For a clearer market perspective

The Future of
Nutrigenomics
New opportunities in personalized
nutrition and food-pharma
collaboration

The CoNsumeR NuTRiTioN seRies

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Publication date

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January 2010

The Future of Nutrigenomics

New opportunities in personalized nutrition and food-pharma collaboration

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About us...

Business Insights has launched an exciting new set of strategic reports

that provide unique analysis of the clinical nutrition market. Drawing on
the depth of our in-house research on the food, drinks and pharmaceutical
markets and our network of industry experts, our analysis is the leading
source of insight on the future of consumer nutrition.
The consumer nutrition series looks beyond lifestyle-oriented
nutraceuticals to proactive health and clinical applications of food and
drinks products. As pharma, ingredients and FmCG companies
increasingly converge on added value nutritional products, this immature
market is becoming highly dynamic and presents a real opportunity for growth.
Against this backdrop the role of R&D in the food and drinks market will continue to grow as clinically proven
efficacy becomes a key point of differentiation. our research examines the key trends, analyzes the impact of
innovation and assesses emerging opportunities and the key players operating in the market to give our clients
the full picture on the future of consumer nutrition..

Report overview
The consumer environment is driving growth in the nutrition and health market.
over the past decade, consumers have become more concerned for their health
and are increasingly inclined to invest in DTC nutrigenetic tests to assess their risk
of disease and obtain dietary advice. healthcare providers too, are keen to shift
some of the burden of healthcare costs to individuals and recognize that the
personalization of nutrition may be beneficial. The health and nutrition market is
currently worth around $485 billion.
Nutrigenomics has the potential to impact various parts of the food chain
including the genetic modification of crops and animal feeds, the development
of nutrigenomic tests to monitor food safety and personalization of diets, as
well as the identification of nutritional supplements and nutrigenomic based
products which may offer potential health benefits.
The Future of Nutrigenomics is a new report published by Business insights
that provides reviews on the business strategies of leading companies
regarding the adoption of nutrigenomic technologies and establishment of
public-private partnerships. it also provides an insight into the potential
opportunities for biomarker discovery within the pharma and diagnostic
industry to personalize nutrition and medicine.

The CoNsumeR NuTRiTioN seRies

Pages
Figures

160
24

Tables

12

This report provides you

with an assessment of the
nutrigenomic testing market,
the leading companies and its
role in empowering
consumers to take an active
role in making dietary
decisions and maintaining
their health status...

The Future of Nutrigenomics

New opportunities in personalized nutrition and food-pharma collaboration

Key issues...

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The food market is changing: over the past decade, consumers have become more concerned for their
health and wellbeing. The roll of the food and drinks industry is changing and shifting towards a more
benefit driven and preventative approach. in order to respond to market dynamics the companies have
needed to adopt an open network model to gain access to innovative research and technologies which will
drive future product development.
Nutrigenomics and pharmacogenomics are related in their approach to identify subpopulations that
respond to treatment/nutrition. The application of these technologies may lead to the identification of
old and new ingredients that have beneficial effects for specific consumer groups, helping to maintain health
and wellness and leading to the personalization of treatment and diets. The scientific evidence is mounting
however, large scale clinical studies are needed to reinforce data which can be utilized initially in dietary
guidance and latterly to support health claims.
Nutrigenomic testing marketing is growing and has been fueled by consumer concern for their health
and the demand for genomic information. increasingly, consumers are inclined to invest in DTC
nutrigenomic tests to assess their health status and obtain dietary guidance. This market is currently estimated
to be worth us$730 million and growing by 20% per annum.
Market fragmentation: The uptake of nutrigenomics by the food and drinks industry has been limited
as the information derived from nutrigenomics is complex and commercial interpretation is economically
challenging and may be lead to market fragmentation - an unwelcome prospect unless it can be achieved
through value added, high gross margin consumer directed products but one that may bring new marketing
opportunities and innovation to the marketplace.
Regulations in this competitive marketplace are evolving to encourage innovation whilst protect
consumer safety, it is estimated that nutrigenomic based products are unlikely to reach the market for at
least 10-15 years which will enable the regulators to establish sufficient skills and framework to address market
needs

Your questions answered...

Which companies are involved in nutrigenomic
testing and how may they influence the uptake
of personalized nutrition?

What is the regulatory status of nutrigenomics

and how will changes in these regulations
affect the industry in the near future?

how are health and nutrition market leaders

applying nutrigenomic research in their R&D
programs to develop new products or create
new marketing opportunities?

What are the key drivers for health and

nutrition and the development of personalized
nutrition, now and in the future?

What potential opportunities exist between the

food and drinks industry and the pharma and
diagnostic industry to co-develop biomarkers
for the development of personalized nutrition
and medicine?

The CoNsumeR NuTRiTioN seRies

The Future of Nutrigenomics

New opportunities in personalized nutrition and food-pharma collaboration

Key findings
Synergies between the food and drinks and
pharma and diagnostic industry. Whilst this may
create opportunities it is also likely to create conflict as food
and drinks manufacturers force pharma companies to switch
to a more preventative strategy.
Robust and reproducible clinical studies will be
needed to support successful products. The results
will enable the manufacturer to clearly differentiate them
and target specific consumer groups.
Opportunities for growth for personalized
nutrition is also likely in various market segments
(ageing population) and therapeutic targets (non
communicable diseases) which will also be driven by growth
in emerging markets.
Regulatory changes in the food and drinks
industry. impending health claim regulation will force
food and drinks companies to substantiate claims and prove
the efficacy of certain ingredients and products including
nutrigenomics.

Use this report to...

Benchmark your strategies against leading
players in nutrigenomic research using the
reports competitive analysis of ingredients,
food and drinks and nutrigenomic testing
companies.
Identify points of convergence of the
pharma, diagnostic and food and drinks
markets which may offer new opportunities
for co development.
Understand the market drivers and
resistors impacting the adoption of
nutrigenomic information and the
personalization of nutrition.

The CoNsumeR NuTRiTioN seRies

Figure 1.4: Applications of nutrigenomics in the food

chain
Nutrigenomics has the potential to impact various parts
of the food chain including the genetic modifications of
crops and animal feeds with enhanced nutrition (e.g.
omega 3, PuFA), the development of nutrigenomic tests
to monitor food safety and personalized nutrigenetic
diagnostic tests and the identification of nutritional
supplements and nutrigenomic based products with
health benefits...

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Gain insight into the leading companies,
their key products and business alliances
which enable them to participate in this
evolving field of science.
Review current and impending regulation
and gain insight into the effect of these
regulations on the industry in the near future.

The Future of Nutrigenomics

New opportunities in personalized nutrition and food-pharma collaboration

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report NOW

Table of Contents
ExECUTIvE SUMMARY

introduction

Defining nutrigenomics

introduction

Nutrigenomic research consortia

- Nutrigenomic research in the eu
- The european Nutrigenomics
organization (NuGo)
- DioGenes
- Ti Food and Nutrition
- Vision epiFood Project
- Canada Foundation for
innovation (CFi)
- Public-private in age-related
diseases
- Nutrigenomic research in the us
- Public-private partnership:
genetically modified crops
- Nutrigenomic research across the
world
- international society of
Nutrigenetics/Nutrigenomics
(isNN)

omic technologies

Conclusions

market drivers
Collaborative nutrigenomic research
& consortia
Leading food & drinks companies:
nutrigenomic strategies
Leading nutrigenomic testing
companies
opportunities: convergence of
pharma & diagnostics
Challenges: regulation, ethical & iP
issues
Conclusions

ChAPTER 1 DEFINING
NUTRIGENOMICS
summary

Nutrigenomics and the food & drinks

industry
Nutrigenomics & food products
Nutrigenomics & personalized
nutrition
Report outline

ChAPTER 4 lEADING FOOD &

DRINKS COMPANIES:
NUTRIGENOMIC STRATEGIES
summary
introduction

ingredients manufacturers approach

to nutrigenomics
ChAPTER 2 MARKET DRIvERS
Use this information to
- BAsF
summary
look at what is driving the
- Chr hansen
demand for nutrigenomic
introduction
Dsm
products
Drivers for personalized nutrition
Food manufacturers approach to
- healthy aging
nutrigenomics
- Consumer demographics
- Group Danone
- Chronic non-communicable
- Nestl
disease
- unilever
- urbanization and the emerging
Pharma industry m&A in consumer
markets
nutrition
- Global health economics
The evolving open network model
- Conclusions on drivers for
Co-development opportunities
personalized nutrition

ChAPTER 3 COllABORATIvE
NUTRIGENOMIC RESEARCh
& CONSORTIA

ChAPTER 5 lEADING
NUTRIGENOMIC TESTING
COMPANIES
summary
introduction
market leaders
- 23andme.com
- GeneLink
- Gene smart
- Genova Diagnostics
- interleukin Genetics inc
- WellGen inc.
Conclusions

ChAPTER 6 OPPORTUNITIES:
CONvERGENCE OF PhARMA
& DIAGNOSTICS
summary
introduction
Nutrigenomics vs
pharmacogenomics

Look at how
pharmaceutical
and food and
drinks companies
are collaborating

Global health issues treatment vs

prevention
Convergence of the pharmaceutical
& diagnostic market
Conclusions

ChAPTER 7 ChAllENGES:
REGUlATION, EThICAl & IP
This chapter will help
ISSUES
summary

you look at the impact

of regulation on the
future of nutrigenomics

introduction
- Regulation of nutrigenomic foods
- europe
- Japan
- Regulation of nutrigenomic tests
- ethical issues
- Public awareness & perceptions
- intellectual Property
Conclusions

Areas for market growth & time

scales

ChAPTER 8 CONClUSIONS

Conclusions

summary

summary

The CoNsumeR NuTRiTioN seRies

The food & drinks market

Global genetic testing market

The Future of Nutrigenomics

New opportunities in personalized nutrition and food-pharma collaboration

Click here to ORDER this

report NOW

Table of Contents
market trends
overall conclusions

Nutrigenomics vs
pharmacogenomics

APPENDIx

Relationship of drugs, disease,

genes and gene products

Primary research methodology

Acknowledgments
Glossary
index

health and nutrition market

segments (2009)
Nutrigenomic impact on
personalized nutrition

Bibliography

lIST OF TABlES

endnotes

european Consortia and

Nutrigenomic Research Programs

lIST OF FIGURES

Nutrigenomics Network Programs

Nutrigenetics and nutrigenomics

stakeholders in nutrigenomic
research and personalized nutrition

The omics technologies

The functional genomic tool box
Applications of nutrigenomics in the
food chain

Chr hansen - strategic alliances &

investments

Drivers for the food & drinks industry

Nestl nutrigenomic alliances &

investments

The ageing population a driver for

personalized nutrition

Divestment of Animal, Consumer &

medical Nutrition Divisions

Personalized nutrition targeting

consumer segments

Consumer health Divisions of

Pharmaceutical Companies

Population over 60: world and

developed regions (1950-2050)

Alliance between Food, Pharma,

Biotech and the Diagnostic
industries

Nutritional challenges obesity &

metabolic syndrome
Growth in consumers in developing
& emerging countries (2008-2018)
healthcare expenditure as a share of
GDP (2006)
Target population of nutrigenomic
based products
BAsF approach to gene discovery

Categorization of genetic variations

that may be included in
nutrigenomic tests
Categorization of genetic variations
that may be included in
nutrigenomic tests
Known diet- gene interactions
Known gene-nutrient interactions

Dsms sales growth targeting four

emerging business areas
Dsms R&D competencies
An international and interdisciplinary
network
Diversify & de-risk through
externalization
open network model
Waves of nutrigenomic development
WellGens nutrigenomic based
discovery

The CoNsumeR NuTRiTioN seRies

Review the business strategies of leading

companies regarding the adoption of
nutrigenomic technologies using this report....

The Future of Nutrigenomics

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