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2 Pathophysiology
Causes
During urination, detrusor muscles in the wall of the bladder contract, forcing urine out of the bladder and into
the urethra. At the same time, sphincter muscles surrounding the urethra relax, letting urine pass out of the
body. Incontinence will occur if the bladder muscles suddenly contract (detrusor muscle) or muscles surrounding
the urethra suddenly relax (sphincter muscles).
2.1 Children
Main article: Enuresis
Urination, or voiding, is a complex activity. The bladder is a balloonlike muscle that lies in the lowest part of
the abdomen. The bladder stores urine, then releases it
through the urethra, the canal that carries urine to the outside of the body. Controlling this activity involves nerves,
muscles, the spinal cord and the brain.
The bladder is made of two types of muscles: the detrusor, a muscular sac that stores urine and squeezes to
empty, and the sphincter, a circular group of muscles at
Enlarged prostate is the most common cause of inthe bottom or neck of the bladder that automatically stay
continence in men after the age of 40; sometimes
contracted to hold the urine in and automatically relax
prostate cancer may also be associated with urinary
when the detrusor contracts to let the urine into the ureincontinence. Moreover drugs or radiation used to
thra. A third group of muscles below the bladder (pelvic
[4]
treat prostate cancer can also cause incontinence.
oor muscles) can contract to keep urine back.
A babys bladder lls to a set point, then automatically
Disorders like multiple sclerosis, spina bida, contracts and empties. As the child gets older, the nerParkinsons disease, strokes and spinal cord injury vous system develops. The childs brain begins to get
can all interfere with nerve function of the bladder. messages from the lling bladder and begins to send mes1
3 DIAGNOSIS
sages to the bladder to keep it from automatically empty- Research projects that assess the ecacy of antiing until the child decides it is the time and place to void. incontinence therapies often quantify the extent of uriFailures in this control mechanism result in incontinence. nary incontinence. The methods include the 1-h pad
Reasons for this failure range from the simple to the com- test, measuring leakage volume; using a voiding diary,
counting the number of incontinence episodes (leakage
plex.
episodes) per day; and assessing of the strength of pelvic
oor muscles, measuring the maximum vaginal squeeze
pressure.
Diagnosis
Types
A careful history taking is essential especially in the pattern of voiding and urine leakage as it suggests the type
of incontinence faced. Other important points include
straining and discomfort, use of drugs, recent surgery,
and illness.
The physical examination will focus on looking for signs
of medical conditions causing incontinence, such as tumors that block the urinary tract, stool impaction, and
poor reexes or sensations, which may be evidence of a
nerve-related cause.
A test often performed is the measurement of bladder capacity and residual urine for evidence of poorly functioning bladder muscles.
Other tests include:
Stress test the patient relaxes, then coughs vigor- Urinary incontinence may be caused by alcohol intoxication.
ously as the doctor watches for loss of urine.
Stress incontinence, also known as eort inconti Urinalysis urine is tested for evidence of infection,
nence, is due essentially to insucient strength of
urinary stones, or other contributing causes.
the pelvic oor muscles to prevent the passage of
urine, especially during activities that increase intra Blood tests blood is taken, sent to a laboratory, and
abdominal pressure, such as coughing, sneezing, or
examined for substances related to causes of inconbearing down.
tinence.
Ultrasound sound waves are used to visualize the
kidneys, ureters, bladder, and urethra.
Cystoscopy a thin tube with a tiny camera is inserted in the urethra and used to see the inside of
the urethra and bladder.
Urodynamics various techniques measure pressure
in the bladder and the ow of urine.
Patients are often asked to keep a diary for a day or more,
up to a week, to record the pattern of voiding, noting
times and the amounts of urine produced.
Urge incontinence is involuntary loss of urine occurring for no apparent reason while suddenly feeling
the need or urge to urinate.
Overow incontinence: Sometimes people nd that
they cannot stop their bladders from constantly dribbling or continuing to dribble for some time after
they have passed urine. It is as if their bladders
were constantly overowing, hence the general name
overow incontinence.
Mixed incontinence is not uncommon in the elderly female population and can sometimes be complicated by urinary retention, which makes it a
3
treatment challenge requiring staged multimodal
treatment.[5]
Structural incontinence: Rarely, structural problems
can cause incontinence, usually diagnosed in childhood (for example, an ectopic ureter). Fistulas
caused by obstetric and gynecologic trauma or injury are commonly known as obstetric stulas and
can lead to incontinence. These types of vaginal
stulas include, most commonly, vesicovaginal stula and, more rarely, ureterovaginal stula. These
may be dicult to diagnose. The use of standard
techniques along with a vaginogram or radiologically viewing the vaginal vault with instillation of
contrast media.[6]
4 Treatment
Treatment options range from conservative treatment,
behavior management, bladder retraining,[10] pelvic oor
therapy, collecting devices (for men), xer-occluder
devices for incontinence (in men), medications and
surgery.[11] The success of treatment depends on the correct diagnoses.[12] Weight loss is recommended in those
who are obese.[13]
4.1 Exercises
4.2 Medications
TREATMENT
incontinence and are only recommended in those who Readjustable sling The re-adjustable sling consists of
have urge incontinence who do not improve with bladder a standard synthetic mesh sling combined with sutures
training.[13]
that attach to an implantable tensioning device that resides permanently under the skin in the abdominal wall.
Once implanted, this Readjustable Mechanical External
4.3 Surgery
(REMEEX) device can be re-accessed under local anesthesia to ne tune the sling should incontinence reappear
Surgery may be used to alleviate incontinence after other months or years after the initial surgery.[20]
treatments have been tried and found not to be eective. Urodynamic testing seems to conrm that surgical
restoration of vault prolapse can cure motor urge inconti- 4.3.2 Bladder repositioning
nence. In those with problems following prostate surgery
Most stress incontinence in women results from the bladthere is little evidence regarding the use of surgery.[19]
der dropping down toward the vagina. Therefore, common surgery for stress incontinence involves pulling the
4.3.1 Slings
bladder up to a more normal position. Working through
an incision in the vagina or abdomen, the surgeon raises
The procedure of choice for stress urinary incontinence the bladder and secures it with a string attached to musin females is what is called a sling procedure. A sling cle, ligament or bone. For severe cases of stress inconusually consists of a synthetic mesh material in the shape tinence, the surgeon may secure the bladder with a wide
of a narrow ribbon but sometimes a biomaterial (bovine sling. This not only holds up the bladder but also comor porcine) or the patients own tissue that is placed under presses the bottom if the bladder and the top of the urethe urethra through one vaginal incision and two small thra, further preventing leakage.
abdominal incisions. The idea is to replace the decient
pelvic oor muscles and provide a backboard of support
under the urethra.
4.3.3 Marshall-Marchetti-Krantz
Tension-free transvaginal tape The tension-free
transvaginal tape(TVT) sling procedure treats urinary
stress incontinence by positioning a polypropylene mesh
tape underneath the urethra. The 20-minute outpatient
procedure involves two miniature incisions and has
an 86-95% cure rate. Complications, such as bladder
perforation, can occur in the retropubic space if the
procedure is not done correctly. This minimally invasive
procedure is a common treatment for stress urinary
incontinence.
Transobturator tape The transobturator tape (TOT)
sling procedure aims to eliminate stress urinary incontinence by providing support under the urethra. This minimally invasive procedure eliminates retropubic needle
passage and involves inserting a mesh tape under the urethra through three small incisions in the groin area. While
the procedure has shown risks during its infancy, recent
developments have increased the cure rate to 90%.
5.1
Children
5
of bladder control products and to the health care system and nursing home industry. Injury related to incontinence is a leading cause of admission to assisted living
and nursing care facilities. More than 50% of nursing
facility admissions are related to incontinence.[27]
5.1 Children
Incontinence happens less often after age 5: About 10
percent of 5-year-olds, 5 percent of 10-year-olds, and 1
percent of 18-year-olds experience episodes of incontinence. It is twice as common in girls as in boys.
5.2 Women
Bladder symptoms aect women of all ages. However, bladder problems are most prevalent among older
women.[28] Women over the age of 60 years are twice
as likely as men to experience incontinence; one in three
women over the age of 60 years are estimated to have
[24]
Indwelling catheters (also known as foleys) are very of- bladder control problems. One reason why women are
ten used in hospital settings or if the user is not able to more aected is the weakening of pelvic oor muscles by
[29]
handle any of the above solutions himself. The indwelling childbirth.
catheter is typically connected to a urine bag that can be
worn on the leg or hang on the side of the bed. Indwelling
catheters need to be changed on a regular basis by a health 5.3 Men
care professional. The advantage of indwelling catheters
are, that the urine gets funneled away from the body keep- Men tend to experience incontinence less often than
ing the skin dry. The disadvantage, however, is that it is women, and the structure of the male urinary tract acvery common to get urinary tract infections when using counts for this dierence. It is common with prostate
cancer treatments. Both women and men can become
indwelling catheters.[23]
incontinent from neurologic injury, congenital defects,
Intermittent catheters are single use catheters that are strokes, multiple sclerosis, and physical problems assoinserted into the bladder to empty it, and once the blad- ciated with aging.
der is empty they are removed and discarded. Intermittent catheters are primarily used for retention (inability While urinary incontinence aects older men more often
to empty the bladder) but for some people can be used to than younger men, the onset of incontinence can happen
at any age. Estimates in the mid-2000s suggested that 17
reduce / avoid incontinence.
percent of men over age 60, an estimated 600,000 men,
experienced urinary incontinence, with this percentage
increasing with age.[30]
Fixer-occluder devices (for men) are strapped around
the penis, softly pressing the urethra and stopping the ow
of urine. This management solution is only suitable for
light or moderate incontinence.
Epidemiology
7 References
[1] Managing Urinary Incontinence. National Prescribing
Service, available at http://www.nps.org.au/health_
professionals/publications/nps_news/current/nps_news_
66_managing_urinary_incontinence_in_primary_care
[2] see
[www.medicaldictionaryweb.com/
Enuresis-definition/]
[3] merck.com > Polyuria: A Merck Manual of Patient
Symptoms podcast. Last full review/revision September
2009 by Seyed-Ali Sadjadi, MD
[4] What is urinary incontinence? Family Doctor. Retrieved
on 2010-03-02
[5] Walid MS, Heaton RL (2009).
Stepwise Multimodal Treatment of Mixed Urinary Incontinence
with Voiding Problems in a Patient with Prolapse.
Journal of Gynecologic Surgery 25 (3): 121127.
doi:10.1089/gyn.2009.0014.
[6] Macaluso JN, Appell RA, Sullivan JW: Ureterovaginal
stula detected by vaginogram. JAMA. 246:1339-1340,
1981
[7] Functional incontinence. Australian Government Department of Health and Ageing. 2008. Archived from the
original on 2008-07-23. Retrieved 2008-08-29.
[8] Shamliyan, T; Wyman, J; Bliss, DZ; Kane, RL; Wilt, TJ
(December 2007). Prevention of urinary and fecal incontinence in adults.. Evidence report/technology assessment (161): 1379. PMID 18457475.
[9] Karlovsky, Matthew E. MD, Female Urinary Incontinence
During Sexual Intercourse (Coital Incontinence): A Review, The Female Patient (retrieved 22 August 2010)
[10] Bladder retraining ichelp.org Interstitial Cystitis Association Accessed July 13, 2012
[11] Clinical audit of the use of tension-free vaginal tape
as a surgical treatment for urinary stress incontinence,
set against NICE guidelines. Price N and Jackson
SR. J Obstet Gynaecol, Aug 2004; 24(5): 534538http://www.oxfordgynaecology.com/Conditions/
Urinary-Incontinence.aspx
[12] What is Male Urinary Incontinence? Retrieved on 201003-02
[13] Qaseem, A; Dallas, P; Forciea, MA; Starkey, M; Denberg, TD; Shekelle, P; for the Clinical Guidelines Committee of the American College of, Physicians (Sep 16,
2014). Nonsurgical Management of Urinary Incontinence in Women: A Clinical Practice Guideline From
the American College of Physicians.. Annals of internal medicine 161 (6): 429440. doi:10.7326/m13-2410.
PMID 25222388.
[14] How to Use Vaginal Weights. National Incontinence.
Retrieved 10 October 2012.
[15] Hirakawa, T; Suzuki, S; Kato, K; Gotoh, M; Yoshikawa,
Y (2013-01-11).
Randomized controlled trial of
pelvic oor muscle training with or without biofeedback for urinary incontinence.
Int Urogynecol J.
doi:10.1007/s00192-012-2012-8. PMID 23306768.
[16] Fitz, Ftima Fan; Resende, Ana Paula Magalhes; Stpp,
Liliana; Costa, Thas Fonseca; Sartori, Marair Gracio Ferreira; Giro, Manoel Joo Batista Castello; Castro, Rodrigo Aquino (November 2012). Efeito da
REFERENCES
External links
Urinary incontinence at DMOZ
Urinary Incontinence Information
Continence Coach from Ostomy Wound Management
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9.2
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9.3
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