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developmental
milestones,
hypothermia
and
hypoglycaemia
dysplasia),
retinopathy
of
prematurity,
impairment, and sudden death (Do, P., Lin, EC. et. al.2014).
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neurologic
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Case Objectives
General Objective:
This study aims to determine what is hyaline membrane disease
specifically in the newborn.
Specific Objectives:
1) Discuss the introduction of the disease including its incidence and
2)
3)
4)
5)
of each part;
6) Trace the pathophysiology of the disease
7) Enumerate and conduct a drug study on drugs administered to the
patient with its pharmacological uses and effects as well as nursing
responsibilities to be observe in relation to the patients condition;
8) Formulate effective nursing care plans;
9) Discuss the prognosis about the case with its justification;
DEFINITION OF DIAGNOSIS
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surfactant
is
complex
lipoprotein
composed
of
HEALTH HISTORY
Biographical Data
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Family History
Grandfath
er, 57 y.o,
Osteoporo
sis
Sister 1,
28 y.o,
well and
alive
Grandmother, 58
y.o, rheumatoid
arthritis
Kuya, 25
y.o,
alcoholic
, cough
Pts Mother,
19 y.o, well
and alive
Grandfath
er, 54 y.o,
Asthmatic
Kuya 1,
34 y.o,
well and
alive
Patient, newborn, diagnosed
of having
Hyaline Membrane Disease
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Grandmother, 58
y.o, rheumatoid
arthritis
Pts
Father,
21 y.o,
well and
Sister, 32
y.o, well
and alive
Review of Systems
General Survey
The patient was manifesting difficulty of breathing, has an endotracheal
tube attached to him with mechanical ventilator, has no lesion, skin is intact,
positive blood secretion after pressing the ambobag. There was no mass on
head, neck and no signs of any injuries or fractures. His head and extremities
were flexed with a head circumference of 36 cm, chest circumference of 27
cm, abdominal circumference of 23 cm, weight of 1.5 kg, a height of 44 cm
and a rectal temperature of 36.8 C (manifest that his rectum is patent). His
respiratory rate was 86 cycles per minute with nasal flaring and has an
irregular heart beat that were playing at a minimum of 87 beats per minute and
a maximum of 146 beats per minute.
Integumentary System
No lesion was noted when the researcher conducted physical
assessment but was noted a cleft lip like shape that is maybe due to the ET
tube that was connected to the patient. His skin was dry but warmth to touch
with uneven skin tone and has a reddish color on his cheek. He has no signs
of cyanosis, there were cheesy like substances (vernix caseosa) on his neck,
his hair was equally distributed and his nails were already long.
HEENT
The patient was still a newborn. According to the mother, the baby has
symmetrical head and eyes with no eye exudates. When the patient called, he
turns to side but cant vocalize. There were no exudates on the nose.
Respiratory System
When the watchers asked about the patients breathing pattern, they
answered that sometimes they observe fast chest pumping and sometimes
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slow. According to the vital sign, his RR was 86 cycles per minute and it
indicates tachypnea since the normal range of respiratory rate in newborn was
30 60 cycles per minute only.
Cardiovascular System
When the mother was asked about the activity of her baby, she replied
usahay active, usahay dili (sometimes active but sometimes he isnt). she
didnt observed any bluish discoloration in the child.
Gastrointestinal
The mother told the researcher that the patient poops once but not
eating nor drinking yet.
Genitourinary
The patient was already urinates and consumed 1 diaper only.
Musculoskeletal
The patient was still a newborn. He has already positive in almost all
reflexes normally found in newborn.
Neurological
The patient was still a newborn. The mother told the researcher that
she didnt noticed any tremors or unusual movements of the baby but she was
worried because the baby did not suck yet.
Infections
The patient was still a newborn. There was no infection occurs yet as
evidenced by the latest temperature of 36.8 C with no other signs of infection.
But an increase of WBC on the lab results indicates that there are infection
present but the leukocytes of the patient is fighting it.
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Relationship
When the mother asked about what she feels about the baby, she
replied that they are happy because there were new gift they have had
received from god but lonely because of the situation of their baby.
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PSYCHOSOCIAL PROFILE
Health Practices and Beliefs
The patient was still a newborn. His mother claimed that she is
undergone a complete prenatal check-up in the hospital.
Typical Day
The patient was still a newborn.
Nutritional Pattern
The patient was still a newborn. His mother was eating nutritious food 3
times a day with 2 3 times of her snacks.
Activity and Exercise Pattern
The patient was still a newborn. Her mother was walking everyday
usually early in the morning.
Recreation and Hobbies
The patient was still a newborn.
Sleep/ Rest Pattern
The patient was still a newborn. His mother was waking up early in the
morning at around 5:00 am.
Personal Habits
The patient was still a newborn. Her mother was smoking occasionally
but not drinking alcoholic beverages.
The patient was still a newborn. Her mother was a vendor and
sometimes exposed to dust and sun for her husband is working at sand and
gravel and construction.
Environmental Health Patterns
Their environment can be described as not free with chemicals because
they are surrounded by farms. But they still observe sanitation.
Cultural/ Religious Influences
The patient was still a newborn.
religious influences, she answered that if its gods will then it will happen.
Family Roles and Relationships
He has a very supportive family. His mother didnt left him alone.
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PHYSICAL ASSESSMENT
Date Assessed: December 09, 2014
General Survey
Baby Boy L was asleep with an ongoing IVF of D10W + Ca infusing well
at right metacarpal vein. He has an ET Tube connected to mechanical
ventilator on his mouth.
Vital Signs
December 09, 2014 at 2:00 pm
Temperature 36.8C
Respiratory Rate (RR) - 86 cycle per minute (cpm)
Pulse Rate (PR) - 146 beats per minute (bpm)
Anthropometric Measurement
Head Circumference 36 cm
Chest Circumference 27 cm
Abdominal Circumference 23 cm
Weight 1.5 kg
Height 44 cm
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Head-to-Toe Scan
Assessing the Integumentary Systems
No lesion was noted when the researcher conducted physical
assessment but was noted a cleft lip like shape that is maybe due to the ET
tube that was connected to the patient. His skin was dry but warmth to touch
with uneven skin tone and has a reddish color on his cheek. He has no signs
of cyanosis, there were cheesy like substances (vernix caseosa) on his neck,
his hair was equally distributed and his nails were already long.
Assessing the HEENT
When his anterior fontanels was gently palpated, there was a diamond
shape like that the researcher was observed and a triangular shape like on the
posterior portion. He has soft face with symmetrical facial movements. He has
positive tonic reflex. His eyes are edematous maybe due to vaginal delivery
was occur, eyes were equal and symmetrical. His pinna ere flexible, without
deformity and aligns with the external canthus of the eyes. His nares were
patent with a small amount of white to colorless discharges.
Mucous
membrane were pink and moist, frenulum of tongue and lip were intact but
wasnt a good sucker, with minimal saliva and crying so loud but interrupted
sometimes.
Assessing the Chest
His chest when palpated has no lesion or masses noted. He has
anteroposterior:lateral chest with equal chest excursion but increases rapidly
due to difficulty of breathing.
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FOCUSED ASSESSMENT
Assessing the Respiratory System
His respiratory rate is 86 cycles per minute and it was above the normal
range. He was experiencing difficulty of breathing. Upon auscultation, there is
a scattered crackles heard on the chest. Cough reflex is absent and bronchial
and bronchovesicular breath sounds were audible.
Laboratory and Diagnostic Result
A. HEMATOLOGY
Date: 12 09 14
Table No.
Basic Test
Result
WBC
14.9
HGB
203
HCT
0.607
Reference
Values
5-10 x 10
g/L
M: 140 160g/L
F: 120 140g/L
M: 0.40
0.54
F: 0.37
0.47
Justification
High white blood cell count is an
increase in disease-fighting cells
(leukocytes) circulating in your
blood. High white blood cell count
is also called leukocytosis.
Low
count
of
hemoglobin
indicates a reduction in either the
number of size of RBCs. it may
implies that patient has anemia.
A high hematocrit means the
percentage of red blood cells in
a person's blood is above the
upper limits of normal and it can
cause:
Dehydration (heat exhaustion,
no available source of fluids)
Low availability of oxygen
(smoking,
high
altitude,
pulmonary fibrosis)
Genetic
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(congenital
heart
diseases)
Erythrocytosis
(overproduction of red blood cells
by
the
bone
marrow
orpolycythemia vera)
Monocytes
0.047
0.04 0.16
Lymphocyte
0.39
0.25 0.35
Cor
pulmonale
(COPD,
chronic sleep
apnea,
pulmonary
embolisms)
(Davis, 2014).
Normal
Elevated lymphocyte indicates
that the body has experienced an
invasion of foreign cells.
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Since the fetal lungs are fluid filled and do not contain oxygen, blood
passing through the lungs cannot pick up oxygen to deliver throughout the
body. Thus, blood flow through the lungs is markedly diminished compared to
that which is required following birth. Diminished blood flow through the lungs
of the fetus is a result of the partial closing of the arterioles in the lungs. This
results in the majority of blood flow diverted away from the lungs through the
ductus arteriosus.
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Birth
At birth, as the infant takes the first few breaths, several changes occur
whereby the lungs take over the lifelong function of supplying the body with
oxygen. In an attempt to establish normal respirations, the infant can develop
problems in two areas:
Fluid may remain in the alveoli;
Blood flow to the lungs may not increase as desired.
Fortunately, the first few breaths of most newborn infants are generally
effective, expanding the alveoli and replacing the lung fluid with air.
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PATHOPHYSIOLOGY
The primary cause of RDS is inadequate pulmonary surfactant. The
structurally immature and surfactant-deficient lung has decrease compliance
and a tendency to atelectasis; other factors in preterm infants that increase the
risk of atelectasis are decreased alveolar radius and weak chest wall. With
atelectasis, well perfused but poorly ventilated areas of lung lead to V/Q
mismatch (with intra-pulmonary shunting) and alveolar hypoventilation with
resultant hypoxemia and hypercarbia. Severe hypoxemia and systemic
hypoperfusion result in decreased O2 delivery, anaerobic metabolism and
subsequent lactic acidosis. Hypoxemia and acidosis may further impair
oxygenation by causing pulmonary vasoconstriction, resulting in right-to-left
shunting at the levels of the foramen ovale and ductus arteriosus. Other
factors, such as baro/volutrauma and high FIO2, may initiate release of
inflammatory cytokines and chemokines causing more endothelial and
epithelial cell injury. The injury results in reduced surfactant synthesis and
function as well as increased endothelial permeability leading to pulmonary
edema.
Leakage of proteins into the alveolar space further exacerbates
surfactant deficiency by causing surfactant inactivation. Macroscopically, the
lungs appear congested, atelectatic and solid. Microscopically, diffuse alveolar
atelectasis and pulmonary edema are seen. An eosinophilic membrane
composed of a fibrinous matrix of materials from the blood and cellular debris
(the hyaline membrane) lines the visible airspaces that usually constitute
dilated terminal bronchioles and alveolar ducts
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Diagram of Pathophysiology
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Drug Study
DRUG
MECHANISM
NAME
OF ACTION
Generic
Inhibits
Name:
mucopeptide
Ceftazidime
synthesis in
bacterial cell
Brand
wall.
Name:
Classificat
ion:
Antibiotic,
Cephalospo
rin
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DOSE/
ROUTE
Actual:
150 mg ivtt
INDICATION
Treatment
of infection
of lower
desired:
respiratory
IV : 45 to
tract, skin
90
and skin
mcg/mL(50
structure,ur
0 and 1 g
inary
doses)
tract,bone
IM:17 to 39
and
mcg/mL(50
joints:treat
0 and 1 g
ment of
doses)
gynecologi
cal
infection:tr
eatment of
intraabdominal
infections:
treatment
of
septicemia
and CNS
CONTRA
INDICATION
Hypersen
sitivity to
cephalosp
horin
SIDE
EFFECTS
ADVERSE
REACTIONS
GI
Nausea;
vomiting;
diarrhea;
anorexia;
abdominal pain
or cramps;
flatulence;
colitis, including
pseudomembra
nous colitis.
Genit
ourina
ry
Pyuria; renal
dysfunction;
dysuria;
reversible
NURSING
RESPONSIBILITIES
Assess for liver and
renal dysfunction
Culture infection,
and arrange
sensitivity tests
before and during
therapy if expected
response is not seen.
Warning:
Do not mix with
aminoglycoside
solutions, administer
these drugs
separately.
Powder and
reconstituted solution
darken with storage.
Have Vit. K
available in case
hypoprothrombinemi
a occurs
Discontinue if
hypersensitivity
occurs
Teach SO that
infections
including
meningitis
caused by
susceptible
strains and
specific
microorgan
isms:
concomita
nt antibiotic
therapy.
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interstitial
nephritis;
hematuria; toxic
nephropathy.
Hema
tologi
c
Eosinophilia;
neutropenia;
lymphocytosis;
leukocytosis;
thrombocytope
nia;
thrombocytosis;
decreased
platelet
function;
anemia;
aplastic
anemia;
hemorrhage.
patients may
experience upset
stomach or diarrhea
but must report
severe diarrhea,
difficulty breathing,
fatigue, pain at
injection site.
Hepatic
Hepatic
function
impairment;
cholestatic
jaundice;
abnormal LFT
results.
Miscellaneo
us
Hypersensitivity
, including
StevensJohnson
syndrome,
erythema
multiforme,
toxic epidermal
necrolysis;
candidal
overgrowth;
serum
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sicknesslike
reactions (eg,
skin rashes,
polyarthritis,
arthralgia,
fever); phlebitis;
thrombophlebiti
s, and pain at
injection site.
cc
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NEED
Date:12 09 14
Time: 04:30 pm
Activity
Exercis
e
Pattern
Subjective:
Usahay paspas
muginhawa, ti kulban
pud ko bai
Objectives:
Increased and
sometimes
decreased fast
chest expansion
Respiratory rate of
86 cycles per
minute
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NSG.
DIAGNOSIS
Ineffective
Airway
Clearance
related to
decreased
lung
expansion
due to fluid
accumulatio
n as
evidenced
by changes
of
repiratory
rate
PLAN
At the end
of 8 hr.
span of
my care
the pt. will
be able to
maintain
airway
patency.
NSG.
INTERVENTION
Assess and
monitor
Respiratory
rate
RATIONALE
Tachypnea is
usually present;
respirations maybe
shallow and rapid
with prolonged
expiration
compared to
inspiration.
Rapid onset of
acute dyspnea may
reflect pulmonary
embolus.
ASSESSMENT
Date:12 09 14
Time: 4:30 pm
Subjective:
Ara man sing makina
nga nakabutang sa
iyang baba tisahay
mabal-an ko nga lisod
siya kaginhawa
Objectives:
Episodes of
dyspnea
In ability to move
scretions.
NEED
NSG.
DIAGNOSIS
Activity Impaired
Gas
Exercise Exchange
Pattern
PLAN
At the end
of 8 hr.
span of my
care the pt.
will be able
demonstrat
e improved
ventilation
and
adequate
oxygenatio
n of tissues
by ABGs
within
clients
normal
range and
be free
from any
signs of
respiratory
distress..
NSG.
INTERVENTION
Observe for
localized signs
of infection at
surgical
infections.
Stress proper
hygiene.
Change
surgical
wound
dressing daily.
Emphasize
necessity of
taking
antibiotics as
directed.
To assess causative
or contributing
factors about
infection.
To limit exposures
and reduce
contamination
To reduce bacterial
colonization.
Premature
discontinuation of
treatment when clients
feel well may result in
return of infection and
potentiation of drug
resistantstrains.
To reduce potential
infection.
Includes
teaching about
ways to reduce
potential for
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RATIONALE
post operative
infection.
ASSESSMENT
Date: 12 09 - 14
Time: 4:30 pm
Subjective:
may ara sang tubo
nga gikabit sa akong
bata
Objectives:
ET Tube
attached to
the mouth of
the baby.
Redness and
swelling on
the sight
NEED
Health
percepti
on
health
manage
ment
pattern
NSG.
DIAGNOSIS
Risk for
trauma /
Suffocation
Scientific
basis:
Invasive
procedures
may
increased
risk for
trauma
PLAN
At the end
of 8 hr.
span of my
care the pt.
will be able
to
recognize
pts
watcher
need for
and seek
assistance
to prevent
complicatio
n.
NSG.
INTERVENTION
Observe for
localized signs
of infection at
surgical
infections.
Stress proper
hygiene.
Change
surgical
wound
dressing daily.
Emphasize
necessity of
taking
antibiotics as
directed.
RATIONALE
To assess causative
or contributing
factors about
infection.
To limit exposures
and reduce
contamination
To reduce bacterial
colonization.
Premature
discontinuation of
treatment when clients
feel well may result in
return of infection and
potentiation of drug
resistantstrains.
To reduce potential
infection.
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Includes
teaching about
ways to reduce
potential for
post operative
infection.
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Prognosis
Typically, the symptoms worsen a few days after birth but slowly
improve afterwards. The goal is to support the infant while the lungs begin
producing surfactant. Providing adequate nutritional requirements is also
important for recovery and growth.
Many infants with HMD suffer the complications of oxygen and
ventilation therapy but recover within the first couple of years of life as the lung
tissue is replaced with new and functional tissue.
Damage to other organs such as the brain may also occur which is due
to a combination of factors including hypoxia and intraventricular hemorrhage,
so it is imperative to begin therapy early and monitor organ damage
(UChicago, 2013).
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Bibliography
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Do,
P., Lin, EC. et. al. 2014. Hyaline Membrane Disease Imaging .
http://emedicine.medscape.com/article/409409-overview
ICNHF,
2004.
Respiratory
Disease
Syndrome.
http://www.ucsfbenioffchildrens.org
/pdf/manuals/25_RDS.pdf
LVHN, 2014. Lehigh Valley Hospital. Hyaline Membrane Disease.
http://www.lvhn.org/conditions_treatments/childrens_care/newborn_issu
es/hyaline_membrane_disease_respiratory_distress_syndrome/learn_a
bout_hyaline_membrane_disease/treatment
Mayoclinic,
2014.
High
white
blood
cells.
http://www.mayoclinic.org/symptoms/high-white-blood-cellcount/basics/definition/sym-20050611
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