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GALACTOCELE
Cystic dilation of
breast ducts
occurring during
lactation
Due to obstruction of
breast ducts by
inflammation and
fibrosis with
accumulation of milk
Pathogenesis :
1. Inflammation
with fibrosis
2. Obstruction of
the duct
3. Accumulation of
milk
Acute phase :
1. Lesion is tender.
Then it will
subside
2. CT shows
collection of
milky fluid
Later on :
1. Contents will be
inspissated and
cheesy
2. May rupture
causing a local
inflammatory
reaction
forming well
defined mass
breast cancer
Discharge of scanty
2. Fibrosis :
serous/serosangeous fluid
Stroma is composed of compressed fibrous tissue having lost its normal myxoid
from nipple
appearance
CLINICAL SIGNIFICANCE:
Cause
Infection of :
Staphylococcus aureus
Streptocooci
That pass through the cracks of the nipple
Obstruction of duct system by
inspissated secretion with stasis of
secretion
Breast engorged with milk good
medium for multiplication of
organism & suppuration will occur
Staph infection single / multiple
abscess
Strep infection wide spread
suppuration throughout entire
breast
Swollen and red
Characteristic
Grossly
CHRONIC MASTITIS
(1. Mammary duct ectasia, Plasma cell mastitis)
Predominantly in postmenopausal women
RARELY OCCUR
FAT NECROSIS
After radiation therapy / antecedent trauma to
the breast
Trauma ; common in seat belt
Irradiation
Rupture of fat cell necrosis mass
Microscopic
CLINICALLY:
*Fibrosis may lead to
Indurations and retraction of the
nipple, mimicking the changes
causes by carcinomas
* painless breast mass
CLINICALLY;
Included in the differential
diagnosis of breast mass
** Painless mass
stimulating breast cancer