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AICAR is a peptide that increases energy production and prolongs cell life. It works by stimulating glucose uptake and protein kinases in skeletal muscle. Research on rats found AICAR improved endurance by converting muscle fibers. It may also treat ischemic injuries by inhibiting enzymes to enhance blood flow to the heart. When purchasing AICAR, researchers should check purity, quantity, and receive documentation for accurate study of its effects on animal test subjects under controlled conditions.
AICAR is a peptide that increases energy production and prolongs cell life. It works by stimulating glucose uptake and protein kinases in skeletal muscle. Research on rats found AICAR improved endurance by converting muscle fibers. It may also treat ischemic injuries by inhibiting enzymes to enhance blood flow to the heart. When purchasing AICAR, researchers should check purity, quantity, and receive documentation for accurate study of its effects on animal test subjects under controlled conditions.
AICAR is a peptide that increases energy production and prolongs cell life. It works by stimulating glucose uptake and protein kinases in skeletal muscle. Research on rats found AICAR improved endurance by converting muscle fibers. It may also treat ischemic injuries by inhibiting enzymes to enhance blood flow to the heart. When purchasing AICAR, researchers should check purity, quantity, and receive documentation for accurate study of its effects on animal test subjects under controlled conditions.
The peptide AICAR is a protein kinase agonist, meaning that it increases the usage of nutrient stores in order for the production of energy. It is tan in color, and is availale for purchase in po!der form. "o!ever, its purchase availaility is only for the e#pressed, e#clusive use of scientific study and research on animal test su$ects. The peptide is occasionally laeled under the names Acadesine or %&'. "o! AICAR (orks Before you purchase AICAR for scientific study on animal test su$ects, it is important that you are familiar !ith the intricacies on ho! the peptide functions !hen it is introduced. In essence, AICAR !orks y stimulating the glucose uptake and increasing the activity of p)* mitogen+activated protein kinases , and - in skeletal muscle tissue. Additionally, its reduction of reactive o#ygen compounds !ithin cells suppresses apoptosis. that is, the process of programmed cellular death that may occur in animal test su$ects. In other !ords, it increases the type of fuel responsile for the maintenance and regulation of skeletal muscle tissue !hile prolonging the life of cells. The functionality of AICAR !as pinpointed during e#tensive research conducted y the Salk Institute in /00*, !hen it conducted a attery of studies on laoratory rats. According to this particular research, it !as determined that the mice that !ere given AICAR e#hiited a significant improvement concerning endurance+type e#ercise. (hile the mechanics of this particular improvement !ere not isolated and specified, it !as theori1ed that it !as due to AICAR2s facility for converting fast+t!itch muscle fiers to slo!+t!itch muscle fiers. This conversion in turn allo!ed for a much higher rate of energy efficiency amongst the la rats. Additionally, the scientific tests noted that the conversion also allo!ed for a more efficient fat urning process amongst the animal test su$ects. AICAR2s Role in Treating Ischemic In$uries 3ther scientific study conducted on animal test su$ects has also determined that the peptide enters cardiac cells in order to inhiit adenosine kinase and adenosine deaminase. This process enhances the rate of nucleotide re+ synthesis elevates adenosine generation from adenosine monophosphate only during conditions of myocardial ischemia. Because of these properties, it is theori1ed that the peptide could e utili1ed for the treatment of and the safeguarding against various cardiac ischemic in$uries, !hich can either e construed as asymptomatic or rought upon y angina pectoris, !hich itself is primarily caused y arteriosclerosis and roken do!n into three different categories4 Stable angina 5 Chest discomfort that is rought aout y a measure of activity. This condition is typically aated !ithin several minutes of an activity eing stopped. Unstable angina 5 Also kno!n s crescendo angina, this form of acute coronary syndrome is marked y angina that changes or !orsens over a certain period of time. Microvascular angina 5 Also kno!n as Angina Syndrome 6, this condition is characteri1ed y angina+like chest pain, ut is theori1ed to e the result of spasm in the miniscule lood vessels of the heart as !ell as the arms and legs. It is theori1ed that AICAR2s functionality !ould inhiit the restriction of lood flo! to the heart muscle, !hich is a main condition of an ischemic in$ury. This in turn !ould enale the peptide to lo!er the risk of heart failure in animal test su$ects. Additionally, it !ould enale it to assist in treating an animal test su$ect in the aftermath of an ischemic in$ury, as the increase in lood flo! !ould allo! an animal test su$ects2 heart to e staili1ed. Purchasing AICAR If you determine that the mechanics of AICAR are eneficial for your scientific study on animal test su$ects, you should make sure you are follo!ing a couple of key steps in order to ma#imi1e the accuracy of your test results. The first step you should take is to check the purity of the peptide, as !orking !ith a diluted peptide may result in slight variances of scientific data that may ultimately cause issues over time, especially if your research is spread over several years. Secondly, you should make sure that you doule+check the 7uantity of AICAR you !ould e receiving, $ust to confirm that the amount you are receiving is sufficient for your animal test su$ect study. Additionally, you should ensure that you are receiving complete and accurate research materials to accompany your peptide2s purpose. Finally, you should al!ays ear in mind that AICAR is currently in the research phase, and any study on its functionality and effects on animal test su$ects should e contained to the confines of a strictly controlled environment like a laoratory or a medical research facility.