Chapter 12: Benign Nonodontogenic Tumors

Test Bank
MULTIPLE CHOICE
1. A 33-year-old patient presents with a 1 2 cm swelling of the right side of his neck.
All of the following might be considered in a clinical differential diagnosis except:
a. Lymphadenitis
b. Salivary gland tumor in the tail of the parotid
c. Giant cell granuloma
d. Lymphoepithelial cyst
e. Lymphoma
ANS: C

REF: Chap 12 (Central giant cell granuloma), pp 303-306

2. A 21-year-old woman went to her dentist because of facial asymmetry. This had
occurred gradually over 3 years. The patient has had no symptoms. A diffusely opaque
lesion was found in her right maxilla. All lab tests (CBC, alkaline phosphatase,
calcium) were within normal limits. Biopsy was interpreted as a fibro-osseous lesion.
She most likely has:
a. Cementoblastoma
b. Fibrous dysplasia
c. Cherubism
d. Osteosarcoma
e. Chronic osteomyelitis
ANS: B

REF: Chap 12 (Fibrous dysplasia/Clinical features), p 297

3. A 16-year-old patient is found to have several well-defined radiopacities in his jaws.

The patient is asymptomatic and teeth are vital. These lesions could be which of the
following?
a. Central giant cell granulomas
b. Osteomas
c. Odontogenic keratocysts
d. Cherubism
e. None of the above
ANS: B

REF: Chap 12 (Osteoma), pp 300-301

4. Serum calcium would be significantly elevated in which of the following?

a. Central giant cell granuloma
b. Cherubism
c. Ameloblastoma
d. Langerhans cell disease (idiopathic histiocytosis) of the mandible
e. None of the above
ANS: E
REF: Chaps 11, 12, and 16 (Ameloblastoma/Langerhans cell disease/Central giant
cell granuloma/Cherubism), pp 270-277, pp 303-310 and pp 354-356

Copyright 2012, 2008, 2003, 1999, 1993, 1989 by Saunders, an imprint of Elsevier Inc.

Test bank

5. Which of the following conditions significantly increases a patients risk for

development of adenocarcinoma of the colon?
a. Albrights syndrome
b. Neurofibromatosis
c. Cleidocranial dysplasia
d. Gardners syndrome
e. None of the above
ANS: D

REF: Chap 12 (Osteoma/Clinical features), pp 300-301

6. Which of the following lesions would most likely present radiographically as

floating teeth in the jaw?
a. Odontoma
b. Osteoma
c. Ameloblastoma
d. Langerhans cell disease
e. Albers-Schonberg disease
ANS: D
REF: Chap 12 (Langerhans cell disease/Clinical features), pp 308-309
7. A 17-year-old patient had asymptomatic sharply defined punched out radiolucencies
of the body of the mandible subjacent to vital molar teeth. She also had related
lucencies in the cranium. Microscopically, the lesions consisted predominantly of
round cells with scattered eosinophils. This is descriptive of:
a. Cherubism
b. Multiple myeloma
c. Langerhans cell disease
d. Hyperthyroidism
e. Osteosarcoma
ANS: C
REF: Chap 12 (Langerhans cell disease/Histopathology/Box 12-12), pp 308-309
8. Ossifying fibroma:
a. May range radiographically from a lucent to a mixed lucent and opaque lesion
b. Is typically seen in young adults
c. Is composed of fibrous tissue with foci of new bone
d. Is associated with vital teeth
e. All the above
ANS: E

REF: Chap 12 (Ossifying fibroma), pp 294-296

9. All the following are components of McCune-Albright syndrome except:

a. Caf-au-lait macules
b. Intestinal polyps
c. Fibrous dysplasia
d. Precocious puberty
ANS: B

REF: Chap 12 (Fibrous dysplasia/Clinical features), p 297

Copyright 2012, 2008, 2003, 1999, 1993, 1989 by Saunders, an imprint of Elsevier Inc.

Test bank

10. A biopsy of a periapical lesion associated with a vital tooth showed CD1a-positive
round pale cells and many eosinophils. The diagnosis is:
a. Periapical abscess
b. Periapical granuloma
c. Solitary myeloma
d. Ewings sarcoma
e. Langerhans cell disease
ANS: E
309

REF: Chap 12 (Langerhans cell disease/Histopathology), p

11. The combination of multiple asymptomatic radiopaque jaw lesions with

supernumerary teeth and intestinal polyps is indicative of:
a. Nevoid basal cell carcinoma syndrome
b. Gardners syndrome
c. Diffuse sclerosing osteomyelitis
d. McCune-Albright syndrome
e. Langerhans cell disease
ANS: B

REF: Chap 12 (Osteoma/Clinical features), pp 300-301

12. The ossifying fibroma is characterized clinically by:

a. Slow growth
b. Well-defined borders
c. Benign fibro-osseous microscopic appearance
d. Appearance in young adults
e. All the above
ANS: E
295

REF: Chap 12 (Ossifying fibroma/Clinical features), pp 294-

13. A 20-year-old patient presents with increased mobility of only anterior mandibular
teeth. Extensive loss of alveolar bone is noted radiographically without evidence of
significant periodontal disease. The lesion is lucent with sharp margins. This would
suggest which of the following?
a. Cherubism
b. Gardners syndrome
c. Langerhans cell disease
d. Fibrous dysplasia
e. Pagets disease
ANS: C
REF: Chap 12 (Langerhans cell disease/Clinical features), pp 308-309
14. Which of the following could be classified as a benign fibro-osseous lesion?
a. Fibrous dysplasia
b. Idiopathic histiocytosis
c. Ewings tumor
d. Odontogenic myxoma

Copyright 2012, 2008, 2003, 1999, 1993, 1989 by Saunders, an imprint of Elsevier Inc.

Test bank

e. Hematopoietic bone marrow defect

ANS: A
REF: Chap 12 (Fibrous dysplasia/Boxes 12-1 and 12-2), pp 294, 296-299
15. Patients with central giant cell granulomas typically have which of the following
abnormal laboratory findings?
a. Elevated immunoglobulins
b. Elevated serum alkaline phosphatase
c. Elevated serum acid phosphatase
d. Elevated serum calcium
e. None of the above
ANS: E

REF: Chap 12 (Central giant cell granuloma), pp 303-306

16. A 22-year-old woman has spontaneous loss of teeth nos. 28, 29, and 30. She has no
periodontal pockets associated with the remainder of her teeth. Panoramic radiograph
shows a sharply defined radiolucency in the area of tooth loss as well as another
lucency in the body of her left mandible. She may have which of the following?
a. Cherubism
b. Cleidocranial dysplasia
c. Pagets disease
d. Hyperthyroidism
e. Langerhans cell disease
ANS: E
REF: Chap 12 (Langerhans cell disease/Clinical features), pp 308-309
17. A 15-year-old patient was found to have a 2 3 cm multiloculated radiolucent lesion
of his mandible. At the time of surgery, a solid, bloody lesion was removed.
Histologically, it was composed of benign-appearing fibroblasts and multinucleated
giant cells. This is most likely which of the following?
a. Hemangioma
b. Osteosarcoma
c. Peripheral giant cell granuloma
d. Central giant cell granuloma
e. Osteoporotic bone marrow defect
ANS: D
p 304

REF: Chap 12 (Central giant cell granuloma/Histopathology),

18. Ubiquitous dendritic cells, found within mucosa and epidermis and having the
function of processing foreign antigens and presenting relevant determinants to
immunocompetent cells are known as:
a. Macrophages
b. Langerhans cells
c. Langhans giant cells
d. Histiocytes
e. Plasma cells

Copyright 2012, 2008, 2003, 1999, 1993, 1989 by Saunders, an imprint of Elsevier Inc.

Test bank
ANS: B
307-310

5
REF: Chap 12 (Langerhans cell diseaseentire topic), pp

Copyright 2012, 2008, 2003, 1999, 1993, 1989 by Saunders, an imprint of Elsevier Inc.