Академический Документы
Профессиональный Документы
Культура Документы
Department of Microbiology, 2Department of Forensic Medicine, Institute of Medical Sciences, Banaras Hindu
University, Varanasi-221005, India.
Abstract
Cutaneous fungal infections are a widespread public health concern affecting millions of people all across the world.
Nearly half of those affected will experience multiple episodes of infection requiring numerous rounds of treatment.
Tinea pedis is a common superficial fungal skin infection of the feet. It is emerging as an important and a significantly
prevalent infection in an increasingly aging population and immunocompromised patients. This mycotic infection is
contagious, frequently misdiagnosed and often inadequately treated. Considering the uprising prevalence of tinea
pedis, in this review article predisposing factors, etiologic agents involved in pathogenesis, clinical presentation of
the disease, proper diagnostic tests and the treatment options commercially available are reviewed.
Key Words: Tinea pedis; Dermatophytes; KOH Mount; PAS Reaction
1. Introduction
4. Clinical Presentation
There are four distinct clinical types of tinea pedis - interdigital, hyperkeratotic, ulcerative and vesicular, each with
a characteristic pattern of skin manifestations. (Fig. 1)
5. Differential Diagnosis
In clinical practise, diagnosis of tinea pedis is often
based on clinical presentation, direct microscopic examination of skin scrapings and mycology culture.15 Dermatophytosis of the foot may be symptom of a number
of conditions similar in appearance to tinea pedis, reinforcing the need to positively identify infection through
testing. The clinical differential diagnosis of cutaneous
eruptions of the foot includes many look-alike conditions, such as contact dermatitis, psoriasis, dyshydrosis,
eczema, atopic dermatitis, keratoderma, lichen planus
and some bacterial infections like C. minutissimum,
Streptococcal cellulitis etc. are also commonly confused
with tinea pedis.
6. Laboratory Diagnosis
FORMULATION
FUNGICIDAL OR
FUNGISTATIC
FREQUENCY OF
APPLICATION
1 % cream,
gel
Fungicidal
Once or twice
daily
1% cream
Fungicidal
1% cream
Fungistatic
Once or twice
daily
Fungistatic
Twice daily
Once or twice
daily
2% cream
1% cream
9. References
1. Masri-fridling GD. Dermatophytosis of the feet.
Dermatologic Clinics.1996; 14:33-40 http://
dx.doi.org/10.1016/S0733-8635(05)70322-3
2. Odom RB.Pathophysiology of dermatophyte
infections. Journal of the American Academy of
Dermatology; 1993; 28 Supplement: S2-S7
http://dx.doi.org/10.1016/S0190-9622(09)80300-9
3. Bell-Syer SE, Hart R et al. Oral treatments for fungal
infections of the skin of the foot. Cochrane Database
Systematic Reviews 2002; 8(2):CD003584
4. Leyden J L. Tinea pedis: Pathophysiology and
treatment. Journal of the American Academy of
Dermatology 1994; 31 (3 Pt 2): S31-S3 http://
dx.doi.org/10.1016/S0190-9622(08)81264-9
5. Maruyama R, Hiruma M., Yamauchi K et al. An
epidemiological and clinical study of untreated
patients with tinea pedis within a company of Japan.
Mycoses 2003; 46:208-12.http://dx.doi.org/10.1046/
j.1439-0507.2003.00864.x PMid:12801364
6. Ogasawara Y, Hiruma M et al. Clinical and
mycological study of occult tinea pedis and Tinea
unguium in dermatological patients from Tokyo.
Mycoses 2003; 46:114-9 http://dx.doi.org/10.1046/
j.1439-0507.2003.00855.x PMid:12870199
7. Loo D S. Cutaneous fungal infections in the elderly.
Dermatologic
Clinics
2004;
22:33-50.
http://dx.doi.org/10.1016/S0733-8635(03)00109-8
8. Rinaldi M G. Dermatophytosis: Epidemiological and
Microbiological update. Journal of the American
Academy of Dermatology 2000; 43: S120-S24.
http://dx.doi.org/10.1067/mjd.2000.110378
9. Carlo CJ, Mac Williams Bowe P. Tinea pedis (athlete?s
foot) 2007. Available at: http://www.bhchp.org.
10. Al Hasan M. Fitzgerald SM et al .Dermatology for the
practicing allergist: tinea pedis and its complications, Clinical and Molecular Allergy 2004; 2:5
http://dx.doi.org/10.1186/1476-7961-2-5
PMid:15050029 PMCid:419368
11. Hainer B L., Dermatophyte infection. American Family Physician 2003; 67:101-8. PMid:12537173
12. Rich P. Harkless LB et al. Dermatophyte test medium
culture for evaluating toe nail infections in patients
with diabetes. Diabetes care 2003; 26(5):1480-4.
http://dx.doi.org/10.2337/diacare.26.5.1480
PMid:12716808