GHRP 2 Difficulties Impacting Research

Posted on March 12, 2014 by Maxim Peptide

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GHRP-2 refers to growth hormone releasing peptide. This is typically a comparale research element to GHRP !" a
similar synthetic #ersion of the natural peptide which is released in the ody of the test su$ect. These are high hgH
secretagogues which are designed to cause test su$ect%s ody" to increase their natural secretions of hgH
throughout their ody with an application of the chemical.
The asic reaction to GHRP 2 is created y stimulating the
pituitary gland while simultaneously encouraging the ody of
the test su$ects to secrete the necessary hormones. This will
cause an animal to produce an e&cessi#e amount of growth
hormone which can e used to control the way the ody
produces fat while increasing muscle mass in the tissue where
this peptide is applied.
GHRP 2 and GHRP 6 are interesting in the fact that they will
also increase an animal%s le#els of IG'-( which will affect the
functionality of the hypothalamus.
)ctions caused y )pplying
GHRP 2
*hen GHRP 2 is applied to an animal test su$ect" it is designed to mimic the effects of ghrelin.
*hen it reacts with natural tissues" GHRP 2 can increase the consumption of food" which is similar to the reactions
of ghrelin. GHRP 2 will also stimulate the secretion of growth hormone.
GHRP 2 will fre+uently e infused prior to its application to increase the growth hormone le#els in an animal to that
these le#els will grow in e&cess. This will in turn promote the secretion of cell c),P which will differ from the trends
commonly seen from GR'.
-upplements that are applied in research settings to e&pose animals to GHRP2 will typically ha#e anti-inflammatory
properties" ut the specific results that this will ha#e appears to #ary amongst test su$ects" e#en if the su$ects are
of the same species. There is an increased #ariance when comparing these effects across studies that ha#e used
different types of mammals to gain these results.
,uch of what appears to impact the results of applying GHRP 2 to an animal test su$ect is how the uni+ue pituitary
somatorophs respond. )nimals appear to ha#e a uni+ue set of receptor sutypes of GHRP which will impact their
o#erall reactions to this chemical as well as the specific needs of the animal%s ody as it de#elops.
Difficulties Impacting Research
The main difficulty that is pre#enting researchers from ta.ing ad#antage of the properties of GHRP 2 is the fact that
the half-life for the product is #ery short" e#en when comparing it to similar peptides that ha#e een synthesi/ed for
li#e application.
The pea. of GHRP 2 appears aout (0 minutes after it is applies. )t the #ery latest you will see results in aout an
hour after in$ecting this peptide into an animal. In order to get the ideal results from administering this peptide it will
need to e applied daily" which is somewhat constricting.
These reactions are similar to GHRP ! which is synthesi/ed for the same purpose of stimulating the secretion of
growth hormones" to get a etter reaction of cortisol and PR1 while impro#ing the o#erall le#els of )2TH.
Ghrelin is somewhat different in its reactions ecause it tends to react to tissues as an antagonist which will
connect with growth hormone secretagogue receptors" which will simultaneously increase the ion influ& of calcium"
which will further impact the release of growth hormone.
Research into these reactions has egun to pro#e that these three peptides are #ery similar in their effecti#eness of
producing and controlling the le#els of GR' in animals. -pecifically" there appears to e a higher potency for GHRP
2 when it is compared to pre#ious le#els seen with GHRP ( or GHRP !.
GHRP 2 is typically compared to GHRP ! during research as these two synthesi/ed peptides ha#e a #ery similar
structure and appear to ha#e a similar functionality when they are applied to a li#e animal test su$ect.
There are sutle differences in the o#erall eha#ior of these chemicals" particularly if they are applied alongside
otherpeptides such as ipamorelin. The o#erall goal of research is to etter understand how an animal will react to a
synthesi/ed #ersion of these peptides #ersus the natural #ersions of these elements that are produced in the
pituitary or hypothalamus to determine the potential pharmaceutical applications these peptides may ha#e.
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