VINAYAKA MISSIONS UNIVERSITY

Vinayaka Missions Kirupananda Variyar Engineering College

SALEM 636 308

Project Title

A BIOSENSOR BASED ON SILVER ENHANCED
SELF-ASSEMBLED RADIO FREQUENCY ANTENNA

Project Title

SAJITH S NAIR

08148549846 sajithsnair3@gmail.com

R. SWALAKSHM

09597057389 suvabme@gmail.com

S.SEEMA

08015141796 seemasushmi@gmail.com

ABDUL NASIR

08675010927 nasirkayyar@rocketmail.com
Department

Biomedical Engineering

Guide Name

Prof. S. MATHANKUMAR


Stream


Electronics & Communication Engineering


Title : A BIOSENSOR BASED ON SILVER ENHANCED SELF-
ASSEMBLED RADIO FREQUENCY ANTENNA
INTRODUCTION
This proposed project will introduce a new era in medical field. This will help to identify the
disease and will provide a fixed dosage for the disease. Let us consider todays treatment
method, if patients of high fever or low fever approach a doctor he will prescribe the
medicine with same dosage. While adopting this method we will be able to give the exact
dosage for the disease and eliminate. The pathogens by using Self assembled silver enhanced
antenna. The importance of modified biosensor is notified here.
We show that a silver-enhancement technique can be used to self-assemble a radio-frequency
(RF) antenna, which then can be used for designing a radio-frequency identification (RFID)-
based biosensor. Using the proposed biosensor, the concentration of target analytes or
pathogens can be remotely interrogated in a concealed, packaged, or in a bio-hazardous
environment, where direct measurement is considered to be impractical. In the presence of
the target analytes or pathogens, a silver-enhancement process self-assembles a chain of
micromonopole antennas. As the size of the silver-enhanced particles grow, the chain of
microantenna segments bridges together to complete a dipole structure that reflects impinging
RF signals at a desired frequency. We validate the proof-of-concept for IgG detection and
demonstrate that different concentrations of rabbit IgG (ranging from 20 to 60 ng in this
letter) can be detected based on the strength of the reflected RF signal received at a 915-MHz
COTS RFID reader
OBJECTIVE
Targeting principle as its name suggests can target a disease causing cell and can remove it
from its roots. Latest innovations are proceeding in the field of targeting a specific cancer cell
without even damaging the adjacent cells as in case of chemotherapy.
BIO-SENSOR BASED ON SILVER ENHANCED RFID ANTENNA.
Using the RFID antenna , Radio Frequency Identification, receives and transmit signals from
biosensors can be obtained.The pathogens or analytic can be easily detected and can be used
in any environment.
In the presence of pathogens the silver enhancement processes a self assembled chain of
micro monopole antenna..The chain of micro monopole antenna segment forms a dipole
structure to produce the signal of desired frequency.
DI AGRAMATI C REPRESENTATI ON


WORKING PRINCIPLE
An antenna on insulated structure which will act as a grafting substance, in which a self
assembled micro antenna is situated. To gain this a gap is created and is filled with
Nitrocellulose (NC) membrane. A complete sandwich structure is formed when a conjugate is
added due to the hybridization of antigen-antibody.
The unbound elements like aigG-AGNP are washed because of the capillary force of
nitrocellulose membrane. The gap on antenna is electrically insulated due to the size of gold-
nano particle. The sandwich structure is exposed to proprietary silver enhancement solution
during silver enhancement process which contains AgNO
3
and hydroquinone. In the presence
of gold nano particles, which act as a catalyst, the silver ion is reduced into metallic silver.
Silver ion reduces more as the time increases and bridges the antenna gap. This result in the
stronger or equal interrogation signal distance for RFID tag.
BEFORE AND AFTER OF SILVER ENHANCEMENT
On the surface of the NC membrane only sandwich structure is functionalised before
silver enhancement. Due to the porous nitrocellulose, the texture of nitrocellulose
membrane is varied.
A micro antenna is formed due the deposition of metallic silver on gold nano
particles, and is obtained after silver enhancement.
CONCLUSION
By using biosensor based on silver enhanced self assembled radio frequency antenna we can
detect pathogens in real life environment.

REFERENCES

Metal-enhanced Electrochemical Biosensor and Nanoremediation - By Isaac
Odhiambo K'Owino

Mingquan Yuan , Sensor Based on Silver-Enhanced Assembled Radio Frequency
Antennas Dept. of Electr. & Comput. Eng., Michigan State Univ., East Lansing, MI,
USA ; Alocilja, E.C. ; Chakrabartty, S. Sensors Journal, IEEE (Volume:14, Issue:
4 ), April 2014, PP. 941 942, 1530-437X.

Kenneth B. Crozier, Senior Member, IEEE, Wenqi Zhu, Dongxing Wang, Shiyun Lin,
Plasmonics for Surface Enhanced Raman Scattering: Nanoantennas for Single
Molecules JSTQE-INV-NB-04992-2013 1.


Nan Xiao, Chao Wang, Chenxu Yu. A Self-Referencing Detection of
Microorganisms Using Surface Enhanced Raman cattering Nanoprobes in a
Test-in-a-Tube Platform, Department of Agricultural and Biosystems Engineering,
Iowa State University, Ames, IA 50011, USA; Biosensors 2013, 3, 312-326;
doi:10.3390/bios3030312.