Precautions/Information to Know Cef- or ceph- Cephalosporin antibiotic cefazolin, cephalexin ceftin 5% cross sensitivity with penicillin Can cause GI distress -cillin penicillin antibiotic bicillin penicillin G Common allergy GI distress -mycin aminoglycoside or macrolide antibiotic gentamycin, tobramycin erythromycin Renal toxicity , ototoxicity with aminoglycosides -cycline tetracycline doxycycline minocycline Dental problems (enamel discoloration) for fetus if taken in pregnancy or before age 8 Interferes with oral contraceptives -gliptin DDP-4 inhibitor for treating diabetes vildagliptin (Galvus) sitagliptin (Januvia) watch for respiratory infections, headaches
-oxacin a fluoroquinolone antibiotic
Ciprofloxacin levofloxacin
photosensitivity reactions
-azoles indicates an antifungal Itraconazole fluconazole (Diflucan) clotrimazole ketoconazole miconazole (Lotrimin) very liver toxic, many drug-drug interactions -mab indicates a monoclonal antibody daclizumab injected, flu-like symptoms
-pine indicates a calcium channel blocker
amlodipine (exception verapamil doesnt end in pine) monitor BP, rhythm
-pril indicates an ACE inhibitor captopril
monitor cough -sartan indicates an angiotensin receptor blocker (ARB) valsartan not to be used during pregnancy -olol indicates a beta blocker propranolol acebutolol monitor cardiovascular effects, caution with diabetics
-ol indicates a beta agonist albuterol
rapid heart rate, sympathetic reaction
-osin indicates an alpha blocker doxazosin, prazosin first dose reaction; monitor for CHF -parin indicates an anticlotting agent heparin, dalteparin Injected; monitor for excessive bruising or bleeding -thiazide indicates a diuretic polythiazide, hydrochlorothiazide weight loss, fluid & electrolyte balance -ase indicates an enzyme, usually used with thrombolytics urokinase, streptokinase Monitor for bleeding -statin indicates an HMG CoA inhibitor lovastatin, pravastatin pregnancy category X, with diet and exercises, rhabdomyolysis -triptan indicates and antimigraine drug zolmitriptan
monitor BP, cardiac effects -enafil indicates an impotence drug sildenafil not with nitrates (can cause fatal hypotension) or alpha blockers; must be used with sexual stimulation -barbital indicates a barbiturate phenobarbital CNS depressant, stimulates liver enzymes to metabolize drugs -pam indicates a benzodiazepine diazepam (exception: chlordiazepoxide does not end in pam) liver and renal toxic -lukast indicates a leukotrience receptor antagonist zafirlukast Asthma maintenance drug Not for use in acute asthma attack -stim indicates a colony stimulating agent filgrastim injected; check bone marrow -prazole indicates an antisecretory agent omeprazole (Prilosec) esomeprazole (Nexium) (exception aripiprazole ends in prazole and is an antipsychotic agent not in this classification) Proton Pump Inhibitors (PPIs) are not for prolonged use: can cause hip fractures -setron indicates a centrally acting antiemetic ondansetron, granisetron injected, CNS depression
-azine indicates a phenothiazine promethazine CNS depressant
-sone indicates a corticosteroid cortisone, prednisone
timing of dose, risk of infection -esterone indicates a progestin progesterone annual pap smear -dronate indicates a calcium regulator etidronate
dosing details, monitor calcium -olone indicates an anabolic steroid androlone
liver and heart toxicity -asteride indicates an androgen inhibitor dutasteride Monitor urinary output -profen Indicates an NSAID ibuprofen Monitoring GI bleeding