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Curricula for II M.B.B.S.

Pathology
1. Goal
The goal of teaching pathology is to provide undergraduate students comprehensive
knowledge of the causes and mechanisms of disease, in order to enable them to
achieve complete understanding of the natural history and clinical manifestations of
the disease.
2. Educational objectives
(a) Knowledge
At the end of one and half years, the student shall be able to -
i. describe the structure and ultrastructure of a sick cell, the mechanisms of the cell
degradation, cell death and repair.
ii. Correlate structural and functional alterations in the sick cell.
iii. Explain the atho physiological processes which governs the maintenance of
homeostasis, mechanism of their disturbances and the morphological
and clinical manifestation associated with it.
iv. describe the mechanisms and patterns of tissue response to in!ury to appreciate the
athophysiology of disease processes and their clinical manifestations.
v. Correlate the gross and microscopic alterations of different organ systems in
common diseases to the extent needed to understand disease processes and their
clinical significance.
vi. "evelop an understanding of neoplastic change in the body in order to appreciate
need for early diagnosis and further management of neoplasia.
vii. #nderstand mechanisms of common haematological disorders and develop a
logical approach in their diagnosis and management.
(b) Skills
At the end of one and half years, the student shall be able to -
i. "escribe the rationale and principles of technical procedures of diagnostic
laboratory tests.
ii. $nterpret diagnostic laboratory tests and correlate with clinical and morphological
features of diseases.
iii. erform simple bedside tests on blood, urine and other biological fluid samples.
iv. "raw a rational scheme of investigations aimed at diagnosing and managing
common disorders.
v. %ecognise morbid anatomical and histopathological changes for the diagnosis of
common disorders.
(c) Integration
At the end of one and half years, the student shall be able to integrate the
causes and mechanisms of disease most prevalent in $ndia with their natural history
for the understanding of their clinical course and management.
. !otal duration of teaching & 'emesters ($$$, $) and )*
Mini"u" 1#
$or%ing days.
!otal nu"ber of teaching hours allotted to the disci&line '' hrs
"istribution of teaching hours
A* Theory (lectures + ,..-.-
tutorials* ,.. /0
Total ,..-/1
2* racticals ,..--.
C* %evision + Evaluation ($nternal* ,,&-
(. Syllabus
a. Learning methods
"istribution of teaching hours
)I*ISI+,S -. /EC!01ES B. !0!+1I-/S C.
P1-C!IC-/S
(- hr* (3 hrs* (3 -43 hrs*
-. 5eneral athology &/ .6 -3
3. 7aematology -/ .8 .6
&. 'ystemic athology 86 -& -0
8. Clinical athology .& .8 ./
/. Autopsy .- .- .3
------ -------- -------
T9TA: -.- 31x3 88x3./
------ ------- -------
b. & c. Sequential organization of course contents
The 2road area of study shall be;-
5eneral athology (including general neoplasia*
'ystemic athology (including systemic neoplasia*
7aematology
Clinical athology
-. GE,E1-/ P-!2+/+G3 4 5n6#.
-. "efinitions and causes of diseases;-
<ust know47 Able to recall common definitions in athology and causes of
cell in!ury.
3. <odes of cell in!ury;-
<ust know47 Able to appreciate mechanisms of cell in!ury + relate them to
the morphological changes.
&. =ecrosis + gangrene;-
<ust know47 Able to recogni>e types of necrosis and gangrene at gross and
microscopic levels.
"esirable to know47 Apoptosis and its relevance.
8. $ntracellular accumulations and alterations;-
<ust know47 Able to list the types of intracellular accumulations + alterations
in reversible cell in!ury along with alterations in cell organelles and
cytoskeleton.
/. Cellular Adaptations4 5rowth disturbances;-
<ust know47 "efine the various growth disturbances and appreciate the
clinical significance of each.
?. Acute inflammation;-
<ust know47 "efine and describe changes occurring in acute inflammation
and integrate the changes with morphological patterns of in!ury.
6. Chemical mediators of $nflammation;-
<ust know47 "efinition, Classification, description of each type, role of acute
chronic inflammation.
0. Chronic inflammation (including granulomatous*;-
<ust know47 differentiate it from acute inflammation, describe aetiology,
patterns and systemic effects of granulomas.
1. %egeneration and repair (general*;-
<ust know47 "efine + describe regeneration and repair and understand the
mechanisms and list factors modifying repair.
-.. %epair in speciali>ed tissues;-
<ust know47 "escribe repair in fractures and parenchymal organs and list
modifying factors and complications.
--. 9edema;-
<ust know47 "efine oedema, classify and describe pathogenesis + correlate
morphology with clinical significance with emphasis on transudate and
exudate.
-3. 'hock;-
<ust know47 "efine, classify and understand pathogenesis, recogni>e the of
mediators and stages of shock.
-&. Thrombosis;-
<ust know47 "escribe etio-pathogenesis, fate, morphology and effects of
thrombosis.
-8. Embolism and $nfarction;-
<ust know47 Enumerate types of embolism and infarction, recogni>e
morphological changes and correlate clinical significance.
-/. 7yperaemia and 7aemorrhage;-
<ust know47 "efinitions, morphology of acute and chronic congestions,
clinical significance of haemorrhage.
-?. "isturbances of pigment metabolism;-
<ust know47 'tate the type of pigment disturbances and describe the changes
associated with common disturbances like lipofuscin, melanin, 7emosiderin
and 2ilirubin.
-6. "isturbances of <ineral metabolism;-
<ust know47 "escribe the types and morphological changes of calcification.
"esirable to know47 "isturbances of other minerals like >inc etc.
-0. 5enetic disorders;-
<ust know47 =ormal karyotype, classification of genetic disorders, types of
genetic change, "own@s syndrome, Alinefelter@s syndrome, Turner@s syndrome
"esirable to know47 :ysosomal storage disorders, glycogen storage diseases,
methods of disease diagnosis.
-1. 7ypersensitivity reactions;-
<ust know47 Classify, differentiate between different types of
7ypersensitivity reactions.
"esirable to know47 2e conversant with transplant re!ections.
3.. Autoimmune diseases;-
<ust know47 #nderstand mechanisms of autoimmunity and diagnose common
autoimmune diseasesB overview of ':E.
3-. Amyloidosis;-
<ust know47 "efinition, physical characters, chemical characters,
classification, pathogenesis morphology, clinical correlation and lab diagnosis.
33. A$"';-
<ust know47 #nderstand the natural history of the disease and recommend
relevant investigations in the management.
3&. Typhoid fever;-
<ust know47 Correlate athogenesis with morphology and clinical features of
the disease.
38. 'yphilis;-
<ust know47 Classify and describe lesions in various stages of syphilis
3/,3?,36 (& lectures* Tuberculosis;-
<ust know47 Appreciate the importance of tuberculosis in the present day
Context, its athogenesis + basic histopathology. :ist and describe the
various pulmonary lesions of tuberculosis. "escribe changes in various
organs in T2 and understand their functional correlation, seCuelae, lab
diagnosis and T2 in A$"'.
30. :eprosy;-
<ust know47 Classify, differentiate between different types of leprosy and
describe the diagnostic histologic features and seCuelae.
31. Dungal diseases;-
"esirable to know47 Classification and be conversant with relevance of
fungal diseases in the world with emphasis on opportunistic fungal infections.
&.. <alaria;-
<ust know47 $dentify, morphological features in vivax and falciparum malaria
and recommend lab investigations in the management.
&- + &3. =eoplasia - =omenclature and classification;-
<ust know47 "efine important terms, classify and differentiate benign from
malignant neoplasms.
"esirable to know4 recancerous conditions
&&. =eoplasia - Carcinogenesis;-
<ust know47 #nderstand carcinogenesis and analyse the mechanism of
genetic changes in carcinogenesis.
&8. =eoplasia - 2iology and :ab diagnosis;-
<ust know47 #nderstand the tumour host interactions in neoplasia and
recommend the diagnostic workup for detection of cancer.
&/. =eoplasia - 'pread, grading and staging;-
<ust know47 2iology of tumour growth, metastases, types, mechanisms,
clinical correlations, grading of cancer and staging of cancer.
B. 2-EM-!+/+G3 4 5n61#.
-. $ntroduction to haematology and hemopoiesis;-
<ust know47 #nderstand the importance of haematology in clinical practice
and enumerate the stages of hemopoiesis.
3. Anaemias (general*;-
<ust know47 "efinition, classify anaemia by various methods, clinical
features and lab approach to anaemias.
&. $ron deficiency anaemia;-
<ust know47 "efinition, causes, haematological features, morbid anatomical
features, laboratory diagnosis and differential diagnosis.
8. <egaloblastic anaemia;-
<ust know47 "efinition, causes, haematological features, morbid anatomical
features, laboratory diagnosis and differential diagnosis.
/. 7aemolytic anaemia;-
<ust know47 "efinition, classification, athogenesis and haematological
features.
?. 7aemoglobinopathies;-
<ust know47 "efinition, classification, :ab diagnosis of Thalassaemia and
'ickle cell anaemia.
6+0. 7aemorrhagic disorders;-
<ust know47 Classify haemorrhagic disorders, describe clinical distinction
between urpuras and Coagulation disorders and laboratory screening tests for
haemorrhagic disorders. =ormal coagulation and fibrinolytic mechanism.
"escribe etio-pathogenesis, clinical significance and lab diagnosis of
haemophilia and "$C."escribe etio-pathogenesis, morphological features
(haematological and morbid anatomical* clinical significance and lab
diagnosis of $T.
1. :eukocytic disorders;-
<ust know47 :eukocytosis, :eukopenia and :eukemoid reactions.
-.. Acute :eukaemias;-
<ust know47 Classify and differentiate different types of acute :eukaemias.
--. Chronic :eukaemias;-
<ust know47 "efinition, general features, classification, aetiology,
haematological change, morbid anatomy, clinical course and lab.
investigations.
-3. araproteinemia;-
"esirable to know47 #nderstand the relevance of paraproteinemiaEs and
integrate the various diagnostic modalities with the diagnosis.
-&. Aplastic Anaemias;-
"esirable to know47 Aplastic anaemias and Agranulocytosis.
-8. 2lood groups;-
<ust know47 Appreciate the relevance of blood groups in haematology and
transfusion medicine. Erythroblastosis foetalis
-/. 2lood Transfusion;-
<ust know47 $ndications, selection of blood donors, autologous transfusions,
complications of blood transfusions, investigation of suspected transfusion
reactions.
C. S3S!EMIC P-!2+/+G3 4 5n6(8.
-. Atherosclerosis;-
<ust know47 "efinition, etiopathogenesis, gross and microscopic description,
complications and clinical correlation.
3. 7ypertension;-
<ust know47 %elate the mechanisms of the disease to the clinical course and
seCuelae.
&. 9ther diseases of blood vessels;-
<ust know47 "evelop an index of suspicion for vasculitides and aneurysms.
8. $schaemic heart disease;-
<ust know47 $ncidence, risk factors, athogenesis, morphological changes,
clinical course, complications and investigations.
/. Congenital heart disease;-
"esirable to know47 Correlate the anatomical malformations of disorders to
the clinical conseCuences of the disease.
?. %heumatic heart disease;-
<ust know47 $ncidence, etiopathogenesis, morbid anatomy, histopathology,
lesions in the organs, clinical course and seCuelae.
6. Endocardial and pericardial diseases;-
<ust know47 $nfective endocarditis - athogenesis, morphology, differential
diagnosis of cardiac vegetations, aetiology and basic morphology of different
forms of pericarditis.
0. Cardiomyopathies;-
"esirable to know47 %ecogni>e the disorders as part of differential diagnosis
in primary myocardial diseases.
1. neumonias;-
<ust know47 Aetiology, classification, gross, histopathological description in
different forms and complications.
-.. :ung Abscess and 2ronchiectasis;-
<ust know47 Etiopathogenesis, morphological appearances and complications.
--. Chronic 2ronchitis and Emphysema;-
<ust know47 athogenesis, types of emphysema, definition of chronic
bronchitis, morbid anatomy and cardiac seCuelae.
-3. 9ccupational lung diseases;-
<ust know47 Types, etiopathogenesis, gross anatomical differences between
different forms and seCuelae.
-&. Tumours of lung and pleura;-
<ust know47 Classification, aetiology, gross appearances, histological
description of important forms, natural history, pattern of spread, ara
neoplastic syndromes and secondary athology.
-8. :esions of oral cavity and salivary glands;-
<ust know47 "ifferential diagnosis of swelling of salivary glands, oral cancer
- etiopathogenesis, gross and histopathological descriptions.
-/. 5astritis and eptic #lcer;-
<ust know47 "efinition of peptic ulcer, etiological factors, gross and
microscopic appearances and seCuelae.
"esirable to know47 9verview of aetiology and types of gastritis.
-?. #lcers of $ntestines;-
<ust know47 Etiological classifications, <orphological appearances of
typhoid, tubercular, amoebic ulcers and bacillary dysentery. "ifferential
diagnosis of different forms of ulcers.
-6. $diopathic $nflammatory 2owel disease;-
<ust know47 Enumerate similarities and differences between the two
component disorders vi>., Crohn@s disease and ulcerative colitis.
-0. Tumours of upper 5$T;-
<ust know47 Etiopathogenesis, morphological features of carcinoma
oesophagus, classification and morbid anatomy and histopathology of gastric
carcinomas.
"esirable to know47 9verview of carcinoid tumours of 5$T.
-1. Tumours of lower 5$T;-
<ust know47 athology of carcinoma colon.
"esirable to know47 $ntestinal polyps + 5$ stromal tumours.
3.. )iral 7epatitis;-
<ust know47 Aetiology, clinical source and en>ymology, salient histological
features and seCuelae.
3-. Alcoholic liver disease;-
<ust know47 athogenesis, morphological manifestations and correlation with
clinical features.
33. Cirrhosis;-
<ust know47 Etiopathogenesis, classification, important histological features
and differential diagnosis.
3&. Tumours of liver, ancreas and gall bladder;-
<ust know47 athology of 7epatocellular carcinoma.
"esirable to know47 athology of tumours of ancreas and gall bladder.
38. "iabetes mellitus;-
<ust know47 Classification, pathogenesis of system involvement, seCuelae and
complications.
3/. Acute nephritis and rapidly progressive 5=;-
<ust know47 #nderstand and integrate clinical and pathologic features of
these syndromes.
3?. =ephrotic syndrome;-
<ust know47 $ntegrate clinical and pathological features of this disorder.
36. %enal failure;-
<ust know47 "efinitions, criteria, aetiology, systemic manifestations and
investigations.
30. yelonephritis and interstitial =ephritis;-
<ust know47 Aetiology, athogenesis of yelonephritis acute and chronic
morphological features and clinical correlation.
31. Tumours of kidney and elvis;-
<ust know47 Classification, <orphological features, clinical course including
ara neoplastic syndromes of common tumours.
&.. Tumours of testis and rostate;-
<ust know47 Classification, salient morphological features of most common
tumours and clinical course.
&-. Tumours of Cervix and #terus;-
<ust know47 Etiopathogenesis, salient morphological features, dysplasia and
role of cytological screening.
&3. Tumours of 9vary and trophoblastic tissue;-
"esirable to know47 Classification and morphological description of important
types.
&&. =on-neoplastic and =eoplastic lesions of the breast;-
<ust know47 Classification, morphological features and grading of carcinoma
breast and differential diagnosis of breast swellings.
&8. =on-neoplastic lesions of lymph nodes and 'pleen;-
<ust know47 Aetiology, differential diagnosis, morphological features of
common causes of lymphadenopathy, common causes and appearances of
splenomegaly.
&/. 7odgkin@s :ymphoma;-
<ust know47 "efinition, classification, salient diagnostic features and clinical
course.
&?. =on-7odgkin@s :ymphoma;-
<ust know47 "efinition, classification, salient diagnostic features and clinical
Correlation.
"esirable to know47 Extra nodal lymphomas.
&6. Tumours of skin - =on-pigmented;-
<ust know47 Classification, morphological features of most common types
and natural history.
&0. Tumours of skin - igmented;-
<ust know47 Classification, morphological features of common naevi, natural
history of malignant melanoma.
&1 +8.. 'oft tissue tumours ;-
<ust know47 Classification, morphological features of lipomatous, fibrous and
blood vessel tumours. <orphological features of neural, muscle and fibro
histiocytic tumours.
8-. =on-neoplastic lesions of bone and !oints;-
<ust know47 Etiopathogenesis and morphological changes of common
arthritis and osteomyelitis.
83 + 8&. Tumours of bone, cartilage and !oints;-
<ust know47 Classification, radiological and pathological features of
important bone tumours (9steosarcoma, 9steochondroma, 5CT and Ewing@s
sarcoma*.
88. $nflammatory and neoplastic conditions of C=';-
<ust know47 <orphological features and differential diagnosis of meningitis.
"esirable to know47 Classification, morphological features of important C='
tumours, clinical course and seCuelae (<eningioma and 5liomas*.
8/. :esions of Thyroid;-
<ust know47 "ifferential diagnosis of thyroid nodule.
8?. <yopathies;-
"esirable to know47 "ifferential diagnosis of common muscle disorders.
). C/I,IC-/ P-!2+/+G3 4 5n6.
-. "ifferential diagnosis of Faundice;-
<ust know47 The differential diagnosis and laboratory investigations in
!aundice
3. %enal function tests;-
<ust know47 :aboratory approach to a case of renal dysfunction
-. "iabetes mellitus;-
<ust know;- :aboratory diagnosis of "iabetes mellitus
E. -0!+PS3 4 5n61.
<ust know;- $ndications and techniCues of medical autopsies
Tutorials
GE,E1-/ P-!2+/+G34
-. Cell in!ury and cell death
3. Cellular accumulations
&. $nflammation and repair
8. Circulatory disturbances
/. $mmunological disorders
?. $nfections
6. =eoplasia
2-EM-!+/+G34
-. Anaemias
3. :eukaemias
&. $nterpretation of haematological case charts and identification of instruments
8. 7aemorrhagic disorders
S3S!EMIC P-!2+/+G34
-. Atherosclerosis and $7"
3. %heumatic heart disease
&. neumonias
8. Tumours of lung
/. 9ral cancer
?. eptic #lcer
6. Cirrhosis
0. 5lomerulonephritis
1. Carcinoma 2reast
-.. Carcinoma Cervix
--. 2one Tumours
-3. <useum specimens
-&. <useum specimens
C/I,IC-/ P-!2+/+G34
-. 5lucose Tolerance Test
3. %enal Dunction Tests
&. "ifferential "iagnosis of <eningitis
8. $dentification of needles and instruments used in clinical pathology
-0!+PS34
CPC of co""on diseases li%e 1. !uberculosis 2. Myocardial infarction .
Carcino"a9sarco"a (. 2y&ertension by students 52 or .
d. Termwise distribution
-st term; -. 5eneral athology 3. 5eneral =eoplasia &. 7aematology + Transfusion
<edicine
3nd term; -. 'ystemic athology 3. 'ystemic =eoplasia &. Clinical athology
&
rd
term; Tutorials + %evision.
e. !racticals" Total hours# number & contents
!otal hours 4 11' ,u"ber 4 ((
Contents 4
-. GE,E1-/ P-!2+/+G34 5n612.
-. <icroscopy and tissue processing
3. $dentify the common types of cells by light microscopy
&. $ntracellular accumulation
8. Acute inflammation
/. Chronic inflammation and %epair
?. Thrombosis, embolism, infarction and gangrene
6. 9edema and congestion
0. "isturbances of pigment metabolism
1. Tuberculosis
-.. :eprosy
--. Amyloidosis
-3. "isturbances of growth (Atrophy, hypertrophy, hyperplasia, metaplasia,
"ysplasia, hypoplasia*
B. 2-EM-!+/+G34 5n6:.
-. Collection of specimen, anticoagulants and common haematological tests (7b*
3. Common 7aematological Counts (T:C, ":C* + $nterpretation of E'%
&. 7aemopoiesis
8. $nvestigations in Anaemia
/. $nvestigations in :eukaemia
?. $nvestigations in haemorrhagic disorders
6. 2lood 2anking
C. S3S!EMIC P-!2+/+G34 5n61;.
-. "iseases of blood vessels (Atherosclerosis, syphilitic aortitis*
3. "iseases of 7eart ($7" + %7"*
&. neumonias
8. Tumours of lung
/. "iseases of kidney
?. 5ross and <icroscopic features of peptic ulcer and duodenal ulcer
6. 5ross and <icroscopic features of other intestinal ulcers
0. Tumours of 5$T
1. "iseases of :iver
-.. :ymphomas
--. "iseases of male and female genital system
-3 +-&. Tumours of breast
-8. Tumours of skin (igmented*
-/. Tumours of skin (non-pigmented*
-?. 'oft tissue tumours
-6. Tumours of bone
-0. "iseases of thyroid
). C/I,IC-/ P-!2+/+G34 5n6#.
-. #rine %E - Carryout a bedside routine urine examination and interpret the results.
3. regnancy test and 'emen Analysis - (ractical demonstration*.
&. Common cytological preparations (lecture demonstration*.
8. C'D examination.
/. 'erous effusion examination.
E. -0!+PS34 5n62.
- + 3* To study and describe five autopsy reports.
<or the batches joining in =une 2''1 and later
List of Slides and S$ecimens that should be shown during the !atholog% !ractical
&lasses
These are grouped under two headings; The students
-* must see (<*
3* desirable to see ("*
Please note that this $ill be a&&licable for the batch $hich $ill be joining
Pathology ter" in =une 9 =uly 2''1 and later.
)1->I,G S/I)ES4
'IST(!)T'(L(*+"
-. Aidney cloudy change (<*
3. Datty change liver (<*
&. #terus - leiomyoma with hyaline change (<*
8. Aidney - amyloid (<*
/. :ymph node - caseous necrosis (<*
?. Aidney - infarct (Coagulation necrosis* (<*
6. Acute ulcerative appendicitis (<*
0. yogenic meningitis (<*
1. :epromatous leprosy - skin (<*
-.. Tuberculoid leprosy - skin (<*
--. Actinomycosis (<*
-3. 5ranulation tissue (<*
-&. $leum - typhoid ulcer (<*
-8. Tuberculous lymphadenitis (<*
-/. Amoebic colitis (<*
-?. :ung - haemosiderin pigment or CC (<*
-6. :iver - CC (<*
-0. Artery - recent 4 organised thrombus (<*
-1. 7ashimoto@s thyroiditis ("*
3.. 'kin - papilloma (<*
3-. 'Cuamous cell carcinoma (<*
33. Adenocarcinoma - Colon (<*
3&. :ymph node - metastasis (<*
38. 'kin - capillary haemangioma (<*
3/. Cavernous haemangioma (<*
3?. 2enign cystic teratoma ("ermoid cyst* (<*
36. 'tomach - chronic peptic ulcer (<*
30. :iver - )iral hepatitis (<assive4 sub-massive necrosis* ("*
31. :iver- portal and biliary cirrhosis (<*
&.. :ung - lobar and broncho pneumonia (<*
&-. :ung - fibrocaseous tuberculosis (<*
&3. 7eart - rheumatic myocarditis ("*
&&. 7eart - healed infarct (<*
&8. Aorta - atherosclerosis (<*
&/. Aidney - crescentic glomerulonephritis (<*
&?. Aidney - chronic glomerulonephritis (<*
&6. Aidney - chronic pyelonephritis (<*
&0. Aidney - %CC ("*
&1. 2enign prostatic hyperplasia (<*
8.. Testis - seminoma (<*
8-. #terus - leiomyoma (<*
83. roducts of conception (<*
8&. 7odgkin@s lymphoma (<*
88. 2rain - tuberculous meningitis (<*
8/. 2rain - meningioma ("*
8?. 2one - osteogenic sarcoma (<*
86. 2one - chondroma (<*
80. 2one - osteoclastoma (<*
81. 'kin - melanoma and nevus (<*
/.. 2reast - fibroadenoma (<*
/-. 2reast - carcinoma (<*
/3. Thyroid - colloid goitre ("*
/&. Thyroid - papillary carcinoma ("*
/8. 'kin - basal cell carcinoma (<*
'),-)T(L(*+"
-. Acute blast cell leukaemia (<*
3. Chronic myeloid leukaemia (<*
&. Eosinophilia (<*
8. $ron deficiency anaemia (<*
/. 7aemolytic anaemia (<*
?. <acrocytic anaemia (<*
6. :eucocytosis (<*
0. )arious biochemical charts - :DT , 5TT , C'D, etc (<*
/IS! +< SPECIME,4
-. Cell in!ury and adaptation ("egeneration*
a* :iver - fatty change (<*
b* Aidney - cloudy change (<*
c* Aorta - atheroma (<*
d* Atheroma with calcification ("*
e* Aidney stones (<*
3. Amyloidosis
a* Aidney - amyloidosis (<*
b* 'pleen - amyloidosis (<*
&. =ecrosis and 5angrene
a* Aidney - infarct (<*
b* 'pleen - infarct (<*
c* $ntestine - gangrene (<*
d* Doot - gangrene (<*
e* :ymph node - caseation (<*
8. Acute inflammation
a*. :obar pneumonia (<*
b* Aidney - abscess ("*
c* :iver - abscess ("*
d* <ycetoma - foot ("*
e* Acute appendicitis (<*
f* urulent meningitis (<*
g* Dibrinous pericarditis (<*
/. Chronic inflammation
a* 'yphilitic aortitis ("*
?. %epair
a* 7eart - healed infarct (<*
6. 'pecific inflammation
a* $leum - typhoid (<*
b* Amoebic colitis (<*
c* Amoebic liver abscess (<*
0. Chronic specific granulomatous inflammation
a* $ntestine - T2 ulcer (<*
b* 2rain - T2 meningitis (<*
c* :ymph node - T2 (<*
d* :ung - miliary T2 (<*
e* Dibrocaseous T2 (<*
1. igment disorders
a*. :iver and spleen - russian blue reaction ("*
b*. :iver and spleen - malaria (<*
c*. 'kin - melanoma (any site* (<*
-.. "isorders of vascular flow and shock
a*. :iver - CC (<*
b*. :ung - CC (<*
--. Thrombosis embolism and infarction
a* Thrombus - artery 4 vein (<*
b* $nfarction - kidney 4 spleen 4 brain (<*
c* $ntestine gangrene (<*
-3. $mmunopathology
a* 7eart - %heumatic carditis (<*
b* Aidney - acute glomerulo nephritis (<*
c* Thyroid - 7ashimoto@s thyroiditis ("*
-&. 5rowth disorders
a* 7eart - :)7 (<*
b* Aidney - atrophy and compensatory hypertrophy (<*
c* Aidney - 7ydronephrosis (<*
-8. =eoplasm
a* apilloma skin (<*
b* Adenomatous polyp (<*
c* Dibroadenoma - breast (<*
d* 'Cuamous cell carcinoma - skin (<*
e* Adenocarcinoma - colon (<*
f* <etastasis - lung (<*
g* :eiomyoma - uterus (<*
h* 'oft tissue - lipoma (<*
!* 7aemangioma - any site 4 type (<*
k* <elanoma (<*
l* "ermoid cyst (<*
m* Teratoma (<*
-/. Alimentary 'ystem
a* 9esophagus carcinoma (<*
b* 'tomach - chronic peptic ulcer (<*
c* erforated peptic ulcer (<*
d* 'tomach - carcinoma (linitis plastica* (<*
e* $ntestine - T2 ulcer (<*
f* Colon - Amoebic colitis 4 bacillary colitis 4 carcinoma ulcerative 4
carcinoma
polypoidal growth (<*
-?. :iver
a* Acute diffuse necrosis ("*
b* Amoebic abscess (<*
c* <icronodular 4 macronodular 4 mixed cirrhosis (<*
d* 7epatoma (<*
e* <etastasis (<*
-6. %espiratory system
a* :ung - lobar 4 bronchopneumonia (<*
b* 2ronchogenic carcinoma (<*
c* :ung - abscess ("*
d* Dibrocaseous T2 (<*
-0. Cardiovascular 'ystem
a*. %heumatic endocarditis ("*
b* Dibrinous pericarditis (<*
c* <itral stenosis (<*
d* Aortic stenosis (<*
e* 2acterial endocarditis (<*
f* %ecent myocardial infarct ("*
g* 7ealed myocardial infarct (<*
h* Atheroma aorta (<*
!* Atheroma with complications (<*
-1. #rinary 'ystem
a* Dlea bitten kidney (<*
b* :arge white kidney (<*
c* 'hrunken granular kidney (<*
d* Acute pyelonephritis (<*
e* %CC ("*
f* Gilm@s tumour ("*
g* apillary carcinoma - #rinary bladder ("*
3.. <ale %eproductive 'ystem
a* 'CC - penis (<*
b* 'eminoma - testis (<*
c* Teratoma - testis (<*
d* 2enign prostatic hyperplasia (<*
3-. Demale %eproductive 'ystem
a* #terus - leiomyoma (<*
b* Carcinoma cervix ("*
c* 9vary - cyst adenocarcinoma ("*
d* 9vary - dermoid cyst ("*
3-. :ymphoreticular 'ystem
a* :ymph node - T2 :ymphadenitis (<*
b* :ymph node - lymphoma (<*
c* 'pleen - infarct (<*
33. Central =ervous 'ystem
a* 2rain - purulent meningitis (<*
b* 2rain - tuberculous meningitis (<*
c* Tuberculoma ("*
d* <eningioma ("*
e* 5lioma ("*
f* 7aemorrhage - C)A ("*
3&. 2one lesions
a* Chronic osteomyelitis ("*
b* 9steoclastoma (<*
c* 9steogenic sarcoma (<*
d* <ultiple myeloma ("*
38. 'kin lesions
a* 'Cuamous cell carcinoma (<*
b* 2asal cell carcinoma ("*
c* <elanoma - skin (any site* (<*
3/. "iseases of Endocrine organs
a* 2reast - fibroadenoma (<*
b* 2reast - carcinoma (<*
c* Thyroid - multinodular goitre (<*
d* Thyroid - solitary nodule 4 adenoma (<*
f. .ooks recommended"
a* Text book of athology by %obbins
b* Text book of 5eneral athology art $ + $$ by 2hende and "eodhare
c* Clinical athology by Talib
d* Text book of athology by 7arsh <ohan
e* Text book of athology by <uir
f* 7aematology "e 5ruchi
g* $A< text book of athology
/eference books"
a* Anderson@s text book of athology )ol $ + $$
b* 9xford text book of athology )ol. $, $$ + $$$
c* athology by %ubin and Darber
d* athologic basis of "isease %obbins
#. Evaluation
a.-ethods
Theory, racticals and )iva
b.!attern of Theor% ,0amination including 1istribution of -arks# 2uestions#
Time.
,ature of ?uestion Pa&er
3acult% with
+ear
" S,&(41 -..S
Sub5ect " P-!2+/+G3
!a$er " I
Total -arks " 67 Tim
e
" 8 'ours
Section @-@ 5; Mar%s.
Instructions47
-* Dill (dark* the appropriate empty circle below the Cuestion number once only..
3* #se blue9blac% ball point pen only.
&* Each Cuestion carries one 9 half "ar%.
(. Students $ill not be allotted "ar% if he9she over$rites stri%es or &ut $hite in% on the cross
once "ar%ed.
/* "o not write anything on the blank portion of the Cuestion paper. $f written anything, such type of
act will be considered as an attempt to resort to unfair means.
Section @-@ 4 MC? 5; "ar%s.
Huestion =o. Huestion "escription "ivision of <arks Total <arks
-. Total <CHs ; -? -? I J .0
Section @B@ A @C@ 52 Mar%s.
Instructions47
-* All Cuestions are compulsory.
3* The number to the right indicates full marks.
&* "raw diagrams wherever necessary.
(. -ns$er each section in the res&ective ans$erboo% only. -ns$ers $ritten in the ina&&ro&riate
sectional ans$er boo%s $ill not be assessed in any case.
/* "o not write anything on the blank portion of the Cuestion paper. $f written anything, such type of act
will be considered as an attempt to resort to unfair means.
Section @B@ 4 B-? 52' Mar%s.
Huestion =o. Huestion "escription "ivision of <arks Total <arks
3. Brief ans$er Buestions
5-tte"&t any five out of siC.
a* b* c* d* e* f*
/ I 8 3.
Section @C@ 4 /-? 512 Mar%s.
Huestion =o. Huestion "escription "ivision of <arks Total <arks
&. -tte"&t any t$o out of three4
Long answer question onl%
a* b* c*
3 I ? -3
3acult% with +ear " S,&(41 -..S
Sub5ect " P-!2+/+G3
!a$er " II
Total -arks " 67 Time " 8 'ours
Section @-@ 5; Mar%s.
Instructions47
-* Dill (dark* the appropriate empty circle below the Cuestion number once only..
3* #se blue9blac% ball point pen only.
&* Each Cuestion carries one 9 half "ar%.
(. Students $ill not be allotted "ar% if he9she over$rites stri%es or &ut $hite in% on the cross
once "ar%ed.
/* "o not write anything on the blank portion of the Cuestion paper. $f written anything, such type of
act will be considered as an attempt to resort to unfair means.
Section @-@ 4 MC? 5; "ar%s.
Huestion =o. Huestion "escription "ivision of <arks Total <arks
-. Total <CHs ; -? -? I J .0
Section @B@ A @C@ 52 Mar%s.
Instructions47
-* All Cuestions are compulsory.
3* The number to the right indicates full marks.
&* "raw diagrams wherever necessary.
(. -ns$er each section in the res&ective ans$erboo% only. -ns$ers $ritten in the ina&&ro&riate
sectional ans$er boo%s $ill not be assessed in any case.
/* "o not write anything on the blank portion of the Cuestion paper. $f written anything, such type of act
will be considered as an attempt to resort to unfair means.
Section @B@ 4 B-? 52' Mar%s.
Huestion =o. Huestion "escription "ivision of <arks Total <arks
3. Brief ans$er Buestions
5-tte"&t any five out of siC.
a* b* c* d* e* f*
/ I 8 3.
Section @C@ 4 /-? 512 Mar%s.
Huestion =o. Huestion "escription "ivision of <arks Total <arks
&. -tte"&t any t$o out of three4
Long answer question onl%
a* b* c*
3 I ? -3
)irection47 +nly short ans$er Buestions "ay be &er"itted fro" the &ortions
"ar%ed as @)esirable to %no$@
c. !a$er wise distribution of theor% to$ics and number of questions"
A*
aper $;- 5eneral athology inclusive of general neoplasia
7aematology inclusive of transfusion medicine.
9ut of & :AHs in 'ection C, 3 Cuestions should be from 5eneral athology and
5eneral =eoplasia and one Cuestion should be from 7aematology inclusive of
transfusion medicine.
2*
aper $$;- 'ystemic athology inclusive of systemic =eoplasia and Clinical
athology.
9ut of & :AHs in 'ection C, 3 Cuestions should be from 'ystemic athology and
'ystemic =eoplasia and one Cuestion should be from Clinical athology.
d. -arking scheme
Each paper of 8. marks as shown in the above table.
e. 4ature of $racticals and duration
Practicals Mar%s 28
a. -. 'pots 3 minutes each (8 specimen,
- instrument, & histopathology -.
slides, - haematology slide and - chart*
$dentification - -43 mark together - mark for
'pecific short Cuestion - -43 mark each spot
b. #rine Examination - hysical and two abnormal constituents ./
c. 7istopathology slides ; "iagnosis and discussion .&
d. 7aematology examination
i* eripheral blood smear stain and report .&
ii* 7b4T:C42lood group ./
------
Total 3?
777777
f. 9i:a " duration and to$ic distribution
*iva consists of t$o tablesD on each table the student $ill
face 2 eCa"iners for # "inutes each 4
!able 7 I General and Syste"ic Pathology 7 :
"ar%s
Table - $$ Clinical athology and 7aematology - 6 marks
!otal 1( "ar%s
,u"ber of Students for Practical ECa"ination should not eCceed "ore than ' 9
day
5( for general PathologyE ( for Syste"ic PathologyE : for Clinical Pathology
including he"atology.
g. !lan for internal assessment
The time table for internal assessment will be as follows ;
Theory -/
ractical -/
Scheme of internal assessment
<ro" the batches $hich have joined before =une 2''1
ECa"ination Se"ester9ter" $ise !otal ,o
2ead distribution of "ar%s
Theory $$$ 'emester
a*. <id-term test (<CH* &.
single best response
b*. $$$ 'emester examination 0.
$) 'emester
a*. <id-term (<CH* &.
single best response
b*. $) 'emester examination 0.
) 'emester
a*. relims examination 0.
--------------
Total theory &..
(reduced to out of -/*
7777777777777
racticals $$$ 'emester examination 8.
$) 'emester examination 8.
relims examination 8.
----------
Total racticals -3.
(reduced to out of -3*
----------
Fournal Kear ending .&
Total internal assessment &.
<ro" the batches joining in =une 2''1 and later
ECa"ination Se"ester9ter" $ise !otal ,o
2ead distribution of "ar%s
Theory $$$ 'emester
Term ending examination /.
$) 'emester
Term ending examination /.
) 'emester
a*. relims examination 0.
--------------
Total theory -0.
(reduced to out of -/*
7777777777777
racticals $$$ 'emester examination 8.
$) 'emester examination 8.
relims examination 8.
----------
Total racticals -3.
(reduced to out of -3*
----------
Fournal Kear ending .&
Total internal assessment &.
*th se"ester
relims examination on the basis of #niversity pattern (Theory, practical and viva* ;
<inimum 8 weeks gap between relims and #niversity examination.
Dor the terminal theory examination 30 <CHs (-43 mark each*, -. 'AHs (option of
-. of any -3B 3 marks each* and 3 :AHs (option of 3 of any &B 0 marks each* will be
administered. The total time will be 3 hours &. mins. This will be followed by
practicals (total time - J hours*. To familiari>e the students with the LvivaE
methodology, the marks for the practical may be kept 3. while 3. marks may be
given for the viva on theory topics (total 8. marks*.
relim pattern will be as per the #niversity exam with 3 papers in theory, each of 3
hours duration.
2. MIC1+BI+/+G3
;. *oal
The goal of teaching Microbiology is to provide understanding of the natural
history of infectious diseases in order to deal with the etiology, pathogenesis,
pathogenicity, laboratory diagnosis, treatment, control and prevention of these
infections and infectious diseases.
8. ,ducational ob5ecti:es
5a. Fno$ledge
The student at the end of one and half years should be able to: -
i. state the etiology, pathogenesis and methods of laboratory diagnosis and
apply that knowledge in the diagnosis, treatment, prevention and control of
communicable diseases caused by microorganisms.
ii. understand commensal, opportunistic and pathogenic organisms of human body
and describe host parasite relationship.
iii. know and describe the pathogenesis of diseases caused by microorganisms.
iv. state the sources and modes of transmission of pathogenic and opportunistic
micro-organisms including knowledge of insect vectors + their role in
transmission of infectious diseases.
v. choose appropriate laboratory investigations reCuired for clinical diagnosis.
(b) Skills
i. plan and interpret laboratory investigations for diagnosis of infectious diseases
and correlate the clinical manifestations with the etiological agent.
ii. identify common infectious agents with the help of laboratory procedure, acCuire
knowledge of antimicrobial agents, use of antimicrobial sensitivity tests to select
suitable antimicrobial agents for treatment.
iii. perform simple laboratory tests, which help to arrive at rapid diagnosis.
iv. be conversant with proper methods of collection, storage + transport of clinical
material for microbiological investigations.
v. understand the principles of immunology and its application in the diagnosis and
prevention of infectious diseases including immuni>ation schedule, acCuire
knowledge of the scope of immunotherapy and different vaccines available for the
prevention of communicable diseases.
vi. understand methods of disinfection and sterili>ation and their application to
control and prevent hospital and community acCuired infections including
universal biosafety precautions and waste disposal.
vii. recommend laboratory investigations regarding bacteriological examination of
food, water, milk and air.
viii.the student should be well eCuipped with the knowledge of prevalent
communicable diseases of national importance and of the newer emerging
pathogens.
(c) )ttitude

i. the student will be regular, sincere, punctual and courteous and regular in studies.
ii. the student will follow all the rules laid down by the department and participate in
all activities.
iii. the student will understand the importance of, and practice asepsis, waste
segregation and appropriate disposal.
iv. the student will understand the importance of, and practice the best methods to
prevent the development of infection in self and patient. (E.g. hand washing, using
aprons for hospitals in hospitals only, regularly washing the aprons, wearing
gloves (as and when reCuired 4 handling specimens etc.*.
v. the student will understand the use of the different antimicrobial agents including
antibiotics to use !udiciously and prevent misuse, (prescribing attitude*.
vi. the student will understand the significance of vaccinations and will receive
appropriate vaccines (e.g. TT, 7epatitis 2 and any other as per
needs*.
vii. the student will wash his4her hands with soap after each practical class.
viii.the student will leave the area allotted for his practical neat and tidy.
ix. the student will discard the slides in the appropriate container provided for the
same.
x. the student will report any in!ury sustained in class, immediately.
xi. the student will report any breakage occurring during class times immediately.
xii. the student may give suggestions to improve teacher student association.
. !otal duration of &ara7clinical teaching & semesters
Total &?. teaching days
!otal nu"ber of teaching hours allotted for Microbiology 2#' hrs
5-s &er MCI guidelines 1GG:..
(. Syllabus
a. Learning methods
:ectures, practicals
"istribution of teaching hours
A* Theory (lectures + ,.. 6-
(tutorials ,.. 3?
----------------------------------------
Total ,.. G:
2* racticals and %evision ,.. -3.
C* Assessments ,.. &&
--------------------------------------------------------------------------------------
Total ,.. 3/.
b. & c. Sequential organisation of contents and their di:ision
The areas of study in <icrobiology will include 5eneral <icrobiology, 'ystemic
<icrobiology including 2acteriology, $mmunology, <ycology, )irology, %ickettsia,
Chlamydia, arasitology and Applied microbiology in relation to infections and
diseases of various systems of the body.
-. GE,E1-/ MIC1+BI+/+G34 5n61'.
4o To$ic of
lecture
-ust know (-K) )esirable to
%no$ 5)F.
'rs
-. $ntroduction
and 7istorical
background
"efinitions; <edical <icrobiology, pathogen,
commensal, symbiont etc. To cover Anton van
:eewenhoek, asteur, :ister, Aoch, Dlemming etc. $n
7istory; 'cope to cover the importance of <ed.
<icrobiology on diagnosis and prevention of infectious
diseases.
<icro-organisms
as models in
<olecular 2iology
and 5enetic
engineering.
-
3. <orphology
of bacteria
and
Classification
2acterial cell and its organelles, morphological
classification, methods of studying bacteria, staining
methods + their principles
5rams + Meil =elson staining, their importance in
presumptive diagnosis, negative staining, dark ground
illumination, phase contrast and fluorescent microscopy,
briefly about electron microscopy. rinciples and
applications of all microscopes.
-
&. hysiology of
bacteria
including
growth
reCuirements
+ metabolism
=utrition, respiration (anaerobic + aerobic* and growth
of bacteria, growth curve, physical factors influencing
growth. Culture media; "efinition, classification and
application.
$mportant
constituents of
culture media.
-
8. 'terili>ation "efinition of sterili>ation, disinfection, asepsis,
antiseptics. #biCuity of bacteria, modes of killing
microbes and preventing them, factors determining
selection of the mode, factors adversely affecting
sterili>ation. Enumeration of physical methods of
sterili>ation including principle + their application.
Gorking and
efficacy testing of
autoclave,
inspissator and hot
air oven.
Central 'terile
'upply
"epartment
(C''"* N concept
only.
-
/. "isinfectants Asepsis and antisepsis, modes of
Action of chemical agents on microbes. henols,
7alogens, Aldehydes, Acids, Alcohol, heavy metals,
oxidi>ing agents etc. #niversal biosafety precautions.
"yes, soaps and
detergents.
Concentration and
contact time.
-
?. Gaste
disposal
"efinition of waste, classification, segregation, transport
and disposal.
-
6. 2acterial
genetics and
drug
resistance to
antimicrobial
agents.
$ntroduction N codon, lac operon, mutation,
transformation, transduction + con!ugation, % factor,
mode of action of antimicrobials on bacteria, mechanism
of drug resistance and antimicrobial susceptibility tests,
steps taken to minimi>e emergence of resistant strains
(Antibiotic policy, formulation*,
-
0. 7ost parasite
relationship
and bacterial
infections
Commensal, pathogenic and opportunistic organisms,
their pathogenic factors and modes of transmission.
<icrobial factors; spores, capsule, toxins, en>ymes,
intracellular parasitism, antigenic variation + extrinsic
factors etc. leading to establishment of infection. Types
of infection; primary, secondary, general, local, natural,
nosocomial, iatrogenic, >oonotic.
-
1. =ormal flora $ntroduction N various sites, types and role -
-.. <ethods of
identification
of bacteria.
"iagnosis of
infectious
diseases
( direct and
indirect*
rinciples of laboratory diagnosis of infectious diseases.
5eneral procedures for collection transport, processing of
specimens for microbiological diagnosis.
C%, %$A, "=A
probes.
-
B. IMM0,+/+G34 5n612.
,o. !o&ic Must %no$ )esirable to %no$ 2rs
- $ntroduction "efinition of immunity, types of immunity,
factors responsible, mechanism of innate
immunity, active and passive immunity, local
immunity.
7erd immunity -
3 Antigens, 7:A "efinition, types, antigen determinants,
properties of antigen.
<7C- concept, class- $, $$ + $$$ functions,
indication of typing, <7C restriction.
=ature of determinants,
e.g. of haptens, e.g. of
cross- reactive antigen.
-
& Antibodies "efinition, nature, structure of immuno-
5lobulins, papain digestion, understand
isotypic, allotypic and idiotypic markers,
immunoglobulin classes, physical and
biological properties of immunoglobins.,
epsin digestion, amino
acid seCuence,
immunoglobin domain,
abnormal immunoglobins.
-
8 'erological
reactions
"efinition, characteristics, titre, sensitivity +
specificity, antigen- antibody interaction-
primary, secondary + tertiary, pro>one
phenomenon, principle, types and application
of precipitation, agglutination, complement
fixation, en>yme immunoassay,
radioimmunoassay, immunofluoroscence test,
neutrali>ation and opsonisation.
TechniCues of precipitation
and their uses, blocking
antibodies, antiglobulin
reactions, co-agglutination,
in vitro test, techniCues of
E$A, $D + electron
microscopy.
3
/ $mmune
response
Types, development, role of --thymus, bone
marrow, lymph nodes + spleen, cells of
lymphoreticular system, morphology and role
of T subsets, =A cells, 2 cells , plasma cells
and macrophages, 2 + T cell activation,
antigen processing and presentation, primary
and secondary immune response, principle
and uses of monoclonal antibodies, factors
affecting antibody production, C<$-
definition, types, role of T cell and
macrophages, definition of immune tolerance
and mechanism of tolerance.
:ymphokines and their
role, clonal selection,
mechanism of
immunoregulation, theories
of antibodies formation,
techniCues of monoclonal
antibody formation,
detection of C<$, types of
immunotolerance.
3
? Complement "efinition, synthesis, pathways, activation,
role + biological functions, components,
measurement.
%egulation of complement
activation, complement
deficiency
-
6 7ypersensitivity "efinition, classification, , difference between
immediate and delayed reaction, mechanism
of anaphylaxis, manifestations of anaphylaxis,
types of anaphylaxis, atopy, e.g. of
anaphylactic reaction, tests for anaphylaxis,
mechanism and e.g. of type-$$ + type-$$$
reactions, mechanism + types of delayed
hypersensitivity.
"esensiti>ation in
anaphylaxis, type )
reaction, A"CC,
'hwart>man phenomenon.
-
0 Autoimmunity "efinition, mechanism, classification,
pathogenesis.
-
1 Transplantation
+ tumour
immunology
Types of transplants, mechanism of transplant
re!ection, prevention of graft re!ection, 5)7
reaction, $% to tumours, tumour antigens,
mechanism of $% to tumours.
Type of tumour antigens,
immune surveillance.
-
-.. $mmuno-
"eficiency
Classification, examples, laboratory tests for
detection, manifestations.
-
C* 'K'TE<$C 2ACTE%$9:95K; (nO3-*
Pathogenesis includes4
$nfectious agent - <A PMK- Must know
7abitat - <A PK- esirable to know
'ource 4 reservoir - <A
<ode - <A
$nfective dose - <A
<ultiplication, spread - <A
Clinical features, pathology - <A
Complications - <A
)irulence factors - <A
$mmunological response - "A
/aboratory diagnosis4 -<A
'pecimen selection -<A
Collection -<A
Transport -<A
rimary smear, hanging drop -<A
'election of media -<A
athogenicity testing -<A
Anti microbial drug susceptibility testing-<A
'erological interpretation -<A
Aey to the abbreviations used in the table below;
A-Classification, B- <orphology, C- Culture and isolation, )- 2iochemical
reactions,
E- )iability, < -)irulence, G- "iseases, 2- Antigens, I- athogenesis, =- :aboratory
diagnosis, F- revention and control, /- $mmune response
=o !o&ic9 hours - B C ) E < G 2 I = F /
- 'taphylococci
(- hour*
<A <A "A "A <A <A <A "A <A <A <A -
3 'treptococci
neumococci
(- hour*
<A <A 2A-<A,
"A
"A <A <A <A <A <A <A <A "A
& =eisseria
(- hour*
"A <A "A "A <A <A <A "A <A <A <A -
8 C.diptheriae
(- hour*
"A <A "A - <A <A <A - <A <A <A "A
/ <.Tuberculosis
(- hour*
<A <A :F,5rowth
Time <A
"A <A <A <A <A <A <A <A "A
? Atypical
mycobacteria
(-hour*
<A <A "A "A <A <A <A - <A <A <A -
6 <.leprae
(- hour*
<A <A $solation-
<A
- <A <A <A <A <A <A <A <A
0 2acillus
<ethods of
anaerobiosis +
classification.
=on sporing
anaerobes
(- hour*
<A <A <A "A <A <A <A - <A <A <A -
1 Clostridium
welchii, tetani,
botulinum
(- hour*
<A "A <A - - - <A - - <A - -
-. Enterobacteriacea
e
( - hour*
<A <A "A "A <A <A <A "A - <A - -
-- 'almonella typhi
(- hour*
<A <A "A "A <A <A <A "A - <A - <A
-3 'higella (- hour* <A <A "A "A <A <A <A "A - <A - -
-& )ibrio +
Campylobacter
(- hour*
<A <A "A "A <A <A <A - - <A - -
-8 seudomonas
(- hour*
- <A "A "A <A <A <A - - <A - -
-/ 9ther 5=2 (-
hour*
:ist
onl
y
<A "A - - <A - - - <A - -
-? =ewer bacteria
(- hour*
:ist
onl
y
<A "A - - - - - - <A - -
-6 'pirochete (-
hour*
<A <A "A - <A - <A - - <A - "A
-0 Actinomycosis +
=ocardia (- hour*
"A <A "A - - - - - - <A - -
-1 %ickettsia (-
hour*
<A <A - - - - - - - <A - -
3. Chlamydia +
<ycoplasma
(- hour*
<A <A - - - - - - - <A - -
3- 2acteriology of
air, water, milk
and food (- hour*
- - <A "A <A <A <A - <A <A <A -
). M3C+/+G34 5n6(.
,o !o&ic Must %no$ )esirable to %no$ 2rs
- $ntroduction to
<ycology
=ature of fungus (definition, differences
with bacteria*, characteristics of fungi,
common terminologies, brief account of
types of sporulation and morphological
classification of fungi. <ethods of
identification , $nfections produced,
:ab "iagnosis, processing of skin, hair
and nail,
5rowth reCuirements,
ecological, medical and
industrial importance of
fungi ( brief account*.
-
3 Agents of
'uperficial mycosis
Enumerate, predisposing factors,
morphological features, :ab. "iagnosis
Colony characteristics
of dermatophytes
-
& 'ubcutaneous
mycosis
Enumerate, predisposing factors,
<ycetoma, %hinosporidiosis,
athogenesis, :ab. "iagnosis
- -
8 'ystemic mycosis
9pportunistic fungal
infections
Classification, predisposing factors,
Candida, Cryptococcus, 7istoplasma
morphology, pathogenesis, lab.
"iagnosis
Classification, predisposing factors,
<ucor, Aspergillus, neumocystis carinii
Cultural characteristics -

E. *I1+/+G34 5n612.
<orphology, pathogenesis, laboratory diagnosis, prevention and control for all viruses
(<ust know*.
,o !o&ic of lecture -ust know )esirable to
%no$
2rs
- 5eneral )irology 'i>e, shape, symmetry, structure, resistance,
multiplication, properties and classification of
viruses, pathogenesis, bacteriophages, concept of
virons
- -
3 :aboratory diagnosis
of viral infections
Collection of samples, transport, cultivation and
methods of diagnosis
- -
& )iral immunity )iral immunity, interferon, viral vaccines - -
8 ox viruses 'mall pox and <olluscum - -
/ "=A viruses apova, Adeno, 7erpes viruses ( 7erpes simplex,
)aricella >oster, C<), E2)*
- -
? %espiratory viruses 9rthomyxo and aramyxoviruses, Ag shift and drift %hinoviruses -
6 icornaviruses olio, Coxsackie, Enteroviruses, )iruses causing
diarrhoea N %ota viruses, $mmunity (polio*
- -
0 7epatitis viruses 7epatitis viruses , immunity and laboratory diagnosis - -
1 Arboviruses "engue, AD", Fapanese encephalitis N definition,
classification, enumeration in $ndia, athogenesis,
laboratory diagnosis and control
- -
-. %habdoviruses %abies - -
-- 'low and 9ncogenic
viruses
Characteristics of slow virus infections, pathogenesis
and laboratory diagnosis and viruses associated with
it
- -
-3 %etroviruses 7$)4A$"', $mmunity, #' - -
D* A%A'$T9:95K; (nO--*
Must %no$ N
5eographical distribution
7abitat
<orphology ( different stages * found in human beings
:ife cycle
athogenesis
:aboratory diagnosis
Treatment
Control
$mmunoprophylaxis
,o !o&ic of lecture Must %no$ )esirable to
%no$
2rs
- $ntroduction to
medical
arasitology
arasites; their nature, classification, and explanation
of terminologies, epidemiology, emerging parasitic
infections, (pathogenicity and laboratory diagnosis*
-
3 E. histolytica Amoebic infections -
& Dree living
amoebae and
flagellates
Dree living amoebae, A<E, 5iardia + Trichomonas -
8 7emoflagellates :. donovani; life cycle, morphology, pathogenicity,
and lab. "iagnosis etc.
2rief account of
Trypanosomes
-
/ <alaria <alarial parasites; life cycle, morphology,
pathogenicity, laboratory diagnosis etc.
-
? <isc. athogenic
proto>oa
Toxoplasma, Cryptosporidium,
$sospora, 2.coli
-
6 Cestodes Taenia saginata + solium, Echinococcus granulosus,
life cycle, morphology, pathogenicity and laboratory
diagnosis.
2rief mention of
other cestodes
-
0 Trematodes 'chistosomiasis; life cycle, morphology, pathogenicity
+ lab diagnosis.
2rief account of
Dasciola hepatica
-
1 $ntestinal
=ematodes
A.duodenale, A. lumbricoides, E. vermicularis, T.
tritura
brief mention of
'. stercoralis, life
cycle,morphology
laboratory
diagnosis
3
-. Tissue
=ematodes
G. bancrofti, ". medinensis, in brief T. spiralis -
!0!+1I-/S 5-PP/IE) MIC1+BI+/+G3. 4 5n628.
1egular tutorialsE student se"inars A sy"&osia shall be conducted in addition to
lectures.
Students "ust %no$4
<icro-organisms causing diseases + pathological lesions
<ethods of collection + transportation of specimens
<ethods of laboratory diagnosis
'erological response produced by organisms
$nterpretation of laboratory report
,o !o&ic of !utorial 2rs
- 5astrointestinal infections ( diarrhoea and dysentery* and their laboratory diagnosis 3
3 #pper respiratory tract infection ( patch and sore throat* and their laboratory diagnosis 3
& :ower respiratory tract infection ( pneumonia, bronchitis, bronchiolitis etc.* and their
laboratory diagnosis
3
8 #rinary tract infection and their laboratory diagnosis 3
/ $nfections of the central nervous system ( meningitis, encephalitis, brain abscess* and their
laboratory diagnosis
3
? Gound infections and pyogenic infections 3
6 'epticemia and laboratory diagnosis and #9 3
0 Eye infections and their laboratory diagnosis 3
1 'exually transmitted disease ('T"* and their laboratory diagnosis ( genital ulcerative disease* 3
-. %ole of laboratory in cross infection, =osocomial infections 4 outbreak 4 epidemic 3
-- )ehicles and vectors of communicable disease + >oonosis 3
-3 reventive inoculations, immunomodulation and immunotherapy 3
Suggested to$ics for integrated teaching:
Tuberculosis and :eprosy =ote; Each topic may be allotted &
hours. These topics may
yrexia of #nknown 9rigin ( #9 * be covered in 3
nd
and &
rd
term of 3
nd
<22'.
'exually Transmitted "iseases
7epatitis
7$) 4 A$"'
<alaria
"iarrhoea and "ysentery
d. Termwise distribution
Dirst term (8 months* Theory- &3 hours ractical- &3 hours
'econd term (/ J months* Theory- ?? hours ractical- 88 hours
Third term (8 months* Theory- 80 hours ractical- &3 hours
!otal teaching hours 2#( hours
S%stemwise distribution
!E1M B1+-) !+PICS
,+. +< C/-SSES
:ectures
(- hour*
racticals
(3 hours*
!0!+1I-/S
(3 hours*
<irst ter" 5eneral <icrobiology -. 30 -
'ystemic 2acteriology -0 38 -
Second ter" 'ystemic bacteriology & -1 7
$mmunology -3 8 7
)irology -3 8 7
<ycology / 8 7
arasitology -- 38 7
!hird ter" Applied microbiology - - 3?
e. !racticals " Total hours# number & contents ; (nO-..*
,o !o&ic 2rs
-. $ntroduction to <icrobiology, <icroscopy and <icrometry. 8
3. <orphology and physiology of bacteria and methods staining. 8
&. 5rowth reCuirements of bacteria (media* and identification of bacteria (biochemical reactions*. 8
8. 'cheme for laboratory diagnosis of infectious diseases and collection, storage and transport of
microbiological specimens and laboratory animals.
8
/. 'terili>ation- the physical agents.
'terili>ation- the chemical agents and method of waste disposal.
8
?. 'erological tests for diagnosis of microbial infections. 8
6. 'taphylococci and other gram-positive cocci. 8
0. 'treptococci and neumococci. 8
1. 5ram negative cocci 8
-.. C. diphtheriae and other gram positive non sporing bacilli 8
--. <ycobacteria 8
-3. 'pore bearing aerobic and anaerobic bacilli. 8
-&. Enteric gram-negative bacilli N lactose fermenters - E.coli etc 8
-8. =on lactose fermenters N 'almonella and 'higella 8
-/. ). cholerae and other )ibrio like organisms 8
-?. 9ther gram-negative bacilli including seudomonas, roteus and hospital acCuired infection. 8
-6. 'pirochetes 8
-0. Actinomycetes, =ocardia and Dungi. 8
-1. %ickettsia, Chlamydia, <ycoplasma and )iruses 8
3.. $ntroduction to arasitology and roto>oal infections (including $sospora + Cryptosporidium* 8
3-. 7aemoflagellates 8
33. lasmodia and toxoplasma. 8
3&. Cystodes and trematodes 8
38. $ntestinal nematodes 8
3/. Extra-intestinal nematodes. 8
The number of practicals and lectures can be changed as per the needs.
$ntroduction 9f Q2io-<edical GasteR topic in sub!ect of <icrobiology + reventive
+ 'ocial <edicine
f. .ooks recommended"
-. Textbook of <icrobiology - !. "nanthanarayan
#. K. $ayaram %anikar
3. A Textbook of <icrobiology - %. #hakraborty
&. Textbook of <edical <icrobiology - !a&esh 'hatia ( )tchpu&ani
8. Textbook of <edical <icrobiology - "rora and "rora
/. Textbook of <edical arasitology - #. K. $ayaram %anikar
?. Textbook of <edical arasitology - "rora and "rora
6. Textbook of <edical arasitology - S.#.%ari&a
0. <icrobiology in clinical practice - . #. Shanson
" Te*tbook of %arasitology - r. !.%. Karyakarte and r. ".S.
amle
/eference books"
-. <ackie <cCartney practical <edical <icrobiology- #olle $+ , ,raser "+
3. rinciples of 2acteriology, )irology +
$mmunology vol. -,3,&,8,/- Topley -ilsons
&. <edical <ycology (Emmons*- Kwon . #hung
8. %eview of <edical <icrobiology (:ange*- $awet/
/. $mmunology- -eir M
?. <edical <icrobiology- avid +reenwood, !ichard Stack, $ohn %entherer

6. arasitology- K #hatter&ee
0. <edical virology- Timbury M#
1. <ackie <cCartney <edical, <icrobiology vol.-- uguid $%
-..<icrobial infections- Marmion '%, Swain !0"
#. Evaluation
a. Methods
Theory, ractical + )iva
,o !otal "ar%s
- Theory ( 3 papers N 8. marks each* 0.
3 9ral ()iva* -/
& ractical 3/
8 $nternal assessment ( theory N-/, practicals N-/* &.
!+!-/ 1#'
Passing 4 A candidate must obtain /.S in aggregate with a minimum of /.S in
Theory including oral and minimum of /.S in practicals and /.S in internal
assessment (combined theory and practical*.
b. !attern of Theor% ,0amination including 1istribution of -arks# 2uestions#
Time.
,ature of ?uestion Pa&er
3acult% with
+ear
" S,&(41 -..S
Sub5ect " MIC1+BI+/+G3
!a$er " I
Total -arks " 67 Tim
e
" 8 'ours
Section @-@ 5; Mar%s.
Instructions47
-* Dill (dark* the appropriate empty circle below the Cuestion number once only..
3* #se blue9blac% ball point pen only.
&* Each Cuestion carries one 9 half "ar%.
(. Students $ill not be allotted "ar% if he9she over$rites stri%es or &ut $hite in% on the cross
once "ar%ed.
/* "o not write anything on the blank portion of the Cuestion paper. $f written anything, such type of
act will be considered as an attempt to resort to unfair means.
Section @-@ 4 MC? 5; "ar%s.
Huestion =o. Huestion "escription "ivision of <arks Total <arks
-. Total <CHs ; -? -? I J .0
Section @B@ A @C@ 52 Mar%s.
Instructions47
-* All Cuestions are compulsory.
3* The number to the right indicates full marks.
&* "raw diagrams wherever necessary.
(. -ns$er each section in the res&ective ans$erboo% only. -ns$ers $ritten in the ina&&ro&riate
sectional ans$er boo%s $ill not be assessed in any case.
/* "o not write anything on the blank portion of the Cuestion paper. $f written anything, such type of act
will be considered as an attempt to resort to unfair means.
Section @B@ 4 B-? 52' Mar%s.
Huestion =o. Huestion "escription "ivision of <arks Total <arks
3. Brief ans$er Buestions
5-tte"&t any five out of siC.
a* b* c* d* e* f*
/ I 8 3.
Section @C@ 4 /-? 512 Mar%s.
Huestion =o. Huestion "escription "ivision of <arks Total <arks
&. -tte"&t any t$o out of three4
Long answer question onl%
a* b* c*
3 I ? -3
3acult% with +ear " S,&(41 -..S
Sub5ect " MIC1+BI+/+G3
!a$er " II
Total -arks " 67 Time " 8 'ours
Section @-@ 5; Mar%s.
Instructions47
-* Dill (dark* the appropriate empty circle below the Cuestion number once only..
3* #se blue9blac% ball point pen only.
&* Each Cuestion carries one 9 half "ar%.
(. Students $ill not be allotted "ar% if he9she over$rites stri%es or &ut $hite in% on the cross
once "ar%ed.
/* "o not write anything on the blank portion of the Cuestion paper. $f written anything, such type of
act will be considered as an attempt to resort to unfair means.
Section @-@ 4 MC? 5; "ar%s.
Huestion =o. Huestion "escription "ivision of <arks Total <arks
-. Total <CHs ; -? -? I J .0
Section @B@ A @C@ 52 Mar%s.
Instructions47
-* All Cuestions are compulsory.
3* The number to the right indicates full marks.
&* "raw diagrams wherever necessary.
(. -ns$er each section in the res&ective ans$erboo% only. -ns$ers $ritten in the ina&&ro&riate
sectional ans$er boo%s $ill not be assessed in any case.
/* "o not write anything on the blank portion of the Cuestion paper. $f written anything, such type of act
will be considered as an attempt to resort to unfair means.
Section @B@ 4 B-? 52' Mar%s.
Huestion =o. Huestion "escription "ivision of <arks Total <arks
3. Brief ans$er Buestions
5-tte"&t any five out of siC.
a* b* c* d* e* f*
/ I 8 3.
Section @C@ 4 /-? 512 Mar%s.
Huestion =o. Huestion "escription "ivision of <arks Total <arks
&. -tte"&t any t$o out of three4
Long answer question onl%
a* b* c*
3 I ? -3

-. MIC1+BI+/+G3 P-PE1 I
5eneral <icrobiology
'ystematic bacteriology including %ickettsia, Chlamydia and <ycoplasma
%elated applied microbiology.
B. MIC1+BI+/+G3 P-PE1 II
arasitology
<ycology
)irology
$mmunology
%elated applied <icrobiology.
d. -arking scheme
Each paper of 8. marks as shown in the above table.
e. 4ature of $racticals and duration
ractical examination in <$C%92$9:95K will be of 3? marks and oral (viva* of -8
marks of T7%EE hours duration.
H.-; 5ram staining /
H.3; Meil N =elsonEs staining /
H.&; 'tool examination for 9va4cyst ?
H.8; 'pot identification (Ten spots*P -.
!otal7 28
(P'pots- <icroscopic slides, <ounted specimen, $nstruments used in laboratory,
'erological tests, $noculated culture medium, 'terile culture medium, )accines 4
serum*.
f. 9i:a (Two tables* <arks
A; 5eneral + 'ystemic <icrobiology 6
2; <ycology, arasitology, )irology, $mmunology 6
g. !lan for internal assessment
<arks for $nternal Assessment;
Theory; -/
ractical; -/
<ro" the batches $hich have joined before =une 2''1
!heory eCa"ination
$nternal assessment for theory shall be calculated on the basis of two term ending
examinations ($
st
+ $$
nd
*, two mid term examinations in $
st
+ $$
nd
term + one
preliminary examination at the end of the course (total / examinations* till the batch
of =ov.3... admission appears for #niversity examination.
Mar%s )istribution for theory eCa"ination4 5Internal assess"ent.
ECa"ination MC? S-? /-?
Mar%s ,o. Mar%s ,o. Mar%s ,o.
!otal !i"e
$st + $$nd
midterm
-. 3. 3. -.4-3 - - &. - hr
$st + $$nd
term
30 /? 38 -34-8 30 84/ 0. & hr
<CH O <ultiple choice Cuestions, 'AH O 'hort answer Cuestions, :AH O :ong
answer Cuestions
reliminary examination (as per the #niversity pattern N 3 papers, & h each* 0.
marks
$nternal assessment marks for theory will be computed to -/ out of total &.. marks.
Practicals 5Internal assess"ent.4
Three term ending practicals only.
Mar%s )istribution of Practicals;
$
st
term ending examination 8.
$$
nd
term ending examination 8.
reliminary ractical examination 8.
!otal7 12'
$nternal assessment marks for racticals have to be computed out of -3 marks at the
end of the curriculum and add marks for !ournals out of &. Thus, total marks for
practical assessment will be -/.
<ro" the batches joining in =une 2''1 and later
attern for computation of @ $nternal Assessment @ in the sub!ect of <icrobiology.
( Applicable to the batch !oining in Fune 3..-*
T7E9%K;
$nternal assessment shall be computed on the basis of three term ending examinations
( two terminals + one preliminary examination before the university examination*.
EIA<$=AT$9= =o.of apers attern "uration of
each paper
Total
<arks
-
'T
TE%<$=A: 9ne -/. <arks <CHs- 30(-8 <arks*
'AHs- -.4-3 (3. <arks*
:AHs- 34& ( -? <arks*
3 7ours &.
<inutes
/.
3
="
TE%<$=A: 9ne - /. marks <CHs- 30(-8 <arks*
'AHs- -.4-3(3.<arks*
:AHs- 34& (-? <arks *
3 7ours &.
<inutes
/.
%E:$<$=A%K
(As per final
#niversity pattern*
Two - 8.
marks each
Each paper-
<CHs- 30(-8 <arks*
'AHs- ?46(-3<arks*
:AHs- 34& (-8 <arks*
(Total- 8. <arks, each paper*
3 7ours
each paper
0.
T9TA: -0.
Dinal internal assessment in T7E9%K shall be computed on the basis of actual marks
obtained out of -0., reduced to marks out of -/.
P1-C!IC-/4
$nternal assessment in %ACT$CA:' shall be computed on the basis of three term
ending examinations and the marks allotted to practical record book.
EIA<$=AT$9= ATTE%= <A%A' T9TA:
-
'T
TE%<$=A: Exercise(eg.5ram@s
'tain*
-.
'potting -.
)iva 3.
8.
3
="
Exercise4Exercises(eg
.5ram@s + M.=. 'tain*
-.
'potting -.
)iva 3.
8.
%$:$<$=A%K EIA<
As per #niversity
pattern
5ram@s 'tain /
Miehl-=eelson 'tain /
'tool Exam. /
'potting -.
)iva -/
8.
T9TA: -3.
Actual marks obtained out of -3. shall be reduced to out of -3. Add marks obtained
out of & for ractical %ecord 2ook. Total internal assessment marks for ractical shall
be out of (-3T&* -/.
Total $nternal Assessment ; Theory --- -/
ractical -- -/
--------
Total; &.
-------------------------------------------------------------------------------------------------------
-----------
Phar"acology and Phar"acothera&eutics
1. Goal
The broad goal of teaching pharmacology to undergraduate students is to inculcate in
them a rational and scientific basis of therapeutics.
2. Educational objectives
(a) Knowledge
At the end of the course, the student shall be able to -
i. describe the pharmacokinetics and pharmacodynamics of essential and commonly
used drugs
ii. list the indications, contraindications, interactions and adverse reactions of
commonly used drugs
iii. indicate the use of appropriate drug in a particular disease with consideration of its
cost, efficacy and safety for -
individual needs, and
mass therapy under national health programmes
iv describe the pharmacokinetic basis, clinical presentation, diagnosis and
management of
common poisonings
v $ntegrate the list the drugs of addiction and recommend the management
vi. Classify environmental and occupational pollutants and state the management
issues
vii. Explain pharmacological basis of prescribing drugs in special medical situations
such as pregnancy, lactation, infancy and old age
vii explain the concept of rational drug therapy in clinical pharmacology
viii state the principles underlying the concept of LEssential "rugsE
ix evaluate the ethics and modalities involved in the development and introduction
of new drugs
(b) Skills
At the end of the course, the student shall be able to -
i. prescribe drugs for common ailments
ii. identify adverse reactions and interactions of commonly used drugs
iii. interpret the data of experiments designed for the study of effects of drugs and
bioassays which are observed during the study
iv. scan information on common pharmaceutical preparations and critically evaluate
drug formulations
v. be well-conversant with the principles of pharmacy and dispense the medications
giving proper instructions

(c) Integration
ractical knowledge of rational use of drugs in clinical practice will be acCuired
through integrated teaching vertically with pre-clinical + clinical sub!ects and
hori>ontally with other para-clinical sub!ects.
. !otal duration of &ara7clinical teaching & 'emesters
($$$,$),)*
Total &?. teaching days
!otal nu"ber of teaching hours allotted to Phar"acology &.. hours
(. Syllabus
a. Learning methods
:ectures, tutorials, racticals
"istribution of teaching hours
Theor%
lectures .<<...;7= > ?
tutorials <<<.;@ > ?
!otal 128 H 1'
2* racticals ,,....-3. U /
C* %evision + Evaluation ($nternal Assessment* ,,,..?.
b. + c. 'eCuential organisation of contents + their division
A* $=T%9"#CT$9=; !harmacolog% a foundation to clinical $ractice
(=O-*
"evelopment of the branch of pharmacologyB 'cope of the sub!ectB role of drugs
as one of the modalities to treat diseases,
definition of drugB
nature and sources of drugsB
subdivisions of pharmacology
rational pharmacotherapy

B. GE,E1-/ P2-1M-C+/+G34 (=O6 U 3*
harmacokinetics; Absorption, "istribution, 2iotransformation, Elimination
(nO&* harmacodynamics; rinciples of "rug Action, <echanisms of drug
action,
%eceptors (=ature, Types, Theories, rinciples, %egulation* (nO-*
Application to pharmacotherapeutics; %elevance of harmacokinetics and dynamics
in clinical practice, 'eCuale of repeated administration of drug (nO3*
Adverse "rug %eactions (nO-*
C. -0!+,+MIC P2-1M-C+/+G34 (=O 0 U 3*
5eneral Considerations (nO-*
Adrenergic agonists (nO-*
Adrenergic antagonists $; V-blockers (nO-*
Adrenergic antagonists $$; W-blockers (nO-*
Cholinergic agonists (nO-*
Anticholinesterases (nO-*
Antimuscarinic drugs (nO-*
'keletal muscle relaxants (nO-*
-. C-1)I+*-SC0/-1 S3SEM I,C/0)I,G )10GS -<<EC!I,G
C+-G0/-!I+, -,) !2+SE -C!I,G +, FI),E3S4 (=O-8 U 3*
5eneral Considerations and 9verview of antihypertensive therapyB
"iuretics (nO3*
Angiotensin Converting En>yme (ACE* inhibitors (nO-*
'ympatholytics + vasodilators (nO-*
Management of hypertension
Antianginal; =itrates + others (nO-*
Calcium channel blockers (nO-*
%harmacotherapy of chest pain
Anticoagulants + Coagulants
Thrombolytics + Antiplatelet Agents (nO3*
)rugs for CC<4 )igitalis glycosidesE +thers agents 5n62.
Management of ##,
-ntiarrhyth"ic -gents 5n61.
-gents used for the "anage"ent of shoc% 5n61.
2y&oli&idae"ic drugs 5n61.
%ole of =itric oxide and endothelin to be covered in C)' ,,,
."A
E. 2-EM-!I,ICS -,) 2-EM-!+P+IE!IC <-C!+1S4 5,61.
Agents used in therapy of iron deficiency anaemia and megaloblastic anaemiaB
Erythropoietin,
5<-C'D (nO-*
Management of anaemia
<. ,E01+PS3C2I-!1IC P2-1M-C+/+G3 I,C/0)I,G
I,</-MM-!+,E P-I, A S0BS!-,CE -B0SE (=O-/ U 3*
5eneral Considerations (nO-*
'edative-7ypnotics (nO3*
sychopharmacology; AntianxietyB AntipsychoticsB Antidepressants (nO&*
Antiepileptics (nO3*
Therapy of neurodegenerative disorders;
Anti-arkinsonian agentsB cerebral vasodilators4nootropics (nO-*
:ocal anaesthetics (nO-*
Analgesics; 9pioidsB ='A$"s (nO&*
%harmacotherapy of pain including migraine
%harmacotherapy of rheumatoid arthritis and gout
'ubstance abuse; <anagement of opioid, alcohol and tobacco addictions (nO-*
G. MISCE//-,E+0S !+PICS 7 I4 5,68 H 2.
Autocoids 1to be covered before pain lectures2 (nO-*
Antiallergics; Antihistaminics (nO-*
"rugs used for bronchial asthma (nO-*
%harmacotherapy of cough
"rugs acting on immune system;
$mmunostimulants, immunosuppressantsB pharmacology of vaccines + sera (nO-*
"rugs acting on the uterus (nO-*
2.C2EM+!2E1-P3 I,C/0)I,G C-,CE1 C2EM+!2E1-P345,622 H 2.
5eneral considerations (nO-*
Antimicrobial agents; (nO6*
'ulphonamides + Cotrimoxa>ole
Huinoline derivatives
enicillins, Cephalosporins + 9ther W :actams
Aminoglycosides
<acrolides
Tetracyclines + Chloramphenicol
Phar"acothera&y of 0!I
5eneral principles of Antimicrobial use (nO-*
Antimycobacterial therapy; Anti-Aochs agentsB Anti-leprotic agents (nO&*
%harmacotherapy of tuberculosis
Antiproto>oal agents;
Antiamoebic, Antimalarials and Anti Aala a>ar (nO&*
harmacotherapy of malaria
-ntihel"inthics 5n61.
(against intestinal 4ematodes and &estodesA e0tra intestinal 4ematodes and
Trematodes)
-ntifungal agents 5n61.
-ntiviral agents including antiretroviral agents 5n62.
Phar"acothera&y of S!)s 5n61.
Princi&les of cancer che"othera&y and their adverse drug reactions 5n61.
1individual agents and regimes need not be taught2
I. E,)+C1I,+/+G34 5,612 H 2.
Introduction to endocrinology
1including 0ypothalamic and "nterior %ituitary hormones2 (nO-*
'teroids (nO3*
+lucocorticoids: 3se and Misuse
9estrogens + antagonists (nO-*
rogestins + antagonists (nO-*
9ral contraceptives + profertility agents (nO-*
Testosterone + anabolic steroids (nO-*
,ertility control
Thyroxine and antithyroid agents (nO3*
Agents affecting calcification (nO-*
Antidiabetic agents; $nsulinB 9ral antidiabetic drugs (nO3*
%harmacotherapy of iabetes Mellitus
=. -GE,!S 0SE) I, G-S!1+I,!ES!I,-/ )IS+1)E1S4 5,62.
harmacotherapy of nausea + vomiting (nO-*
harmacotherapy of peptic ulcer (nO-*
Management of dyspepsia
Management of diarrhoea and constipation
A* E%$9E%AT$)E <A=A5E<E=T; to be covered as a case stud%
reanaesthetic medication
reparation of surgical site; antiseptics etc.
:ocal Anaesthetics
'keletal muscle relaxants
"rugs used in post-operative period; analgesics, antiemetics etc.
/. MISCE//-,E+0S !+PICS I II 5,6#7:.
"rug-"rug $nteractions (nO-*
"rug use at extremes of age, in pregnancy + in organ dysfunction (nO3*
#se of chelating agents in heavy metal poisoningsB Environmental + occupational
toxicants and principles of management (particularly cyanide and C9* (nO-*
9cular pharmacology (nO-*
"ermatopharmacology (nO-*
General -naestheticsJ)F
%harmacotherapy of glaucoma and con&unctivitis
M. 1-!I+,-/ P2-1M-C+!2E1-P34 5,6(.
rescription writing and -drug concept
%ational "rug #seB Essential "rug :ist (E":*
Criticis" $ith reference to <iCed )rug Co"binations 5<)Cs.
#se and misuse of commonly used preparations; vitamins, antioxidants, en>ymes etc.
d. Termwise distribution
$ term
$ntroduction
5eneral pharmacology
Autonomic pharmacology
)rugs acting on cardiovascular syste" including drugs affecting coagulation and
those acting on the %idneys
$$ term
rescription writing and -drug concept
%ational use of drugsB Essential drug list
,euro7&sychiatric &har"acology including infla""ationE &ain and substance
abuse
Miscellaneous to&ics 7 I
Che"othera&y
Endocrinology
$$$ term
-gents used in gastro7intestinal disorders
eri operative management
Miscellaneous to&ics
Criticis" $ith reference to <)Cs
#se and misuse of commonly used preparations; vitamins, antioxidants, en>ymes etc.
e. !racticals" Total hours# number & contents
Total hours: -3.
4umber: -0
#ontents:
I ter" &racticals 5,6:.
$ntroduction to ractical harmacology, rescription Griting, harmacokinetics $,
%outes of Administration; 9ral, %outes of Administration; Topical, %outes of
Administration; arenteral, harmacokinetics $$; Applied harmacokinetics
II ter" &racticals 5,6:.
harmacodynamics $ ($solated Tissue, Cat =< !unction*, harmacodynamics $$
("og; 2 and %espiration*, 'creening TechniCues for =ew "rugs, Adverse "rug
%eactions, %ational harmacotherapy $, %ational harmacotherapy $$, 'ources of
"rug $nformation including scrutiny of romotional :iterature
III ter" &racticals 5,6(.
Case 'tudy -, Case 'tudy 3
%evision racticals (nO3*
f. .ooks recommended 4
-. 2asic + Clinical harmacology. Aat>ung 25 (Ed*, ublisher; rentice 7all
$nternational :td., :ondon.
3. harmacology + harmacotherapeutics. 'atoskar %', 2handarkar '" (Ed*,
ublisher; opular rakashan, 2ombay.
&. Essentials of <edical harmacology. Tripathi A" (Ed*, Faypee 2rothers,
publisher;<edical ublishers (* :td.
8. Clinical harmacology. :aurence "%, 2ennet =, 2rown <F (Ed*. ublisher;
Churchill :ivingstone
/eference books 4
3. 5oodman + 5ilmanEs The harmacological 2asis of Therapeutics. 7ardman
F5 + :imbird :E (Ed*, ublisher; <c5raw-7ill, =ew Kork.
&. A Textbook of Clinical harmacology. %oger 7F, 'pector %5, Trounce F%
(Ed*, ublisher; 7odder and 'toughton ublishers.
#. Evaluation
c.-ethods
Theory, ractical + viva
b. !attern of Theor% ,0amination including 1istribution of -arks# 2uestions &
Time
,ature of ?uestion Pa&er
3acult% with +ear " S,&(41 -..S
Sub5ect " P2-1M-C+/+G3 A !2E1-PE0!ICS
!a$er " I
Total -arks " 67 Time " 8 'ours
Section @-@ 5; Mar%s.
Instructions47
-* Dill (dark* the appropriate empty circle below the Cuestion number once only..
3* #se blue9blac% ball point pen only.
&* Each Cuestion carries one 9 half "ar%.
(. Students $ill not be allotted "ar% if he9she over$rites stri%es or &ut $hite in% on the cross
once "ar%ed.
/* "o not write anything on the blank portion of the Cuestion paper. $f written anything, such type of
act will be considered as an attempt to resort to unfair means.
Section @-@ 4 MC? 5; "ar%s.
Huestion =o. Huestion "escription "ivision of <arks Total <arks
-. Total <CHs ; -? -? I J .0
Section @B@ A @C@ 52 Mar%s.
Instructions47
-* All Cuestions are compulsory.
3* The number to the right indicates full marks.
&* "raw diagrams wherever necessary.
(. -ns$er each section in the res&ective ans$erboo% only. -ns$ers $ritten in the ina&&ro&riate
sectional ans$er boo%s $ill not be assessed in any case.
/* "o not write anything on the blank portion of the Cuestion paper. $f written anything, such type of act
will be considered as an attempt to resort to unfair means.
Section @B@ 4 B-? 52' Mar%s.
Huestion =o. Huestion "escription "ivision of <arks Total <arks
3. Brief ans$er Buestions
5-tte"&t any five out of siC.
a* b* c* d* e* f*
/ I 8 3.
Section @C@ 4 /-? 512 Mar%s.
Huestion =o. Huestion "escription "ivision of
<arks
Total <arks
&. -tte"&t any t$o out of three4
Long answer question onl%
a* b* c*
3 I ? -3
3acult% with +ear " S,&(41 -..S
Sub5ect " P2-1M-C+/+G3 A !2E1-PE0!ICS
!a$er " II
Total -arks " 67 Time " 8 'ours
Section @-@ 5; Mar%s.
Instructions47
-* Dill (dark* the appropriate empty circle below the Cuestion number once only..
3* #se blue9blac% ball point pen only.
&* Each Cuestion carries one 9 half "ar%.
(. Students $ill not be allotted "ar% if he9she over$rites stri%es or &ut $hite in% on the cross
once "ar%ed.
/* "o not write anything on the blank portion of the Cuestion paper. $f written anything, such type of
act will be considered as an attempt to resort to unfair means.
Section @-@ 4 MC? 5; "ar%s.
Huestion =o. Huestion "escription "ivision of <arks Total <arks
-. Total <CHs ; -? -? I J .0
Section @B@ A @C@ 52 Mar%s.
Instructions47
-* All Cuestions are compulsory.
3* The number to the right indicates full marks.
&* "raw diagrams wherever necessary.
(. -ns$er each section in the res&ective ans$erboo% only. -ns$ers $ritten in the ina&&ro&riate
sectional ans$er boo%s $ill not be assessed in any case.
/* "o not write anything on the blank portion of the Cuestion paper. $f written anything, such type of act
will be considered as an attempt to resort to unfair means.
Section @B@ 4 B-? 52' Mar%s.
Huestion =o. Huestion "escription "ivision of <arks Total <arks
3. Brief ans$er Buestions
5-tte"&t any five out of siC.
a* b* c* d* e* f*
/ I 8 3.
Section @C@ 4 /-? 512 Mar%s.
Huestion =o. Huestion "escription "ivision of <arks Total <arks
&. -tte"&t any t$o out of three4
Long answer question onl%
a* b* c*
3 I ? -3
c. To$ic distribution
A* P2-1M-C+/+G3 P-PE1 I includes 5eneral harmacology including drug-
drug interactionsB Autonomic =ervous 'ystem, Cardiovascular 'ystem including
drugs affecting Coagulation and those acting on the AidneysB 7aematinicsB Agents
used in 5astro-$ntestinal "isordersB 9cular pharmacologyB "rug use at extremes
of age, in pregnancy + in organ dysfunctionB "iagnostic + Chelating agentsB
Environmental + 9ccupational ollutantsB )itamins
2* P2-1M-C+/+G3 P-PE1 II includes =euro-sychiatric harmacology
including Antiinflammatory-Analgesics and Addiction + its managementB
harmacology in 'urgery (particularly peri-operative management*B
Chemotherapy including Cancer ChemotherapyB EndocrinologyB "ermatologyB
<iscellaneous Topics $ (:ipid-derived autacoidsB =itric 9xideB Allergy -
7istaminics + Antihistaminics including anti-vertigoB Anti AsthmaticsB Anti-
tussive agentsB $mmunomodulatorsB )accines + seraB "rugs acting on the uterus*
d. -arking scheme
Each paper of 8. marks as shown in the above table.
e. 4ature of $racticals and duration
Practical 2eads Mar%s 28
Prescri&tion $riting #
:ong (&*
'hort (3*
Criticis" ;
rescription + rewriting (8*
Dixed dose formulation (8*
Clinical harmacy
/
5dosage for"sE routes of ad"inistrationE label infor"ation and instructions.
i. S&ots ;
a Experimental harmacology N 5raphs, <odels for evaluation, $dentification of a
drug, $nterpretation of data (3*
b 7uman harmacodynamics - "rug $dentification N urine analysis, eye chart, -
'ub!ective 4 ob!ective effects of a drug (3*
c Therapeutic problems based on pharmaceutical factors - 9utdated tablet,
2ioavailability, "osage form, Ethics and 'ources of drug information (3*
d %ecognition of A"%s + interaction of commonly used drugs (3*
Dor each of the 8 groups (a, b, c + d* 3 spot Cuestions each of -mark to be asked.
Time distribution;
Dor prescription and criticism the time given will be J hour.
Dor clinical pharmacy practical viva will be taken on pre-formed preparations and4or
marketed formulations. The students may be asked to write labels and instructions to
be given to the patients or demonstrate how specific dosage forms are administered
and state the precautions to be taken4 explained to the patients while using them. The
time for this will be / min.
Dor spots 3. min will be given (3 min per spot*.
Thus the total time for the practical examination will be - hour.
f. 9i:a" duration and to$ic distribution
)iva -8 marks
"uration -. mins
Dour examiners / mins with each candidate
Two examiners for topics of paper $ - systems to be distributed
Two examiners for topics of paper $$ - systems to be distributed
At each table marks will be given out of 6.
g. !lan for internal assessment
The time-table for internal assessment will be as follows;
<or the batches $hich have joined before =une 2''1
$ term
-
st
midterm; After ?. teaching days (<CHs, and 'AHs*
-
st
term ending; After -3. teaching days (Theory and harmacy racticals*
$$ term
3
nd
midterm; After ?. days of 3
nd
term (<CHs and 'AHs*
3
nd
term ending; At the end of 3
nd
term (Theory and racticals; Exptal4Clinical
harmacy*
$$$rd term
relims examination on the basis of #niversity pattern -Theory, racticals and )iva
1Minimum 5 weeks gap mandatory between %reliminary and 3niversity
e*aminations2
Dor each mid-term examination 8. <CHs (each worth -43 mark* will be administered
to the students along with / 'AHs (each of 3 marks with an option of / out of ?*. The
total time will be - hour and the total marks will be &..
The term ending examination will be of 0. marks and the nature of Cuestions will be
as per #niversity exam.
This will be followed by practical (total time -J hours*.
To familiari>e the students with the Xviva-vocYE, the marks for the practical may be
kept at only 3., while 3. marks be reserved for viva on theory topics (total 8. marks*.
<or the batches joining in =une 2''1 and later
$ term
-
st
term ending; After -3. teaching days (Theory and harmacy racticals*
$$ term
3
nd
term ending; At the end of the 3
nd
term (Theory and racticals; Exptal4Clinical
harmacy*
$$$rd term
relims examination on the basis of #niversity pattern -Theory, racticals and )iva
1Minimum 5 weeks gap mandatory between %reliminary and 3niversity
e*aminations2
Dor the terminal theory examination students will be evaluated by a combination of 30
<CHs (each worth -43 mark*, -. 'AHs (each of 3 marks with an option of -. out of
-3* and 3 :AHs (option of 3 out of & each worth 0 marks*. The total time allotted for
this /. marks paper will be 3hours &.minutes.
This will be followed by practicals (total time -J hours*.
To familiari>e the students with the Xviva-vocYE, the marks for the practical may be
kept at only 3., while 3. marks be reserved for viva on theory topics (total 8. marks*.
relim pattern will be as per the #niversity exam with 3 papers in theory, each of 3
hours duration.
-------------------------------------------------------------------------------------------------------
<+1E,SIC ME)ICI,E -,) ME)IC-/ =01ISP10)E,CE
I,C/0)I,G !+KIC+/+G3
1. Goal
The broad goal of teaching undergraduate students Dorensic <edicine is to produce a
physician who is well informed about <edico-legal responsibility during his4her
practice of <edicine. 7e4'he will also be capable of making observations and
inferring conclusions by logical deductions to set enCuiries on the right track in
criminal matters and associated medico-legal problems. 7e4'he acCuires knowledge
of law in relation to <edical practice, <edical negligence and respect for codes of
<edical ethics.
2. Educational objectives
(a) Knowledge
At the end of the course, the student shall be able to
i. identify the basic <edico-legal aspects of hospital and general practice
ii. define the <edico-legal responsibilities of a general physician while rendering
community service either in a rural primary health centre or an urban health centre
iii. appreciate the physicianEs responsibilities in criminal matters and respect for the
codes of <edical ethics
iv. diagnose, manage and identify also legal aspect of common acute and chronic
poisonings
v. describe the <edico-legal aspects and findings of post-mortem examination in
cases of death due to common unnatural conditions and poisonings
vi. detect occupational and environmental poisoning, prevention and epidemiology of
common poisoning and their legal aspects particularly pertaining to GorkmenEs
Compensation Act
vii. describe the general principles of analytical toxicology
(b) Skills
- co"&rehensive list of s%ills and attitude reco""ended by Medical
Council of India 1egulationE 1GG: desirable for Bachelor of Medicine and
Bachelor of Surgery 5MBBS. Graduate for <orensic Medicine and
!oCicology
At the end of the course, the student shall be able to
i. make observations and logical inferences in order to initiate enCuiries in criminal
matters and <edico-legal problems
a. to be able to carr% on $ro$er -edicolegal e0amination and
documentationB/e$orting of In5ur% and )ge
b. to be able to conduct e0amination for se0ual offences and into0ication
c. to be able to $reser:e rele:ant ancillar% materials for medico legal
e0amination
d. to be able to identif% im$ortant $ostmortem findings in common unnatural
deaths
ii. diagnose and treat common emergencies in poisoning and chronic toxicity
iii. make observations and interpret findings at post-mortem examination
iv. observe the principles of medical ethics in the practice of his profession
(c) Integration
"epartment shall provide an integrated approach towards allied disciplines like
athology, %adiology, Dorensic 'ciences, 7ospital Administration etc. to impart
training regarding <edico-legal responsibilities of physicians at all levels of health
care. $ntegration with relevant disciplines will provide scientific basis of clinical
toxicology e.g. <edicine, harmacology etc.
. !otal duration of Para7clinical teaching & 'emesters
Total &?. teaching days
!otal nu"ber of teaching hours allotted for <orensic
Medicine A !oCicology -.. hours
(. Syllabus
a. Learning methods
:ectures, tutorials, practical demonstrations
"istribution of teaching hours
"idactic lectures should not exceed one third of the time schedule, two third schedule
should include PracticalsE )e"onstrationsE Grou& discussionsE Se"inars and
!utorials.
:earning process should include living experiences and other case studies to initiate
enCuiries in criminal matters and <edico-legal problems.
A* Theory (lectures + ,.. 8.
Tutorials, seminar + allied* ,.. 3.
Total ,.. ?.
B. Practicals 5including de"onstrations. ,.. 3/
,.. -/
Total .,. 8.
This period of training is minimum suggested. Ad!ustments whenever reCuired,
depending on availability of time, be made.
b. & c. Sequential organisation of contents & their di:ision
!o&ic $ise distribution
The course is designed to meet the needs of a 5eneral ractitioner and includes the
following topics;
-. Dorensic <edicine 8. 7rs
3. Toxicology 3. 7rs
&. <edical Furisprudence -3 7rs
8. :egal rocedures in <edico-:egal cases .0 7rs
/. Court attendance when medical
evidence is being recorded .8 7rs
?. $ntegrated approach towards
allied disciplines .? 7rs
6. Tutorial and 'eminars -. 7rs
!otal4 1'' 2rs
Part I 1 <orensic Medicine; (=O8.*
Contents A division
=ote; <ust Anow (<A*, )esirable to Fno$ 5)F. and LMN is ,ice to Fno$ 5,F.
-. )E<I,I!I+,E SC+PE 1E/E*-,! !+ S0B=EC!
-. 7istory of Dorensic <edicine
2. ,eedE Sco&eE I"&ortance and &robative value of Medical evidence in Cri"e
Investigation
B. PE1S+,-/ I)E,!I!3 ,EE) -,) I!S IMP+1!-,CE.
1. )ata useful for Identification of /iving and )ead
2. -ge esti"ation and its "edico7legal I"&ortance
&. 'ex determination and itEs medico-legal importance
8. 9ther methods of establishing identity; Corpus "elicti, )actylogra&hyE !attoo
"ar%s, "eformities, 'cars and other relevant factors
/. $dentification of decomposed, <utilated bodies and skeletal remains
?. <edico legal aspect of P"=A fingerprinting - a brief introduction
:. Medico 7 legal as&ect of blood and blood stains
CollectionE Preservation and )is&atch of S&eci"en for Blood and other ancillary
"aterial for identification and Medico7legal eCa"ination
C* MEC2-,IC-/ I,=01IES -,) B01,S
1. )efinition and classification of injuries4 -brasionsE ContusionsE /acerationsE
Incised and Stab injuryE <irear" and EC&losion injuryE <abricated and
)efence injury
2. Medico7legal as&ect of injury9hurtE si"&le and grievous hurtsE "urderE -nte
7"orte"E Post"orte" >oundsE -ge of the injuryE cause of death and
relevant sections of I.P.C.E Cr.P.C.
. Causative >ea&on and a&&earance of SuicidalE -ccidental and 2o"icidal
injuries
8. hysical methods of Torture and their identification
#. 1e&orting on Medico7legal cases of 2urts
?. 1egional injuries; 7ead in!ury, cut throat in!uries and %oad traffic accident
in!uries
6. !her"al injuries; $n!uries due to heat and cold, Drostbite, 2urns, 'calds and
2ride burning
0. $n!uries due to Electricity, :ightening
CollectionE Preservation and )is&atch of S&eci"en for Blood and other ancillary
"aterial for Medico7legal eCa"ination
). ME)IC+7/EG-/ -SPEC!S +< SEKE M-11I-GE -,) I,<-,!
)E-!2
-. SeCual +ffences and &erversions; =atural (1a&e, Adultery, and $ncest*,
#nnatural (Sodo"yE Bestiality and 2uccal coitus* :esbianism, perversions and
relevant sections of I.P.C. and Cr.P.C.
3. Dertility, I"&otence, 'terility, *irginity, and =ullity of marriage and divorce on
<edical ground
&. PregnancyE )elivery, aternity, :egitimacy, Artificial $nsemination,
PDertilisation in )itro, P'terili>ation (Damily lanning <easures*
8. -bortionsE Medical !er"ination of &regnancyE cri"inal abortions, 2attered
2aby 'yndrome, Cot deaths and relevant sections of $..C. and Cr..C., M.!.P.
-ct of 1G:1 and foetal seC deter"ination -ct
/. Infant death 5Infanticide.
i. "efinition Causes, <anners and Autopsy features
ii. )eter"ination of age of <oetus and Infant
iii. Signs of live7bornE stillborn and dead born child
CollectionE Preservation and )is&atch of S&eci"en4 2airE se"inal fluid9 stains
and other ancillary "aterial for "edico7legal eCa"inationE eCa"ination of
se"inal stains and vaginal s$abs
E. ME)IC+7/EG-/ -SPEC!S +< )E-!2
1. )efinition and conce&t of deathE stagesE "odesE Signs of death and its
i"&ortance
3. Changes after death, Cooling, 7ypostasis, Changes in eye, <uscle changes,
utrefaction, 'aponification, <ummification, Esti"ation of ti"e since death
&. )eath Certification, roximate causes of death, causes of sudden deaths, =atural
deaths. resumption of death and survivorship, disposal and preservation of dead
8. $ntroduction to PThe Anatomy Act, PThe 7uman organ transplantation Act. -118
/. <edico-legal aspects and findings of post-mortem examination in cases of death
due to co""on unnatural conditions
?. Sudden uneC&ected death, deaths from starvation, cold and heat and their
medico-legal importance
6. Medico7legal as&ects of death fro" -s&hyCiaE 2angingE StrangulationE
'uffocation and )ro$ning
<. ME)IC+7/EG-/ -0!+PS3
1. -uto&sy4 +bjectivesE <acilitiesE 1ules and Basic techniBuesE Profor"a for
re&orting "edico7legal auto&sy
3. EChu"ation, examination of mutilated remains, 9bscure autopsy and &ost7
"orte" artifacts
CollectionE &reservation and des&atch of "aterial for various investigations to
<orensic Science /aboratory
G. M<+1E,SIC PS3C2I-!13
-. )efinitionE General ter"inology and P 2asic concept of normality and
abnormality of human behaviour, Civil and Criminal responsibility
3. Examination, Certification, restraint and admission to <ental 7ospital
&. <ental 7ealth Act N rinciples and 9b!ectives
Part I 2 !oCicology; (=O3.*
-. P+IS+,S -,) !2EI1 ME)IC+7/EG-/ -SPEC!S
-. )efinition of &oisonE General consideration and /a$s in relation to
&oisonsZ=arcotic drugs and psychotropic substances Act, P'chedules 7 and :
drugs, Pharmacy Act, )uties and res&onsibilities of attending &hysician
3. Co""on &oisons and their classificationE Identification of co""on &oisons,
%outes of administration, Actions of poisons and factors modifying them,
)iagnosis of &oisoning 5Clinical and Confir"atory. E !reat"ent9
Manage"ent of cases of acute and chronic &oisonings
&. Addiction and 7abit forming drugs, drug dependence
(. +ccu&ational and environ"ental &oisoningE &revention and E&ide"iology of
co""on &oisoning and their legal as&ects &articularly &ertaining to
>or%"enNs Co"&ensation -ct
#. Medico7/egal as&ects and findings of &ost"orte" eCa"ination in cases of
death due to &oisonings
B. P+IS+,S !+ BE S!0)IE)
-. Corrosive4 Eu&horic -cid, =itric Acid, 7ydrochloric Acid, Carbolic -cid and
9xalic Acid, Sodiu" and Potassiu" and -""oniu" 2ydro7+Cide
3. ,on7"etallicE Metallic Poisons and Industrial haOards4 Phos&horus and
compounds of :ead, Arsenic, <ercury, Co&&er, and 5lass powder
&. Plant Poisons4 CastorE Croton, Capsicum, 'emicarpus Anacardium (2hilawa*,
Calatropis 5igantea, -brus Precatorius 51atti.E )haturaE Cannabis IndicaE
CocaineE +&iu", Aconite, Kellow 9leander, Strychnine
8. -ni"al and Bacterial Poisons4 Sna%es, 'corpion and Dood poisoning
/. -lcohol 5)run%enness. Ethyl -lcoholE Methyl -lcohol, Aerosene, 2arbiturates
?. -s&hyCiant A Gaseous Poisons4 Carbon MonoCide, Gar gases, 7ydrocyanic
acid, and Cyanides
:. InsecticidesE &esticides and Miscellaneous &oisons4 +rgano7Phos&horus
Co"&oundsE +rgano7Chloro Co"&oundsE Carba"ates 5Carbaryl. and
1odenticides 5Phos&hides.
CollectionE Preservation and for$arding of evidenceE re"ains of &oisonE body
discharges and viscera etc. to <orensic Science /aboratory in cases of &oisoning
C. <+1E,SIC SCIE,CE /-B+1-!+134 5B1IE<.
1. -i"sE objectsE general %no$ledge about <orensic Science /aboratory
2. General &rinci&les of analytical toCicology
Part I Medical =uris&rudence; (=O-3*
-. /EG-/ -,) E!2IC-/ -SPEC!S +< P1-C!ICE +< ME)ICI,E
-. The Indian Medical Council, the Act, Dormation and DunctionsB
State Medical Council; Dormation, Dunctions, and %egistration
3. 1ights and obligations of 1egistered Medical Practitioners and &atientE )uties
of &hysicians and &atients, Euthanasia
. Infa"ous conductE Professional secrecy and &rivileged co""unications
8. Codes of Medical EthicsE "edical etiBuetteE Medical ,egligence and
contributory negligence, Precautionary "easures and defences for Medical
Practitioners against legal actionsE Medical9)octors inde"nity insuranceE
Consu"er Protection -ct relevant to "edical &ractice
/. <edical Ethics and prohibition of Torture + care of Torture )ictims
B. )E<I,I!I+, +< 2E-/!2 -,) I!EMS !+ CE1!I<3 -B+0! 2E-/!2
1. Co""on "edico7legal &roble"s in 2os&ital &racticeE Consent in Medical
ECa"ination and treat"entE under treat"ent9 Sic%ness and <itness
certificateE "aintenance of "edical records
3. 'ocial, <edical, :egal and Ethical problems in relation to A$"'
C. -C!S -,) SC2EMES 1E/-!E) !+ ME)IC-/ P1+<ESSI+, I,
B1IE<4
>or%"enNs co"&ensation -ct, P <ental 7ealth Act, Medical Practitioner -ctE
rotection of human rights Act, -11&, P =ational 7uman %ights Commission, P
7uman 9rgan Transplantation Act and other relevant sections of $..C., Cr..C. and
$.E. Act. <aharashtra civil medical code, 7ospital administration manual
Part I ( /egal &rocedures in "edico7legal cases; (=O0*
A. Medico7/egal Investigations of death in suspicious circumstances, different
InBuest, type of offences
2. !y&es of Cri"inal courts and their &o$ers, punishments prescribed by law,
%inds of $itnessesE EvidenceE )ocu"entary Medical evidence, "ying
declaration and "ying deposition
C. The Trial of criminal cases, 1ules and Conventions to be follo$ed by
Medical >itness at Medical evidence, sub&oenaE conduct "oney
). 1elevant Sections fro" the Indian Evidence -ctE Indian Penal code and
Cri"inal Procedure code
,+!E 4 Must %no$, desirable to know and X P X is nice to know
d. Termwise distribution
[[[[[[
!er"s /ectures ,on I /ectures Pracs. )e"os.
!uts9Se"9-llied
I !er" 1# P '; '8 '8
II !er" 1# P 1' '# '8
III !er" 1' P ': '( ';
77777777777777777777777777777777777777777777777777777777777777777777777777777777777777
!otal (' P 2# 1# 2'
This period of training is the minimum suggested. "d&ustments whenever re6uired,
depending on availability of time, be made
e. !racticals (including demonstrations) " Total no.of hours & contents
racticals will be conducted in the laboratories.
9b!ective will be to assess proficiency in skills, conduct of experiment, interpretation
of data and logical conclusion.
Emphasis should be on candidateEs capacity in making observations and logical
inferences in order to initiate enCuiries in criminal matters and medico-legal
problems.
Total <arks; 3/ T -/ O 8.
Contents;
Part 1 <orensic Medicine
1e&ort on4
1. Esti"ation9Certification of -ge
2. 1ecording of finger&rints
. ECa"ination9Certification of the Injured
QPrescribed <or"sR
(. ECa"ination of the Causative -gents in cases of Injuries
5e.g. >ea&onsE Instru"ents.
a. 2ard and blunt $ea&ons
b. Shar& cuttingE shar& &ointed and Shar& 2eavy cutting $ea&ons
c. <irear" $ea&ons
#. SeCual offences 4
a. ECa"ination9Certification of *icti"
b. ECa"ination9Certification of -ccused
8. ECa"ination of <oetus to o&ine about age
:. ECa"ination of Bones and teeth for Medico7legal &ur&ose to deter"ine
ageE seCE statureE cause of deathE ti"e since death
a. S%ull and Mandible
b. Sca&ulaE Sternu" and 0&&er li"b bones
c. Sacru" and hi& bone9 Pelvic bone
d. /o$er li"b bones
Study of4
;. Medical certification of cause of )eath as &er Birth and )eath
registration -ct QPrescribed <or"sR
1. Studies of S%iagra"s for estimation of age, bony in!ury, foreign body, and
pregnancy
-.. Photogra&h of different events of Medico7legal i"&ortance and post-
mortem changes
--. Study of *arious "useu" s&eci"ens of medico-legal significance
-3. Study of *arious slides of medico-legal significance
1. )e"onstration of Instru"ents4
a. #sed in treatment of acute poisoning cases
b. #sed for causing abortions
c. #sed for carrying out autopsy
QStandard hu"an auto&sy dissection BoC9setR
Part 2 <orensic !oCicology
1. ECa"ination9Certification of -lcoholic QPrescribed <or"s S-N
ASBNR
2. Study of Co""on &oisons4
QSul&huric -cid, =itric Acid, 7ydrochloric AcidE Carbolic -cid and +Calic
-cidE 'odium and otassium 7ydro-9xide, Phos&horousE :ead, Arsenic,
<ercuryE Co&&erE Glass &o$derE CastorE CrotonE Capsicum, 'emicarpus
Anacardium (2hilawa*, Calatropis 5igantea, -brus Precatorius 51atti.E
)haturaE Cannabis IndicaE +&iu"E Aconite, Kellow 9leander, 'trychnine,
Sna%esE Scor&ionE -lcoholE Methyl -lcoholE FeroseneE 2arbituratesE +rgano7
&hos&horus co"&oundsE +rgano Chloro co"&oundsE Carba"ates
5Carbaryl.R and other co""only used &oisonsE antidotes and &reservatives
Part Medical =uris&rudence
Study of Medical Certificates QPrescribed <or"sR
a. Sic%ness Certificate
b. <itness Certificate
c. Certificate of Physical fitness
d. M Medical certificate &rescribed under Mental 2ealth -ct 4 1G;:
e. M Medical Certificate of Sound9 0nsoundness of "ind.
Part I ( /egal &rocedures in "edico7legal cases
Study of the various &rescribed <or"s;
Consent to surgery -naesthesia and other Medical servicesE %eCuest for
sterili>ation, Consent to access to hospital records, Authori>ation for Autopsy,
)ead body Challan used for sending a dead body for &ost7"orte"
eCa"inationE %eCuest for the second inCuest by <agistrate on the dead bodyE
Provisional &ost7"orte" certificateE Post7"orte" for"E Pictorial Post7
"orte" for"E <or" for the <inal cause of deathE Dorms for despatch of
exhibits other than the viscera to chemical analyser, Dorms for despatch of )iscera
for 7istopathological Examination, <or" for dis&atch of viscera to che"ical
analyserE Dorensic 'cience :aboratory report form, 'ummons to witness.
Each student shall attend and record as a clerk
a. As many as possible cases 4 items of medico-legal importance
b. -. cases of medico-legal autopsies
2oth above XaE and XbE should be recorded in the approved roforma in the single
Fournal. The Fournal should be scrutinised by the teacher concerned and presented for
the inspection and evaluation during the university examination.
Each student shall attend the court at least 3 cases when <edical Evidence is being
recorded.
f. .ooks recommended
1. ModiNs !eCtboo% of Medical =uris&rudence and !oCicology
Ed. 22E 1GGGE by B.*. Subra"anya"E Butter$orth
3. The Essentials of Dorensic <edicine + Toxicology by A.'. =arayan %eddy
&. arikhEs Textbook of <edical Furisprudence and Toxicology.
(. !eCt Boo% of <orensic Medicine I =.B. Mu%herjii *+/ 1 A 2
#. Princi&les of <orensic Medicine 7 -. ,andy
?. Toxicology at a 5lance by "r '.A. 'inghal
6. 2ernard Anight et. All; CoxEs <edical Furisprudence + Toxicology
/eference books
-. %ussell '. Disher + Charles '.etty; Dorensic athology
3. Aeith 'impson; Dorensic <edicine
&. Furgen :udwig; Current <ethods of autopsy practice.
8. 5radwohl N :egal <edicine
/. A "octors 5uide to Court N 'impson
?. olson C.F. ; The essentials of Dorensic <edicine
6. Adelson, :.; The athology of 7omicide.
0. Atlas of :egal <edicine (Tomro Gatonbe*
1. 'pti>, G.#. + Disher, %.'.; <edico-legal $nvestigation of "eath.
-.. A 7and 2ook of :egal athology ("irector of ublicity*
--. TaylorEs rinciples + ractice of <edical Furisprudence.
Edited by A.Aeith <ant, Churchill :ivingstone.
-3. %atanlal + "hira!lal, The $ndian enal CodeB Fustice 7idayatullah + ).%.
<anohar
-&. %atanlal + "hira!lal, The Code of Criminal procedureB Fustice 7idayatullah
+ '.. 'athe
-8. %atanlal + "hira!lal, The :aw of EvidenceB Fustice 7idayatullah + ).%.
<anohar
-/. <edical :aw + Ethic in $ndia N 7.'. <ehta
-?. 2ernard Anight ; Dorensic athology
-6. Code of medical ethics ; <edical Council of $ndia, approved by Central
5overnment, #4' && (m* of $<C Act, -1/? (9ct -16.*
-0. Arogman, G.<.; The human skeleton in legal medicine.
-1. DE Camps, F< Cameren, "avid :anham ; ractical Dorensic <edicine
3.. ).). illay ; <odern <edical Toxicology.
#. Evaluation
a. -ethods
Theory, ractical + viva
b. !attern of Theor% ,0amination including 1istribution of -arks# 2uestions#
Time
,ature of ?uestion Pa&er
3acult% with +ear " S,&(41 -..S
Sub5ect " <+1E,SIC ME)ICI,E A !+KIC+/+G3
!a$er "
Total -arks " 67 Time " 8 'ours
Section @-@ 5; Mar%s.
Instructions47
-* Dill (dark* the appropriate empty circle below the Cuestion number once only..
3* #se blue9blac% ball point pen only.
&* Each Cuestion carries one 9 half "ar%.
(. Students $ill not be allotted "ar% if he9she over$rites stri%es or &ut $hite in% on the cross
once "ar%ed.
/* "o not write anything on the blank portion of the Cuestion paper. $f written anything, such type of
act will be considered as an attempt to resort to unfair means.
Section @-@ 4 MC? 5; "ar%s.
Huestion =o. Huestion "escription "ivision of <arks Total <arks
-. Total <CHs ; -? -? I J .0
Section @B@ A @C@ 52 Mar%s.
Instructions47
-* All Cuestions are compulsory.
3* The number to the right indicates full marks.
&* "raw diagrams wherever necessary.
(. -ns$er each section in the res&ective ans$erboo% only. -ns$ers $ritten in the ina&&ro&riate
sectional ans$er boo%s $ill not be assessed in any case.
/* "o not write anything on the blank portion of the Cuestion paper. $f written anything, such type of act
will be considered as an attempt to resort to unfair means.
Section @B@ 4 B-? 52' Mar%s.
Huestion =o. Huestion "escription "ivision of <arks Total <arks
3. Brief ans$er Buestions
5-tte"&t any five out of siC.
a* b* c* d* e* f*
/ I 8 3.
Section @C@ 4 /-? 512 Mar%s.
Huestion =o. Huestion "escription "ivision of <arks Total <arks
&. -tte"&t any t$o out of three4
Long answer question onl%
a* b* c*
3 I ? -3
c. To$ic distribution in the theor% $a$er
'ection A + C; Dorensic <edicine, Toxicology, <edical Furisprudence, :egal
rocedure
'ection 2; Dorensic <edicine, Toxicology and4or <edical Furisprudence
d. -arking scheme
As shown above
e. 4ature of $racticals and duration
!racticals -arks C7
%eport on; 'ix Exercises \Gith available resources] Time; About 3 hrs.
-. An $n!ured +1 Age of the child
+1 An Alcoholic +1 'exual offence .6 <arks
3. 2one +1 "etermination of age of Doetus ./ <arks
&. Geapon ./ <arks
8. Certificate of 'ickness, fitness +1 "eath. ./ <arks
/. %eport on TG9 oison .8 <arks
?. %eport on any TG9 articles; \'kiagram +1
hotographs +1 'lides +1 <useum
'pecimens +1 $nstruments] .8 <arks
----------------------
T9TA: ' Mar%s
$n respect of items - to ?, students will be expected to prepare their %eports as if they
would be reCuired to submit it to the investigating authority concerned within the time
allotted, and the examiners will be assessing proficiency in skills, conduct of
experiment, interpretation of data and logical conclusion. Emphasis should be on
candidateEs capacity in making observations and logical inferences in order to initiate
enCuiries in criminal matters and medico-legal problems.
f. 9i:a " duration and to$ic distribution
)iva-vocY; Time; About 3. <in
There will be TG9 tables examining each student separately on the topics XaE and XbE.
)iva -. marks
"uration 3. mins
Dour examiners -. mins with each candidate
Two examiners for topics a. Toxicology and <edical Furisprudence
Two examiners for topics b. Dorensic <edicine and :egal rocedures
At each table marks given will be out of / and then added together (total out of -.*
g. !lan for internal assessment
The time-table for internal assessment will be as follows;
S&',-, (3 I4T,/4)L )SS,SS-,4T DIT' 3/,2E,4&+ (3
,F)-I4)TI(4S 3(/ T', .)T&',S D'I&' ')9, G(I4,1 .,3(/,
GE4, 877;
<arks for internal assessment XAE shall be calculated on the basis of two mid
terminals + three terminal college examinations conducted. "uring mid terminal
(periodical examination* assessment should be done by <CHs of 'ingle 2est
%esponse type.
<arks for internal assessment X2E shall be calculated on the basis of three
terminal college examinations (6 marks* + day-to-day class practical work and
%ecord (& marks*.
"epartment will maintain a register for periodic evaluation of their students.
The internal assessment will be done separately for theory and practical examinations.
- total of # 5five. eCa"inations $ill be conducted as under4
<1E?0E,C3 -,) M-1FI,G +< EK-MI,-!I+, <+1 I,!E1,-/ -SSESSME,!
!er"$ise distribution !heory9Practical 5!otal Mar%s.
I !er"
9ne <idterm -/ 4 no practicals
-
st
Terminal 8. 4 3/
II !er"
9ne <idterm -/ 4 no practicals
3
nd
Terminal 8. 4 8.
III !er"
9ne term ending reliminary 8. 4 8.
S&',-, (3 I4T,/4)L )SS,SS-,4T DIT' 3/,2E,4&+ (3
,F)-I4)TI(4 3(/ T', .)T&',S G(I4I4* I4 GE4, 877; )41 L)T,/
I ter"
-
st
term ending; After -3. teaching days (Theory and racticals*
II ter"
3
nd
term ending; At the end of the 3
nd
term (Theory and racticals*
III ter"
relims examination on the basis of #niversity pattern -Theory, racticals and )iva
1Minimum 5 weeks gap mandatory between %reliminary and 3niversity
e*aminations2
Dor the terminal theory examination students will be evaluated by a combination of 30
<CHs (each worth -43 mark*, ? 'AHs (each of 3 marks with an option of ? out of 6*
and 3 :AHs (option of 3 out of & each worth 6 marks*. The total time allotted for this
8. marks paper will be 3 hours.
This will be followed by practicals (total time -J hours*. The marks for the $ term
practicals will be 3/ and for the $$ term will be 8..
To familiari>e the students with the Xviva-vocYE, for the $ term the marks for the
practicals may be kept as -/, while -. marks be reserved for viva on theory topics
(total 3/ marks*B for the $$ term the marks for the practicals may be kept as &., while
-. marks be reserved for viva on theory topics (total 8. marks*.
relim pattern will be as per the #niversity exam.

-------------------------------------------------------------------------------------------------------
1E*ISE) I,!E1,-/ -SSESSME,! EK-MI,-!I+, SC2EME $.e.f. =0,E 2'': EK-MI,-!I+,
3E-1 47 Second MBBS
S, Subject
1
st
!er" End 2
nd
!er" End Preli"inary ECa"ination
Se"ester !heory Practical Se"ester !heory Practical Se"ester !heory Practical
5-. 5B. 5C. 5). 5E. 5<.
-. harmacology $$$ /. 8. $) /. 8. ) 0. 8.
3. athology $$$ /. 8. $) /. 8. ) 0. 8.
&. <icrobiology $$$ /. 8. $) /. 8. ) 0. 8.
8. D<T $$$ 3. 3. $) 3. 3. ) 8. 8.
5B. Calculation Method47
$* Theory <arks to be send to the #niversity out of -/ Except D<T O
(A*T(C*T(E*
-3
O
/.T/.T0.
-3
O
-0.
-3
O -/
$$* ractical <arks to be send to the #niversity out of -/ Except D<T O
(2*T("*T(D*
0
O
8.T8.T8.
0
O
-3.
0
O -/
$$$* Dor D<T Theory <arks to be send to the #niversity out of -. O
(A*T(C*T(E*
0
O
3.T3.T8.
0
O
0.
0
O -.
$)* Dor D<T ractical <arks to be send to the #niversity out of -. O
(2*T("*T(D*
0
O
3.T3.T8.
0
O
0.
0
O -.

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