You are on page 1of 5

1.

*** - European Pharmacopoeia, 5th edition, 2005: 2184-2185


2. *** - Farmacopeea Romn, Ediia a 10-a, Editura Medical, Bucureti, 1993: 728-729,
356-358
3. A.N. Cristea Tratat de farmacologie, Editura Medical, 2006, ediia 1: 190-191, 618-624
4. Altman R. The American Journal of Medicine. Inflammatory Disease and the Role of
Voltaren (Diclofenac Sodium), 1986, 80(4), 48-52
5. Anker AL, Smilkstein MJ. Acetaminophen. Concepts and controversies. Emerg Med Clin
North Am. May 1994;12(2):335-49.
6. Bales, JR; Nicholson JK; Sadler PJ - Two-dimensional proton nuclear magnetic resonance
"maps" of acetaminophen metabolites in human urine. Clinical Chemistry, 1985, 31 (5):
757762
7. Bennwrth B., Phourcq F. Drugs. Pharmacologic basis for using paracetamol:
pharmacokinetic and pharmacodynamic issues, 2003, 63(2), 5-13
8. Bertolini A, Ferrari A, Ottani A, Guerzoni S, Tacchi R, Leone S. Paracetamol: new vistas of
an old drug. CNS Drug Reviews, 2006, 12 (34): 250275
9. Bort R, Ponsoda X, Jover R, Gmez-Lechn MJ, Castell JV - Diclofenac toxicity to
hepatocytes: a role for drug metabolism in cell toxicity. J Pharmacol Exp Ther, 1999, 288
(1): 65-72
10. Botha B, Mller FO, Krueger FGM, Melnitzky H, Vermaak L, Louw L - Quantitative
assessment of analgesia conferred by various analgesics, as determined by blocking the intraarterial bradykinin-evoked pain-response in the rat. Eur J Pharmacol, 1969, 6, 312321
11. Brandt KD, Mazzuca SA, Buckwalter KA - Acetaminophen,like conventional NSAIDs, may
reduce synovitis in osteoarthriticknees. Rheumatology (Oxford), 2006, 45, 13891394
12. Brater DC - Renal effects of cyclooxygyenase-2-selective inhibitors. J Pain Symptom
Manage, 2002, 23 (4): 1520
13. Brodie, BB; Axelrod J - The estimation of acetanilide and its metabolic products, aniline, Nacetyl p-aminophenol and p-aminophenol (free and total conjugated) in biological fluids and
tissues. J. Pharmacol. Exp. Ther,1948, 94 (1): 2228
14. Cahn, A; Hepp P - Das Antifebrin, ein neues Fiebermittel. Centralbl. Klin. Med., 1886, 7:
561564
15. Craig P.N. - Drug compendium. In: Hansch C, Sammes PG,Taylor JB (eds) Comprehensive
medicinal chemistry. Pergamon, Oxford, 1990, 245
16. Crawley B, Saito O, Malkmus S et al - Acetaminophen prevents hyperalgesia in central pain
cascade. Neurosci Lett, 2008, 442, 5053
17. D. Schapira, L. Bassan, A.M. Nahir, Y. Scharf Postgraduate Medicine journal. Diclofenacinduced hepatotoxicity, 1986, 62: 63-65

18. Donovan JW. Nonsteroidal anti-inflammatory drugs. In: Shannon MW, Borron SW, Burns
MJ, eds. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose.
4th ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 51.
19. Dutta NK, Annadurai S, Mazumdar K, Dastidar SG, Kristiansen JE, Molnar J, Martins M,
Amaral L, The anti-bacterial action of diclofenac shown by inhibition of DNA synthesis. Int.
J. Antimicrob. Agents, 2000, 14 (3): 249251
20. EM Glenn, BJ Bowman, NA Rohloff - Agents and actions. Anti-inflammatory and PG
inhibitory effects of phenacetin and acetaminophen, 1977, 7(5-6): 513-516
21. Etminan M, Sadatsafavi M, Jafari S, Doyle-Waters M, Aminzadeh K, Fitzgerald JM Acetaminophen use and the risk of asthma in children and adults: a systematic review and
metaanalysis. Chest, 2009, 136, 13161323
22. FDA. FDA Drug Safety Communication: FDA warns of rare but serious skin reactions with
the pain reliever/fever reducer acetaminophen. US Food and Drug Administration. Available
at http://www.fda.gov/Drugs/DrugSafety/ucm363041.htm#. Accessed Aug 13 2013
23. Forrest J.A., Clements J.A., Prescott L.F. Clinical pharmacokinetics. Clinical
pharmacokinetics of paracetamol, 1987, 7 (2), 93-107
24. Fowler PD, Shadforth MF, Crook PR, John VA - Plasma and synovial fluid concentrations of
diclofenac sodium and its major hydroxylated metabolites during long-term treatment of
rheumatoid arthritis. Eur. J. Clin. Pharmacol., 1983, 25 (3): 38994
25. Gan TJ Current Medicine Research Opin. Diclofenac: an update on its mechanism of
action and safety profile, 2010, 26(7): 1715-1731
26. Garry G. Graham, Michael J. Davies, Richard O. Day, Anthoulla Mohamudally, Kieran F.
Scott Inflammopharmacology. The modern pharmacology of paracetamol: therapeutic
actions, mechanism of action, metabolism, toxicity and recent pharmacological findings,
2013, 21, 201-232
27. Graham D - COX-2 inhibitors, other NSAIDs, and cardiovascular risk: the seduction of
common sense. JAMA, 2006, 296 (13): 16531656
28. Graham GG, Robins S-A, Bryant KJ, Scott KF - Inhibition of prostaglandin synthesis in
intact cells by paracetamol (acetaminophen).Inflammopharmacology, 2001, 9, 131142
29. Henderson AJ - Prenatal and infant acetaminophen exposure,antioxidant gene
polymorphisms, and childhood asthma. J Allergy Clin Immunol, 2010, 126(1141), 1148
30. Hsin-Wei Kuo, Shang-Shyue Tsai, Mao-Meng Tiao, Yi-Chun Liu, I-Ming Lee, Chun-Yuh
Yang. - Analgesic use and the risk for progression of chronic kidney disease.
Pharmacoepidemiology and Drug Safety, 2010, 19:7, 745-751

31. Josephine Lai, Frank Porreca, John C. Hunter , Michael S. Gold - Annual Review of
Pharmacology and Toxicology. Voltage-gated sodium channels and hyperalgesia, 2004, 44:
371-397
32. LA Garcia Rodriguez, H. Jick The Lancet. Risk of upper gastrointestinal bleeding and
perforation associated with individual non-steroidal anti-inflammatory drugs, 1994,
343(8900): 769-772
33. Landau, Ralph; Achilladelis, Basil; Scriabine, Alexander - Pharmaceutical Innovation:
Revolutionizing Human Health. Chemical Heritage Foundation, 1999, 248249
34. Larson AM, Polson J, Fontana RJ, Davern TJ, Lalani E, Hynan LS, Reisch JS, Schidt FV,
Ostapowicz G, Shakil AO, Lee WM; Acute Liver Failure Study Group. Acetaminopheninduced acute liver failure: results of a United States multicenter, prospective study.
Hepatology (Baltimore, Md.), 2005, 42 (6): 13641372
35. Lester D, Greenberg LA, Carroll RP - The metabolic fate of acetanilid and other aniline
derivatives: II. Major metabolites of acetanilid appearing in the blood. J. Pharmacol. Exp.
Ther. 90, 1947, (1): 6875
36. Li S, Dou W, Tang Y, Goorha S, Balou LR, Blatteis CM - Acetaminophen: antipyretic or
hypothermic in mice? In either case, PGHs-1b is irrelevant. Prostaglandins Lipid Mediat,
2008, 85,8999
37. Linden CH, Rumack BH - Acetaminophen overdose. Emergency medicine clinics of North
America, 1984, 2 (1): 10319
38. M. Mockenhaupt, J.P. Kelly, D. Kaufman, Robert S Stern The Journal of Rheumatology.
The risk of Stevens-Johnson syndrome and toxic epidermal necrolysis associated with
nonsteroidal antiinflammatory drugs: a multinational perspective, 2003, 30(10): 2234-2240
39. Martin G.M., Stockfleth E. Diclofenac sodium 3% gel for the management of actinic
keratosis: 10+ years of cumulative evidence of efficacy and safety. J Drugs Dermatol.
2012;11:600608
40. Milena Lesna, A.J. Watson, AdrianP. Douglas, A.N. Hamlyn, Oliver James, E.N. Wardle, R.
Chenery, C. Fisher, A.E.M. Mclean Toxicity of paracetamol. The Lancet, 1976, 307(7952):
191
41. Milton AS J Pharm Pharmacol. Modern views on the pathogenesis of fever and the mode
of action of antipyretic drugs, 1976, 28(4), 393-399
42. Milton Silverman, Mia Lydecker, Philip Randolph Lee - Bad Medicine: The Prescription
Drug Industry in the Third World. Stanford University Press. pp., 1992, 8890
43. Morse HN - Ueber eine neue Darstellungsmethode der Acetylamidophenole. Berichte der
deutschen chemischen Gesellschaft (in German), 1878, 11(1): 232233
3

44. Mycek M.J, Harvey R.A., Champe P.C. Seciunea II i III (SNV i SNC), Lippincott's
Illustrated Reviews Pharmacology, 2

nd

ed., Lippincott Williams-Wilkins, Baltimore, 1997

(ed. n lb.rom., 2000): 81-150


45. Neal M. Davies, Keith E. Anderson Clinical Pharmacokinetics of Diclofenac. Clinical
Pharmacokinetics, 1997, 33(3): 184-213
46. Nikles JC, Yelland M, Del Mar C, Wilkinson D - The role of paracetamol in chronic pain: an
evidence-based approach. Am J Ther, 2005, 12, 8091
47. Ozkaya O, Genc G, Bek K, Sullu Y. A case of acetaminophen (paracetamol) causing renal
failure without liver damage in a child and review of literature. Ren Fail. 2010;32(9):11251127
48. P. N. Praveen Rao1, Edward E. Knaus - Evolution of Nonsteroidal Anti-Inflammatory Drugs
(NSAIDs): Cyclooxygenase (COX) Inhibition and Beyond. J Pharm Pharmaceut Sci, 2008,
11(2): 81-110
49. Peter A. Todd, Eugene M. Sorkin - Diclofenac sodium. Drugs, 1988, 35 (3): 244-285
50. Prescott L.F. American journal of therapeutics. Acetaminophen: past, present, and
future, 2000 (7), 143-147
51. R. N. Brogden, R. C. Heel, G. E. Pakes, T. M. Speight, G. S. Avery Drugs. Diclofenac
Sodium: A Review of its Pharmacological Properties and Therapeutic Use in Rheumatic
Diseases and Pain of Varying Origin, 1980, 20(1): 24-48
52. Rapoport, Alan - Headache Relief. Touchstone., 1991: 97
53. Sallmann AR The history of diclofenac. Am J Med, 1986, 80 (4): 29-33
54. Sara I. Brjesson, Fredrik Elinder Cell Biochemistry and Biophysics. Structure, Function,
and Modification of the Voltage Sensor in Voltage-Gated Ion Channels, 2008, 52(3): 149-174
55. Shaheen SO, Newson RB, Ring SM, Rose-Zerilli MJ, Holloway JW,
56. Sheen C, Dillon J, Bateman D, Simpson K, Macdonald T - Paracetamol toxicity:
epidemiology, prevention and costs to the health-care system. QJM : monthly journal of the
Association of Physicians, 2002, 95 (9): 60919
57. Sneader, Walter - Drug Discovery: A History. Hoboken, N.J.: Wiley, 2005, p. 439
58. Tang W. Current Drug Metabolism. The Metabolism of Diclofenac Enzymology and
Toxicology perspectives, 2003, 4(4): 319-329
59. Thomas G., Kantor M.D. The American Journal of Medicine Use of Diclofenac in
analgesia, 1986, 80(4): 64-69
60. Tong J. Gan Diclofenac: an update on its mechanism of action and safety profile, 2010,
26(9): 1715-1731
61. US Food and Drug Administration. Organ-specific warnings: internal analgesic, antipyretic,
and antirheumatic drug products for over-the-counter human use. Federal Register. 2009 Apr
29;74(81)
4

62. V.V. Nikonov, A.N. Nudga Diclofenac in clinical practice (Literature review), 2006, 6(7):
102-104
63. Von Mering J. - Beitrage zur Kenntniss der Antipyretica. Ther Monatsch, 1893, 7: 577587
64. Williams HJ, Ward JR, Egger MJ et al - Comparison of naproxen and acetaminophen in a
two-year study of treatment of osteoarthritis of the knee. Arthritis Rheum, 1993, 36, 1196
1206
65. Yilmaz B., Asci A., Palabiyik S.S. HPLC method for determination of diclofenac in human
plasma and its application to a pharmacokinetic study in Turkey. J Chromatogr Sci.
2011;49:422427
66. Zhi-Gang Xiong, Giuseppe Pignataro, Minghua Li, Su-youne Chang, Roger P Simon
Current Opinion in Pharmacology. Acid-sensing ion channels (ASICs) as pharmacological
targets for neurodegenerative diseases, 2008, 8(1): 25-32