Академический Документы
Профессиональный Документы
Культура Документы
Spring 2015
Lectures: Tuesday, Thursday 4:55-6:10. GCASL C95
Recitations: Sections by registration (see following page)
Required textbook
Matthews, Van Holde, Appling and Anthony-Cahill Biochemistry 4th Edition Pearson,
2013. (MVAA)
Miguel Perreira
Sabrine Obbad
Jon Kwok
miguel.pereira@nyu.edu
sio206@nyu.edu
jgk298@nyu.edu
Recitation Sections
Section Name
101 Pereira
102 Obbad
103 Pereira
104 Pereira
105 Kwok
106 Pereira
Schedule
Tuesday
2:00 PM to 3:15 PM
Thursday
6:20 PM to 7:35 PM
Tuesday
6:20 PM to 7:35 PM
Thursday
8:00 AM to 9:15 AM
Monday
9:30 AM to 10:45 AM
Thursday
3:30 PM to 4:45
Location
Meyer 261
194 Mercer
Room 308
GCASL 388
Waverly 569
Meyer 261
25W4th C-9
Points
Midterm 1
100
Midterm 2
100
Final exam
150
100
Project report
50
Class website: This course is on NYU Classes. Notes, readings, problem sets, study
guides, modules and web links as well as answers to problems will all be posted on
the web.
Academic Integrity and Plagiarism: The instructors for this course have no tolerance
for plagiarism in any manifestation. NYU policy on plagiarism will be enforced with
great vigil. Students who fail to conform to NYUs standards on academic integrity
will be subject to stringent disciplinary action. Inform yourself in advance of proper
academic conduct. In brief (and quoting from the College of Arts & Science policy!),
Academic honesty means that the work you submit in whatever form is original.
When in doubt, ask. Please inform yourself of our policy:
http://cas.nyu.edu/page/academicintegrity
Learning Center Help:
Free peer tutoring, Study Slams, group reviews, workshops, and more.
University Learning Center
www.nyu.edu/ulc
ULC@Academic Resource Center, 18 Washington Place, Lower LevelULC@UHall,
110 East 14th Street, top of stairs by UHall Commons
Soomie Han, J.D.
Assistant Dean
Academic Support Services
Director, University Learning Center
NYU College of Arts & Science
SCHEDULE OF LECTURES
Lecture
Date
Jan. 27 T
1, Jan. 29
R
TOPIC
RECITATION
Snow Day
Overview & Introduction
Matrix of Life
2, Feb. 3 T Bioenergetics
TOOLS: Electrophoresis
3, Feb. 5 R Proteins I Amino acids &
polypeptides
TOOLS: Expression and
purification of proteins
4, Feb. 10
Proteins II Structure and
T
folding
TOOLS: Proteomics
5, Feb. 12
Protein function and
R
evolution
TOOLS: Immunological
methods
6, Feb. 17
Carbohydrates
T
7, Feb. 19
Lipids, membranes and
R
transport
TOOLS: Techniques for
membrane studies
8,Feb. 24 T Enzymes I Kinetics and
mechanism
TOOLS: How to measure rates
Engineering enzymes
Enzymes: II Inhibition and
9, Feb. 26
Regulation
R
Mar. 3 T
MIDTERM 1 - Ch. 2, 3, 5-10
10, Mar. 5
R
READING
Chemical Logic of
Metabolism
TOOLS: Radio-isotopes
Metabolomics
Ch. 1,2
Ch. 3
Rec. 1
Ch. 5
Ch.6
Rec. 2
PR 1-3 to 1-9
Ch.7, 8
PR 1-2 114,1-15, 1-20
Ch. 9
Rec. 3
Ch. 10
PR1-11
Ch. 11
PR 2-6, 2-13
Ch. 11, 12
PR 2-8,
3-11,12,13
Ch. 12
Rec. 4
11 Mar. 10
T
Carbohydrate metabolism
TOOLS: Protein-protein
interactions
12, Mar. 12 Gluconeogenesis
R
13 Mar 24T TCA cycle
Ch. 13
PR 3-18
14 Mar. 26
R
Ch. 15, 18
Oxidative phosphorylation
Coordination of energy
metabolism
Signal Transduction
15, Mar.
31, T
16, Apr. 2, DNA Intro
TOOLS: Manipulating DNA
R
18 Apr. 7 T MIDTERM EXAM II
Ch. 11-15, 18
17 Apr. 9,
DNA replication
TOOLS: PCR
R
18, Apr. 14 DNA restructuring
T
19, Apr. 16 RNA synthesis & processing
R
I
TOOLS: Footprinting
Mapping start sites
20, Apr. 21 RNA synthesis & processing
T
II
TOOLS: DNA microarrays
Chromatin Immunoprecipitation
21, Apr. 23 Protein synthesis I
R
22, Apr. 28 Protein synthesis II
T
23, Apr. 30 Control of gene expression I
R
24, May 5
Control of gene expression II
TOOLS: Mapping complex
T
structures
26, May 7
Review
R
May 13-19 FINAL EXAM comprehensive
Tuesday, 5/14 subject to
verification
Rec. 5
Ch. 13
Ch. 14
Ch. 23
Rec. 6
Ch. 4
Ch. 25
Ch. 26
Rec. 7
Ch. 27
Ch, 27
Rec. 8
Ch. 28
Ch. 28
Rec. 9
Ch. 29
Ch. 29
Ch. 25-29
REVIEW