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B.
C.
D.
2.
Rhesus factor is an antigen present on the surface of red blood cells of Rhesus positive
individuals.
+
Rhesus positive (Rh ) is dominant to Rhesus negative (Rh ). A mother with Rhesus negative
blood gives birth to a baby with Rhesus positive blood and there are concerns that subsequent
pregnancies will trigger an immune response.
What are the genotypes of the mother and her first baby?
Genotype of mother
A.
Rh Rh
Rh Rh
B.
Rh Rh
Rh Rh
C.
Rh Rh
Rh Rh
D.
Rh Rh
Rh Rh
(Total 1 mark)
3.
What is the difference between the origin of type I and type II diabetes?
Type I
Type II
A.
B.
starts in childhood
C.
D.
IB Questionbank Biology
4.
Up to two additional marks are available for the construction of your answers.
(2)
(a)
(b)
(c)
5.
In the nucleus
B.
In the cytoplasm
C.
D.
6.
B.
C.
D.
7.
(a)
IB Questionbank Biology
......................................................................................................................................
(1)
(b)
(c)
(d)
Outline why antibiotics are effective against bacteria but not against viruses.
......................................................................................................................................
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(2)
(Total 5 marks)
8.
Up to two additional marks are available for the construction of your answers.
(2)
(a)
(b)
(c)
IB Questionbank Biology
(8)
(Total 20 marks)
IB Questionbank Biology
9.
Rhesus factor is an antigen present on the surface of red blood cells of Rhesus positive
individuals.
+
Rhesus positive (Rh ) is dominant to Rhesus negative (Rh ). A mother with Rhesus negative
blood gives birth to a baby with Rhesus positive blood and there are concerns that subsequent
pregnancies will trigger an immune response.
What is a possible explanation for why subsequent pregnancies could trigger an immune
response?
+
A.
B.
Exposure to the Rh antigen in the first pregnancy triggered the development of specific
+
phagocytes that could attack the blood of a future Rh baby.
C.
D.
(Total 1 mark)
10.
Up to two additional marks are available for the construction of your answers.
(2)
(a)
(b)
(c)
Explain the principle of homeostasis with reference to the control of body temperature.
(9)
(Total 20 marks)
11.
Up to two additional marks are available for the construction of your answers.
(2)
(a)
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(b)
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(c)
12.
Neutrophils are a primary defence against bacterial and fungal infection. This defence involves
both phagocytosis and hydrogen peroxide production. If there is an excess production of
hydrogen peroxide, tissue damage may occur.
In hospitals, intravenous feeding of patients is often necessary and lipids form an essential part
of the solutions used. A study was undertaken to measure the impact of two different types of
lipid solutions on the activity of neutrophils in blood samples and on their production of
hydrogen peroxide. The two lipid solutions were tested at two different concentrations,
3
3
0.06 mg cm (Graph A) and 0.6 mg cm (Graph B). The control has no lipid solutions.
[Source: Bjrn Jttner, Janina Krplin, Sina M Coldewey, Lars Witt, Wilhelm A Osthaus, Christian Weilbach, Dirk
Scheinichen. 2008. Unsaturated long-chain fatty acids induce the respiratory burst of human neutrophils and
monocytes in whole blood. Nutrition & Metabolism. Vol 5. P 19. 2008 Jttner et al; licensee BioMed Central Ltd]
(a)
Identify the maximum percentage value of neutrophils producing hydrogen peroxide for
3
the LCT-MCT solution at 0.06 mg cm .
......................................................................................................................................
(1)
IB Questionbank Biology
(b)
Compare the effects of the two different lipid solutions at the two different concentrations
on the percentage of neutrophils producing hydrogen peroxide.
......................................................................................................................................
......................................................................................................................................
......................................................................................................................................
......................................................................................................................................
......................................................................................................................................
......................................................................................................................................
......................................................................................................................................
(3)
(c)
(d)
Evaluate the data in terms of decisions for the intravenous feeding of patients.
......................................................................................................................................
......................................................................................................................................
......................................................................................................................................
......................................................................................................................................
......................................................................................................................................
......................................................................................................................................
......................................................................................................................................
(3)
(Total 8 marks)
IB Questionbank Biology
13.
Outline the roles of gastric acid and Helicobacter pylori in the development of stomach ulcers
and stomach cancers.
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(Total 6 marks)
14.
B.
C.
D.
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15.
Body mass index (BMI) is an important indicator of health. The relationship between a high
BMI and percentage risk of developing type II diabetes was studied and the following data
presented.
[Source: Colditz, G et al. 1995. Annals of Internal Medicine. Vol 122. P 481.]
(a)
Describe the effect of increased BMI on the risk of developing type II diabetes.
......................................................................................................................................
......................................................................................................................................
......................................................................................................................................
......................................................................................................................................
(2)
(b)
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10
(c)
Determine, by indicating on the graph, the range of age-adjusted relative risk for women
who are overweight but not obese.
(1)
(d)
Explain the dietary advice that should be given to a patient who has developed type II
diabetes.
......................................................................................................................................
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......................................................................................................................................
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......................................................................................................................................
......................................................................................................................................
(4)
(Total 8 marks)
16.
B.
C.
D.
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11
17.
The diagram below shows some stages in the production of monoclonal antibodies. What are
stages X, Y and Z?
[Used with the permission of Access Excellence @ the National Health Museum]
A.
injection of antibody
isolation of B-cell
B.
injection of antibody
isolation of T-cell
C.
injection of antigen
isolation of T-cell
D.
injection of antigen
isolation of B-cell
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12
18.
B.
Injection of antibodies
C.
Through colostrum
D.
Via placenta
(Total 1 mark)
19.
B.
C.
D.
20.
B.
C.
Only the genes that control the growth and development of a lymphocyte
D.
IB Questionbank Biology
13