrial Sensing: Intelligent Software and Analysis Systems, Boston, MA. November,
2000.

6. A Simple Optical Computing Device for Chemical Analysis. Paper #4284-05, SPIE
Symposium on Functional Integration of Opto-Electromechanical Devices and Systems:
Systems and Devices, San Jose, CA. January, 2001.

7. A Process Optimization Procedure for Multivariate Optical Element (MOE) Manufacture.

Paper #1582, Pittsburgh Conference and Exposition on Analytical Chemistry and Applied
Spectroscopy, New Orleans, LA. March, 2001.

8. Skin color correction in quantitative NIR tissue spectroscopy: Phantom studies. Critical
Care Conference, UMass Medical School, August, 2004

9. Removal of the effect of skin pigmentation in tissue spectra: demonstration with tissue
mimicking phantoms”, Paper #224, 31st Annual Conference of the Federation of Analytical
Chemistry and Spectroscopy Societies, Portland, OR. October 3-7, 2004.

10. Noninvasive monitor for continuous measurement of blood hematocrit, muscle pH and
PO2. Annual Conference of the American Society of Anesthesiologists (Scientific and
Educational Exhibit, #30), Las Vegas, NV, October, 2004

11. Medical Applications of Chemometrics. UMass/WPI Conference; November, 2004

12. Standardization method for correcting spectral differences across multiple units of a
portable near-infrared-based medical monitor. Paper #5702-23, 5th SPIE Symposium on
Optical Diagnostics and Sensing (SPIE Photonics West Conference), San Jose CA, January,
2005.

13. In-Vivo noninvasive measurement of muscle pH during exercise using near-infrared

spectroscopy (Invited Talk). Paper #609, 32nd Annual Conference of the Federation of
Analytical Chemistry and Spectroscopy Societies, Quebec City, QC, Canada. October, 2005.
14. In-Vivo noninvasive measurement of muscle pH during exercise using near-infrared
spectroscopy. Paper #6007-24, 3rd Annual SPIE Conference on Smart Medical and
Biomedical Sensor Technology, Boston, MA, October, 2005.

SERVICE

1. 2008-Present: Mentor, Greenhouse Scholars (a non-profit organization that provides

comprehensive personal and financial support to under-privileged and under-resourced
college students).

2. 2005-2007: Member, Program Committee, SPIE Conference on Smart Medical and

Biomedical Sensor Technology

3. 2002: Speaker Committee, Society of Applied Spectroscopy, San Francisco Bay Area
Section.

4. Manuscript Reviewer: Applied Spectroscopy

REFERENCES

1. Kenneth Busch PhD

Professor;
Department of Chemistry and Biochemistry
Baylor University; Waco, TX 76798
Phone: 254-710-6870 (office)
Email: Kenneth_Busch@baylor.edu

2. Michael Myrick PhD

Professor;
Department of Chemistry and Biochemistry
University of South Carolina; Columbia, SC 29208
Phone: 803-777-6018 (office); 803-429-1400 (cell)
Email: myrick@mail.chem.sc.edu

3. Babs Soller PhD

Professor;
Department of Anesthesiology
University of Massachusetts Medical School
Worcester MA 01655
Phone: 508-856-5904 (office)
Email: babs.soller@umassmed.edu

4. Andrew Sappey PhD

Chief Technology Officer;
Zolo Technologies Inc.,
Boulder, CO 80301
Phone: 303-604-5804 (office)
Email: asappey@zolotech.com