Generic Name

(Brand name)

Mechanism of
Action

Generic Name:
Ipratropium +
Salbutamol

Combivent UDVs
contain two active
ingredients,
ipratropium bromide
and salbutamol
sulphate, both of
which are
bronchodilators.
Combivent UDVs
are used to treat
people suffering
from chronic
obstructive
pulmonary disease,
who require regular
treatment with
ipratropium and
salbutamol.

Brand Name:

Dosage and
Frequency:

Nebulization
Q4
Drug Class:
Anti-asthmatic
and COPD
Preparations.

Salbutamol belongs
to a group of
medicines called
short-acting beta 2
agonists. It works by

Date
Ordered/
Administe
red
February 26,
2015

Indications

Salbutamol and
ipratropium belong
to the family of
medications known
asbronchodilators.
Together, they are
used to treat chronic
obstructive
pulmonary disease
(COPD), a chronic
lung disease that
makes it difficult to
breathe. These
medications work in
different ways to
open the airways
and make breathing
easier.

Contraindications

Adverse effects

Allergy to ipratropium Coughing

bromide or related
headache
medicines, eg atropine. nausea
Change in sense of taste
Fast, abnormal heart
dizziness
rhythms
dryness of mouth
(tachyarrhythmias).
nervousness
tremor
Heart disease
Angioedema (swelling
characterised by
of the face,lips, or
thickening of the
eyelids)
internal heart muscle
bronchospasm,
and a blockage inside
paradoxical or
the heart (hypertrophic hypersensitivity
obstructive
induced(shortness of
cardiomyopathy).
breath;wheezing)
chest discomfort or
This medicine is not
pain
recommended for
irregular
children and
heartbeat
adolescents under 12
oropharyngeal
years of age, as there is edema (swelling of the
no information
mouth or throat)
regarding its safety and skin rash

NURSI
RESPO

Protect solu
inhalation f

Store unuse
pouch.

Use nebuliz
instead of f
avoid blurr
aggravation
angle glauc

Can mix al
nebulizer fo

Ensure ade
control env
temperature
hyperpyrex

Have patien
taking med
urinary rete

acting on receptors
in the lungs called
beta 2 receptors.
Stimulation of these
receptors causes the
muscles in the
airways to relax,
allowing the airways
to open.
Ipratropium bromide
is a type of medicine
known as an
antimuscarinic
bronchodilator. It
works by blocking
different types of
receptors, called
muscarinic
receptors, which are
found on the muscle
surrounding the
airways in the lungs.
Stimulation of these
receptors by a
natural chemical
called acetylcholine
normally causes the
muscle in the
airways to contract,

efficacy in this age

group.
Pregnancy
Breastfeeding.

tachycardia (fast
heartbeat)
urticaria (hives)

Advise pati
rash, eye pa
voiding, pa
changes.

and this makes the

airways narrow.
Depending on how
much the receptors
are stimulated, this
can cause difficulties
breathing, as is seen
in asthma and
bronchitis. As
ipratropium blocks
the receptors, it
stops the action of
acetylcholine and
allows the airways
to open, making it
easier to breathe.