DRUG CLASS ACTION INDICATION CONTRAINDICATION ADVERSE EFFECT NSG INTERVENTION

PARACETAMOL
(Antipyretic,
Nonopiod)
Acts directly on heat-
regulating center to
cause vasodilation
and sweating
Temporary reduction
of fever, back and
muscle aches
Allergy to
acetaminophen u/c
impaired hepatic,
chronic alcoholism
Headache, Dyspnea,
hepatic toxicity and
failure
Shake well before use
give drug with food
DC if hypersensitivity
occurs
Ceftriazone
3
rd
generation
cephalosporin
Inhibits synthesis of
bacterial cellwall
causing celldeath.
Intra-abdominal
infections caused by
E.coli, Klebsiella
pneumoniae
Contraindicated with
allergy to
cephalosporins or
penicillins. Use
cautiously with renal
failure, lactation,
pregnancy
Pain
Induration
Phlebitis
Rash
Diarrhea
Thrombocytosis
Leucopenia
Glossitis
Respiratory
superinfections
Assess patient
forsigns
andsymptoms of
infection
beforeandduring
thetreatment
Aldactone
Spironolactone
Potassium-sparing
diuretic
Completely blocks the
effects of aldosterone
in the renal tubule,
causing loss of
sodium and water
and retention of
potassium
Primary
hyperaldosteronism,
adjunctive therapy in
the therapy in the
treatment of edema
associated with CHF,
nephritic syndrome,
hepatic cirrhosis,
treatment of
hypokalemia
Acute renal
insufficiency,
progressive renal
failure,
hyperkalemia, and
anuria. Clients
receiving potassium
supplements,
amiloride or
triamterene
Dizziness, headache,
drowsiness, rash,
cramping, diarrhea,
hyperkalemia,
hirsutism,
gynecomastia,
deepening of the
voice, irregular
menses
Instruct client not to
drive/operate
machinery until drug
effects are realized
may cause
drowsiness or uneasy
gait. Report if deep,
rapid respirations,
headaches or mental
slowing occurs; may
indicate
hyperchloremic
metabolic acidosis.



Rosuvastatin calcium
Crestor
A fungal metabolite
that inhibits the
enzyme (HGM-CoA)
that catalyzes the
first step in the
cholesterol synthesis
pathway, resulting in
a decrease in serum
cholesterol, serum
LDLs (associated with
increased risk of
coronary artery
disease) and either an
increase or no change
in serum HDLs
(associated with
decreased)
an adjunct to diet in
the treatment of
elevated total
cholesterol, mixed
dyslipidemia,
atherosclerosis
hypersensitivity,
impaired hepatic
function, alcoholism,
renal impairment,
advanced age,
hypothyroidism
Nausea, dyspepsia,
diarrhea,
constipation,
vomiting, rhinitis,
sinusitis, cough,
dyspnea, pneumonia

- Monitor patient
closely for signs of
muscle injury,
especially higher
doses
- Provide comfort
measures to deal
with headache,
muscle cramps, or
nausea
Vastarel MR
Trimetazidine
dihydrochloride

acts by directly
counteracting all the
major metabolic
disorders occurring
within the ischemic
cell.
Long treatment of
coronary
insufficiency, angina
pectoris.
Do not take Vastarel
MR if you are allergic
to any of the
constituents.
This drug is generally
not recommended
during breast feeding
Rare cases of GI
disorders.
use cautiously in
patients with heart
failure or
hypertension and in
elderly patients.
Clopidogrel
75 mg 1 tab POOD
Anti-platelet agents
Platelet aggregation
inhibitors
Reduction of
atherosclerotic
events (MI, stroke,
vascular death) in
patients at risk for
such events including
recent MI, acute
coronary syndrome
(unstable
angina/non-Q-wave
MI), stroke, or
Use Cautiously in:
Patients at risk for
bleeding (trauma,
surgery, or other
pathologic
conditions)History of
GI bleeding/ulcer
disease Severe
hepatic impairment
(CNS) Headache,
dizziness, and
myasthenia. (GI) N &
V and incontinence. (
CV) Hypotension.
(SKIN) Flushing pallor
sweating and
increased
perspiration
Assess patient for
symptoms of stroke,
peripheral vascular
disease, or MI
periodically during
therapy
peripheral vascular
disease.
Betamethasone
dipropionate
>Corticosteroid
(long acting)
>Glucocorticoid
>Hormone
Betamethasone is a
synthetic (man-made)
corticosteroid that is
used topically (on the
skin).
Ulcerative colitis,
acute exacerbations
of MS, and palliation
in some leukemias
and lymphomas
Trichinosis with
neurologic or
myocardial
involvement
Hypersensitivity
Systemic fungal or
acute infections
>Acne
>cracking and
stinging of the skin;
>dryness;
>excessive hair
growth;
>inflamed hair
follicles;
>itching; skin
irritation
Give daily dose
before 9 AM to
mimic normal peak
corticosteroid blood
levels.

Increase dosage
when patient is
subject to stress.