DRUG STUDY ON PPUD

Patients Medications:

Lipids
Amino Acids
Cefoxitin
Omeprazole
Tramadol
Mupirocin

CEFOXITIN
-

This medication is a broad-spectrum cephalosporin antibiotic, prescribed for serious

infections such as respiratory tract infection, urinary tract infection, septicemia, and
others. It works by fighting against the bacteria in the body.

S.E.:
Local Reactions - Swelling (inflammation) of vein.
Allergic Reactions - Rash, hives, flushing, itching, eosinophilia, fever, difficulty in breathing,
and other allergic reactions including anaphylaxis, and angioedema.
Heart - Low blood pressure.
Gastrointestinal - Diarrhea, nausea and vomiting.
Central Nervous System - Myasthenia gravis.
Blood - Eosinophilia, decrease in white blood cells, platelets, anemia, and bone
marrowdepression.
Liver Function - Elevations in liver enzymes.
OMEPRAZOLE

Omeprazole (Prilosec, Zegerid) belongs to group of drugs called proton pump inhibitors. It
decreases the amount of acid produced in the stomach. Omeprazole is used to treat symptoms
of gastroesophageal reflux disease (GERD) and other conditions caused by excess stomach
acid. It is not for immediate relief of heartburn symptoms. Omeprazole is also used to promote
healing of erosive esophagitis (damage to your esophagus caused by stomach acid).
Omeprazole may also be given together with antibiotics to treat gastric ulcer caused by infection
with helicobacter pylori (H. pylori).

S.E.:
Get emergency medical help if you have any of these signs of an allergic reaction to
omeprazole: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:

diarrhea that is watery or bloody; or

low magnesium (dizziness, confusion, fast or uneven heart rate, jerking muscle
movements, jittery feeling, muscle cramps, muscle weakness or limp feeling, cough or
choking feeling, seizure).

Common omeprazole side effects may include:

fever;
cold symptoms such as stuffy nose, sneezing, sore throat;
stomach pain, gas;
nausea, vomiting, mild diarrhea; or
headache.
TRAMADOL

Actions

Centrally acting opiate receptor agonist that inhibits the uptake of norepinephrine and
serotonin, suggesting both opioid and nonopioid mechanisms of pain relief. May produce
opioid-like effects, but causes less respiratory depression than morphine.
Therapeutic Effects

Effective agent for control of moderate to moderately severe pain.

Tramadol inhibits reuptake of norepinephrine, serotonin and enhances serotonin release.

It alters perception and response to pain by binding to mu-opiate receptors in the CNS.

Adverse Effects

CNS: Drowsiness, dizziness, vertigo, fatigue, headache, somnolence, restlessness,

euphoria, confusion, anxiety, coordination disturbance, sleep disturbances, seizures.
CV: Palpitations, vasodilation.
GI: Nausea, constipation, vomiting, xerostomia, dyspepsia, diarrhea, abdominal pain,
anorexia, flatulence.
Body as a Whole: Sweating, anaphylactic reaction (even with first dose), withdrawal
syndrome (anxiety, sweating, nausea, tremors, diarrhea, piloerection, panic attacks,
paresthesia, hallucinations) with abrupt discontinuation.
Skin: Rashes
Special Senses: Visual disturbances.
Urogenital: Urinary retention/frequency, menopausal symptoms.
MUPIROCIN

Mupirocin is an antibiotic that is used topically (on the skin) for the treatment of impetigo, a
bacterial disease of the skin caused by Staphylococcus aureus, beta-hemolytic
streptococcus andStreptococcus pyogeneaas.
S.E.:

Serious side effects are not expected to occur with mupirocin topical therapy. Stop using
mupirocin topical and see your doctor if you experience unusual blistering, itching, redness,
peeling, dryness, or irritation of the skin.