UNIVERSITY OF CEBU BANILAD

COLLEGE OF NURSING

DRUG STUDY

Patient________________________________________________________________ Age____ Hospital No._________ Room No.________
Impression/Diagnosis____________________________________________________ Attending Physican(s) _________________________
Allergy to_____________________________________________________________

Generic/Brand
Name &
Classification
(10%)
Dose, Strength,
& Formulation
(10%)
Indication/Mechanism of Drug
Action
(15%)
Adverse/Side
Effects
Drug
Interaction
(15%)
Nursing
Responsibilities
(20%)
Rationale
(10%)
Client Teaching
(20%)
Generic:

metoclopramide



Brand:

Reglan






Classification:

Antiemetic,
Dopaminergic
blocker, GI
stimulant
Ordered:




Timing:







Duration:





Other forms:

Tablets, oral
solution (syrup),
injection, orally
disintegrating
Indications:
Relief of symptoms of acute and
recurrent diabetic gastroparesis.
Short-term therapy (4-12 wk) for
adults with symptomatic
gastroesophageal reflux who fail to
respond to conventional therapy.
Parenteral: Prevention of nausea
and vomiting associated with
emetogenic cancer chemotherapy.
Prophylaxis of postoperative
nausea and vomiting when
nasogastric suction is undesirable.
Single-dose parenteral use:
Facilitation of small-bowel
intubation when tube does not pass
the pylorus with conventional
maneuvers. Single-dose parenteral
use: Stimulation of gastric
emptying and intestinal transit of
barium when delayed emptying
interferes with radiologic
examination of the stomach or
small intestine.

CNS:
restlessness,
drowsiness,
fatigue, lassitude,
insomnia,
extrapyramidal
reactions,
parkinsonism-
like reactions,
akathisia,
dystonia,
myoclonus,
dizziness, anxiety

CV: transient
hypertension

GI: nausea,
diarrhea

Interactions
Drug-drug:
-Decreased
absorption of
digoxin from the
Before:
-Assess patient if
allergic to
metoclopramide.

During:
-Monitor BP carefully
with IV administration.

After:
-Monitor for
extrapyramidal reactions
and consult physician if
they occur.

-Keep diphenhydramine
injection readily
available in case
extrapyramidal reactions
occur (50 mg IM).

-For safety purposes.




-To ensure patients BP
is stable.


-These medications can
cause serious and
potentially permanent
side effects.

-This medication reverses
the symptoms of
extrapyramidal side
effects


-Take this drug exactly
as prescribed.

-Do not use alcohol,
sleep remedies, or
sedatives; serious
sedation could occur.

-You may experience
these side effects:
Drowsiness, dizziness
(do not drive or perform
other tasks that require
alertness); restlessness,
anxiety, depression,
headache, insomnia
(reversible); nausea,
diarrhea.

-Report involuntary
movement of the face,
eyes, or limbs, severe
depression, severe
diarrhea.
tablets Mechanism of Action:
Stimulates motility of upper GI
tract without stimulating gastric,
biliary, or pancreatic secretions;
appears to sensitize tissues to
action of acetylcholine; relaxes
pyloric sphincter, which, when
combined with effects on motility,
accelerates gastric emptying and
intestinal transit; little effect on
gallbladder or colon motility;
increases lower esophageal
sphincter pressure; has sedative
properties; induces release of
prolactin.
(Karch, 2012)

stomach
-Increased toxix
and
immunosuppressi
ve effects of
cyclosporine
-Increased
neuromuscular
blocking effects
with
succinylcholine

Ms. Jean P. Bernal, RN, MAN Heather Hao
Printed Name & Signature Printed Name & Signature
Clinical Instructor Student